Title: The Best Hotels in Santa Ana, Panama City - 2025 Updated Prices | Expedia.co.uk [Santa Ana Travel Guide](https://expedia.co.uk/Panama-City-Santa-Ana.dx553248623199107606)[Holiday Rentals in Panama City](https://expedia.co.uk/Panama-City-Holiday-Rentals.d2897.Travel-Guide-HolidayRentals)[Flights to Panama City](https://expedia.co.uk/Cheap-Flights-To-Panama-City.d2897.Travel-Guide-Flights)[Things to do in Panama City](https://expedia.co.uk/Things-To-Do-In-Panama-City.d2897.Travel-Guide-Activities)[Santa Ana Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Ana.d553248623199107606.Car-Hire-Guide)[Santa Ana Holidays](https://expedia.co.uk/Santa-Ana.d553248623199107606.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Santa Ana, Panama City ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Ana Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&lodging=APART_HOTEL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&lodging=APARTMENT) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&amenities=POOL) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&amenities=OCEAN_VIEW) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&amenities=PETS) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Ana%2C+Panama+City%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248623199107606&latLong=8.956329%2C-79.541337&adults=2&startDate=2025-10-25&d1=2025-10-25&endDate=2025-10-27&d2=2025-10-27&lodging=CONDO) ## Check prices for these dates Tonight [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248623199107606&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248623199107606&startDate=2025-10-12&endDate=2025-10-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248623199107606&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248623199107606&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Top Trending Hotels Near Santa Ana, Panama City ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Private kitchen | Fridge, microwave, oven, electric kettle](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/041fa75e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Duplex | Living area | Smart TV](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/32dc2d2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/42c91f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments Santa Ana 9.4/10 Exceptional (48) "Great stay, would recommend." [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/9363bddf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | View from room](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/77400971.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/946c31e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, soundproofing, free WiFi](https://images.trvl-media.com/lodging/4000000/3260000/3257600/3257592/6401edce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel República Santa Ana 6.6/10 (176) "Fantastic customer service" [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/a4e5c85a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/6917aaca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/f0903154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89840000/89836900/89836824/67d4e119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ART CASCO The Hotel Santa Ana 6.6/10 (8) "Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best" [](https://www.expedia.co.uk/Panama-City-Hotels-ART-CASCO-The-Hotel.h89836824.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/4a38aa01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/67140443.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Double Bed | Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/132a0077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/88000000/87400000/87396800/87396713/83a1ee2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hostal La Cigarra Santa Ana 7.4/10 Good (53) "Helpful staff, secure, close to sights" [](https://www.expedia.co.uk/Panama-City-Hotels-Hostal-La-Cigarra.h87396713.Hotel-Information) ![Single Room | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/90000000/89150000/89148300/89148227/df04c1c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/90000000/89150000/89148300/89148227/cd9ccafe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Quadruple Room, 2 Double Beds | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/90000000/89150000/89148300/89148227/28308f03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Triple Room | Bathroom](https://images.trvl-media.com/lodging/90000000/89150000/89148300/89148227/fc44afbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riazor Santa Ana 3.8/10 (11) "Rough neighborhood " [](https://www.expedia.co.uk/Panama-City-Hotels-JOSE-PEREZ-PINAL.h89148227.Hotel-Information) ![Apartment (20) | 1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/dacdb94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (09) | Private kitchen | Fridge, microwave, stovetop, toaster](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/f1ebeb16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/7977bbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Apartment | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/bc995ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Manzana by Wynwood House Santa Ana 7.0/10 Good (14) "Great hotel. Very close to Casco viejo" £50 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) ![Room, Multiple Bedrooms, Accessible, Smoking | Pool | Outdoor pool](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/b9369105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Lounge](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/141773b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Fitness studio](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/w2048h1361x0y0-8b7f1fa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Bedrooms, Accessible, Smoking | Living room | Books](https://images.trvl-media.com/lodging/113000000/112910000/112906600/112906538/w2048h1361x0y0-35b02ec8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Room-sofa Bed Stay Rooftop Pool & Gym, A Santa Ana 2.0/10 (1) "You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money" £121 includes taxes & fees 29 Oct - 30 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Room-In-Guest-Room-Sofa.h112906538.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/da7a9306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/3873c049.