Title: The 10 Best 4 Star Hotels in Southern Illinois - 2026 Updated Prices | Expedia.co.uk [Southern Illinois Travel Guide](https://expedia.co.uk/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Holiday Rentals in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Holiday-Rentals.d6233859.Travel-Guide-HolidayRentals)[Flights to Southern Illinois](https://expedia.co.uk/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Illinois.d6233859.Car-Hire-Guide)[Southern Illinois Holidays](https://expedia.co.uk/Southern-Illinois.d6233859.Holidays-City-Breaks) ![Southern Illinois featuring landscape views, a sunset and forest scenes](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Southernmost Illinois Tourism Bureau # Compare and book 4 Star hotels in Southern Illinois, Illinois - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Illinois 4 Star Hotels Tonight [10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-01-10&endDate=2026-01-11&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-01-11&endDate=2026-01-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-01-16&endDate=2026-01-18&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-01-23&endDate=2026-01-25&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southern Illinois 4-star hotels ![Indoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/5600/5553/5af8e624.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5600/5553/25ca1c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5600/5553/7cac1c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/5600/5553/ec25eb2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Mt. Vernon [](https://www.expedia.co.uk/Mount-Vernon-Hotels-DoubleTree-By-Hilton-Mt-Vernon.h5553.Hotel-Information) Mount Vernon 8.4/10 Very good (770 reviews) "What stood out for us were the amenities. This hotel has amazing spaces for meetings or conversation groups. The breakfast buffet was amazing. And there were the cookies!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Glenn £107 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/Mount-Vernon-Hotels-DoubleTree-By-Hilton-Mt-Vernon.h5553.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27100/27006/579b996f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/30000/27100/27006/a497be51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Courtyard View | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/27100/27006/050895e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/27100/27006/35f1a1de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Collinsville - St. Louis [](https://www.expedia.co.uk/Collinsville-Hotels-DoubleTree-By-Hilton-Collinsville-St-Louis.h27006.Hotel-Information) Eastport 8.2/10 Very good (1,001 reviews) "Nice restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shelly £107 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Collinsville-Hotels-DoubleTree-By-Hilton-Collinsville-St-Louis.h27006.Hotel-Information) ![Sauna, hot tub, body treatments, hot stone massages](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/8fcd4708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/2902012c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/84958281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/3a123ac6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walker's Bluff Casino Resort [](https://www.expedia.co.uk/Carterville-Hotels-Walkers-Bluff-Casino-Resort.h97064786.Hotel-Information) Carterville 9.4/10 Exceptional (397 reviews) "Clean & friendly place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beverly £95 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Carterville-Hotels-Walkers-Bluff-Casino-Resort.h97064786.Hotel-Information) ![Honeymoon Suite, 1 King Bed, Non Smoking, Courtyard View | View from room](https://images.trvl-media.com/lodging/34000000/33420000/33418200/33418130/3020a524.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/34000000/33420000/33418200/33418130/35e8d6b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Suite, 1 King Bed, Non Smoking, Courtyard View | 1 bedroom, premium bedding, individually decorated](https://images.trvl-media.com/lodging/34000000/33420000/33418200/33418130/98f3a3b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Romantic Suite, 1 King Bed, Non Smoking | View from room](https://images.trvl-media.com/lodging/34000000/33420000/33418200/33418130/8a6c5ee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Davie School Inn [](https://www.expedia.co.uk/Anna-Hotels-Davie-School-Inn.h33418130.Hotel-Information) Anna 10/10 Exceptional (51 reviews) "very friendly hosts, great bfasts, excellent stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca [](https://www.expedia.co.uk/Anna-Hotels-Davie-School-Inn.h33418130.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Southern-Illinois-Hotels.s40-0-d6233859.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Southern-Illinois-Hotels.s40-0-d6233859.Travel-Guide-Filter-Hotels) ## Learn more about Southern Illinois Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes. [See all hotels in Southern Illinois](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-25&endDate=2026-01-26&adults=2®ionId=6233859) ![Southern Illinois featuring landscape views, a sunset and forest scenes](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by Southernmost Illinois Tourism Bureau ## Top Southern Illinois Hotel Reviews ## Find out more about Southern Illinois ## Frequently asked questions ### What are the best 4-star hotels in Southern Illinois? ### How much does it cost to stay in a 4-star hotel in Southern Illinois? > - Search for the lowest price from £95 ### What's the difference between 5-star and 4-star hotels in Southern Illinois? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [3 Star Hotels in Paris ](https://www.expedia.co.uk/3Star-Paris-Hotels.s30-0-d143485.Travel-Guide-Filter-Hotels) - 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