Title: Cheap Car Hire in Southern Illinois, USA - Expedia.co.uk [Southern Illinois Travel Guide](https://expedia.co.uk/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Flights to Southern Illinois](https://expedia.co.uk/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Holidays](https://expedia.co.uk/Southern-Illinois.d6233859.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in Southern Illinois, USA ## Search and Compare from Car Companies in Southern Illinois Photo by Southernmost Illinois Tourism Bureau ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in Southern Illinois \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people Southern Illinois, Illinois, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southern%20Illinois,%20Illinois,%20United%20States%20of%20America&dpln=6233859&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people Southern Illinois, Illinois, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southern%20Illinois,%20Illinois,%20United%20States%20of%20America&dpln=6233859&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people Southern Illinois, Illinois, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southern%20Illinois,%20Illinois,%20United%20States%20of%20America&dpln=6233859&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people Southern Illinois, Illinois, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southern%20Illinois,%20Illinois,%20United%20States%20of%20America&dpln=6233859&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car hire in Southern Illinois [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Southern%20Illinois,%20Illinois,%20United%20States%20of%20America&dpln=6233859&date1=31/12/2025&date2=02/01/2026&crfrr=defaultFlex&SearchType=Place) ## Frequently asked questions ### What happens if I need to cancel my Southern Illinois car reservation? ### What types of cars can I rent in Southern Illinois? ### How do I find the best car hire deals in Southern Illinois with Expedia? ### How old do you have to be to rent a car in Southern Illinois? ### What do you need to rent a car in Southern Illinois? ### Can I hire a car for a month or longer in Southern Illinois? ### Where can I find a Southern Illinois hire car if I am younger than 25? ### Why should I rent a Southern Illinois car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - [Addieville Hotels ](https://www.expedia.co.uk/Addieville-Hotels.d3000420807.Travel-Guide-Hotels) - [Benton Hotels ](https://www.expedia.co.uk/Benton-Hotels.d6866.Travel-Guide-Hotels) - [Bluford Hotels ](https://www.expedia.co.uk/Bluford-Hotels.d3000346134.Travel-Guide-Hotels) - [Centralia Hotels ](https://www.expedia.co.uk/Centralia-Hotels.d55627.Travel-Guide-Hotels) - [Cisne Hotels ](https://www.expedia.co.uk/Cisne-Hotels.d3000346182.Travel-Guide-Hotels) - [Dix Hotels ](https://www.expedia.co.uk/Dix-Hotels.d6023670.Travel-Guide-Hotels) - [Du Quoin Hotels ](https://www.expedia.co.uk/Du-Quoin-Hotels.d98092.Travel-Guide-Hotels) - [Elkville Hotels ](https://www.expedia.co.uk/Elkville-Hotels.d3000346241.Travel-Guide-Hotels) - [Enfield Hotels ](https://www.expedia.co.uk/Enfield-Hotels.d3000433975.Travel-Guide-Hotels) - [Ewing Hotels ](https://www.expedia.co.uk/Ewing-Hotels.d3000434034.Travel-Guide-Hotels) - [Fairfield Hotels ](https://www.expedia.co.uk/Fairfield-Hotels.d177465.Travel-Guide-Hotels) - [Flora Hotels ](https://www.expedia.co.uk/Flora-Hotels.d178211.Travel-Guide-Hotels) - [Herrin Hotels ](https://www.expedia.co.uk/Herrin-Hotels.d183186.Travel-Guide-Hotels) - [Hoyleton Hotels ](https://www.expedia.co.uk/Hoyleton-Hotels.d3000346337.Travel-Guide-Hotels) - [Ina Hotels ](https://www.expedia.co.uk/Ina-Hotels.d3000434336.Travel-Guide-Hotels) - [Johnston City Hotels ](https://www.expedia.co.uk/Johnston-City-Hotels.d3000434357.Travel-Guide-Hotels) - [Kinmundy Hotels ](https://www.expedia.co.uk/Kinmundy-Hotels.d3000346365.Travel-Guide-Hotels) - [Macedonia Hotels ](https://www.expedia.co.uk/Macedonia-Hotels.d553248634983385273.Travel-Guide-Hotels) - [Mcleansboro Hotels ](https://www.expedia.co.uk/McLeansboro-Hotels.d3000346419.