South San Diego Holidays from £875

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Your South San Diego Holiday

Leave all the planning to us with a South San Diego holiday package. With everything arranged before you jet off, all you'll have to do is relax and enjoy this destination's wonders to the fullest. A trip to South San Diego wouldn't be complete without spending a day or two in Chula Vista. This city is among the leading places to visit here. From the moment you book your South San Diego holiday to when you get back home, Expedia will be with you every step of the way.

Top South San Diego Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hyatt Vacation Club at The Welk, San Diego Area

Hyatt Vacation Club at The Welk, San Diego Area

3.5 out of 5
Lawrence Welk Resort Village
Price was £1,009, price is now £875 per person
£875
per person
9 May - 13 May
found 20 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
8.4/10 Very Good! (1,649 reviews)
Enjoyed the pool and jacuzzi.

Reviewed on 13 Mar 2026

The Sofia Hotel

The Sofia Hotel

3.5 out of 5
Downtown San Diego
Price was £1,165, price is now £877 per person
£877
per person
9 May - 13 May
found 20 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
8.6/10 Excellent! (1,818 reviews)
Perfect trip - thank you

Reviewed on 14 Mar 2026

The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
Mission Bay
Price was £1,100, price is now £977 per person
£977
per person
9 May - 13 May
found 20 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
9/10 Wonderful! (4,134 reviews)
The infinity pool is beautiful. We loved the pool and hot tub area. The staff are all very nice and helpful. Our room was nice and very clean. My only criticism is that the room is in need of a refurbish. The shower head was not great. Wish there was a handheld in shower would have been better. Our shower head didn’t work well. The cabinetry in the room is old so looks tired but it’s a great hotel regardless. I recommend it regardless of the need for some upgrades in the room.

Reviewed on 14 Mar 2026

Handlery Hotel

Handlery Hotel

3.5 out of 5
Mission Valley
Price was £978, price is now £900 per person
£900
per person
9 May - 13 May
found 20 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
8.2/10 Very Good! (2,326 reviews)
Excellent experience

Reviewed on 15 Mar 2026

Sycuan Casino Resort

Sycuan Casino Resort

4 out of 5
Price was £1,073, price is now £1,000 per person
£1,000
per person
9 May - 13 May
found 20 hours ago
Return direct flight included
Manchester (MAN) to San Diego (SAN)
9.2/10 Wonderful! (1,768 reviews)
Clean and comfortable beds

Reviewed on 14 Mar 2026

The Annual Holiday Sale

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Where to stay in South San Diego

Find the best South San Diego areas and neighborhoods for the activities you enjoy most. Learn more about South San Diego
Default Image

Otay Mesa West

Even though there aren't top sights in Otay Mesa West, you can explore the larger area and take in top sights like San Ysidro Border Crossing. Jump on the metro at Iris Avenue Trolley Station to see more of the city.

Find hotels in Otay Mesa West

South San Diego Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Diego Intl. Airport (SAN)

Top hotels in South San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is £213 per night from 5 Apr to 6 Apr
£213
5 Apr - 6 Apr
includes taxes & fees
8.8/10 Excellent! (2,452 reviews)
The room was clean but mixed with some things new and other things old. Never had hot water for the shower however the shower was large. Our view was awesome loved watching all the sailboats, skiers, row boats, kayaks etc. We even seen a purpose. People with dogs let them poo without picking up not ...

Reviewed on 12 Mar 2026

Paradise Point Resort & Spa
Best Western Seven Seas

Best Western Seven Seas

3 out of 5
411 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is £63 per night from 1 Apr to 2 Apr
£63
1 Apr - 2 Apr
includes taxes & fees
7.8/10 Good! (3,287 reviews)
When checking in on Thursday I asked for a late checkout on Saturday because I work Saturday morning and fly home that afternoon. Checkout was 11am. I get off work at 11am and work 10 minutes from this hotel. The person said to ask the morning of departure. Because I leave for work Saturday morning ...

Reviewed on 14 Mar 2026

Best Western Seven Seas
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is £187 per night from 5 Apr to 6 Apr
£187
5 Apr - 6 Apr
includes taxes & fees
9/10 Wonderful! (3,418 reviews)
Perfect location for a fun time.

