Santa Cruz adults only hotels from £34

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Top Adults only hotels in Santa Cruz

Swissôtel Santa Cruz De La Sierra
4.5 out of 5
5to anillo Avenida La Salle # 4500, Santa Cruz
The price is £77 per night from 23 Aug to 24 Aug
£77
23 Aug - 24 Aug
9.2/10 Wonderful! (77 reviews)
Great night at the Swissotel
"It was a great one-night stay at the Santa Cruz Swissôtel. The hotel was impecable, service excellent, and the staff very friendly and professional. We shall return to this hotel in the future."

Reviewed on 14 Jul 2025

Swissôtel Santa Cruz De La Sierra
Novotel Santa Cruz De La Sierra
5 out of 5
AV ROCA CORONADO 901, ENTRE TERCER Y CUARTO ANILLO, Santa Cruz
The price is £93 per night from 23 Aug to 24 Aug
£93
23 Aug - 24 Aug
9/10 Wonderful! (95 reviews)
"The best place , best workers"

Reviewed on 20 Apr 2025

Novotel Santa Cruz De La Sierra
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 out of 5
San Martin Avenue Esq Street E - E, Santa Cruz
The price is £77 per night from 21 Aug to 22 Aug
£77
21 Aug - 22 Aug
9/10 Wonderful! (248 reviews)
"Nice hotel"

Reviewed on 15 Aug 2025

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hotel Cortez
3.5 out of 5
Av. Cristobal de Mendoza 280, Santa Cruz
The price is £85 per night from 24 Aug to 25 Aug
£85
24 Aug - 25 Aug
9/10 Wonderful! (111 reviews)
"The staff and property are second to none!"

Reviewed on 14 Jun 2025

Hotel Cortez
Marriott Santa Cruz de la Sierra Hotel
5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is £88 per night from 29 Aug to 30 Aug
£88
29 Aug - 30 Aug
9/10 Wonderful! (191 reviews)
"all"

Reviewed on 5 Jun 2025

Marriott Santa Cruz de la Sierra Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 out of 5
Ave. San Martin, #455, Santa Cruz
The price is £97 per night from 9 Sept to 10 Sept
£97
9 Sept - 10 Sept
8.8/10 Excellent! (322 reviews)
"Always an amazing hotel"

Reviewed on 21 Jun 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Camino Real Hotel
4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
The price is £104 per night from 15 Sept to 16 Sept
£104
15 Sept - 16 Sept
8.8/10 Excellent! (396 reviews)
Best amenities
"Best amenities in a hotel , but need some upgrades"

Reviewed on 16 Jul 2025

Camino Real Hotel
Sun Hotel
3.5 out of 5
Av. Banzer Km 13, Aeropuerto Internacional Viru Viru, Santa Cruz, Santa Cruz
8.2/10 Very Good! (310 reviews)
"Staff are friendly and helpful! Great landing spot after a long flight (it’s just 5 mins from airport)."

Reviewed on 7 Jul 2025

Sun Hotel
Terranova Suites
3.5 out of 5
7º Anillo 400 mts al Oeste de, Av. Cristo Redentor, Santa Cruz, Santa Cruz
The price is £34 per night from 21 Aug to 22 Aug
£34
21 Aug - 22 Aug
7.8/10 Good! (90 reviews)
"Easy to access"

Reviewed on 14 Apr 2025

Terranova Suites
Hotel LP Santa Cruz Centro
3 out of 5
Av.Ejercito Nacional 290, (frente Stadium Tahuichi), Santa Cruz
7.8/10 Good! (280 reviews)
"Clean, friendly staff"

Reviewed on 2 Jun 2024

Hotel LP Santa Cruz Centro
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find Romantic Hotels in Santa Cruz

Buganvillas Hotel Suites & Spa

Buganvillas Hotel Suites & Spa

Av. Roca y Coronado No. 901, Santa Cruz
7.4/10 Good! (92 reviews)

Frequently Asked Questions

How can I find the best adults only resorts in Santa Cruz?

The best adults only resort for you is deeply personal. First off, decide what you want from your dream holiday, then use our filters to bring it to life. Find resorts with hot tubs, spas and incredible views, then check out the reviews to see how other guests enjoyed their stay.

How much does a Santa Cruz adults-only hotel cost?

With Expedia, you can find adults only hotels from £34 to per night. Prices and availability are subject to change. Additional terms may apply.

How can I find an adults only all-inclusive holiday in Santa Cruz?

It’s simple. Just select the all-inclusive filter to find the best resorts where you can eat, drink and holiday to your heart’s content.

What can I expect from Santa Cruz 5-star all-inclusive adults only hotels?

Luxury comes as standard in the 5-star resorts of Santa Cruz. Step into spotless surroundings, stellar service and all the amenities your heart desires, from spas and pools to casinos and cocktail bars.

Why should I book a Santa Cruz adults only hotel with entertainment?

When you book an adult only hotel with entertainment, pack your bags to get dolled up for the very best of comedy, cabaret, music, magic and much more – all just steps from your room.

How can I find the best deals on adults only resorts in Santa Cruz?

To find amazing deals in Santa Cruz and for a quieter experience, book your holiday in . The more flexible you can be with your dates, the better your chances are of getting a fantastic wallet-friendly deal. You can always check out our latest cheap deals for a little inspiration.

Do adults only hotels in Santa Cruz offer free cancellation?

Some adults only hotels here offer free cancellation. Some don’t. It’s always best to check before you book. You can filter by free cancellation and pay later options to find resorts with that extra flexibility you want.

Why should I book my adults only resort in Santa Cruz with Expedia?

At Expedia, we put everything you need to book your dream trip in one place. With a vast selection of incredible adult only accommodation at your fingertips, all that’s left to do is set your sights on what’s right for you.