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Mount Vernon ](https://www.expedia.co.uk/Mount-Vernon-Hotels-Gay-Friendly-Hotel.0-0-d2463-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Mount Vernon Hotels ](https://www.expedia.co.uk/Mount-Vernon-Hotels.d2463.Travel-Guide-Hotels) - [Nashville Hotels ](https://www.expedia.co.uk/Nashville-Hotels.d180762.Travel-Guide-Hotels) - [Odin Hotels ](https://www.expedia.co.uk/Odin-Hotels.d3000346479.Travel-Guide-Hotels) - [Opdyke Hotels ](https://www.expedia.co.uk/Opdyke-Hotels.d3000346486.Travel-Guide-Hotels) - [Pinckneyville Hotels ](https://www.expedia.co.uk/Pinckneyville-Hotels.d6048035.Travel-Guide-Hotels) - [Rinard Hotels ](https://www.expedia.co.uk/Rinard-Hotels.d3000346537.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Salem ](https://www.expedia.co.uk/Salem-Hotels-Gay-Friendly-Hotel.0-0-d9890-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Salem Hotels ](https://www.expedia.co.uk/Salem-Hotels.d9890.Travel-Guide-Hotels) - [Sesser Hotels ](https://www.expedia.co.uk/Sesser-Hotels.d3000435307.Travel-Guide-Hotels) - [Sims Hotels ](https://www.expedia.co.uk/Sims-Hotels.d3000346582.Travel-Guide-Hotels) - [Pet-Friendly Hotels in Southwest Illinois ](https://www.expedia.co.uk/Southwest-Illinois-Hotels-Pet-Friendly-Hotel.0-0-d6058943-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Southwest Illinois Hotels ](https://www.expedia.co.uk/Southwest-Illinois-Hotels.d6058943.Travel-Guide-Hotels) - [Tamaroa Hotels ](https://www.expedia.co.uk/Tamaroa-Hotels.d3000346606.Travel-Guide-Hotels) - [Waltonville Hotels ](https://www.expedia.co.uk/Waltonville-Hotels.d3000346646.Travel-Guide-Hotels) - [West City Hotels ](https://www.expedia.co.uk/West-City-Hotels.d553248634983240590.Travel-Guide-Hotels) - [West Frankfort Hotels ](https://www.expedia.co.uk/West-Frankfort-Hotels.d55216.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Whittington ](https://www.expedia.co.uk/Whittington-Hotels-Gay-Friendly-Hotel.0-0-d56062-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Whittington ](https://www.expedia.co.uk/Whittington-Hotels-Pet-Friendly-Hotel.0-0-d56062-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Whittington Hotels ](https://www.expedia.co.uk/Whittington-Hotels.d56062.Travel-Guide-Hotels) - [Lodges in Whittington ](https://www.expedia.co.uk/Whittington-Lodges.d56062-aaLodges.Travel-Guide-Accommodation) - [Zeigler Hotels ](https://www.expedia.co.uk/Zeigler-Hotels.d3000346678.Travel-Guide-Hotels) - [Flights to Flora ](https://www.expedia.co.uk/Cheap-Flights-To-Flora.d178211.Travel-Guide-Flights) - [Flights to Galatia ](https://www.expedia.co.uk/Cheap-Flights-To-Galatia.d3000346275.Travel-Guide-Flights) - [Flights to Herrin ](https://www.expedia.co.uk/Cheap-Flights-To-Herrin.d183186.Travel-Guide-Flights) - [Flights to Mount Vernon ](https://www.expedia.co.uk/Cheap-Flights-To-Mount-Vernon.d2463.Travel-Guide-Flights) - [Flights to Odin ](https://www.expedia.co.uk/Cheap-Flights-To-Odin.d3000346479.Travel-Guide-Flights) - [Flights to Whittington ](https://www.expedia.co.uk/Cheap-Flights-To-Whittington.d56062.Travel-Guide-Flights) - [Flights from Herrin ](https://www.expedia.co.uk/lp/flights/183186/flights-from-herrin) - [Flights from Mount Vernon ](https://www.expedia.co.uk/lp/flights/2463/flights-from-mount-vernon) - [Flights from Christopher ](https://www.expedia.co.uk/lp/flights/3000346181/flights-from-christopher) - [Flights from Elkville ](https://www.expedia.co.uk/lp/flights/3000346241/flights-from-elkville) - [Flights from Kinmundy ](https://www.expedia.co.uk/lp/flights/3000346365/flights-from-kinmundy) - [Flights from Opdyke ](https://www.expedia.co.uk/lp/flights/3000346486/flights-from-opdyke) - [Flights from Sims ](https://www.expedia.co.uk/lp/flights/3000346582/flights-from-sims) - [Flights from Tamaroa ](https://www.expedia.co.uk/lp/flights/3000346606/flights-from-tamaroa) - [Flights from Waltonville ](https://www.expedia.co.uk/lp/flights/3000346646/flights-from-waltonville) - [Flights from Ewing ](https://www.expedia.co.uk/lp/flights/3000434034/flights-from-ewing) - [Flights from West Frankfort ](https://www.expedia.co.uk/lp/flights/55216/flights-from-west-frankfort) - [Flights from Mill Shoals ](https://www.expedia.co.uk/lp/flights/553248634983081197/flights-from-mill-shoals) - [Flights from Walnut Hill ](https://www.expedia.co.uk/lp/flights/553248634983204234/flights-from-walnut-hill) - [Flights from Bonnie ](https://www.expedia.co.uk/lp/flights/553248634983230566/flights-from-bonnie) - [Flights from Dahlgren ](https://www.expedia.co.uk/lp/flights/553248634983269993/flights-from-dahlgren) - [Flights