Title: Cheap Car Hire in South San Diego, USA - Expedia.co.uk [South San Diego Travel Guide](https://expedia.co.uk/South-San-Diego.dx553248632063518562)[Hotels in South San Diego](https://expedia.co.uk/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[Flights to South San Diego](https://expedia.co.uk/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[Things to do in South San Diego](https://expedia.co.uk/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)[South San Diego Holidays](https://expedia.co.uk/South-San-Diego.d553248632063518562.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/177683/0b5e1cb4-4da2-49b0-8686-3e02eb9d5303.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Car Rentals in South San Diego, USA ## Search and Compare from Car Companies in South San Diego Photo by Elizabeth Bagnas ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXUK-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Top Rental Car Deals in South San Diego \* Price found within the past 6 days. Click for updated prices. Tue, 16 Dec - Wed, 17 Dec ### Economy Hyundai Venue or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 2745 Otay Pacific Dr, Ste #6, Cross Border Xpress Cbx, San Diego, California 92154, USA 4.1 mi from South San Diego city centre ![Hyundai Venue](//mediaim.expedia.com/cars/41/8790b76e-3028-4f1e-b3ff-9c11cf788d03.jpg) #### £77 total found 13 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=32.548230&olon=-116.974830&date1=16/12/2025&date2=17/12/2025&pprfrr=null&tprfrr=77.2&cvrfrr=ZI&ctrfrr=EC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22economy%22]) Tue, 16 Dec - Wed, 17 Dec ### Full Size Toyota Camry or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 2745 Otay Pacific Dr, Ste #6, Cross Border Xpress Cbx, San Diego, California 92154, USA 4.1 mi from South San Diego city centre ![Toyota Camry](//mediaim.expedia.com/cars/41/f8359e2f-1f3f-4c65-ac4c-bc85e53c01f5.jpg) #### £115 total found 13 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=32.548230&olon=-116.974830&date1=16/12/2025&date2=17/12/2025&pprfrr=null&tprfrr=115.2&cvrfrr=ZI&ctrfrr=FC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22fullsize%22]) Tue, 16 Dec - Wed, 17 Dec ### Standard Volkswagen Jetta or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 2745 Otay Pacific Dr, Ste #6, Cross Border Xpress Cbx, San Diego, California 92154, USA 4.1 mi from South San Diego city centre ![Volkswagen Jetta](//mediaim.expedia.com/cars/41/518390a3-aa30-4ee4-9bb5-1243de3d0866.jpg) #### £115 total found 13 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=32.548230&olon=-116.974830&date1=16/12/2025&date2=17/12/2025&pprfrr=null&tprfrr=115.2&cvrfrr=ZI&ctrfrr=SC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22standard%22]) Tue, 16 Dec - Wed, 17 Dec ### Compact Kia Soul or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 2745 Otay Pacific Dr, Ste #6, Cross Border Xpress Cbx, San Diego, California 92154, USA 4.1 mi from South San Diego city centre ![Kia Soul](//mediaim.expedia.com/cars/41/e7c1fd21-3564-4890-a4ed-2f7ca59d757f.jpg) #### £135 total found 13 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=32.548230&olon=-116.974830&date1=16/12/2025&date2=17/12/2025&pprfrr=null&tprfrr=135.4&cvrfrr=ZI&ctrfrr=CC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22compact%22]) Tue, 16 Dec - Wed, 17 Dec ### Midsize Toyota Corolla or similar - 5 people - Unlimited mileage ![Avis](//mediaim.expedia.com/cars/logos/ZI.png) #### Pick-up location 2745 Otay Pacific Dr, Ste #6, Cross Border Xpress Cbx, San Diego, California 92154, USA 4.1 mi from South San Diego city centre ![Toyota Corolla](//mediaim.expedia.com/cars/41/724f6f6b-c451-44b5-b34e-8d67280e16eb.jpg) #### £134 total found 13 hours ago [](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&olat=32.548230&olon=-116.974830&date1=16/12/2025&date2=17/12/2025&pprfrr=null&tprfrr=134.5&cvrfrr=ZI&ctrfrr=IC&crfrr=pricefeedResponseFlex&SearchType=Place&selCC=[%22midsize%22]) ### Don't see what you're looking for? See all car hire in South San Diego [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=South%20San%20Diego,%20California,%20United%20States%20of%20America&dpln=553248632063518562&date1=21/12/2025&date2=23/12/2025&crfrr=defaultFlex&SearchType=Place) Lowest prices found within the past 13 hours. Prices and availability subject to change. Additional terms may apply. ## Frequently asked questions ### What happens if I need to cancel my South San Diego car reservation? ### What types of cars can I rent in South San Diego? ### How do I find the best car hire deals in South San Diego with Expedia? ### How old do you have to be to rent a car in South San Diego? ### What do you need to rent a car in South San Diego? ### Can I hire a car for a month or longer in South San Diego? ### Where can I find a South San Diego hire car if I am younger than 25? ### Why should I rent a South San Diego car with Expedia? ## Car Hire Information | Popular car types: | [SUV](https://www.expedia.co.uk/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.co.uk/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.co.uk/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | £77 | | Our second best deal of the day: | £115 | | Our third best deal of the day: | £134 | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [Hotels near Atlantis Laser Tag ](https://www.expedia.co.uk/Atlantis-Laser-Tag-Hotels.0-l553248621532638600-0.Travel-Guide-Filter-Hotels) - [Bonita Hotels ](https://www.expedia.co.uk/Bonita-Hotels.d177687.Travel-Guide-Hotels) - [Hotels near Brown Field Municipal ](https://www.expedia.co.uk/Brown-Field-Municipal-Airport-Hotels.0-aSDM-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Chula Vista ](https://www.expedia.co.uk/Chula-Vista-Hotels-Boutique-Hotel.0-0-d7442-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Chula Vista ](https://www.expedia.co.uk/Chula-Vista-Hotels-Gay-Friendly-Hotel.0-0-d7442-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Chula Vista Hotels ](https://www.expedia.co.uk/Chula-Vista-Hotels.d7442.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Imperial Beach ](https://www.expedia.co.uk/Imperial-Beach-Hotels-Gay-Friendly-Hotel.0-0-d177683-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Imperial Beach ](https://www.expedia.co.uk/Imperial-Beach-Hotels-Pet-Friendly-Hotel.0-0-d177683-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Imperial Beach Hotels ](https://www.expedia.co.uk/Imperial-Beach-Hotels.d177683.Travel-Guide-Hotels) - [Hotels near Len Moore Skate Park ](https://www.expedia.co.uk/Len-Moore-Skate-Park-Hotels.0-l6266345-0.Travel-Guide-Filter-Hotels) - [Nestor Hotels ](https://www.expedia.co.uk/Nestor-San-Diego-Hotels.0-n553248635976476281-0.Travel-Guide-Filter-Hotels) - [Hotels near North Island Credit Union Amphitheatre ](https://www.expedia.co.uk/North-Island-Credit-Union-Amphitheatre-Hotels.0-l6128061-0.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Otay Mesa West ](https://www.expedia.co.uk/Otay-Mesa-West-San-Diego-Hotels-Gay-Friendly-Hotel.0-n553248625809641010-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Otay Mesa West Hotels ](https://www.expedia.co.uk/Otay-Mesa-West-San-Diego-Hotels.0-n553248625809641010-0.Travel-Guide-Filter-Hotels) - [Palm City Hotels ](https://www.expedia.co.uk/Palm-City-San-Diego-Hotels.0-n553248635976470391-0.Travel-Guide-Filter-Hotels) - [Rancho del Rey Hotels ](https://www.expedia.co.uk/Rancho-Del-Rey-Chula-Vista-Hotels.0-n553248635976480627-0.Travel-Guide-Filter-Hotels) - [Rancho - Del Rey II Hotels ](https://www.expedia.co.uk/Rancho-Del-Rey-II-Chula-Vista-Hotels.0-n553248635976470133-0.Travel-Guide-Filter-Hotels) - [Hotels near San Ysidro Border Crossing ](https://www.expedia.co.uk/San-Ysidro-Border-Crossing-Hotels.0-l553248621551385128-0.Travel-Guide-Filter-Hotels) - [Extended Stay America Hotels in San Ysidro ](https://www.expedia.co.uk/San-Ysidro-Hotels-Extended-Stay-America.0-0-d8380--bExtendedStayAmerica.