Reviewed on 14 Mar 2026

Hard Rock Hotel San Diego
See all 7,752 properties in South San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
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Family Friendly Holidays

What to do in South San Diego

San Diego Premier Bottomless Mimosa Brunch Cruise

City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise

£59
per adult
90% of travellers recommend
City Cruises San Diego: Premier Bottomless Mimosa Brunch Cruise
San Diego Whale Watching Tour

San Diego Whale Watching & Dolphin Cruise

£53
per adult
88% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
San Diego: Museum of Illusions Entry Ticket

San Diego: Museum of Illusions Entry Ticket

£26
per adult
84% of travellers recommend
San Diego: Museum of Illusions Entry Ticket
See all activities in South San Diego

Frequently asked questions

Can I cancel my flight booking to South San Diego due to COVID-19?
If you haven't booked yet, go over the terms and conditions of the airfare you're considering. If you've already secured your flight to South San Diego, visit our Customer Service Portal. It has information that will help determine which COVID-19 policies apply to your reservation and provide you with the next steps.
What's the best way to find cheap flights to South San Diego that have flexible change policies?
By using our helpful "No change fee" filter, that's how. Just type in your travel details, click the "Search" button, then tick the checkbox directly underneath the "Flexible change policies" subheading (it's on the left). Expedia makes it a cinch to find cheap, flexible tickets to South San Diego.
What are some of the general tips for travellers to South San Diego during the COVID-19 outbreak?
If it's your first time travelling during COVID-19, you'll notice a few more regulations and rules in place. Follow these tips and make your escape to South San Diego a smooth one:
  • Research what, if any, rules or restrictions apply to both your origin and destination. It may not be possible to travel depending on local circumstances, so make sure you check before you lock in your flight.
  • You're required to wear a face mask throughout your travel experience, even at screening checkpoints. You should be prepared to lower your mask for ID purposes when asked.
  • You're no longer required to hand your boarding pass (paper or electronic) directly to a TSA officer. Rather, position the pass on the reader and then hold it up so the agent can inspect it.
  • TSA is now allowing passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on luggage. This will need to be removed from your bag for X-ray screening.
  • Put any personal items (phone, wallet and keys) in your carry-on rather than a bin to reduce handling during the screening process.
  • If you're taking food on the plane, place it in a clear plastic bag and then into a scanning bin. This reduces the likelihood that a TSA officer will need to touch your food container or carry-on bag for closer inspection.

Which airlines fly to South San Diego?
American Airlines is a top carrier servicing South San Diego. Search for airfares to San Diego Intl. Airport (SAN) and you'll have 759 American Airlines flights every month to pick from.
How can I find cheap tickets to South San Diego?
One of the best ways to snare cheap tickets to South San Diego is to be flexible with your travel dates. Search for your flights, then click "flexible dates" above the results. You'll see the cheapest prices for nearby days. The lowest price for a flight to South San Diego in the last seven days was . Booking ahead will usually help you get an even bigger bargain.
How much is a flight to South San Diego?
You could have snapped up a return air ticket to South San Diego from anywhere between and in the last seven days. For one-way journeys from (), the lowest price during this period was just .
What are the most popular airports to fly into in South San Diego?
Start organising your South San Diego escape by booking a ticket on one of the 6709 monthly flights to San Diego Intl. Airport (SAN). This is the region's main point of entry.
When is the cheapest time to fly to South San Diego?
If you'd rather spend your holiday cash exploring South San Diego rather than on your journey there, jet off earlier in the week. The most affordable day to fly is normally Tuesday, with Monday close behind. With many people travelling over the weekend, Saturday typically has the costliest fares.
How much is a plane ticket to South San Diego?
In the last seven days, plane tickets to South San Diego varied between and . Prices generally depend on the departure time, seating class, airline and when the fare is booked.
Which airlines with flights to South San Diego employ COVID-19 cleanliness policies?
While travelling during the COVID-19 pandemic can be challenging, airlines are doing their utmost to protect the well-being of customers and crew. Here are a few carriers that have implemented changes:
  • Southwest Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Alaska Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.