South San Diego Holidays from £929

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Your South San Diego Holiday

Leave all the planning to us with a South San Diego holiday package. With everything arranged before you jet off, all you'll have to do is relax and enjoy this destination's wonders to the fullest. A trip to South San Diego wouldn't be complete without spending a day or two in Chula Vista. This city is among the leading places to visit here. From the moment you book your South San Diego holiday to when you get back home, Expedia will be with you every step of the way.

Top South San Diego Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
The Dextro Hotel, BW Premier Collection

The Dextro Hotel, BW Premier Collection

3 out of 5
Downtown San Diego
per person
16 Oct - 20 Oct
found 16 hours ago
Return direct flight included
London (LON) to San Diego (SAN)
7.6/10 Good! (1,006 reviews)
Hotel was wonderful, beds were comfortable could use some new pillows. The staff were great very accommodating on whatever you needed.

Reviewed on 29 Jul 2025

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Save 100% on your flight
per person
16 Oct - 20 Oct
found 16 hours ago
Return direct flight included
London (LON) to San Diego (SAN)
8.4/10 Very Good! (1,488 reviews)
I reserved a room with 2 beds for my sister and I for a one night stay at Sophia hotel. When we arrived at 4PM our room was not ready and Ian gave me two waters and two chocolate candy bars and offered two rooms with one bed in place of the one room with two beds on the newly renovated floor right next to each other at no extra charge. It worked out perfectly as we had our own space.

Reviewed on 25 Jul 2025

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4 out of 5
Downtown San Diego
Save 100% on your flight
per person
17 Sept - 24 Sept
found 6 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
9/10 Wonderful! (936 reviews)
Property is great for walking. Great to go to Petco Park.

Reviewed on 23 Jul 2025

InterContinental San Diego by IHG

InterContinental San Diego by IHG

4 out of 5
Downtown San Diego
Save 100% on your flight
per person
17 Sept - 24 Sept
found 6 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
9/10 Wonderful! (1,004 reviews)
Breakfast was good. Nice location. Weird smell after housekeeping. Didn’t inform me when I let my cloth in the room after checkout

Reviewed on 28 Jul 2025

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

3 out of 5
Downtown San Diego
per person
16 Oct - 20 Oct
found 16 hours ago
Return direct flight included
London (LON) to San Diego (SAN)
9.2/10 Wonderful! (166 reviews)
Overall, my stay at the Sentral was great. Location was key since I was attending Comic Con so walking back and forth took minutes. Great places to eat around the area and only a couple blocks from the gaslamp district. Felt secure and well taken care there especially late at night coming back to my room. Only complaint would be the entrance door and bathroom door of my room where it took some effort to close and open while the bathroom door was very noisy opening and closing. Besides that, would recommend others to stay and would come back myself as well.

Reviewed on 25 Jul 2025

Where to stay in South San Diego

Find the best South San Diego areas and neighborhoods for the activities you enjoy most. Learn more about South San Diego
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Otay Mesa West

Even though there aren't top sights in Otay Mesa West, you can explore the larger area and take in top sights like San Ysidro Border Crossing. Jump on the metro at Iris Avenue Trolley Station to see more of the city.

Find hotels in Otay Mesa West

South San Diego Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Diego Intl. Airport (SAN)

Top hotels in South San Diego

Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center

4 out of 5
1000 H Street, Chula Vista, CA
Fully refundableReserve now, pay when you stay
The price is £298 per night from 28 Aug to 29 Aug
£298
28 Aug - 29 Aug
includes taxes & fees
7.8/10 Good! (52 reviews)
"Great property, but terrible location. The only negative about the resort is the Immediate Surrounding neighborhood is unsafe. As a Family you do not feel safe walking around. Must stay on property or drive 20 minutes to get in a better location."

