Photo by Southernmost Illinois Tourism Bureau
Compare and book 4 Star hotels in Southern Illinois, Illinois
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southern Illinois 4 Star Hotels
Our top choices for Southern Illinois 4-star hotels
9.4 out of 10, Exceptional, (428 reviews)
"Great place!"
Paula
The price is £97
includes taxes & fees
14 Apr - 15 Apr
8.2 out of 10, Very good, (1,000 reviews)
"This is a nice place to stay. We liked the convenience of walking easily to the convention center. The kids loved the pool too."
James
The price is £113
includes taxes & fees
11 May - 12 May
8.4 out of 10, Very good, (804 reviews)
"Easy parking, clean hotel, great breakfast"
Keni
The price is £107
includes taxes & fees
16 Apr - 17 Apr
10.0 out of 10, Exceptional, (3 reviews)
"Beautifully restored property. Clean and comfortable room, bed, and linens.
Wonderful, delicious breakfast prepared and served by the friendly proprietor."
peter
The price is £91
includes taxes & fees
20 Apr - 21 Apr
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews
Find out more about Southern Illinois
Frequently asked questions
Explore a world of travel with Expedia
- 3 Star Hotels in Paris
- 4 Star Hotels in Swansea
- 5 Star Hotels in Carmi
- 5 Star Hotels in Marissa
- Addieville Hotels
- Bartelso Hotels
- Benton Hotels
- Bluford Hotels
- Cabin Rentals in Carlyle
- Carlyle Hotels
- Centralia Hotels
- Cisne Hotels
- Dix Hotels
- Du Quoin Hotels
- Elkville Hotels
- Enfield Hotels
- Ewing Hotels
- Fairfield Hotels
- Flora Hotels
- Herrin Hotels
- Hoyleton Hotels
- Ina Hotels
- Johnston City Hotels
- Kinmundy Hotels
- Macedonia Hotels
- Mcleansboro Hotels
- Gay-Friendly Hotels in Mount Vernon
- Mount Vernon Hotels
- Nashville Hotels
- Odin Hotels
- Opdyke Hotels
- Patoka Hotels
- Pinckneyville Hotels
- Rinard Hotels
- Gay-Friendly Hotels in Salem
- Salem Hotels
- Sesser Hotels
- Sims Hotels
- Caravan Parks in Southwest Illinois
- Adults Only Resorts & in Southwest Illinois
- Pet-Friendly Hotels in Southwest Illinois
- Spa Hotels in Southwest Illinois
- Southwest Illinois Hotels
- Villas in Southwest Illinois
- Tamaroa Hotels
- Waltonville Hotels
- West City Hotels
- West Frankfort Hotels
- Gay-Friendly Hotels in Whittington
- Pet-Friendly Hotels in Whittington
- Whittington Hotels
- Lodges in Whittington
- Zeigler Hotels
- Flights to Flora
- Flights to Galatia
- Flights to Herrin
- Flights to Mount Vernon
- Flights to Odin
- Flights to Whittington
- Flights from Williamson County Regional
- Flights from Herrin
- Flights from Mount Vernon
- Flights from Christopher
- Flights from Elkville
- Flights from Kinmundy
- Flights from Opdyke
- Flights from Sims
- Flights from Tamaroa
- Flights from Waltonville
- Flights from Ewing
- Flights from West Frankfort
- Flights from Mill Shoals
- Flights from Walnut Hill
- Flights from Bonnie
- Flights from Dahlgren
- Flights from Macedonia
- Flights from Jeffersonville
- Flights from Jefferson County
- Flights from Benton
- Flights from Du Quoin
- Flights from London (LHR) to Marion (MWA)
- Flights from Manchester (MAN) to Marion (MWA)