Title: TOP Hotels Suites in South San Diego, CA for 2026 | Expedia.co.uk [South San Diego Travel Guide](https://expedia.co.uk/South-San-Diego.dx553248632063518562)[Hotels in South San Diego](https://expedia.co.uk/South-San-Diego-Hotels.d553248632063518562.Travel-Guide-Hotels)[Holiday Rentals in South San Diego](https://expedia.co.uk/South-San-Diego-Holiday-Rentals.d553248632063518562.Travel-Guide-HolidayRentals)[Flights to South San Diego](https://expedia.co.uk/Cheap-Flights-To-South-San-Diego.d553248632063518562.Travel-Guide-Flights)[Things to do in South San Diego](https://expedia.co.uk/Things-To-Do-In-South-San-Diego.d553248632063518562.Travel-Guide-Activities)[South San Diego Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-South-San-Diego.d553248632063518562.Car-Hire-Guide)[South San Diego Holidays](https://expedia.co.uk/South-San-Diego.d553248632063518562.Holidays-City-Breaks) ![Captured this guy doing a wheelie during a beautiful sunset! #imperialbeach #EndlessSummer #autographhotels #Marriott #piersouthresort](https://images.trvl-media.com/place/177683/d4a8a1a3-bd23-4c6a-826e-e0c1c12dddaa.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Karen Leone # Search Hotels Suites in South San Diego - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on South San Diego Hotels Suites Tonight [17 Dec - 18 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-12-17&endDate=2025-12-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [18 Dec - 19 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248632063518562&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for South San Diego hotels with suites ![Reception](https://images.trvl-media.com/lodging/121000000/120560000/120554700/120554667/047b43f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Quadruple Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120560000/120554700/120554667/c6033e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120560000/120554700/120554667/e1c90551.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/121000000/120560000/120554700/120554667/179e83f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### BORDER PLAZA HOTEL [](https://www.expedia.co.uk/San-Ysidro-Hotels-BORDER-PLAZA-HOTEL.h120554667.Hotel-Information) San Ysidro 7.4/10 Good (50) "Clean and friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Myndee £68 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/San-Ysidro-Hotels-BORDER-PLAZA-HOTEL.h120554667.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/4cbc3cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/e7aa7734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/743ac288.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/580000/570900/570818/5f160fe6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pier South Resort, Autograph Collection by Marriott [](https://www.expedia.co.uk/Imperial-Beach-Hotels-Pier-South-Resort.h570818.Hotel-Information) Imperial Beach 8.4/10 Very good (1001) "Staff was amazing room with the view was just stunning " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alisa £143 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Imperial-Beach-Hotels-Pier-South-Resort.h570818.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/w3836h2556x3y3-467b2b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/720d452f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/w3839h2555x0y3-5f9fe6e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/50000000/49290000/49284700/49284697/e9cd53ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Imperial Beach San Diego [](https://www.expedia.co.uk/Imperial-Beach-Hotels-Hampton-Inn-Suites-Imperial-Beach-San-Diego.h49284697.Hotel-Information) Imperial Beach 9.4/10 Exceptional (951) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal £105 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Imperial-Beach-Hotels-Hampton-Inn-Suites-Imperial-Beach-San-Diego.h49284697.Hotel-Information) ![Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/9aa59122.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/18c3e6b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 10:00 AM to 9:30 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/4b05f608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/810000/806400/806327/025fd645.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Americana Inn [](https://www.expedia.co.uk/San-Ysidro-Hotels-Best-Western-Americana-Inn.h806327.Hotel-Information) San Ysidro 9.0/10 Wonderful (1193) "Amazing time at this place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria de Los Angeles £93 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/San-Ysidro-Hotels-Best-Western-Americana-Inn.h806327.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/eda7e8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/3f975189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/c607b0c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1640000/1632400/1632358/1779e3cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG [](https://www.expedia.co.uk/San-Diego-Hotels-Holiday-Inn-Express-Hotel-Suites-San-Diego-Otay-Mesa.h1632358.Hotel-Information) Otay Mesa 8.0/10 Very good (1559) "Great place to stay. Really clean and helpful staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zulma £101 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/San-Diego-Hotels-Holiday-Inn-Express-Hotel-Suites-San-Diego-Otay-Mesa.h1632358.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/57300/57235/79d129c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57300/57235/59ede676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/60000/57300/57235/19df6caa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laundry room](https://images.trvl-media.com/lodging/1000000/60000/57300/57235/23a11085.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Ysidro, CA - San Diego - Border [](https://www.expedia.co.uk/San-Ysidro-Hotels-Motel-6-San-Ysidro.h57235.Hotel-Information) San Ysidro 7.0/10 Good (1471) "exceptional " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clarissa £56 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/San-Ysidro-Hotels-Motel-6-San-Ysidro.h57235.Hotel-Information) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/673df2c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/c6a042c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/16237f85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/470000/461900/461837/55248c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Suites San Diego Otay Mesa [](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information) Otay Mesa 7.2/10 Good (1008) "Beautiful place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joe £92 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/San-Diego-Hotels-Quality-Suites-San-Diego-Otay-Mesa.h461837.