A forested valley with autumn foliage, a rocky cliff, and a sunset.

Search Hotels by Best Western in Southern Illinois from £68

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
13 Oct - 14 Oct
Tomorrow
14 Oct - 15 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Southern Illinois Best Western

A modern living room with a sofa, chairs, a coffee station, and a dining area.
A hotel room with a large bed, a bedside table, a lamp, and a wall-mounted light fixture.
A reception desk with a blue accent wall, a framed welcome sign, and a flat-screen TV above it.
A modern kitchen with a central island, bar stools, and pendant lighting.

1. Best Western St. Louis Fairview Heights

Best Western St. Louis Fairview Heights
Fairview Heights
United States
LaShelle
£68
includes taxes & fees
1 Nov - 2 Nov
Best Western St. Louis Fairview Heights
A self-service breakfast area with a coffee machine, refrigerated display case, and various food items.
A gym with treadmills, ellipticals, and weight machines.
A Best Western hotel with a parking lot and a covered entrance.
A hotel room with a bed, a television, a desk, a coffee machine, and a bathroom visible through an open door.

2. Best Western Marion Hotel

Best Western Marion Hotel
Marion
United States
Cornell
£69
includes taxes & fees
25 Oct - 26 Oct
Best Western Marion Hotel
An indoor swimming pool with a clear view of the surrounding area, including a seating area with chairs and a view of the outdoors through large windows.
A hotel room with a large bed, two bedside tables with lamps, a desk with a chair, a television, and a framed artwork on the wall.
A Best Western hotel with a modern facade, a parking lot, and a clear sky.
A hotel room with a desk, two monitors, a keyboard, and a mouse.

3. Best Western Delta Inn

Best Western Delta Inn
Effingham
United States
Susan
£69
includes taxes & fees
18 Oct - 19 Oct
Best Western Delta Inn
A hotel lobby with a dining area, kitchen, and seating.
An outdoor patio with a table and chairs, a white fence, and a building with large windows.
A modern lobby with a reception desk, seating area, and a large flat-screen TV mounted on the wall.
A hotel room with a large bed, a desk, a chair, a TV, and a nightstand with a lamp.

4. Best Western Heartland Inn

Best Western Heartland Inn
Mattoon
United States
Mike
£76
includes taxes & fees
1 Nov - 2 Nov
Best Western Heartland Inn
An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows offering views of the outside.
A gym with treadmills, ellipticals, and weight machines.
A hotel room with a bed, a desk, a chair, and a small table.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

5. Spark by Hilton Troy

Spark by Hilton Troy
Troy
United States
Matthew
Spark by Hilton Troy
A hotel room with two beds, a desk, a chair, a TV, a lamp, and a painting on the wall.
A modern restaurant with a bar area, multiple tables and chairs, and a kitchen in the background.
A modern hotel lobby with leather sofas, a flat-screen TV, and framed artwork on the walls.
A bar area with multiple stools, a bar counter, shelves of liquor bottles, and hanging pendant lights.

6. Best Western Saluki Inn

Best Western Saluki Inn
Carbondale
United States
Bryan
£79
includes taxes & fees
8 Nov - 9 Nov
Best Western Saluki Inn
A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.
A Best Western U.S. Inn with a modern design, featuring a covered entrance and a parking lot.
A hotel room with two beds, a desk, and a window with a view.
A reception area with a stone wall, a round mirror, a reception desk, and a computer setup.

7. Best Western U. S. Inn

Best Western U. S. Inn
Nashville
United States
Steven
£99
includes taxes & fees
14 Oct - 15 Oct
Best Western U. S. Inn
A hotel room with a large bed, a desk, a chair, a TV, and a sofa.
A modern hotel lobby with a brown sofa, a globe on a wooden stand, and a framed abstract painting on the wall.
A breakfast buffet setup with a microwave, glass display cases, and various food items.
A Best Western hotel with a large sign, a parking lot, and a FedEx package on the ground.

8. Best Western Flora Inn

Best Western Flora Inn
Flora
United States
Terri
£74
includes taxes & fees
19 Oct - 20 Oct
Best Western Flora Inn
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"All good"
Derek 2-night trip
Posted 1 hour ago
Drury Plaza Hotel Mt. Vernon
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent
"Excellent place to stay. Convenient to eating and shopping. We will be back!"
Jeffrey 1-night trip
Posted 1 hour ago
Drury Inn & Suites St. Louis O'Fallon, IL
Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"Greta stay with great staff who made our trip home with 3 littles all that much easier."
Brett 1-night trip
Posted 4 hours ago
Drury Inn & Suites Marion
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"I've stayed at this particular Drury a couple of times now and am most impressed with the staff. My only complaint was that we were to late for the nightly drinks and treats that you have for the guests..."
Dean 1-night trip
Posted 17 hours ago
Drury Inn & Suites St. Louis Fairview Heights
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

8/10 Good
"Good place to park your head"
Sheri 1-night trip
Posted 20 hours ago
Baymont by Wyndham Effingham
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

8/10 Good
"This hotel is always a convenient choice and is well run. Staff are always helpful. I always love that I see the STL arch from the parking lot! I do hope the property is scheduled for some carpeting upgrades soon. The elevator was is need of a refresh and I was surprised to see a rip in the carpet of my otherwise suitable room."
Jill 2-night trip
Posted 1 day ago
Comfort Inn Edwardsville - St. Louis
Best Western Marion Hotel

Best Western Marion Hotel

8/10 Good
"The room was clean and the bed was comfortable. The breakfast was nice, but lacked orange juice. The staff was friendly and very helpful."
Rick 2-night trip
Posted 2 days ago
Best Western Marion Hotel
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent
"Location made this a wonderful stay. Also the hotel smelled nice and clean."
Laura 3-night trip
Posted 3 days ago
Country Inn & Suites by Radisson, Marion, IL

Explore a world of travel with Expedia