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in San Ysidro ](https://www.expedia.co.uk/San-Ysidro-Hotels-Pet-Friendly-Hotel.0-0-d8380-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [San Ysidro Hotels ](https://www.expedia.co.uk/San-Ysidro-Hotels.d8380.Travel-Guide-Hotels) - [Flights to Chula Vista ](https://www.expedia.co.uk/Cheap-Flights-To-Chula-Vista.d7442.Travel-Guide-Flights) - [Flights to San Ysidro ](https://www.expedia.co.uk/Cheap-Flights-To-San-Ysidro.d8380.Travel-Guide-Flights) - [Flights from Brown Field Municipal ](https://www.expedia.co.uk/lp/airports/sdm/flights-from-brown-field-municipal-airport) - [Flights from Imperial Beach ](https://www.expedia.co.uk/lp/flights/177683/flights-from-imperial-beach) - [Flights from Bonita ](https://www.expedia.co.uk/lp/flights/177687/flights-from-bonita) - [Flights from San Ysidro ](https://www.expedia.co.uk/lp/flights/8380/flights-from-san-ysidro) - [Flights from Hartford (BDL) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/bdl/sdm/hartford-to-san-diego) - [Flights from Beaumont (BMT) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/bmt/sdm/beaumont-to-san-diego) - [Flights from Burbank (BUR) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/bur/sdm/burbank-to-san-diego) - [Flights from Guangzhou (CAN) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/can/sdm/guangzhou-to-san-diego) - [Flights from Paris (CDG) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/cdg/sdm/paris-to-san-diego) - [Flights from Calipatria (CLR) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/clr/sdm/calipatria-to-san-diego) - [Flights from Charlotte (CLT) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/clt/sdm/charlotte-to-san-diego) - [Flights from Compton (CPM) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/cpm/sdm/compton-to-san-diego) - [Flights from Washington (DCA) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/dca/sdm/washington-to-san-diego) - [Flights from Denver (DEN) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/den/sdm/denver-to-san-diego) - [Flights from Dallas (DFW) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/dfw/sdm/dallas-to-san-diego) - [Flights from Edinburgh (EDI) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/edi/sdm/edinburgh-to-san-diego) - [Flights from Ensenada (ESE) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/ese/sdm/ensenada-to-san-diego) - 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[Flights from Omaha (OMA) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/oma/sdm/omaha-to-san-diego) - [Flights from Pittsburgh (PIT) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/pit/sdm/pittsburgh-to-san-diego) - [Flights from Raleigh (RDU) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/rdu/sdm/raleigh-to-san-diego) - [Flights from San Francisco (SFO) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/sfo/sdm/san-francisco-to-san-diego) - [Flights from Salt Lake City (SLC) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/slc/sdm/salt-lake-city-to-san-diego) - [Flights from Syracuse (SYR) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/syr/sdm/syracuse-to-san-diego) - [Flights from Tijuana (TIJ) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/tij/sdm/tijuana-to-san-diego) - [Flights from Halifax (YHZ) to San Diego (SDM) ](https://www.expedia.co.uk/lp/flights/yhz/sdm/halifax-to-san-diego) - [Bonita Holidays ](https://www.expedia.co.uk/Bonita.d177687.Holidays-City-Breaks) - [Visit Bonita ](https://www.expedia.co.uk/Bonita.dx177687) - [Visit Otay Ranch Village 1 ](https://www.expedia.co.uk/Chula-Vista-Otay-Ranch-Village-1.dx553248635976473906) - [Visit Otay ](https://www.expedia.co.uk/Chula-Vista-Otay.dx177685) - [Chula Vista Holidays ](https://www.expedia.co.uk/Chula-Vista.d7442.Holidays-City-Breaks) - [Visit Chula Vista ](https://www.expedia.co.uk/Chula-Vista.dx7442) - [Visit Imperial Beach ](https://www.expedia.co.uk/Imperial-Beach.dx177683) - [Visit Ocean View Hills ](https://www.expedia.co.uk/San-Diego-Ocean-View-Hills.dx553248635976008220) - [Visit Otay Mesa West ](https://www.expedia.co.uk/San-Diego-Otay-Mesa-West.dx553248625809641010) - [Visit San Ysidro ](https://www.expedia.co.uk/San-Ysidro.dx8380) - [Car hire near Balboa Park ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Balboa-Park.d507458.Car-Hire-Guide) - [Car