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG 13.1 mi from Santa Ana 8.4/10 Very good (2237) "near airport, staff super helpful " £89 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![47-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed, Jetted Tub | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/09deaa1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed | 1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/58d3a2eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/174f9ccc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Hotel Panama Casco Viejo San Felipe, 0.5 mi from Santa Ana 9.0/10 Wonderful (1002) "Very beautiful hotel with helpful staff. Very good dining options. " £127 includes taxes & fees 27 Oct - 28 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Exclusive House | Terrace/patio](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/e71bb101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/f174b378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/3645c5b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![San Felipe Junior Suite, 1 Double bed or 2 Single Beds | 3 bedrooms, Egyptian cotton sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/18000000/17390000/17380200/17380132/4964bad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Concordia Boutique Hotel San Felipe, 0.3 mi from Santa Ana 9.4/10 Exceptional (184) "Beautiful boutique hotel. Our room was large, bed is comfortable, nice selection of pillows, large balcony. Hotel staff is friendly and helpful. I highly recommend this place." [](https://www.expedia.co.uk/Panama-City-Hotels-La-Concordia-Boutique-Hotel.h17380132.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/42ee64f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 2 Double Beds | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/12f18f65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/de49bf58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:30 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/4000000/3900000/3893100/3893051/dd414168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Coral Suites El Cangrejo, 2.3 mi from Santa Ana 9.0/10 Wonderful (1004) "Great location with spacious rooms " £57 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Coral-Suites.h3893051.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/c8749fd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (PAB 14 per person)](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/aed99723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 2 Double Beds, Non Smoking (TRYP) | 1 bedroom, in-room safe, individually furnished, desk](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/e150b6c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/6000000/5310000/5309200/5309170/86d63ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TRYP by Wyndham Panamá Centro El Cangrejo, 2.2 mi from Santa Ana 9.0/10 Wonderful (1010) "Staff was very friendly and breakfast option were wide" £67 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-TRYP-By-Wyndham-Panama-Centro.h5309170.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down duvets, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/533cc611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/ea26a97c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/d73825f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino 12.3 mi from Santa Ana 8.6/10 Excellent (1901) "Nice hotel, close to the airport, friendly staff" £157 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/67639d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Penthouse (In the heart of the City) | 1 bedroom, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/c6c3b77c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/ec5ee8cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Riu Plaza Panama Campo Alegre, 2.2 mi from Santa Ana 9.0/10 Wonderful (4375) "Clean room, friend staff, breakfast options were great" £98 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4e8feb51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/ae55473e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Double Room | 1 bedroom, premium bedding, down duvets, free minibar](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/7ab63fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá Punta Paitilla, 2.2 mi from Santa Ana 8.4/10 Very good (1117) "Great place " £106 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/31f2cc22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/a9995668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/cecfcd5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Principe Hotel and Suites El Cangrejo, 2.4 mi from Santa Ana 9.0/10 Wonderful (1506) "Great place to stay" £42 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/f988dfaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/b119cb62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/a2ab1d01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Novotel Panama City El Cangrejo, 2.7 mi from Santa Ana 9.0/10 Wonderful (1016) "Room was always well attended to staff was very friendly and kind breakfast was gd 💕" £80 includes taxes & fees 7 Nov - 8 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/7c4bef31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/14f91618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/675171b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/920000/917800/917774/73e2776d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hospedium Princess Hotel Panama Obarrio, 2.3 mi from Santa Ana 7.6/10 Good (639) "The property itself was clean and felt safe. Convenient location close to different restaurants and ease of transportation options." £44 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Panama-Princess.h917774.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/1700edf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/c4347824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Classic, 1 King Bed, Non-Smoking | Egyptian cotton sheets, premium bedding, pillow-top beds, minibar](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/8ec9f171.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/70000/69700/69638/b594ef85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bristol Panama, a Registry Collection Hotel Campo Alegre, 2 mi from Santa Ana 9.2/10 Wonderful (1007) "We had an amazing time, great hotel and great breakfast. " £154 includes taxes & fees 23 Oct - 24 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Bristol-Panama.h69638.