Southern Illinois Holidays from £1,183

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Photo by Southernmost Illinois Tourism Bureau

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Your Southern Illinois Holiday

Design the adventure you've always longed for with a customised Southern Illinois holiday package. A great starting point is Belleville, where you'll experience culture, history and other highlights. Kick off your trip to Southern Illinois with some time exploring O'Fallon visiting popular attractions like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that lures travellers from far and wide. Lake Sara and Effingham Performance Centre are two of the top places to see in this destination. Expedia is your one-stop shop for organising your Southern Illinois holiday. From accommodation and flights, to activities and rental cars, we know how to create a travel experience like no other.

Top Southern Illinois Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
8.2/10 Very Good! (756 reviews)
I booked online and paid via the app. When I arrived on site they explained they had overbooked and had no rooms available. The staff was amazing and went above and beyond and secured a room at another location. Thank you to the staff for taking care of us.

Reviewed on 26 Jul 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
9/10 Wonderful! (1,549 reviews)
For the price, this hotel was great. A cheap clean stopover in St. Louis. We were very happy to have cafes and restaurants within walking distance too! And parking was free.

Reviewed on 30 Jul 2025

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
8.4/10 Very Good! (1,000 reviews)
The hotel room was comfortable and well-kept - it’s a good spot for a weekend getaway or a night before flying out from the airport. Good mix of slots and tables.

Reviewed on 24 Jul 2025

The Knight Center at Washington University

The Knight Center at Washington University

2.5 out of 5
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
9.4/10 Exceptional! (337 reviews)
Property was well kept and great location

Reviewed on 29 Jul 2025

Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
per person
18 Oct - 24 Oct
found 1 day ago
Return flight included
Manchester (MAN) to St. Louis (STL)
9/10 Wonderful! (1,783 reviews)
Nice visual look and fun encased collectibles to look at.

Reviewed on 29 Jul 2025

Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
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Eastport

While visiting Eastport, you might make a stop by sights like Gateway Conference Center and Splash City Family Waterpark.

Find hotels in Eastport

Southern Illinois Holiday Packages

Surrounded on three sides by powerful rivers, this region is richly textured with antebellum estates, farmland, vineyards and tracts of protected forest.

Discover the unique identity of Southern Illinois, a region renowned for its riverside communities, historic estates, rolling plains and rich pasturage. Nicknamed Shawnee Forest Country for the vast tracts of forest and parkland that stretch downstate, Southern Illinois is studded with oak-hickory woods and hardy palms. Explore the area along a network of trails that showcase its natural scenery, heritage grandeur and regional wineries.

Southern Illinois is strewn with historic townships nestled within the lush greenery. Visit Cairo to experience the romance of a preserved 19th-century river town and learn about the region’s Civil War history. MetropolisOpens in a new window is an intriguing little town that is heralded as the home of Superman. Visit the Super MuseumOpens in a new window to learn about the world-famous DC Comics superhero. At the village of Cave-in-RockOpens in a new window, you can discover the area’s enduring connection with the Ohio River and visit a vast limestone cave once used as a hideout by river pirates.

Pretty Makanda is the gateway to Giant City State Park, a stunning preserve peppered with enormous sandstone bluffs known as the Giant City Streets. More breathtaking natural scenery can be found in the Shawnee National Forest within the Ozark and Shawnee hills. Go on a zip-lining tour, hike scenic trails and ride on a bike or on horseback through towering canyons and dense forests. The park’s waterways are also ideal for canoeing, boating and fishing. Learn about awe-inspiring geology on a walking trail through the Garden of the Gods. Discover a unique landscape of floodplain forests in the Cache River Wetlands, which is renowned for its cypress swamps and diverse birdlife.

Southern Illinois has an extensive network of scenic trails and byways. Explore the Shawnee Hills Wine Trail to reach 12 wineries offering sumptuous tastings or check out the heritage riverside towns on the Ohio River Scenic Byway. Leave the car at home and travel from Harrisburg to Karnak on a bicycle or cross-country skis along the former railroad bed of Tunnel Hill State Trail.

