A monument with a statue on top, in front of a large building with columns.

Find luxury hotels in South Carolina Midlands, SC

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on South Carolina Midlands Luxury Hotels

Our top choices for South Carolina Midlands luxury hotels

1. Holiday Inn Express & Suites Columbia-I-20 @ Clemson Rd by IHG

Holiday Inn Express & Suites Columbia-I-20 @ Clemson Rd by IHG
2.5 star property
Columbia
8.8 out of 10, Excellent, (965 reviews)
"Convenient location. Clean rooms and amenities"
United States
Joseph
The price is £93
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Columbia-I-20 @ Clemson Rd by IHG

2. Hampton Inn Columbia I-20-Clemson Road

Hampton Inn Columbia I-20-Clemson Road
2.5 star property
Columbia
8.8 out of 10, Excellent, (883 reviews)
"I loved the updates. It was clean and relaxing. The breakfast was very good. Front desk was efficient. Pleasant stay."
United States
Cindy
The price is £116
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Columbia I-20-Clemson Road

3. La Quinta Inn by Wyndham Columbia SE / Fort Jackson

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
3.0 star property
Columbia
8.4 out of 10, Very good, (1,043 reviews)
"Great stay."
United States
Sunta
The price is £68
includes taxes & fees
6 Dec - 7 Dec
La Quinta Inn by Wyndham Columbia SE / Fort Jackson

4. Springhill Suites by Marriott Columbia near Fort Jackson

Springhill Suites by Marriott Columbia near Fort Jackson
2.0 star property
Columbia
9.4 out of 10, Exceptional, (874 reviews)
"Very friendly staff very nice and clean rooms would definitely recommend"
United States
Donald
The price is £81
includes taxes & fees
22 Nov - 23 Nov
Springhill Suites by Marriott Columbia near Fort Jackson

5. Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone
2.5 star property
Columbia
9.2 out of 10, Wonderful, (1,164 reviews)
"Very clean and friendly staff"
United States
Ken
The price is £84
includes taxes & fees
6 Dec - 7 Dec
Tru By Hilton Columbia Greystone

6. La Quinta Inn by Wyndham Columbia NE/Fort Jackson

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
3.0 star property
Columbia
8.8 out of 10, Excellent, (2,173 reviews)
"Was a great stay!"
United States
maria
The price is £73
includes taxes & fees
22 Nov - 23 Nov
La Quinta Inn by Wyndham Columbia NE/Fort Jackson

7. Courtyard by Marriott Columbia Northeast/Fort Jackson Area

Courtyard by Marriott Columbia Northeast/Fort Jackson Area
3.0 star property
Columbia
8.8 out of 10, Excellent, (1,003 reviews)
"The stay here was a great experience. Facility was clean and modern. Staff were friendly and helpful. Hotel was easy to find."
United States
Brenda
The price is £94
includes taxes & fees
6 Dec - 7 Dec
Courtyard by Marriott Columbia Northeast/Fort Jackson Area

8. Hilton Garden Inn Columbia Northeast

Hilton Garden Inn Columbia Northeast
3.0 star property
Columbia
9.0 out of 10, Wonderful, (1,001 reviews)
"Staff was helpful in the rooms were very clean"
United States
LaNor
The price is £107
includes taxes & fees
23 Nov - 24 Nov
Hilton Garden Inn Columbia Northeast

9. The Lantern Hotel Columbia

The Lantern Hotel Columbia
4.0 star property
Downtown Columbia
9.8 out of 10, Exceptional, (234 reviews)
"Location for us was perfect. The staff were friendly and very helpful. The hotel was very nice."
United States
Nichole
The price is £119
includes taxes & fees
16 Nov - 17 Nov
The Lantern Hotel Columbia

10. Tru By Hilton Columbia Downtown

Tru By Hilton Columbia Downtown
2.5 star property
Downtown Columbia
9.4 out of 10, Exceptional, (985 reviews)
"Great stay"
United States
Jennifer
The price is £82
includes taxes & fees
25 Nov - 26 Nov
Tru By Hilton Columbia Downtown

11. Holiday Inn Express Hotel & Suites Blythewood by IHG

Holiday Inn Express Hotel & Suites Blythewood by IHG
3.0 star property
Blythewood
8.6 out of 10, Excellent, (1,001 reviews)
"The stay was satisfactory."
United States
Ronnie
The price is £100
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express Hotel & Suites Blythewood by IHG

12. Homewood Suites By Hilton Columbia Downtown

Homewood Suites By Hilton Columbia Downtown
3.0 star property
Downtown Columbia
9.6 out of 10, Exceptional, (168 reviews)
"Great Place to stay"
United States
Brian
The price is £96
includes taxes & fees
23 Nov - 24 Nov
Homewood Suites By Hilton Columbia Downtown