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109310000/109303200/109303139/47ca5782.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109310000/109303200/109303139/e3b4ebcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/110000000/109310000/109303200/109303139/fc6b065d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/110000000/109310000/109303200/109303139/435ce843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ERTH INN by AGA- San Ysidro [](https://www.expedia.co.uk/San-Ysidro-Hotels-Flamingo-Motel.h109303139.Hotel-Information) San Ysidro 7.6/10 Good (41) "Clean rooms very budget friendly great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tracy £53 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/San-Ysidro-Hotels-Flamingo-Motel.h109303139.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/57e60275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/c9d13d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/2602a017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1480000/1475800/1475800/fb95526d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hercor Hotel - Urban Boutique [](https://www.expedia.co.uk/Chula-Vista-Hotels-Hercor-Hotel-Urban-Boutique.h1475800.Hotel-Information) Chula Vista 8.6/10 Excellent (1320) "Great value and location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £69 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Chula-Vista-Hotels-Hercor-Hotel-Urban-Boutique.h1475800.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/bfd1ccfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/84883664.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/2194e09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/22900/22810/83180011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham San Diego Chula Vista [](https://www.expedia.co.uk/Chula-Vista-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Chula-Vista.h22810.Hotel-Information) Chula Vista 8.6/10 Excellent (1498) "Everything was great, staff , Room , clean , great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis £82 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Chula-Vista-Hotels-La-Quinta-Inn-By-Wyndham-San-Diego-Chula-Vista.h22810.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=553248632063518562&adults=2&nearby_group=suites&sort=RECOMMENDED&openPlayBack=true) ## Top South San Diego Hotel Reviews ![Sheraton San Diego Resort](https://images.trvl-media.com/lodging/1000000/20000/11200/11109/w4000h2662x0y0-91d299a1_y.jpg) ### Sheraton San Diego Resort 10/10 Excellent "Great hotel! Enjoyed our rooms and the staff was very accommodating to our party with two small children." [](https://expedia.co.uk/San-Diego-Hotels-Sheraton-San-Diego-Hotel-And-Marina.h11109.Hotel-Information) ![Hard Rock Hotel San Diego](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Clean. Great room " [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![The Sofia Hotel](https://images.trvl-media.com/lodging/2000000/1580000/1573900/1573807/ba6cea84_y.jpg) ### The Sofia Hotel 10/10 Excellent "Downtown any city is not my favorite. I’m happy I did not let this deter me from booking this hotel. We loved the room! We were all very comfortable (2 adults, 3 teens, and large dog). The shower did not get hot and the water would be all over the bathroom floor no matter what we did. We were put in an accessible room. Though not needed, it was a very nice room and the shower could easily accommodate a wheelchair without additional assistance. There also was not any vegan creamer for the Nespresso (but this is something I'm used to). The gym was very nice. They also have a nice yoga studio. I love how dog friendly they were. And there is a grassy area not too far. There’s great food options close by, but if you want quick, there’s a corner bakery and chipotle across the street. And a panera not too far. Parking was easy. We did the LAZ self parking at a discount. Valet was also offered for a little more. There wasnt any EV charging at the LAZ and I’m unsure about valet. Overall, I really like this hotel and would stay again. " [](https://expedia.co.uk/San-Diego-Hotels-The-Sofia-Hotel.h1573807.Hotel-Information) ![The Dana on Mission Bay](https://images.trvl-media.com/lodging/1000000/50000/41000/40953/08585098_y.jpg) ### The Dana on Mission Bay 10/10 Excellent "Exceptional service! Amazingly helpful and kind staff. Practical guest laundry self-service - vey necessary on a long trip. Highly recommend Dana Hotel. " [](https://expedia.co.uk/San-Diego-Hotels-The-Dana-On-Mission-Bay.h40953.Hotel-Information) ![Embassy Suites by Hilton San Diego La Jolla](https://images.trvl-media.com/lodging/1000000/10000/8500/8434/49079311_y.jpg) ### Embassy Suites by Hilton San Diego La Jolla 10/10 Excellent "I stayed here every time we would come down here when I was younger on family trips. Now I’m back years later with my boyfriend everything was Perfect and great service all around " [](https://expedia.co.uk/San-Diego-Hotels-Embassy-Suites-By-Hilton-San-Diego-La-Jolla.h8434.Hotel-Information) ## Frequently asked questions ### What are the best cheap hotels with suites in South San Diego? ### Are there any family-friendly hotels with suites in South San Diego? ### Are there any 5-star hotels with suites in South San Diego? ### Why book your hotel with suites in South San Diego with Expedia? ### How can I find cheap hotels with suites in South San Diego? ### What is there to do in South San Diego near my hotel with suites? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Sports Hotels in Anaheim ](https://www.expedia.co.uk/Anaheim-Hotels-Adventure-Sport-Hotel.0-0-d5921-tAdventureSportHotel.Travel-Guide-Filter-Hotels) - [Business Hotels in Anaheim ](https://www.expedia.co.uk/Anaheim-Hotels-Business-Hotel.0-0-d5921-tBusinessHotel.Travel-Guide-Filter-Hotels) - 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