Reach Southern Illinois by plane to Lawrenceville-Vincennes International Airport or catch the Amtrak service to Carbondale or St. Louis in neighboring Missouri. Stay overnight in heritage homestead accommodation or pitch a tent in one of the region’s stunning state parks.

Southern Illinois Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)

Top hotels in Southern Illinois

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is £58 per night from 3 Aug to 4 Aug
£58
3 Aug - 4 Aug
includes taxes & fees
7.8/10 Good! (464 reviews)
"You get what you pay for"

Reviewed on 27 Jul 2025

Red Lion Inn & Suites Pontoon Beach
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is £80 per night from 10 Aug to 11 Aug
£80
10 Aug - 11 Aug
includes taxes & fees
9.6/10 Exceptional! (1,412 reviews)
"The staff was helpful and friendly. Room was clean"

Reviewed on 29 Jul 2025

Drury Plaza Hotel Mt. Vernon
Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach

3 out of 5
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is £75 per night from 3 Aug to 4 Aug
£75
3 Aug - 4 Aug
includes taxes & fees
8.4/10 Very Good! (714 reviews)
"It was roomy and clean."

Reviewed on 27 Jul 2025

Best Western Plus Pontoon Beach
See all 1,042 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Popular places to visit

Garden of the Gods Recreation Area

Garden of the Gods Recreation Area

See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.

Garden of the Gods Recreation Area
Superman Statue which includes a statue or sculpture as well as a small group of people

Superman Statue

Superman fans will love getting a photograph taken in front of this giant statue of the Man of Steel himself, dressed in his iconic red-and-blue guise.

Superman Statue

Frequently asked questions

How much does a Southern Illinois travel package cost?
Perhaps less than you imagined — from just £1,183, as a matter of fact! By combining hotels, flights and car rentals into a customized travel package, your trip to Southern Illinois is just a few clicks away.
If I'm not able to travel, can I cancel my Southern Illinois travel package?
If your travel plans in Southern Illinois have changed, it's a relief to know that it's possible to cancel your booking. If you made your booking in the last 24 hours, you may be able to receive a refund. If your booking is older than that, your airline, hotel or car rental company may charge a cancellation fee. For more information, check our Customer Service Portal.
How do I get a cheap travel package to Southern Illinois?
Our Southern Illinois travel packages offer plenty of savings for the savvy wanderer. For the best deal, simply bundle your flights, hotels and extras (including activities) into a budget-friendly package. But low prices are just the beginning of your next memorable adventure. Book with Expedia and you'll have more than 550 air carriers and 1,000,000 hotels across the globe to pick from. No matter your budget, there's a travel package that's perfect for you.
Does Expedia offer Book Now, Pay Later Southern Illinois holidays?
Your bank balance shouldn't get in the way of taking a holiday, so Expedia has devised a solution to help. Now that we've teamed up with online lender Klarna, it's easier than ever to book a fantastic getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Consider one of these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month is something that would work for you, Klarna offers just that! Paying in easy monthly instalments will make that dream getaway possible.
  • Pay in instalments holidays: If you'd like to pay off your getaway across multiple transactions, holidays paid in instalments might be the right choice for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: Clicking on the "book now" button is easier with this plan. Just put down a small deposit on your escape and then start packing your bags.

How far in advance should I book my Southern Illinois holiday?
While not all air carriers advertise tickets early, customers are usually able to start comparing international fares on Expedia up to a year in advance. This is the time when you can nab some incredible bargains. If you're booking last minute, you might still be in luck. Discounted prices occasionally appear only weeks prior to departure.
What does an Expedia Southern Illinois travel package include?
That depends on what you're after. If you're travelling solo, you might decide to bundle hotels and flights. Bringing the entire family to Southern Illinois? A travel package including flights, hotels and rental cars might be a better fit. Expedia gives you the freedom to customize your travel package.
What should I know before booking a Southern Illinois travel package?
Get ready to save with an Expedia travel package. Combine your flights, rental cars and hotels and score terrific discounts. You're not limited to hotels, however. Book with us and choose from beachside villas, cabins in the mountains and just about everything in between!
Can I choose my airline with a Southern Illinois Expedia travel package?
You can, and with more than 550 airlines to choose from across the globe, you're not short on choice. Search the available options and see which airline best fits your budget and needs.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.