Santa Margarita Holidays from £579

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Top Santa Margarita Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Sideways Inn

Sideways Inn

£579
per person
24 Sept - 29 Sept
found 1 day ago
Return direct flight included
New York (NYC) to San Luis Obispo (SBP)
9/10 Wonderful! (1,701 reviews)
Sideways inn was really great thanks again 😊

Reviewed on 11 Aug 2026

Santa Margarita Essential Information

Language
English
Currency
U.S dollars
Population
1,250
Max Temp Winter
18ºC
Max Temp Summer
27ºC

Top hotels in Santa Margarita

Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo

1631 Monterey St San Luis Obispo CA
Fully refundable
£129
7 Sept - 8 Sept
includes taxes & fees
9.4/10 Exceptional! (1,525 reviews)
"Great experience. Surpassed expectations. Room very clean and spacious. Pretty grounds that were also well maintained. Front desk staff friendly and helpful. Will definitely be back next time we’re in SLO."

Reviewed on 11 Aug 2026

Quality Suites Downtown San Luis Obispo
Spyglass Inn

Spyglass Inn

2705 Spyglass Dr Pismo Beach CA
Fully refundableReserve now, pay when you stay
£136
3 Sept - 4 Sept
includes taxes & fees
Spyglass Inn
Pacific Point Resort

Pacific Point Resort

2555 Price Street Pismo Beach CA
Fully refundableReserve now, pay when you stay
£189
8 Sept - 9 Sept
includes taxes & fees
Pacific Point Resort
See all 2,315 properties in Santa Margarita
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Margarita attractions

Santa Margarita Lake

6.0/10 (1 review)
This pristine drinking water reservoir offers boating, fishing, and hiking through oak woodlands. Reserve a campsite to experience starlit nights and morning mists rising off the tranquil waters.
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Pozo Saloon

This historic stagecoach stop from 1858 has transformed into a rustic music venue hosting legends like Willie Nelson. Savour famous burgers with cold beer in mason jars while enjoying the Old West atmosphere.
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Soda Lake

9.4/10 (23 reviews)
This striking alkali wetland transforms into dazzling white salt flats as its waters evaporate. Capture stunning photos from the Soft drink Lake Overlook trail, especially magical during spring wildflower blooms.
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Ancient Peaks Winery

8.0/10 (11 reviews)
You can enjoy a tasting or tour at Ancient Peaks Winery during your travels to Santa Margarita. Visit the top-notch restaurants or wineries in this family-friendly area.
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What to do in Santa Margarita

 San Luis Obispo Self Guide Walking Tour

San Luis Obispo: GPS-Guided Walking Audio Tour Via App

£8
per traveller
San Luis Obispo: GPS-Guided Walking Audio Tour Via App
Scenic Sidecar Vineyard Adventure San Luis Obispo

Scenic Vineyard Tour Adventure San Luis Obispo

£34
per adult
100% of travellers recommend
Scenic Vineyard Tour Adventure San Luis Obispo
The Fremont Theatre is one of the last Streamline Moderne building in existence.

Essential Downtown SLO: A Self-Guided Audio Tour

£8
per adult
Essential Downtown SLO: A Self-Guided Audio Tour
See all activities in Santa Margarita

Frequently asked questions

Why should I book my Santa Margarita holiday with Expedia?
Expedia has your back for every aspect of your next Santa Margarita holiday. You'll always land the best deals around, but when you bundle your accommodation, airfares and/or hire car into a holiday package, you can save even more. Want to really make the most of your break? Add some fun tours and activities to your customised package. We offer flexible cancellation policies on most bookings, so there's no need to stress if you have to change your plans. Head over to our Customer Service Portal link to learn more.
When is the best time of year to holiday in Santa Margarita?
If you love the excitement that comes with peak season, visit Santa Margarita in March, June and July. If you're looking for a more relaxed vibe, October, November and December will suit you better. Plan your trip to Santa Margarita according to what type of adventure you want. December is the coolest month, when daytime temperatures average 10ºC. In July, the warmest month, you will experience temperatures of around 21ºC during the day.
What is the top hotel for my holiday in Santa Margarita?
Sand Pebbles Inn sets the scene for a memorable holiday in Santa Margarita, offering all the conveniences you need and more.
How do I get a cheap holiday to Santa Margarita?
Booking a hotel and flight together with Expedia won't just save valuable time — it'll save you a few pounds too. A Santa Margarita holiday makes it simple to arrange your perfect trip. With more than 400 airlines all over the world to select from, finding convenient flights that fit your busy schedule will be no sweat. On top of that, we have over 321,000 hotels globally to pick from. Now that's what we call choice. No matter who you are, Expedia brings the world within your reach. Learn more about how you can save money on your next holiday when you combine your hotel and flight bookings with Expedia.
What is the best area to stay in when on holiday in Santa Margarita?
Santa Margarita has a number of fascinating places to see, like Carrizo Plain National Monument. Stay someplace close by and make sightseeing easier.
Do I need a visa for my Santa Margarita holiday?
Official government websites have all the information you need on visa requirements, application procedures and any necessary documentation. Your nationality and reason for travelling, whether it be for holidays or work, will determine if you'll need a visa for Santa Margarita. Also be sure that your passport is up to date and has at least six months validity remaining beyond your return date. Do all your travel planning well in advance to avoid any last-minute surprises.
What should I wear on my Santa Margarita holiday?
First, think about the activities planned during your holiday in Santa Margarita and take versatile pieces that you can easily mix and match. For fashion inspiration or information on any dress codes, browse style blogs or relevant social media accounts. Be sure to look at the weather forecast so you can pack appropriately. The warmest time of year in Santa Margarita is July, with average daily temperatures of 21ºC. If you're visiting during the coolest month of December, the mercury averages 10ºC during the day.
What does an Expedia Santa Margarita holiday include?
Hotels, hire cars and flights — we've got them all. With Expedia, you can shape your Santa Margarita travel package the way you like it. All you have to do is figure out what you need. Once you've made your booking, why not add fun things like experiences and activities? The more you bundle, the greater the savings! Expedia features different kinds of properties, with the most sought after in Santa Margarita including private holiday homes and agritourism properties. With Expedia, you can expect the flexibility and freedom to design your dream escape your way.
Does Expedia offer Book Now, Pay Later Santa Margarita holidays?
Your bank balance shouldn't prevent you from going on holiday, so Expedia has come up with a solution to help. Now that we've formed a partnership with online lender Klarna, it's easier than ever to book a dream getaway without using up all your savings. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your trip. Check out these flexible payment options:
  • Pay monthly holidays: Klarna offers manageable monthly payment plans that work for all budget sizes, so you can jet away on that well-deserved holiday sooner.
  • No-deposit holidays: When you stumble on an amazing deal but your budget doesn't quite cover it yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to secure your getaway.
Can I choose my airline with a Santa Margarita Expedia holiday?
Yes — and it's simple too. Expedia has access to more than 400 partner airlines worldwide. Our packages give you the freedom to take your pick of available flights, hotels and activities that suit you.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.