Southern Illinois Holidays

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Photo by Southernmost Illinois Tourism Bureau

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    Packages with flights are ATOL protected

Your Southern Illinois Holiday

Design the adventure you've always longed for with a customised Southern Illinois holiday package. A great starting point is Belleville, where you'll experience culture, history and other highlights. Kick off your trip to Southern Illinois with some time exploring O'Fallon visiting popular attractions like O'Fallon Family Sports Park and FanDuel Sportsbook and Horse Racing. Effingham is another city that lures travellers from far and wide. Lake Sara and Effingham Performance Centre are two of the top places to see in this destination. Expedia is your one-stop shop for organising your Southern Illinois holiday. From accommodation and flights, to activities and rental cars, we know how to create a travel experience like no other.

Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
An aerial view of a city with a prominent river, a large bridge, and surrounding buildings.

Eastport

While visiting Eastport, you might make a stop by sights like Splash City Family Waterpark and Gateway Conference Center.

Find hotels in Eastport

Southern Illinois Holiday Packages

Surrounded on three sides by powerful rivers, this region is richly textured with antebellum estates, farmland, vineyards and tracts of protected forest.

Discover the unique identity of Southern Illinois, a region renowned for its riverside communities, historic estates, rolling plains and rich pasturage. Nicknamed Shawnee Forest Country for the vast tracts of forest and parkland that stretch downstate, Southern Illinois is studded with oak-hickory woods and hardy palms. Explore the area along a network of trails that showcase its natural scenery, heritage grandeur and regional wineries.

Southern Illinois is strewn with historic townships nestled within the lush greenery. Visit Cairo to experience the romance of a preserved 19th-century river town and learn about the region’s Civil War history. MetropolisOpens in a new window is an intriguing little town that is heralded as the home of Superman. Visit the Super MuseumOpens in a new window to learn about the world-famous DC Comics superhero. At the village of Cave-in-RockOpens in a new window, you can discover the area’s enduring connection with the Ohio River and visit a vast limestone cave once used as a hideout by river pirates.

Pretty Makanda is the gateway to Giant City State Park, a stunning preserve peppered with enormous sandstone bluffs known as the Giant City Streets. More breathtaking natural scenery can be found in the Shawnee National Forest within the Ozark and Shawnee hills. Go on a zip-lining tour, hike scenic trails and ride on a bike or on horseback through towering canyons and dense forests. The park’s waterways are also ideal for canoeing, boating and fishing. Learn about awe-inspiring geology on a walking trail through the Garden of the Gods. Discover a unique landscape of floodplain forests in the Cache River Wetlands, which is renowned for its cypress swamps and diverse birdlife.

Southern Illinois has an extensive network of scenic trails and byways. Explore the Shawnee Hills Wine Trail to reach 12 wineries offering sumptuous tastings or check out the heritage riverside towns on the Ohio River Scenic Byway. Leave the car at home and travel from Harrisburg to Karnak on a bicycle or cross-country skis along the former railroad bed of Tunnel Hill State Trail.

Reach Southern Illinois by plane to Lawrenceville-Vincennes International Airport or catch the Amtrak service to Carbondale or St. Louis in neighboring Missouri. Stay overnight in heritage homestead accommodation or pitch a tent in one of the region’s stunning state parks.

Southern Illinois Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)

Top hotels in Southern Illinois

Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

3 out of 5
12 Ludwig Dr Fairview Heights IL
Fully refundableReserve now, pay when you stay
The price is £76 per night from 23 Aug to 24 Aug
£76
23 Aug - 24 Aug
includes taxes & fees
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3 out of 5
2706 W DeYoung St Marion IL
Fully refundableReserve now, pay when you stay
The price is £90 per night from 23 Aug to 24 Aug
£90
23 Aug - 24 Aug
includes taxes & fees
9.4/10 Exceptional! (1,012 reviews)
"Wonderful staff! My go to hotel when we travel down south."

Reviewed on 24 Jul 2026

Drury Inn & Suites Marion
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.5 out of 5
145 North 44th Street  Mount Vernon IL
Fully refundableReserve now, pay when you stay
The price is £94 per night from 6 Aug to 7 Aug
£94
6 Aug - 7 Aug
includes taxes & fees
Drury Plaza Hotel Mt. Vernon
See all 1,160 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
See properties

Frequently asked questions

How much does a Southern Illinois travel package cost?
Perhaps less than you imagined — from just , as a matter of fact! By combining hotels, flights and car rentals into a customized travel package, your trip to Southern Illinois is just a few clicks away.
If I'm not able to travel, can I cancel my Southern Illinois travel package?
If your travel plans in Southern Illinois have changed, it's a relief to know that it's possible to cancel your booking. If you made your booking in the last 24 hours, you may be able to receive a refund. If your booking is older than that, your airline, hotel or car rental company may charge a cancellation fee. For more information, check our Customer Service Portal.
How do I get a cheap travel package to Southern Illinois?
Our Southern Illinois travel packages offer plenty of savings for the savvy wanderer. For the best deal, simply bundle your flights, hotels and extras (including activities) into a budget-friendly package. But low prices are just the beginning of your next memorable adventure. Book with Expedia and you'll have more than 550 air carriers and 1,000,000 hotels across the globe to pick from. No matter your budget, there's a travel package that's perfect for you.
Does Expedia offer Book Now, Pay Later Southern Illinois holidays?
Your bank balance shouldn't get in the way of taking a holiday, so Expedia has devised a solution to help. Now that we've teamed up with online lender Klarna, it's easier than ever to book a fantastic getaway without exhausting your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Consider one of these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month is something that would work for you, Klarna offers just that! Paying in easy monthly instalments will make that dream getaway possible.
  • Pay in instalments holidays: If you'd like to pay off your getaway across multiple transactions, holidays paid in instalments might be the right choice for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: Clicking on the "book now" button is easier with this plan. Just put down a small deposit on your escape and then start packing your bags.

How far in advance should I book my Southern Illinois holiday?
While not all air carriers advertise tickets early, customers are usually able to start comparing international fares on Expedia up to a year in advance. This is the time when you can nab some incredible bargains. If you're booking last minute, you might still be in luck. Discounted prices occasionally appear only weeks prior to departure.
What does an Expedia Southern Illinois travel package include?
That depends on what you're after. If you're travelling solo, you might decide to bundle hotels and flights. Bringing the entire family to Southern Illinois? A travel package including flights, hotels and rental cars might be a better fit. Expedia gives you the freedom to customize your travel package.
What should I know before booking a Southern Illinois travel package?
Get ready to save with an Expedia travel package. Combine your flights, rental cars and hotels and score terrific discounts. You're not limited to hotels, however. Book with us and choose from beachside villas, cabins in the mountains and just about everything in between!
Can I choose my airline with a Southern Illinois Expedia travel package?
You can, and with more than 550 airlines to choose from across the globe, you're not short on choice. Search the available options and see which airline best fits your budget and needs.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.