Reviewed on 27 Jul 2025

Gaylord Pacific Resort & Convention Center
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2.5 out of 5
2296 Niels Bohr Ct, San Diego, CA
Fully refundable
The price is £111 per night from 4 Aug to 5 Aug
£111
4 Aug - 5 Aug
includes taxes & fees
7.8/10 Good! (1,424 reviews)
"Every thing great"

Reviewed on 28 Jul 2025

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
The price is £94 per night from 10 Aug to 11 Aug
£94
10 Aug - 11 Aug
includes taxes & fees
8/10 Very Good! (1,918 reviews)
Exceptional Staff / Front Desk Experience
"This hotel experience was exceptional because of the staff (thanks Pamela!) and care they took to ensure our stay was the best possible. I was there for Comic-Con and through the chaos we had a shuttle that ran every 15-20 minutes, a room with comfortable pillows and a view of the pool, reasonable ..."

Reviewed on 27 Jul 2025

Handlery Hotel
See all 7,561 properties in South San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
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Family Friendly Holidays

What to do in South San Diego

LEGOLAND® California Resort

LEGOLAND® California Resort

£58
per adult
82% of travellers recommend
LEGOLAND® California Resort
San Diego City Lights Night Tour

San Diego City Lights Night Tour

£34
per adult
96% of travellers recommend
San Diego City Lights Night Tour
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

£91
per adult
86% of travellers recommend
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
See all activities in South San Diego

Frequently asked questions

How much does a South San Diego travel package cost?
Create unforgettable memories with our South San Diego travel packages, which start from a low £929. Pick the hotels and flights that match your travel style. Then, add on a couple of enriching experiences for an amazing adventure.
If I'm not able to travel, can I cancel my South San Diego travel package?
Your situation can change in a flash, so yes. You may be able to cancel or change your South San Diego travel package for free within 24 hours of booking. For bookings older than that, you can still cancel and rebook, but your car rental company, hotel or airline may charge additional fees. Want more information? Visit our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.
How do I get a cheap travel package to South San Diego?
Booking a South San Diego holiday package with Expedia is one of the easiest ways to save. We offer access to over 550 airlines and 1,000,000 hotel options around the globe. With such a fantastic range to select from, you'll have no issues pulling together your next dream adventure.
Does Expedia offer Book Now, Pay Later South San Diego holidays?
Expedia has joined forces with online lender Klarna to make booking your next break easier on your bank balance. Paying by instalment means you can spread the costs of your dream holiday, leaving you with more money to spend while you're travelling. Klarna has several payment plans to pick from, so you're sure to find something that suits your budget. Consider these flexible payment options:

  • Pay monthly holidays: Klarna offers convenient monthly payment plans that suit all types of budgets, so you can book that well-earned holiday now.
  • Pay in instalments holidays: Like the idea of paying down your holiday in multiple transactions? Then select this Book Now, Pay Later option from Klarna.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than all of it upfront) makes it easier to click that "book now" button, consider a low deposit holiday payment plan from Klarna.

How far in advance should I book my South San Diego holiday?
The earlier, the better. Airlines usually advertise flights around a year prior to departure, and this is your chance to score some of the lowest prices. Boss just told you to use up some holiday time next month? That's alright! Expedia are never short on fantastic bargains to send you off on the getaway of your dreams, at a price you can afford.
What does an Expedia South San Diego travel package include?
Flights, rental cars and hotels, or any combination of them — it's your pick! Whether you're headed to South San Diego with the family or adventuring with your friends, there's a bundle to suit every budget and style. Once you've made your booking, why not add on some tours or activities?
What should I know before booking a South San Diego travel package?
We already have low prices. However, you'll score an even better deal when you book your hotels, flights and car rentals together. With an Expedia package, you'll get transparent pricing and lots of choice.
Can I choose my airline with a South San Diego Expedia travel package?
Expedia has access to more than 550 airline partners worldwide, so you certainly can. Just select the carrier that suits you and create your ideal South San Diego escape.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.