Title: Hotels in Santa Pera - Best Santa Pera Hotels from £22 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Pera](https://expedia.co.uk/Santa-Pera-Holiday-Rentals.d553248635975875222.Travel-Guide-HolidayRentals)[Santa Pera Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Pera.d553248635975875222.Car-Hire-Guide)[Santa Pera Holidays](https://expedia.co.uk/Santa-Pera.d553248635975875222.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Pera Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-02-15&d1=2026-02-15&endDate=2026-02-17&d2=2026-02-17&amenities=SPA_ON_SITE) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-02-15&d1=2026-02-15&endDate=2026-02-17&d2=2026-02-17&amenities=POOL) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-02-15&d1=2026-02-15&endDate=2026-02-17&d2=2026-02-17&amenities=OCEAN_VIEW) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-02-15&d1=2026-02-15&endDate=2026-02-17&d2=2026-02-17&lodging=APARTMENT) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-02-15&d1=2026-02-15&endDate=2026-02-17&d2=2026-02-17&amenities=PETS) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-02-15&d1=2026-02-15&endDate=2026-02-17&d2=2026-02-17&amenities=HOT_TUB) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-02-15&d1=2026-02-15&endDate=2026-02-17&d2=2026-02-17&travelerType=family_friendly) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Pera%2C+San+Miguelito%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975875222&latLong=9.05%2C-79.466698&adults=2&startDate=2026-02-15&d1=2026-02-15&endDate=2026-02-17&d2=2026-02-17&lodging=CONDO) ## Check prices for these dates Tonight [1 Feb - 2 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975875222&startDate=2026-02-01&endDate=2026-02-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [2 Feb - 3 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975875222&startDate=2026-02-02&endDate=2026-02-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [6 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975875222&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975875222&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Pera hotels ![Apartment, 3 Bedrooms, Accessible, Pool View | Pool | Outdoor pool](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/76eefaf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Accessible, Pool View | Children’s area](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/w2048h1520x0y0-47515268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Accessible, Pool View | Interior](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/5864a396.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Accessible, Pool View | 3 bedrooms](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/094709c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3 Bedroom Apartment in San Miguelito, Panama City [](https://www.expedia.co.uk/San-Miguelito-Hotels-Apto-3-Hab-Piscina-15-Tocumen-Min-Airport.h119462129.Hotel-Information) José Domingo Espinar - Stylish Panama apartment with outdoor pool near shopping centres and coastal views. £80 includes taxes & fees 4 Feb - 5 Feb [](https://www.expedia.co.uk/San-Miguelito-Hotels-Apto-3-Hab-Piscina-15-Tocumen-Min-Airport.h119462129.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/10000000/9020000/9013300/9013235/743c7e0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/10000000/9020000/9013300/9013235/ff8349df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/10000000/9020000/9013300/9013235/509d2d80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/10000000/9020000/9013300/9013235/0e811be9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Latino [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Latino.h9013235.Hotel-Information) Calidonia 6.6/10 (226 reviews) - Enjoy city living in Panama's vibrant heart, with a refreshing rooftop terrace and pool. "Staff at front desk was very unprofessional and disrespectful. For some reason they had trouble finding my reservation after repeatedly telling them all the information. Three different people at the desk looked through their system and couldn’t find it while I spent over 30 minutes standing there. They kept sending me away telling me I was at the wrong place. While showing them even the hotel’s picture and address. Another reason why I wouldn’t really recommend the place for people touring as... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Evelyn Vanessa [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Latino.h9013235.Hotel-Information) ![Ecotours](https://images.trvl-media.com/lodging/10000000/9560000/9560000/9559935/e3c29c9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ecotours](https://images.trvl-media.com/lodging/10000000/9560000/9560000/9559935/23e2a20b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9560000/9560000/9559935/d83eff34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/10000000/9560000/9560000/9559935/5fd1457c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Pension Corona [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Pension-Corona.h9559935.Hotel-Information) Calidonia 7.8/10 Good (114 reviews) - Stay near Cinta Costera with free parking and 24-hour room service. "Great spot for the price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) frank [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Pension-Corona.h9559935.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/c1c9d6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Fusion cuisine ](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/255ee499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Geo Orga by Mariery Young | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/4fafb76c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/5000000/4890000/4880500/4880470/fab1c02b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tantalo Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) Casco Viejo 8.8/10 Excellent (280 reviews) - Artistic boutique hotel with rooftop terrace moments from Panama City's heart. "Staff was amazing!! Room was great as well!