hire Chula Vista ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Chula-Vista.d7442.Car-Hire-Guide) - [Car hire near Coronado Island ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Coronado-Island.d553248621532638598.Car-Hire-Guide) - [Car hire Coronado ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Coronado.d5917.Car-Hire-Guide) - [Car hire near Downtown San Diego ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Downtown-San-Diego.d800123.Car-Hire-Guide) - [Car hire El Cajon ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-El-Cajon.d6632.Car-Hire-Guide) - [Car hire near Gaslamp Quarter ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Gaslamp-Quarter.d6130021.Car-Hire-Guide) - [Car hire Imperial Beach ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Imperial-Beach.d177683.Car-Hire-Guide) - [Car hire near Kearny Mesa ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Kearny-Mesa.d3000663380.Car-Hire-Guide) - [Car hire near La Jolla Village ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Jolla-Village.d6347758.Car-Hire-Guide) - [Car hire La Jolla ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Jolla.d6126584.Car-Hire-Guide) - [Car hire Lemon Grove ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Lemon-Grove.d177690.Car-Hire-Guide) - [Car hire near Mission Bay ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Mission-Bay.d6185904.Car-Hire-Guide) - [Car hire near Mission Beach Boardwalk ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Mission-Beach-Boardwalk.d553248621555611892.Car-Hire-Guide) - [Car hire near Mission Beach ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Mission-Beach.d506109.Car-Hire-Guide) - [Car hire near Old Town San Diego ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Old-Town-San-Diego.d6347116.Car-Hire-Guide) - [Car hire near Pacific Beach ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Pacific-Beach.d6185751.Car-Hire-Guide) - [Car hire near Port of San Diego ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Port-Of-San-Diego.d6131855.Car-Hire-Guide) - [Car hire Poway ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Poway.d7566.Car-Hire-Guide) - [Car hire near San Diego Automotive Museum ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Diego-Automotive-Museum.d6128052.Car-Hire-Guide) - [Car hire near San Diego Convention Center ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Diego-Convention-Center.d6125294.Car-Hire-Guide) - [Car hire near San Diego-Coronado Bridge ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Diego-Coronado-Bridge.d6069077.Car-Hire-Guide) - [Car hire near San Diego County Regional Airport Authority ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Diego-County-Regional-Airport-Authority.d553248635837549720.Car-Hire-Guide) - [Rental cars San Diego Intl. airport ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Diego-Intl.d5128531.Car-Hire-Guide) - [Car hire San Diego ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Diego.d3073.Car-Hire-Guide) - [Car hire San Ysidro ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Ysidro.d8380.Car-Hire-Guide) - [Car hire Santee ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Santee.d6678.Car-Hire-Guide) - [Car hire near Torrey Pines Golf Course ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Torrey-Pines-Golf-Course.d6128012.Car-Hire-Guide) - [Car hire near USS Midway Museum ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-USS-Midway-Museum.d6065467.Car-Hire-Guide) - [Car hire near San Diego County ](https://www.expedia.co.uk/Destinations-In-San-Diego-County.d178304.Car-Hire-Destinations) - [Chula Vista Holiday Rentals ](https://www.expedia.co.uk/Chula-Vista-Holiday-Rentals.d7442.Travel-Guide-HolidayRentals) - [Imperial Beach Holiday Rentals ](https://www.expedia.co.uk/Imperial-Beach-Holiday-Rentals.d177683.Travel-Guide-HolidayRentals) - [Things to do in Chula Vista ](https://www.expedia.co.uk/Things-To-Do-In-Chula-Vista.d7442.Travel-Guide-Activities) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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