from Macedonia ](https://www.expedia.co.uk/lp/flights/553248634983385273/flights-from-macedonia) - [Flights from Jeffersonville ](https://www.expedia.co.uk/lp/flights/553248634983535313/flights-from-jeffersonville) - [Flights from Jefferson County ](https://www.expedia.co.uk/lp/flights/553248635976430318/flights-from-jefferson-county) - [Flights from Benton ](https://www.expedia.co.uk/lp/flights/6866/flights-from-benton) - [Flights from Du Quoin ](https://www.expedia.co.uk/lp/flights/98092/flights-from-du-quoin) - [Flora Holidays ](https://www.expedia.co.uk/Flora.d178211.Holidays-City-Breaks) - [Visit McLeansboro ](https://www.expedia.co.uk/McLeansboro.dx3000346419) - [Visit Mount Vernon ](https://www.expedia.co.uk/Mount-Vernon.dx2463) - [Pheasant Hollow Winery ](https://www.expedia.co.uk/Pheasant-Hollow-Winery-Whittington.d6312899.Attraction) - [William Jennings Bryan Boyhood Home and Museum ](https://www.expedia.co.uk/William-Jennings-Bryan-Boyhood-Home-And-Museum-Salem.d6187105.Attraction) - [Car hire Alton ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Alton.d6108.Car-Hire-Guide) - [Car hire Assumption ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Assumption.d3000346104.Car-Hire-Guide) - [Car hire Ava ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Ava.d3000420830.Car-Hire-Guide) - [Rental cars Decatur airport ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Decatur.d6027335.Car-Hire-Guide) - [Car hire Effingham ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Effingham.d7822.Car-Hire-Guide) - [Car hire Granite City ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Granite-City.d8015.Car-Hire-Guide) - [Car hire Grayville ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Grayville.d6139856.Car-Hire-Guide) - [Car hire Hartford ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Hartford.d6286985.Car-Hire-Guide) - [Car hire Lawrenceville ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Lawrenceville.d8617.Car-Hire-Guide) - [Car hire Litchfield ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Litchfield.d6059222.Car-Hire-Guide) - [Car hire Mattoon ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Mattoon.d2443.Car-Hire-Guide) - [Rental cars MidAmerica-St. Louis airport ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-MidAmerica-St-Louis.d6034496.Car-Hire-Guide) - [Car hire Noble ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Noble.d3000346472.Car-Hire-Guide) - [Car hire Paris ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Paris.d143485.Car-Hire-Guide) - [Car hire Raleigh ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Raleigh.d553248634983372429.Car-Hire-Guide) - [Car hire Redmon ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Redmon.d3000346534.Car-Hire-Guide) - [Car hire Springfield ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Springfield.d3249.Car-Hire-Guide) - [Car hire Swansea ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Swansea.d164131.Car-Hire-Guide) - [Car hire Whittington ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Whittington.d56062.Car-Hire-Guide) - [Enterprise Rental Cars in Southwest Illinois ](https://www.expedia.co.uk/Enterprise-Car-Rentals-In-Southwest-Illinois.d6058943-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Southwest Illinois ](https://www.expedia.co.uk/Hertz-Car-Rentals-In-Southwest-Illinois.d6058943-c40.Car-Rental-Guide-Suppliers) - [People Carrier Car Hire in Flora ](https://www.expedia.co.uk/Van-Car-Rentals-In-Flora.d178211-tVan.Car-Rental-Guide-Class) - [Dix Holiday Rentals ](https://www.expedia.co.uk/Dix-Holiday-Rentals.d6023670.Travel-Guide-HolidayRentals) - [Enfield Holiday Rentals ](https://www.expedia.co.uk/Enfield-Holiday-Rentals.d3000433975.Travel-Guide-HolidayRentals) - [Flora Holiday Rentals ](https://www.expedia.co.uk/Flora-Holiday-Rentals.d178211.Travel-Guide-HolidayRentals) - [Nashville Holiday Rentals ](https://www.expedia.co.uk/Nashville-Holiday-Rentals.d180762.Travel-Guide-HolidayRentals) - [Odin Holiday Rentals ](https://www.expedia.co.uk/Odin-Holiday-Rentals.d3000346479.Travel-Guide-HolidayRentals) - [Sims Holiday Rentals ](https://www.expedia.co.uk/Sims-Holiday-Rentals.d3000346582.Travel-Guide-HolidayRentals) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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