Title: £543 Cheap Flights from Istanbul to Panama City (IST to PTY) - Expedia.co.uk ![Panoramic view at the Downtown of Panama City - Panama](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/2897/e48f6143-9130-47fe-8b71-977ffb07b927.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £543 Cheap Flights from Istanbul (IST) to Panama City (PTY) [View £543 flight on Sun, 5 Apr 2026](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:IST,to:PTY,departure:05/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:542.60&airProductToken=AQpnCjIIwYwBEgQxMzkxGMicASDiMCj1vokDMNHAiQM4TEAAWAFqBUxJR0hUcghOR0xGQkJMQQoxCMGMARIDNDc0GOIwIO_EASjrw4kDMPXIiQM4TkABWAFqBUxJR0hUcghOR0xGQkJMQRIKCAEQARgBKgJBRhgBIgQIARABKAIoAygEMAE) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Istanbul Airport (IST) to Tocumen Intl. Airport (PTY) - ![Air Europa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UX.svg) Air Europa [](https://www.expedia.co.uk/Flights-Search?leg1=from:ist,to:pty,departure:12/11/2025TANYT&leg2=from:pty,to:ist,departure:19/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UX"}}]) - ![Turkish Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_TK.svg) Turkish Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:ist,to:pty,departure:12/11/2025TANYT&leg2=from:pty,to:ist,departure:19/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"TK"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:ist,to:pty,departure:12/11/2025TANYT&leg2=from:pty,to:ist,departure:19/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Air France](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AF.svg) Air France [](https://www.expedia.co.uk/Flights-Search?leg1=from:ist,to:pty,departure:12/11/2025TANYT&leg2=from:pty,to:ist,departure:19/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AF"}}]) - ![KLM](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_KL.svg) KLM [](https://www.expedia.co.uk/Flights-Search?leg1=from:ist,to:pty,departure:12/11/2025TANYT&leg2=from:pty,to:ist,departure:19/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"KL"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:ist,to:pty,departure:12/11/2025TANYT&leg2=from:pty,to:ist,departure:19/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![British Airways](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_BA.svg) British Airways [](https://www.expedia.co.uk/Flights-Search?leg1=from:ist,to:pty,departure:12/11/2025TANYT&leg2=from:pty,to:ist,departure:19/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"BA"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Istanbul (IST) to Panama City (PTY) Prices were available within the past 7 days and start at £543 for one-way flights and £695 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Sun, 1 Feb - Wed, 18 Feb IST Istanbul PTY Panama City £695 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:01/02/2026TANYT&leg2=from:PTY,to:IST,departure:18/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:694.20&airProductToken=AQpgCi8I1bABEgQxNjg0GMicASCMGCiXgIQDMJaChAM4WkAAWAFqBExJVEVyBlpMWVI2TAotCNWwARICNTUYjBgg78QBKLKLhAMwrZCEAzhaQAFYAWoETElURXIGWkxZUjZMCmAKLQjVsAESAjU2GO_EASCMGCiWxYUDMNXJhQM4WkAAWAFqBExJVEVyBlpMWVI2TAovCNWwARIEMTY4MxiMGCDInAEoitOFAzDr1IUDOFpAAVgBagRMSVRFcgZaTFlSNkwSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Wed, 4 Mar - Tue, 10 Mar IST Istanbul PTY Panama City £716 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:04/03/2026TANYT&leg2=from:PTY,to:IST,departure:10/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:715.44&airProductToken=AQpgCi8I1bABEgQxNjg0GMicASCMGCj33IYDMPbehgM4WkAAWAFqBExJVEVyBlpMWVI2TAotCNWwARICNTUYjBgg78QBKJLohgMwje2GAzhaQAFYAWoETElURXIGWkxZUjZMCmAKLQjVsAESAjU2GO_EASCMGCiWpocDMNWqhwM4WkAAWAFqBExJVEVyBlpMWVI2TAovCNWwARIEMTY4MxiMGCDInAEoirSHAzDrtYcDOFpAAVgBagRMSVRFcgZaTFlSNkwSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Sat, 24 Jan - Sat, 28 Feb IST Istanbul PTY Panama City £718 Return found 14 