A forested valley with autumn foliage, a rocky cliff, and a sunset.

Compare and book 4 Star hotels in Southern Illinois, Illinois

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Check availability on Southern Illinois 4 Star Hotels

Tonight
26 Aug - 27 Aug
Tomorrow
27 Aug - 28 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

Our top choices for Southern Illinois 4-star hotels

An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.
A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.
An outdoor patio area with tables and chairs, large windows, and red umbrellas.
A spacious lobby with high ceilings, a wooden ceiling, and a large wall with vertical panels. There are seating areas with sofas and chairs, and a staircase on the right.

1. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
United States
Samuel
£113
includes taxes & fees
30 Aug - 31 Aug
DoubleTree by Hilton Mt. Vernon
A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.
A casino interior with slot machines, a large chandelier, and a carpeted floor.

2. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
United States
Sheila
£93
includes taxes & fees
2 Sept - 3 Sept
Walker's Bluff Casino Resort
A lobby with a central table, seating area, and a stone pillar with a mirror.
A modern hotel lobby with a sectional sofa, armchairs, a coffee table, and abstract wall art.
An outdoor patio with wicker furniture, a stone fire pit, and potted plants.
A restaurant with multiple tables, chairs, and a stone fireplace.

3. DoubleTree by Hilton Collinsville - St. Louis

DoubleTree by Hilton Collinsville - St. Louis
Eastport
United States
Timothy
£110
includes taxes & fees
30 Aug - 31 Aug
DoubleTree by Hilton Collinsville - St. Louis
A cozy living room with a leather sofa, a fireplace, and a chandelier.
A hotel room with a large bed, a desk, a chair, a television, and a painting on the wall.
A living room with a brown leather sofa, a beige armchair, and a matching ottoman. There are two side tables with lamps, a chandelier, and a framed portrait on the wall.
A two-story house with a porch, a brick foundation, and an American flag.

4. Charleston House Bed & Breakfast Inn

Charleston House Bed & Breakfast Inn
Charleston
United States
Amanda
£103
includes taxes & fees
30 Aug - 31 Aug
Charleston House Bed & Breakfast Inn
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Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois
A forested valley with autumn foliage, a rocky cliff, and a sunset.
Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews

DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon

10/10 Excellent
"What a beautiful place to stay! Our room was spacious and clean. Breakfast was fantastic!"
Alicia 1-night trip
Posted 3 days ago
DoubleTree by Hilton Mt. Vernon

Find out more about Southern Illinois

Frequently asked questions

What are the best 4-star hotels in Southern Illinois?
Based on reviews by Expedia travellers, DoubleTree by Hilton Collinsville - St. Louis is among the most popular in Southern Illinois. Offering lots of handy amenities and an outstanding guest experience, this 4-star hotel in Collinsville is hard to beat.
How much does it cost to stay in a 4-star hotel in Southern Illinois?
To find a 4-star hotel in Southern Illinois that matches your budget, make use of Expedia's handy search filters. Check out what's available during your chosen dates and use our pricing filter to set your limit. You can also list your results by the most economical option first.
  • Search for the lowest price from £93
What's the difference between 5-star and 4-star hotels in Southern Illinois?
If you choose to stay at a 4-star hotel in Southern Illinois, you'll usually find plenty of amenities to ensure you're comfortable, such as a gym, pool and restaurant. You can enjoy high-quality service and upmarket surroundings. Go for a 5-star hotel and you'll get a few more perks — think concierge assistance, on-site spas and indulgent turndown services. You're likely to get additional amenities and first-class services at a 5-star stay, but both are superb options for luxury travellers.

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