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John [](https://www.expedia.co.uk/Panama-City-Hotels-Tantalo-Hotel-Kitchen-Roofbar.h4880470.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/61000000/60170000/60167400/60167389/eaad68b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/61000000/60170000/60167400/60167389/db492c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, City View | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/61000000/60170000/60167400/60167389/29529d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/61000000/60170000/60167400/60167389/c27e1795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Canova [](https://www.expedia.co.uk/Panama-City-Hotels-Canova.h60167389.Hotel-Information) Calidonia 8.2/10 Very good (142 reviews) - Centrally located Panama City hotel offers easy access to top attractions and sights. "Very close place to everything. Very affordable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alex £23 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Canova.h60167389.Hotel-Information) ![Double Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2500000/2495000/2494953/5d5b688d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/3000000/2500000/2495000/2494953/f55bb4f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2500000/2495000/2494953/6ba7cf2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2500000/2495000/2494953/0448ebed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Discovery [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Discovery.h2494953.Hotel-Information) Calidonia 7.4/10 Good (173 reviews) - Explore Panama City with easy access to Cinta Costera and Avenida Balboa. "Rooms was nice and clean. Transportation was easy area was peaceful. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roniald £22 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Discovery.h2494953.Hotel-Information) ![Classic Double Room, 1 Double Bed, Non Smoking | In-room safe, desk, soundproofing, free WiFi](https://images.trvl-media.com/lodging/30000000/29420000/29417900/29417859/f2c20ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/30000000/29420000/29417900/29417859/86a0b4e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/30000000/29420000/29417900/29417859/3012da90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/30000000/29420000/29417900/29417859/80e5197c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Acapulco [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Acapulco.h29417859.Hotel-Information) Calidonia 7.8/10 Good (131 reviews) - Explore Panama City with 10-minute walks to Avenida Balboa and Cinta Costera. "Place is convenient for local shopping local restaurants and access to train. The room is basic but not in a bad way it not luxury but it was clean and staff were all friendly I was there for a short stay and had no complaints. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £23 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Acapulco.h29417859.Hotel-Information) ![3 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e50f6f0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/0e5b4d5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/0311490e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/cfdbe00f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Playa Bonita Panama [](https://www.expedia.co.uk/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) Veracruz 8.0/10 Very good (1,005 reviews) "Beautiful property and amazing staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CARMEN £190 includes taxes & fees 28 Feb - 1 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/60cd745e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/3eabd2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/bdcbfd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/92484b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Magnolia Inn [](https://www.expedia.co.uk/Panama-City-Hotels-Magnolia-Inn.h24165406.Hotel-Information) Casco Viejo 8.8/10 Excellent (436 reviews) - A Panama City hotel near Cinta Costera with helpful staff and daily service. "Great customer service, wonderful room and great location. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sharon £78 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Magnolia-Inn.h24165406.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/27000000/26770000/26766400/26766369/eaae42c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/27000000/26770000/26766400/26766369/f2a11d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/27000000/26770000/26766400/26766369/027c7cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/27000000/26770000/26766400/26766369/92eec4ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residencial & Hotel Palazzo [](https://www.expedia.co.uk/Panama-City-Hotels-Residencial-Hotel-Palazzo.h26766369.Hotel-Information) Calidonia 7.4/10 Good (122 reviews) - Centrally located Panama City hotel near Avenida Balboa and transit options. "I recommend this place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Crystal [](https://www.expedia.co.uk/Panama-City-Hotels-Residencial-Hotel-Palazzo.h26766369.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8120000/8115400/8115364/fd309502.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Local cuisine](https://images.trvl-media.com/lodging/9000000/8120000/8115400/8115364/b0782bdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8120000/8115400/8115364/399c27ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/9000000/8120000/8115400/8115364/1b511a49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Vía España [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Via-Espana.h8115364.Hotel-Information) Calidonia 6.2/10 (174 reviews) "Don’t stay there it’s the " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andreas [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Via-Espana.h8115364.