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:24/01/2026TANYT&leg2=from:PTY,to:IST,departure:28/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:717.70&airProductToken=AQpgCi8I1bABEgQxNjg0GMicASCMGCiXpoMDMJaogwM4WkAAWAFqBExJVEVyBlpMWVI2TAotCNWwARICNTUYjBgg78QBKLKxgwMwrbaDAzhaQAFYAWoETElURXIGWkxZUjZMCmAKLQjVsAESAjU2GO_EASCMGCjWtYYDMJW6hgM4WkAAWAFqBExJVEVyBlpMWVI2TAovCNWwARIEMTY4MxiMGCDInAEoysOGAzCrxYYDOFpAAVgBagRMSVRFcgZaTFlSNkwSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Fri, 23 Jan - Sun, 8 Feb IST Istanbul PTY Panama City £726 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:23/01/2026TANYT&leg2=from:PTY,to:IST,departure:08/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:725.44&airProductToken=AQpgCi8I1bABEgQxNjg0GMicASCMGCj3moMDMPacgwM4WkAAWAFqBExJVEVyBlpMWVI2TAotCNWwARICNTUYjBgg78QBKJKmgwMwjauDAzhaQAFYAWoETElURXIGWkxZUjZMCmAKLQjVsAESAjU2GO_EASCMGCjW1IQDMJXZhAM4WkAAWAFqBExJVEVyBlpMWVI2TAovCNWwARIEMTY4MxiMGCDInAEoyuKEAzCr5IQDOFpAAVgBagRMSVRFcgZaTFlSNkwSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 5 Feb - Sat, 21 Feb IST Istanbul PTY Panama City £731 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:05/02/2026TANYT&leg2=from:PTY,to:IST,departure:21/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:730.44&airProductToken=AQpgCi8I1bABEgQxNjg0GMicASCMGCiXrYQDMJavhAM4WkAAWAFqBExJVEVyBlpMWVI2TAotCNWwARICNTUYjBgg78QBKLK4hAMwrb2EAzhaQAFYAWoETElURXIGWkxZUjZMCmAKLQjVsAESAjU2GO_EASCMGCj25oUDMLXrhQM4WkAAWAFqBExJVEVyBlpMWVI2TAovCNWwARIEMTY4MxiMGCDInAEo6vSFAzDL9oUDOFpAAVgBagRMSVRFcgZaTFlSNkwSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) ![Air Europa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UX.gif) Thu, 8 Jan - Fri, 23 Jan IST Istanbul PTY Panama City £785 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:08/01/2026TANYT&leg2=from:PTY,to:IST,departure:23/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:784.20&airProductToken=AQpgCi8I1bABEgQxNjg0GMicASCMGCiX8oEDMJb0gQM4UUAAWAFqBExJVEVyBlFMWVI2TAotCNWwARICNTUYjBgg78QBKLL9gQMwrYKCAzhRQAFYAWoETElURXIGUUxZUjZMCmAKLQjVsAESAjU2GO_EASCMGCjWoIMDMJWlgwM4WkAAWAFqBExJVEVyBlpMWVI2TAovCNWwARIEMTY4MxiMGCDInAEoyq6DAzCrsIMDOFpAAVgBagRMSVRFcgZaTFlSNkwSCggBEAEYASoCVVgYASIECAEQASgCKAMoBDAB) ![KLM](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/KL.gif) Fri, 23 Jan - Sun, 8 Feb IST Istanbul PTY Panama City £807 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:23/01/2026TANYT&leg2=from:PTY,to:IST,departure:08/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:806.90&airProductToken=AQppCjMIy5gBEgQxOTYwGMicASCAkwEon5uDAzD7nIMDOExAAFgBagVMSUdIVHIIUkdMMEtCTEEKMgjLmAESAzc2MxiAkwEg78QBKPmlgwMwl6uDAzhSQAFYAWoFTElHSFRyCFJHTDBLQkxBCmcKMQjBjAESAzQ3NRjvxAEg4jAoiNWEAzDb2YQDOFJAAFgBagVMSUdIVHIIUkdMMEtCTEEKMgjBjAESBDEzOTAY4jAgyJwBKMDdhAMwkt-EAzhMQAFYAWoFTElHSFRyCFJHTDBLQkxBEgoIARABGAEqAktMGAEiBAgBEAEoAigDKAQwAQ) ![Air France](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AF.gif) Sun, 1 Feb - Wed, 18 Feb IST Istanbul PTY Panama City £817 Return found 5 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:01/02/2026TANYT&leg2=from:PTY,to:IST,departure:18/02/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:816.10&airProductToken=AQpnCjIIwYwBEgQxMzkxGMicASDiMCiu-oMDMI_8gwM4TEAAWAFqBUxJR0hUcghSR0wwS0JMQQoxCMGMARIDNDc4GOIwIO_EASiSgIQDMKaFhAM4UkABWAFqBUxJR0hUcghSR0wwS0JMQQpnCjEIwYwBEgM0NzUY78QBIOIwKMjFhQMwoMqFAzhSQABYAWoFTElHSFRyCFJHTDBLQkxBCjIIwYwBEgQxMzkwGOIwIMicASiAzoUDMNLPhQM4TEABWAFqBUxJR0hUcghSR0wwS0JMQRIKCAEQARgBKgJBRhgBIgQIARABKAIoAygEMAE) ![British Airways](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/BA.gif) Tue, 3 Mar - Mon, 9 Mar IST Istanbul PTY Panama City £962 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:03/03/2026TANYT&leg2=from:PTY,to:IST,departure:09/03/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:961.74&airProductToken=AQqWAQowCMKCARIDNjc3GMicASDriQEoy9CGAzDU0oYDOFFAAFgBagNCQUdyCFFMTkM0ME02CjAIwoIBEgQ3MDY3GOuJASCMGCic1IYDMK3VhgM4UUABWAFqA0JBR3IIUUxOQzQwTTYKMAjCggESBDQyMjcYjBgg78QBKKDbhgMwueCGAzhRQAFYAWoDQkFHcghRTE5DNDBNNgqWAQowCMKCARIENTUwMxjvxAEgjAIoopiHAzDbmYcDOE5AAFgBagNCQUdyCE5MTkM0ME02CjAIwoIBEgQxNTAwGIwCIOuJASiem4cDMLWfhwM4TkABWAFqA0JBR3IITkxOQzQwTTYKMAjCggESAzY4MBjriQEgyJwBKOahhwMw0aOHAzhOQAFYAWoDQkFHcghOTE5DNDBNNhIKCAEQARgBKgJCQRgBIgQIARABKAIoAygEMAE) ![United](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/UA.gif) Mon, 