13. Residence Inn by Marriott Columbia Northeast/Fort Jackson Area

Residence Inn by Marriott Columbia Northeast/Fort Jackson Area
3.0 star property
Columbia
9.0 out of 10, Wonderful, (831 reviews)
"Excellent place to stay would recommend to anybody"
United States
Lauren
The price is £121
includes taxes & fees
23 Nov - 24 Nov
Residence Inn by Marriott Columbia Northeast/Fort Jackson Area

14. Springhill Suites By Marriott Columbia North

Springhill Suites By Marriott Columbia North
2.0 star property
Columbia
10.0 out of 10, Exceptional, (8 reviews)
"The included breakfast was very good. The outdoor patio with grill, fire pit and TV was very nice. The room was perfect."
United States
Timothy
The price is £117
includes taxes & fees
23 Nov - 24 Nov
Springhill Suites By Marriott Columbia North

15. Country Inn & Suites by Radisson, Columbia, SC

Country Inn & Suites by Radisson, Columbia, SC
2.5 star property
Columbia
7.8 out of 10, Good, (1,181 reviews)
"beautiful hotel"
United States
Natalia
The price is £60
includes taxes & fees
6 Dec - 7 Dec
Country Inn & Suites by Radisson, Columbia, SC

16. Cambria Hotel Columbia Downtown The Vista

Cambria Hotel Columbia Downtown The Vista
3.5 star property
Downtown Columbia
9.4 out of 10, Exceptional, (1,248 reviews)
"Friendly staff and rooms are extremely clean."
United States
Thomas
The price is £93
includes taxes & fees
29 Nov - 30 Nov
Cambria Hotel Columbia Downtown The Vista

17. Courtyard by Marriott Columbia Cayce

Courtyard by Marriott Columbia Cayce
3.0 star property
Cayce
9.0 out of 10, Wonderful, (772 reviews)
"Nice hotel. Bar and restaurant in lobby was nice."
United States
Brett
The price is £85
includes taxes & fees
23 Nov - 24 Nov
Courtyard by Marriott Columbia Cayce

18. Home2 Suites by Hilton Columbia Southeast Fort Jackson

Home2 Suites by Hilton Columbia Southeast Fort Jackson
3.0 star property
Columbia
9.4 out of 10, Exceptional, (734 reviews)
"Excellent customer service and very accommodating staff. Highly recommend!"
United States
Karen Kay
The price is £118
includes taxes & fees
16 Nov - 17 Nov
Home2 Suites by Hilton Columbia Southeast Fort Jackson

19. Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport
3.0 star property
West Columbia
9.0 out of 10, Wonderful, (1,000 reviews)
"The staff was so friendly and helpful. The food at the restaurant on site was delicious!! The room was clean and bed was comfortable."
United States
SHERI
The price is £83
includes taxes & fees
26 Nov - 27 Nov
Hilton Garden Inn Columbia Airport

20. Sleep Inn Columbia

Sleep Inn Columbia
2.5 star property
Seven Oaks
8.2 out of 10, Very good, (1,224 reviews)
"It was a great stay for me and the family would stay again!"
United States
Emily
The price is £65
includes taxes & fees
26 Nov - 27 Nov
Sleep Inn Columbia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about South Carolina Midlands

South Carolina Midlandsand its attractions for luxury travelers

In the heart of South Carolina Midlands, luxury travellers can immerse themselves in a blend of history, culture, and natural beauty. Start your journey at the stunning Riverbanks Zoo & Garden, where you can stroll through beautifully landscaped gardens and encounter exotic animals in a serene environment – a perfect spot for families to enjoy an engaging day out. Next, explore the historic district of Columbia, with its charming architecture and vibrant arts scene, where upscale boutiques and art galleries await discovery. For a taste of Southern hospitality, indulge in a fine dining experience at The Capital Grille, renowned for its exceptional steaks and extensive wine list. Nature enthusiasts will appreciate a visit to Congaree National Park, where luxury hotels like The Inn at USC provide easy access to hiking trails and breathtaking views of ancient trees. Finally, don’t miss the South Carolina State Museum, which offers a wealth of exhibits ranging from art to science, all housed in a beautifully restored facility. Staying in the Midlands allows for a relaxing exploration of these attractions, with luxury hotels offering impeccable service and amenities, ensuring that your every need is catered to – from spa treatments to gourmet dining experiences.

Top South Carolina Midlands Hotel Reviews

Explore a world of travel with Expedia