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/16b35949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/92c9ca27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/25c339ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Suite, Sea View | Premium bedding, soundproofing, free WiFi](https://images.trvl-media.com/lodging/17000000/16280000/16271000/16270978/d5edf799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Caprichosa [](https://www.expedia.co.uk/Taboga-Hotels-Villa-Caprichosa.h16270978.Hotel-Information) Taboga 9.8/10 Exceptional (45 reviews) - Experience tropical paradise at Taboga's beachside villa with pool and massage services. "Would definitely visit again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £201 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Taboga-Hotels-Villa-Caprichosa.h16270978.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside views, serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/88cca748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/dc6a5657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/d73825f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) Tocumen 8.6/10 Excellent (1,851 reviews) - Tranquil oasis near Panama City Airport with lush gardens and tropical pool. "Clean room and friendly staff. Breakfast was very good also. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ramon £101 includes taxes & fees 5 Feb - 6 Feb [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/bf18b63d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/98e777ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/1c70a5cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/a00712ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Panama House Bed & Breakfast [](https://www.expedia.co.uk/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) Bella Vista 9.0/10 Wonderful (189 reviews) - Panama House close to attractions with ample parking and convenient transit. "It was a great stay in a great neighborhood with many food and beverage options, fantastic hosts and an interesting mix of people " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Brad £33 includes taxes & fees 14 Feb - 15 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/68c712fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/b8687db2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Room | Living area | Books, video library](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/edd11e34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Winery](https://images.trvl-media.com/lodging/114000000/113480000/113477600/113477576/921ce9a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Plaza Herrera [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Herrera.h113477576.Hotel-Information) Casco Viejo 10/10 Exceptional (16 reviews) - Beautiful historic hotel in Panama City's vibrant heart with winery and bars. "Hotel Plaza Herrera is a real gem and the staff is all diamonds! We will be back! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neal £220 includes taxes & fees 21 Feb - 22 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Herrera.h113477576.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c696a538.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c7eb2b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/4b5df5ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/76d19433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gamboa Rainforest Reserve [](https://www.expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) Colon 7.8/10 Good (688 reviews) - Experience spectacular wildlife and panoramic forest views in Panama's rainforest. "Attentive staff and awesome dining facility. Beautiful quiet place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ana £109 includes taxes & fees 4 Feb - 5 Feb [](https://www.expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/6785cd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/532b8393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Double Beds, Pool View | Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/be13d503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/b2fe58e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Panama Canal by IHG [](https://www.expedia.co.uk/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) Panama City 8.6/10 Excellent (450 reviews) - Tropical retreat overlooking the Panama Canal with an outdoor pool and fitness centre. "The staff was so cordial and nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonny £83 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/9000000/8120000/8115300/8115201/447f7358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/9000000/8120000/8115300/8115201/36a02e57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/9000000/8120000/8115300/8115201/92b91839.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8120000/8115300/8115201/2338b3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Costa Inn [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Costa-Inn.h8115201.Hotel-Information) Calidonia 7.0/10 Good (555 reviews) - Walk to Avenida Balboa and explore Panama City from this convenient hotel. "Nice bathroom " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Derrick [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Costa-Inn.h8115201.Hotel-Information) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/02cb9f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/6bacf09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | Living area | 55-inch LED TV with digital channels, TV, books](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/767f29dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Loft (Loft) | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/1fe25d14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Compañía