Santa Pera Holidays from £547

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Santa Pera Holiday

Say goodbye to the stress of planning and hello to a Santa Pera holiday package. With your travel details organised before you go, you can focus on discovering the best of this city, starting with El Cangrejo, which is great for distilleries and craft breweries, bars and pubs and cafes. Metromall Panama is among the must-see attractions to check off your to-do list during a trip to Santa Pera. That dream Santa Pera holiday is just a few clicks away. Search accommodation, flights and more on Expedia for a trip that's tailored just for you.

Top Santa Pera Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Tocumen Airport
Price was £952, price is now £547 per person
£547
per person
27 Dec - 2 Jan
found 1 day ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
8.6/10 Excellent! (1,824 reviews)

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was £2,432, price is now £1,017 per person
£1,017
per person
23 Dec - 28 Dec
found 20 hours ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9.2/10 Wonderful! (1,015 reviews)

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was £1,767, price is now £804 per person
£804
per person
27 Dec - 2 Jan
found 1 day ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
8.6/10 Excellent! (1,803 reviews)
Nice atmosphere

Reviewed on 4 Nov 2026

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was £1,099, price is now £687 per person
£687
per person
27 Dec - 2 Jan
found 1 day ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
9/10 Wonderful! (6,099 reviews)
Staff were nice and rooms were okay. Food was very good.

Reviewed on 4 Nov 2026

Decapolis Hotel Panama City

Decapolis Hotel Panama City

4 out of 5
San Francisco
Price was £941, price is now £607 per person
£607
per person
27 Dec - 2 Jan
found 1 day ago
Return direct flight included
Georgetown (GEO) to Panama City (PTY)
8.6/10 Excellent! (1,727 reviews)

Santa Pera Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Max Temp Winter
29ºC
Max Temp Summer
29ºC

Top hotels in Santa Pera

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £108 per night from 1 Dec to 2 Dec
£108
1 Dec - 2 Dec
includes taxes & fees
9/10 Wonderful! (6,178 reviews)
"Staff were nice and rooms were okay. Food was very good."

Reviewed on 4 Nov 2026

Hotel Riu Plaza Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £95 per night from 3 Dec to 4 Dec
£95
3 Dec - 4 Dec
includes taxes & fees
7.8/10 Good! (1,009 reviews)
"No me gustó desayuno todos los días lo mismo y poca cantidad"

Reviewed on 4 Nov 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
The price is £110 per night from 18 Nov to 19 Nov
£110
18 Nov - 19 Nov
includes taxes & fees
8.6/10 Excellent! (1,837 reviews)
"Nice atmosphere"

Reviewed on 4 Nov 2026

Megapolis Hotel Panamá
See all 1,809 properties in Santa Pera
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in Santa Pera

Panama Canal: The Most Complete Monkey Island Experience

Panama Canal: The Most Complete Wildlife Experience

£27
per adult
100% of travellers recommend
Panama Canal: The Most Complete Wildlife Experience
From Panama City: San Blas Islands Tour with Island Hopping

From Panama City: San Blas Islands Tour with Island Hopping

£108
per adult
98% of travellers recommend
From Panama City: San Blas Islands Tour with Island Hopping
Panama Canal Half Transit Experience

Panama Canal Partial Transit

£112
per adult
84% of travellers recommend
Panama Canal Partial Transit
See all activities in Santa Pera

Frequently asked questions

How much does a Santa Pera travel package cost?
Maybe less than you imagined — from just £547, in fact! By bundling hotels, flights and car rentals into a tailor-made package, your getaway to Santa Pera is just clicks away.
If I'm not able to travel, can I cancel my Santa Pera travel package?
Don't stress if you're rethinking your Santa Pera travel package — it's possible to cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We totally understand your circumstances can change suddenly, so look up our Customer Service Portal if that happens. When you're ready to make changes, we'll be here to help.
How do I get a cheap travel package to Santa Pera?
Combining your flight and hotel with Expedia won't just save you time — it'll save you cash too. A Santa Pera travel package makes it simple to organise the ideal trip. With more than 550 airlines all over the world to pick from, finding flights that suit your schedule won't be a hassle. On top of that, we've got over 1,000,000 properties globally to choose from. Now that's what you call choice. No matter who you are, Expedia will help show you the world.
Does Expedia offer Book Now, Pay Later Santa Pera holidays?
Good news! We do. Expedia has partnered with online lender Klarna to help you easily pay for your trip in manageable instalments. Simply pick the payment plan best suited to your needs during the checkout process and take away the stress of budgeting for your next trip. Don't forget to bundle your flights, hotel and car hire with Expedia to get the biggest bang for your holiday buck. Take a look at our flexible payment options below:

  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's monthly instalment plans. If making bite-sized repayments each month works for you, choose this option during the checkout process.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay for your holiday across multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the total upfront) makes it easier to hit that "book now" button, go for a low deposit holiday payment plan with Klarna.

Where should I stay in Santa Pera?
There's lots to explore in Santa Pera, so spend your nights near its best attractions and allow yourself more time sightseeing. Metromall Panama is one place to add to your must-see list.
What are the top hotels in Santa Pera?
If it's your first time in Santa Pera, secure a room at Courtyard by Marriott Panama Metromall or Los Panas Hostel. Both offer friendly service and are popular options with lots of travellers.
How far in advance should I book my Santa Pera holiday?
The earlier, the better. Air carriers typically release flight tickets up to 12 months prior to departure, and this is your chance to score some rock-bottom prices. Just been told you should take some holiday time next week? No problem! Expedia are never short of fantastic bargains to help you have the getaway of your dreams, at an affordable price.
What does an Expedia Santa Pera travel package include?
Packages include rental cars, hotels and flights, but you can combine any of them to create your dream Santa Pera trip. You can also add on fun stuff like activities and tours once you've made your booking. You're in charge! When you combine your bookings with Expedia, you'll get access to discounts you won't find elsewhere.
What should I know before booking a Santa Pera travel package?
When you book your flights, hotels and car rentals together, you'll nab great discounts. Whether you're planning a beach break in a villa or prefer to stay in a luxurious city hotel, Expedia can help make it happen.
Can I choose my airline with a Santa Pera Expedia travel package?
Expedia offers access to more than 550 partner airlines worldwide, so you definitely can. Simply choose the carrier you want and create your ideal Santa Pera escape.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.