10 Nov - Mon, 17 Nov IST Istanbul PTY Panama City £976 Return found 2 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:IST,to:PTY,departure:10/11/2025TANYT&leg2=from:PTY,to:IST,departure:17/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:975.80&airProductToken=AQqbAQoyCNWCARIEOTEyNxjInAEgpQQostX8AjDw1vwCOFNAAFgBagdFQ09OT01ZcgZTTkNTMEYKMQjVggESBDg4MjcYpQQgiBgoq9n8AjDC3fwCOFNAAVgBagdFQ09OT01ZcgZTTkNTMEYKMgjVggESBDcwNjUYiBgg78QBKPXh_AIwoeT8AjhTQAFYAWoHRUNPTk9NWXIGU05DUzBGCpoBCjII1YIBEgQ3MTU2GO_EASCIGCiTqf0CMLar_QI4TEAAWAFqB0VDT05PTVlyBkxOQ1MwVgowCNWCARIDOTMyGIgYIKUEKJSv_QIw6rL9AjhMQAFYAWoHRUNPTk9NWXIGTE5DUzBWCjII1YIBEgQ5MDYyGKUEIMicASjItf0CMIG3_QI4TEABWAFqB0VDT05PTVlyBkxOQ1MwVhIKCAEQARgBKgJVQRgBIgQIARABKAIoAygEMAE) ## Find the cheapest month to fly from Istanbul (IST) to Panama City (PTY) ### November is typically the cheapest month to fly From £618 - £1,192 per traveller. ## Alternative airports near Panama City Prices were available within the past 7 days. Prices and availability are subject to change. [](https://www.expedia.co.uk/Flights-Search?leg1=from:SAW,to:PTY,departure:12/11/2025TANYT&leg2=from:PTY,to:SAW,departure:19/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) PTY Tocumen Intl. Cheapest 16 min [Flights from £845](https://www.expedia.co.uk/Flights-Search?leg1=from:SAW,to:PTY,departure:12/11/2025TANYT&leg2=from:PTY,to:SAW,departure:19/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&sortOrder=INCREASING&sortType=PRICE) Flight from Istanbul to Panama City route information | Origin airport | Istanbul | | --- | --- | | Destination airport | Tocumen Intl. | | Airlines serving | Air Europa, Air France, Delta, KLM, Turkish Airlines, United | | Return price | £694 | | Distance | 10756 km | | Average flight time | 8 hours 12 mins | ## Compare flights from Istanbul to Panama City easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Istanbul to Panama City. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Tocumen Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Istanbul to Tocumen Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Istanbul (IST) to Tocumen Intl. (PTY) The easiest way to view the best deals on flights from Istanbul to Panama City today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Istanbul to Tocumen Intl. start at just £695 and range up to £976.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Istanbul and Panama City - booking your flight during February, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Istanbul to Panama City flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Istanbul to Tocumen Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Frequently asked questions ### How much is a flight from IST to PTY? > Based on fares listed within the last 7 days on Expedia for flights departing within the next year, round-trip flights between Istanbul Airport and Panama Airport start from £695. Book ASAP to score the best price for your exciting adventure. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Istanbul Airport to PTY? > Most flights can be cancelled online, but each air carrier has different terms and conditions. If you do have to cancel your flight, visit our [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033) and follow the instructions. ### Can I fly from IST to PTY right now? > To see what travel restrictions and quarantine requirements are in place for different citizens flying from IST to Panama Airport please visit our [COVID 19 travel advisor portal link](https://www.expedia.co.uk/lp/b/travel-advisor). ### How do I find cheap flights from Istanbul Airport to PTY that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Istanbul Airport to Tocumen Intl. Airport (PTY) flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from IST to PTY? > With around 10,800 kilometres separating Arnavutkoy and Tocumen, your flight will be a long one. Pack wisely to make your time on board more comfortable. Little things like warm clothes and a good travel pillow can make a big difference. ### Which airlines fly direct from Istanbul Airport to PTY? > Unfortunately, there aren't any airlines