Casco Antiguo [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-La-Compania.h71135966.Hotel-Information) Casco Viejo 9.8/10 Exceptional (265 reviews) - Experience Panama City's colonial charm with 5 restaurants and a full-service spa. "Great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erik £264 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-La-Compania.h71135966.Hotel-Information) ![Interior detail](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/5ba20b7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/83a3d8ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/27481125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/13000000/12100000/12092000/12091977/a3824af3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Casa Panamá [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Casa-Panama.h12091977.Hotel-Information) Casco Viejo 7.4/10 Good (609 reviews) - Experience the vibrant side of Panama City with airport shuttle and nightlife access. "Great location, clean, exactly as advertised!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Natasha £55 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Casa-Panama.h12091977.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-15&endDate=2026-02-16®ionId=553248635975875222&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Pera-Hotels.d553248635975875222.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Pera-Hotels.d553248635975875222.Travel-Guide-Hotels) ## Top Santa Pera Hotel Reviews ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "excellent room and location" [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Courtyard by Marriott Panama Metromall](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/w3989h2656x0y8-13f5112b_y.jpg) ### Courtyard by Marriott Panama Metromall 10/10 Excellent "Excellent" [](https://expedia.co.uk/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Always great value for the price!" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Simple, clean hotel with a good location and great value for a quick stay in Panama City." [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/68ce59ee_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Nice stuff. Very welcoming and cheerful people. Clean. Closhopping centers " [](https://expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The first room was clean but the window has moisture in between the panel so you can’t see outside. The next day I told the front desk and they rectified it by moving us to a different room with no hustle " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "The room was very comfortable, air-condition worked great. " [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "The location was terrific making it easy to catch an Uber to pretty much anywhere you wanted to go. Pool & fitness area were as expected & the room was comfortable. We were here for 4 nights. Loved that it was attached to the mall." [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Room was clean and check in was quick. Literally right next to the airport so it is perfect for a layover " [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ## More cheap stays in Santa Pera ![Panama House Bed & Breakfast](https://images.trvl-media.com/lodging/12000000/11850000/11845100/11845091/0f765b96_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Panama House Bed & Breakfast Calle 1era El Carmen- Casa # 32 Panama City £33 14 Feb - 15 Feb includes taxes & fees 8.8/10 Excellent! (189 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Panama-House-Bed-Breakfast.h11845091.Hotel-Information) ![Viajero Casco Viejo Hostel](https://images.trvl-media.com/lodging/119000000/118800000/118790900/118790803/2c436ca6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Viajero Casco Viejo Hostel Avenida B, Calle 12 Este, Casco Viejo Panama City £36 8 Feb - 9 Feb includes taxes & fees 7.6/10 Good! (15 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Viajero-Casco-Viejo-Hostel.h118790803.Hotel-Information) ![Magnolia Inn](https://images.trvl-media.com/lodging/25000000/24170000/24165500/24165406/60cd745e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Magnolia Inn 8-18 Calle 8 y Calle Boquete Panama City Panama £78 9 Feb - 10 Feb includes taxes & fees 8.8/10 Excellent! (436 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Magnolia-Inn.h24165406.Hotel-Information) ![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arcadia Condo Suites Calle rio mar Panama City Panamá Province £100 2 Mar - 3 Mar includes taxes & fees 9.2/10 Wonderful! (202 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![ORHO HOTEL BOUTIQUE PANAMA Airport](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/febf3b4c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### ORHO HOTEL BOUTIQUE PANAMA Airport Av. Domingo Díaz Tocumen Provincia de Panamá £114 3 Feb - 4 Feb includes taxes & fees 8.8/10 Excellent! (59 reviews) [](https://expedia.co.uk/Tocumen-Hotels-ORHO-HOTEL-BOUTIQUE-PANAMA-Airport.h119860522.Hotel-Information) ![Hotel República](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/9363bddf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel República Plaza 5 De Mayo Final Ave Panama City Panama [Get rates](https://expedia.co.uk/Hotel-Search?startDate=15%2F02%2F2026&endDate=16%2F02%2F2026&selected=3257592&PinnedHotelID=3257592&HadPinnedHotel=true®ionId=553248635975875222) 6.4/10 (181 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Santa Pera? ### What are some of the best holiday rentals that Santa Pera has to offer? ### If I need to cancel my hotel reservation in Santa Pera, will I receive a refund? ### What are some hotels with pools in Santa Pera? ### What's it like to stay in Santa Pera? ### What are the top places to visit in Santa Pera? ### What's the seasonal weather in Santa Pera? ## Explore a world of travel with Expedia - 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