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£425 Cheap Flights from New Orleans (MSY) to Panama City (PTY)

View £425 flight on Wed, 9 Sept 2026Opens in a new window

Popular airlines from Louis Armstrong New Orleans Intl. Airport (MSY) to Tocumen Intl. Airport (PTY)

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Cheap Flights from New Orleans (MSY) to Panama City (PTY)

Prices were available within the past 7 days and start at £425 for one-way flights and £647 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

JetBlue Airways
Wed, 9 Sept - Sat, 12 Sept
MSY
New Orleans
PTY
Panama City
£647 Return, found 4 days ago
£647
Return
found 4 days ago
Select JetBlue Airways flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Sat, 12 Sept, priced at £647 found 4 days ago
JetBlue Airways
Wed, 9 Sept - Sat, 12 Sept
MSY
New Orleans
PTY
Panama City
£654 Return, found 4 days ago
£654
Return
found 4 days ago
Select JetBlue Airways flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Sat, 12 Sept, priced at £654 found 4 days ago
JetBlue Airways
Wed, 9 Sept - Fri, 11 Sept
MSY
New Orleans
PTY
Panama City
£659 Return, found 4 days ago
£659
Return
found 4 days ago
Select JetBlue Airways flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Fri, 11 Sept, priced at £659 found 4 days ago
JetBlue Airways
Wed, 9 Sept - Fri, 11 Sept
MSY
New Orleans
PTY
Panama City
£663 Return, found 4 days ago
£663
Return
found 4 days ago
Select JetBlue Airways flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Fri, 11 Sept, priced at £663 found 4 days ago
JetBlue Airways
Wed, 9 Sept - Fri, 11 Sept
MSY
New Orleans
PTY
Panama City
£668 Return, found 4 days ago
£668
Return
found 4 days ago
Select JetBlue Airways flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Fri, 11 Sept, priced at £668 found 4 days ago
Air Canada
Wed, 9 Sept - Sat, 12 Sept
MSY
New Orleans
PTY
Panama City
£720 Return, found 4 days ago
£720
Return
found 4 days ago
Select Air Canada flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Sat, 12 Sept, priced at £720 found 4 days ago
Air Canada
Wed, 9 Sept - Sat, 12 Sept
MSY
New Orleans
PTY
Panama City
£728 Return, found 4 days ago
£728
Return
found 4 days ago
Select Air Canada flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Sat, 12 Sept, priced at £728 found 4 days ago
JetBlue Airways
Wed, 9 Sept - Sat, 12 Sept
MSY
New Orleans
PTY
Panama City
£729 Return, found 4 days ago
£729
Return
found 4 days ago
Select JetBlue Airways flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Sat, 12 Sept, priced at £729 found 4 days ago
JetBlue Airways
Wed, 9 Sept - Fri, 11 Sept
MSY
New Orleans
PTY
Panama City
£746 Return, found 4 days ago
£746
Return
found 4 days ago
Select JetBlue Airways flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Fri, 11 Sept, priced at £746 found 4 days ago
Air Canada
Wed, 9 Sept - Sat, 12 Sept
MSY
New Orleans
PTY
Panama City
£758 Return, found 4 days ago
£758
Return
found 4 days ago
Select Air Canada flight, departing Wed, 9 Sept from New Orleans to Panama City, returning Sat, 12 Sept, priced at £758 found 4 days ago

Find the cheapest month to fly from New Orleans (MSY) to Panama City (PTY)

January is typically the cheapest month to fly

From £432 - £561 per traveller.

Frequently asked questions

How much does a flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) cost?
You can find one-way and return flights from MSY to PTY with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when MSY to PTY ticket fares go up or down.
What is the cheapest month to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
If you're looking for the cheapest time to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.), September is typically your best bet. You can expect average return fares around £307 during this month. September often sees lower prices because it falls outside of peak holiday seasons, when demand for travel tends to decrease. Other budget-friendly months to consider for this route include April and June.
Which airlines fly direct from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
Enter MSY to PTY and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
JetBlue Airways is one of the cheapest airlines offering connecting return flights from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.), with prices starting from around £424 for flights that can be booked for departure within the next year. These flights typically include a layover in John F. Kennedy Intl. (JFK). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
To find a cheap flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
The best time to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) is typically September or April. These months offer a great balance, with average return flight prices around £307. While these months are the cheapest, they also tend to be popular times to travel, meaning you'll likely find plenty of flight options to suit your schedule. If you're flexible, these months give you both affordable fares and excellent flight schedules to work with.
How many flights per day from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
There are approximately 36 connecting flights per day from Louis Armstrong New Orleans Intl. (MSY) to Tocumen Intl. (PTY). Some common connection points include George Bush Intercontinental (IAH), John F. Kennedy Intl. (JFK), and Fort Lauderdale - Hollywood Intl. (FLL).
What is the earliest flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
The earliest flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) typically departs around 5:00 AM. This service is seasonal, active only in April, and is operated by United and Avianca. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
You'll find the most flights from Louis Armstrong New Orleans Intl. (MSY) to Tocumen Intl. (PTY) on a Thursday, with around 28 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include United, Delta, and American Airlines. Flight schedules are fairly consistent throughout the week, with Thursday offering only slightly more flights than other days.
What are the most popular departure times for flights from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
The most popular departure times for flights from Louis Armstrong New Orleans Intl. (MSY) to Tocumen Intl. (PTY) are in the early morning, from 6am to 9am. Many major carriers, including United, American Airlines and Delta, offer flights during this window. Many travellers prefer these times as they allow for an early start to your journey and often mean you can arrive at your destination with plenty of time to settle in.
How long does it take to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
There are no nonstop flights from Louis Armstrong New Orleans Intl. (MSY) to Tocumen Intl. (PTY). The distance between these two airports is approximately 2,586 kilometres. Flights with one stop typically take around 6 hours 48 minutes. If you opt for flights with two or more stops, your travel time will be longer, usually around 22 hours 30 minutes. Keep in mind that actual flight times can vary due to factors like routing, weather, and wind patterns.
Can you fly business or first class from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
Yes, you can fly business class from MSY to PTY. You can fly business class with Air Canada and Delta.
How do I earn miles on a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) flight with Expedia?
It's easy to earn miles on a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Panama City (PTY) from New Orleans, LA (MSY)?
If you're planning to travel to Panama City from Louis Armstrong New Orleans Intl. (MSY), you can fly directly into Tocumen Intl. (PTY). Some flights may connect through major hubs like George Bush Intercontinental (IAH), Hartsfield-Jackson Atlanta Intl. (ATL), or Charlotte-Douglas Intl. (CLT) before reaching Panama City. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) at the last minute?
Typically, booking a last minute flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) flight and hotel package?
Securing a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.)?
If you booked your New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Panama City (PTY-Tocumen Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Louis Armstrong New Orleans Intl.
Destination airport
Tocumen Intl.
Roundtrip price
£646
Distance
2570 km

Book with confidence

Compare flights from New Orleans to Panama City easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from New Orleans to Panama City. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Tocumen Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Louis Armstrong New Orleans Intl. to Tocumen Intl..  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Louis Armstrong New Orleans Intl. (MSY) to Tocumen Intl. (PTY)

The easiest way to view the best deals on flights from New Orleans to Panama City today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Louis Armstrong New Orleans Intl. to Tocumen Intl. start at just £647 and range up to £1,630.  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near New Orleans and Panama City
  • booking your flight during September, the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your New Orleans to Panama City flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Louis Armstrong New Orleans Intl. to Tocumen Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from New Orleans to Panama City easily and book with confidence

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*Available to Expedia members.