that directly fly between IST and PTY. You'll need to book a flight with at least one stop. ### Are IST to Panama Airport flight tickets cheaper when they're purchased at the last minute? > Flight prices from IST to Tocumen Intl. Airport (PTY) are available up to 12 months prior to departure on Expedia. And although you may occasionally nab a fantastic last-minute deal, it's not something you should count on. Also, booking your flights ahead of time means you'll have more options — and you can avoid getting trapped in the dreaded middle seat! We're always updating our fares to bring you the biggest bargains, so keep checking in for all the latest specials. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Other ### Accommodation - [Don Bosco Hotels](https://www.expedia.co.uk/Don-Bosco-Panama-City-Hotels.0-n829297665731731456-0.Travel-Guide-Filter-Hotels) - [Las Mañanitas Hotels](https://www.expedia.co.uk/Las-Mananitas-Hotels.d829297652521791488.Travel-Guide-Hotels) - [Tocumen Hotels](https://www.expedia.co.uk/Tocumen-Hotels.d6053184.Travel-Guide-Hotels) ### Flights - [Flights to Tocumen](https://www.expedia.co.uk/Cheap-Flights-To-Tocumen.d6053184.Travel-Guide-Flights) - [Flights from Agen (AGF) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/agf/pac/agen-to-panama-city) - [Flights from Barcelona (BCN) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bcn/pac/barcelona-to-panama-city) - [Flights from Bilbao (BIO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bio/pac/bilbao-to-panama-city) - [Flights from Bocas del Toro (BOC) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/boc/pac/bocas-del-toro-to-panama-city) - [Flights from Boston (BOS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bos/pac/boston-to-panama-city) - [Flights from Belize City (BZE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bze/pac/belize-city-to-panama-city) - [Flights from Columbia (CAE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cae/pac/columbia-to-panama-city) - [Flights from Paris (CDG) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cdg/pac/paris-to-panama-city) - [Flights from Waco Kungo (CEO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ceo/pac/waco-kungo-to-panama-city) - [Flights from Christchurch (CHC) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/chc/pac/christchurch-to-panama-city) - [Flights from Changuinola (CHX) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/chx/pac/changuinola-to-panama-city) - [Flights from Cali (CLO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/clo/pac/cali-to-panama-city) - [Flights from Ciudad Del Carmen (CME) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cme/pac/ciudad-del-carmen-to-panama-city) - [Flights from Chambery (CMF) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cmf/pac/chambery-to-panama-city) - [Flights from Chi Mei (CMJ) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cmj/pac/chi-mei-to-panama-city) - [Flights from Cartagena (CTG) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ctg/pac/cartagena-to-panama-city) - [Flights from Cincinnati (CVG) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cvg/pac/cincinnati-to-panama-city) - [Flights from David (DAV) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/dav/pac/david-to-panama-city) - [Flights from Delhi (DEL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/del/pac/delhi-to-panama-city) - [Flights from Durban (DUR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/dur/pac/durban-to-panama-city) - [Flights from Dubai (DXB) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/dxb/pac/dubai-to-panama-city) - [Flights from Enniskillen (ENK) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/enk/pac/enniskillen-to-panama-city) - [Flights from Medellin (EOH) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/eoh/pac/medellin-to-panama-city) - [Flights from Fort-de-France (FDF) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/fdf/pac/fort-de-france-to-panama-city) - [Flights from Memmingen (FMM) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/fmm/pac/memmingen-to-panama-city) - [Flights from La Fortuna (FON) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/fon/pac/la-fortuna-to-panama-city) - [Flights from Frankfurt (FRA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/fra/pac/frankfurt-to-panama-city) - [Flights from Winter Haven (GIF) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gif/pac/winter-haven-to-panama-city) - [Flights from Glasgow (GLA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gla/pac/glasgow-to-panama-city) - [Flights from Guatemala City (GUA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gua/pac/guatemala-city-to-panama-city) - [Flights from Guayaquil (GYE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gye/pac/guayaquil-to-panama-city) - [Flights from Hong Kong (HKG) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/hkg/pac/hong-kong-to-panama-city) - [Flights from Hof (HOQ) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/hoq/pac/hof-to-panama-city) - [Flights from Houston (HOU) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/hou/pac/houston-to-panama-city) - [Flights from Washington (IAD) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/iad/pac/washington-to-panama-city) - [Flights from Chigorodo (IGO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/igo/pac/chigorodo-to-panama-city) - [Flights from Qingyang (IQN) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/iqn/pac/qingyang-to-panama-city) - [Flights from Istanbul (IST) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ist/pac/istanbul-to-panama-city) - [Flights from Jacksonville (JAX) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/jax/pac/jacksonville-to-panama-city) - [Flights from Jabalpur (JLR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/jlr/pac/jabalpur-to-panama-city) - [Flights from Kitadaito (KTD) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ktd/pac/kitadaito-to-panama-city) - [Flights from Kota (KTU) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ktu/pac/kota-to-panama-city) - [Flights from La Paz (LAP) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lap/pac/la-paz-to-panama-city) - [Flights from Las Vegas (LAS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/las/pac/las-vegas-to-panama-city) - [Flights from Los Angeles (LAX) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lax/pac/los-angeles-to-panama-city) - [Flights from London (LHR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lhr/pac/london-to-panama-city) - [Flights from Liberia (LIR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lir/pac/liberia-to-panama-city) - [Flights from London (LON) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lon/pac/london-to-panama-city) - [Flights from Matamoros (MAM) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mam/pac/matamoros-to-panama-city) - [Flights from Orlando (MCO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mco/pac/orlando-to-panama-city) - [Flights from Medellín (MDE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mde/pac/medellin-to-panama-city) - [Flights from Managua (MGA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mga/pac/managua-to-panama-city) - [Flights from Milford (MLF) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mlf/pac/milford-to-panama-city) - [Flights from Mamfe (MMF) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mmf/pac/mamfe-to-panama-city) - [Flights from Nairobi (NBO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/nbo/pac/nairobi-to-panama-city) - [Flights from Nice (NCE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/nce/pac/nice-to-panama-city) - [Flights from Newcastle (NCL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ncl/pac/newcastle-to-panama-city) - [Flights from Paris (ORY) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ory/pac/paris-to-panama-city) - [Flights from Para Chinar (PAJ) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/paj/pac/para-chinar-to-panama-city) - [Flights from Puebla (PBC) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/pbc/pac/puebla-to-panama-city) - [Flights from Puerto Barrios (PBR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/pbr/pac/puerto-barrios-to-panama-city) - [Flights