Title: TOP Southern Illinois Spa Hotels for 2026 - Spas in Southern Illinois, IL | Expedia.co.uk [Southern Illinois Travel Guide](https://expedia.co.uk/Southern-Illinois.dx6233859)[Hotels in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)[Holiday Rentals in Southern Illinois](https://expedia.co.uk/Southern-Illinois-Holiday-Rentals.d6233859.Travel-Guide-HolidayRentals)[Flights to Southern Illinois](https://expedia.co.uk/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)[Southern Illinois Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Southern-Illinois.d6233859.Car-Hire-Guide)[Southern Illinois Holidays](https://expedia.co.uk/Southern-Illinois.d6233859.Holidays-City-Breaks) ![Southern Illinois featuring landscape views, a sunset and forest scenes](https://images.trvl-media.com/place/553248635944113522/0e29d2f8-2d58-457a-908d-4b89b13776d9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Southernmost Illinois Tourism Bureau # Find Spa Hotels in Southern Illinois, IL - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Illinois Spa Hotels Tonight [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-01-11&endDate=2026-01-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-01-12&endDate=2026-01-13&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-01-16&endDate=2026-01-18&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6233859&startDate=2026-01-23&endDate=2026-01-25&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southern Illinois hotels with a spa ![Sauna, hot tub, body treatments, hot stone massages](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/8fcd4708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/84958281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/3a123ac6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/98000000/97070000/97064800/97064786/a0fca68c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Walker's Bluff Casino Resort [](https://www.expedia.co.uk/Carterville-Hotels-Walkers-Bluff-Casino-Resort.h97064786.Hotel-Information) Carterville 9.4/10 Exceptional (397 reviews) "Clean & friendly place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beverly £95 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Carterville-Hotels-Walkers-Bluff-Casino-Resort.h97064786.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast ](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/5fa70c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom (Feature) | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/40930878.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) Cape Girardeau 9.4/10 Exceptional (1,003 reviews) "Breakfast was very good and staff was extremely friendly and rooms were very clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rex £80 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11750000/11746100/11746044/c57795eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed (Room 6, Washington House) | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/12000000/11750000/11746100/11746044/4fe7dd35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/12000000/11750000/11746100/11746044/1616fd88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast (USD 17.76 per person)](https://images.trvl-media.com/lodging/12000000/11750000/11746100/11746044/ac8537d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 1895 Washington Hotel [](https://www.expedia.co.uk/Paducah-Hotels-1895-Washington-Hotel.h11746044.Hotel-Information) Paducah 9.2/10 Wonderful (401 reviews) "Friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David [](https://www.expedia.co.uk/Paducah-Hotels-1895-Washington-Hotel.h11746044.Hotel-Information) ![Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/f78a36b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/w2880h1936x0y0-34b8c827.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![6 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/d825c5c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/4519749c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ameristar Casino Resort and Spa [](https://www.expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) St. Charles 8.4/10 Very good (1,006 reviews) "Was an amazing hotel to stay at!! Clean spacious and very nice!!! Will stay here again!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darci £153 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/11000000/10240000/10239000/10238981/bb763620.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/11000000/10240000/10239000/10238981/19778331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![43-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/11000000/10240000/10239000/10238981/b1c233a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![43-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/11000000/10240000/10239000/10238981/141990fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arthur's Country Inn [](https://www.expedia.co.uk/Champaign-Hotels-Arthurs-Country-Inn.h10238981.Hotel-Information) Arthur 8.4/10 Very good (133 reviews) "The staff were wonderful! We got in late, and they had everything set for us to self check-in. The room was clean and updated. It is in a small town with great Amish food. Very safe and affordable. Would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle £84 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Champaign-Hotels-Arthurs-Country-Inn.h10238981.Hotel-Information) ![Massages](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/1c63195a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bd7064dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/15dd97ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bedc886c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21C Museum Hotel St Louis [](https://www.expedia.co.uk/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) Downtown West 9.0/10 Wonderful (1,541 reviews) "Great atmosphere and amenities." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shane £129 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![Couples treatment room(s), hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/56a41562.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, 1 King Bed, Non Smoking | Living area | 42-inch plasma TV with cable channels, TV, DVD player](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/3714f01f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), hot tub, body treatments, aromatherapy](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/941b0ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop bar](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/5b370fff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel St Louis [](https://www.expedia.co.uk/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) Downtown St. Louis 9.4/10 Exceptional (1,003 reviews) "Great service, great staff , room service food really good,, great view of the arch and the river. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £362 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) ![Body treatments, aromatherapy, hot stone massages, deep-tissue massages](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/b7162ce8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/a54897ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/3f20ce75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/1817cdae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ritz-Carlton, St. Louis [](https://www.expedia.co.uk/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information) Clayton 9.2/10 Wonderful (555 reviews) "Great property. Concierge level wonderful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mike £435 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-25&endDate=2026-01-26®ionId=6233859&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Southern Illinois ### Top Southern Illinois attractions for a relaxing vacation Southern Illinois is a paradise for travellers seeking a blend of relaxation and adventure, particularly for those who appreciate spa accommodations. Begin your journey in the stunning Shawnee National Forest, where you can unwind amidst the lush greenery, with opportunities for hiking, rock climbing, and horseback riding. After a day outdoors, indulge in rejuvenating treatments at nearby spa hotels that offer serene views of the forest. Take a leisurely stroll through the charming town of Carbondale, where you can explore local boutiques and cafes, then retreat to your hotel for a soothing massage or wellness programme. The renowned Giant City State Park provides a perfect backdrop for both relaxation and exploration, featuring unique sandstone cliffs and trails, along with picnic areas ideal for families. For a unique experience, consider a stay at a vineyard or winery in the region, where you can enjoy wine tasting and vineyard tours, followed by a tranquil evening soaking in the spa’s facilities. When you choose to stay in the heart of these experiences, you’ll find attentive service and top hotels that cater to high expectations, making your Southern Illinois getaway memorable. ## Top Southern Illinois Hotel Reviews ![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/f9296f7b_y.jpg) ### Drury Plaza Hotel Mt. Vernon 10/10 Excellent "Room was very clean, staff is very friendly and the food and drinks amenities were really nice." [](https://expedia.co.uk/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information) ![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/c56c0460_y.jpg) ### Drury Inn & Suites St. Louis Fairview Heights 10/10 Excellent "Romello had a great spirit and awesome customer service !! " [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information) ![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/d2bc121f_y.jpg) ### Drury Inn & Suites St. Louis O'Fallon, IL 10/10 Excellent "Good service. Clean facility " [](https://expedia.co.uk/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information) ![Holiday Inn Express Metropolis by IHG](https://images.trvl-media.com/lodging/1000000/220000/211900/211819/0b536094_y.jpg) ### Holiday Inn Express Metropolis by IHG 10/10 Excellent "We were there for two nights. The place was clean and the staff was great." [](https://expedia.co.uk/Metropolis-Hotels-Holiday-Inn-Express-Metropolis.h211819.Hotel-Information) ![Drury Inn & Suites Marion](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/a8315e37_y.jpg) ### Drury Inn & Suites Marion 10/10 Excellent "Clean room, and quiet. Nice location with restaurants close by." [](https://expedia.co.uk/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information) ![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/b34f836a_y.jpg) ### Comfort Suites Mount Vernon 10/10 Excellent "Everything was great. Second time staying there." [](https://expedia.co.uk/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information) ![Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City](https://images.trvl-media.com/lodging/10000000/9320000/9312600/9312525/95ce096c_y.jpg) ### Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City 10/10 Excellent "Nice quiet atmosphere with outstanding staff. 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