from Philadelphia (PHL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/phl/pac/philadelphia-to-panama-city) - [Flights from Phoenix (PHX) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/phx/pac/phoenix-to-panama-city) - [Flights from Poitiers (PIS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/pis/pac/poitiers-to-panama-city) - [Flights from Ponce (PSE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/pse/pac/ponce-to-panama-city) - [Flights from Pointe-a-Pitre (PTP) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ptp/pac/pointe-a-pitre-to-panama-city) - [Flights from Panama City (PTY) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/pty/pac/panama-city-to-panama-city) - [Flights from Porto Velho (PVH) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/pvh/pac/porto-velho-to-panama-city) - [Flights from Puerto Vallarta (PVR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/pvr/pac/puerto-vallarta-to-panama-city) - [Flights from Rio Hato (RIH) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/rih/pac/rio-hato-to-panama-city) - [Flights from San Salvador (SAL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sal/pac/san-salvador-to-panama-city) - [Flights from San Antonio (SAT) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sat/pac/san-antonio-to-panama-city) - [Flights from Savannah (SAV) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sav/pac/savannah-to-panama-city) - [Flights from Santo Domingo (SDQ) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sdq/pac/santo-domingo-to-panama-city) - [Flights from San Francisco (SFO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sfo/pac/san-francisco-to-panama-city) - [Flights from San José (SJO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sjo/pac/san-jose-to-panama-city) - [Flights from San Juan (SJU) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sju/pac/san-juan-to-panama-city) - [Flights from Springfield (SPI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/spi/pac/springfield-to-panama-city) - [Flights from Santiago (STI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sti/pac/santiago-to-panama-city) - [Flights from Stuttgart (STR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/str/pac/stuttgart-to-panama-city) - [Flights from Stillwater (SWO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/swo/pac/stillwater-to-panama-city) - [Flights from Sydney (SYD) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/syd/pac/sydney-to-panama-city) - [Flights from Syracuse (SYR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/syr/pac/syracuse-to-panama-city) - [Flights from Trinidad (TAD) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tad/pac/trinidad-to-panama-city) - [Flights from Tapachula (TAP) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tap/pac/tapachula-to-panama-city) - [Flights from Tampa (TPA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tpa/pac/tampa-to-panama-city) - [Flights from Tulcan (TUA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tua/pac/tulcan-to-panama-city) - [Flights from Uberlandia (UDI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/udi/pac/uberlandia-to-panama-city) - [Flights from Fort Walton Beach (VPS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/vps/pac/fort-walton-beach-to-panama-city) - [Flights from Yecheon (YEC) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/yec/pac/yecheon-to-panama-city) - [Flights from Owen Sound (YOS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/yos/pac/owen-sound-to-panama-city) - [Flights from Québec (YQB) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/yqb/pac/quebec-to-panama-city) - [Flights from Manzanillo (ZLO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/zlo/pac/manzanillo-to-panama-city) - [Flights from Zürich (ZRH) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/zrh/pac/zurich-to-panama-city) ### Packages - [Visit Tocumen](https://www.expedia.co.uk/Tocumen.dx6053184) ### Other - [Things to do in Tocumen](https://www.expedia.co.uk/Things-To-Do-In-Tocumen.d6053184.Travel-Guide-Activities) \*Available to Expedia members.