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/3db8be94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/4ac2734a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/91ac7bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Plaza Paitilla Inn Hotel Punta Paitilla, 2.1 mi from Santa Ana 9.4/10 Exceptional (2121) "Stayed 4 nights excellent property and views from the room" £85 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-25&endDate=2025-10-26®ionId=553248623199107606&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Santa Ana Find the best Santa Ana areas for the activities you enjoy most. [Learn more about Santa Ana](https://www.expedia.co.uk/Panama-City-Santa-Ana.dx553248623199107606) - Casco Viejo - Bella Vista - El Cangrejo - San Francisco - Punta Paitilla [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6285189) ![Casco Viejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:w%7Csu%40z%7CmdNsAsJNa%40sCsD%60HKJ%7DFO_Ai%40A%3F%5B%5C%3FBmAXC%7D%40aBd%40yBj%40%3FB%7D%40b%40%40Nl%40t%40I%60%40uA%7C%40D%40r%40%7ECNNm%40%60AIaAAVoCbFdAjB%7B%40pEvAKn%40_J%7CB%3FzDt%40%3FHnDZCKl%40f%40bAq%40r%40GrApAFQrAlBp%40O%7EBgEY%5CrCr%40%5EVxAiSFmDpA&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=uEe2tFISgoY2i6D1L7Cp-Szzr7E=) ### Casco Viejo Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6285189) ![](https://mediaim.expedia.com/destination/1/1916fc53ea2cb142bbaeb7b9e6efaf16.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/d5ab8e549e1cfa831dcb33b7e1b0352d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/919b43d85bf36a400b3c07d30881f725.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/de251296a0096f0bf5fd9914c545600d.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/a8f0f1d663e33ab4f81206a124826dcd.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=3000663485) ![Bella Vista map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ksxu%40xrmdNeY_Ea%60Ach%40wd%40eZ%60AmN%60KeE%7EE%7DIvIw%40bC%7BFvJkEf%40cEx%5BaVbHnA%7CGrN%60HxCfGnFlD_AhLfHlHj%40%60EiErGh%40tIfx%40qFbFoH%7Cc%40aI_BsItR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=kybUo6TOAHV5XfFCWEb1fcek5LQ=) ### Bella Vista Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=3000663485) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6285972) ![El Cangrejo map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Bpzu%40%60xldN%7D%5BcRdDeKmFiDvDaNbCgGxW%7D%40rIrDpFzGvJpGwFlIpFnGg%60%40zR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=TyMwYMNUwH4f3VdmHvCgBWau0RI=) ### El Cangrejo The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6285972) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248623199112076) ![San Francisco map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wr%7Bu%40hdjdNiV%7BDud%40_SiCcEAqJ%7B%40aEkW_Zh%5EeK%7E%40_CWkNbDFxD%7BAgA%7BEqBqDL%7DDwDoKIkCt%40sBsAgAo%40oBvCKhG%7EDhBFh%40i%40%7C%40CxAx%40zCZrEu%40lA%7D%40So%40b%40qChA%7D%40dCAtExD%60DrGvCxArDQMwDvBWl%40y%40rAJo%40w%40z%40_AxCrBtBn%40pEpD%7BBlCmAyAt%40dEb%40Nd%40e%40HaAzBkCnFfDFr%40%7B%40h%40Jr%40pIvFlFdL%7EJlJhM%60SlDPbe%40eBrBlAr%40xAA%60AsAtBaFnBO%60%40p%40bEQtF%60HxAi%40lAIoA%7DEQCXz%40VoATQdAn%40p%40lH%40xBrBh%40xBK%60ArAVh%40%7EAvAd%40jD%7ECXjAYhE%5E%5CdBKnAnA_EzD%7BDp%40kBkAyFy%40qAdAqC%5Ec%40b%40yBYuBXaEtDeFi%40qC%7B%40kHiFgAKgBn%40eAE_ByBuEaDcCk%40kAyA_GuMaDB_DiB_A%7CAsFrB%7D%40jEiGjCeDVQfC%7BBx%40HrB%5DhAsIfEgBbE&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=LnVVpfxBpjhgnoVjOyo-4O6-uto=) ### San Francisco San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248623199112076) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=6285983) ![Punta Paitilla map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Duwu%40rdjdNiAuFgGy%40gEfEcV_JsDpAyBsCzDaDbBgGlGmO%5CiHdFm%40%60IiHvFiA%7CDtP%60W%60KpFzZq%5ExI&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=TYDp5EcfRW6ARRcsV3BbssS7Oco=) ### Punta Paitilla Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=6285983) ## Top Santa Ana Hotel Reviews ![Las Americas Golden Tower Panama](//images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "Wonderful!!!" [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Central Hotel Panama Casco Viejo](//images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg) ### Central Hotel Panama Casco Viejo 10/10 Excellent "Excellent " [](https://expedia.co.uk/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Megapolis Hotel Panamá](//images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg) ### Megapolis Hotel Panamá 10/10 Excellent "Spacious and convenient " [](https://expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![Principe Hotel and Suites](//images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Comfortable and affordable " [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Waymore Hotel Spa & Casino](//images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "I love this hotel, the breakfast is great, the hotel room spacious and clean. Having a Casino and night club right in your hotel is s super plus. The staff is very friendly snd helpful. The maid service is excellent and the room service team is always on point." [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "The experience was very beautiful from the room to the views at the pool. Customer service excellent and respectful and courteous. They made my birthday wonderful." [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](//images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "From greeting at the front, helpful checkin, great service in restaurants to pickup of our luggage when leaving, fabulous" [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Room service and bar food needs to improve" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Didn’t use the gym" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ## Frequently asked questions ### What are the best budget hotels in Santa Ana? > In the heart of Panama City, Hostal La Cigarra offers an inclusive setting that combines traditional design with modern comforts, making it a great choice for budget-conscious travellers. With a customer review rating of 7.4, this hostal is situated near historical districts and shopping areas, allowing families to explore the rich culture and vibrant life of the city. Guests appreciate the complimentary in-room WiFi, making it easy to stay connected while on the go. > > > > For those seeking a luxurious experience without breaking the bank, [Hotel República](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-Republica.h3257592.Hotel-Information) presents a charming option with its rooftop terrace providing partial ocean views, superb for relaxing after a day of adventures. This hotel also features free WiFi and air conditioning, ensuring comfort during your stay. Families can take advantage of the area shuttle service to explore Panama City's attractions conveniently. ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Ana. ### How can I save on a Santa Ana hotel booking with Expedia? > Before booking your Santa Ana hotel, remember to join Expedia's free travel rewards program. Just sign up and sign in to access our lowest Member Prices as well as members-only perks. You could also enjoy savings by bundling together your hotel and flights on Expedia. ### How much is the nightly rate at a Santa Ana hotel? > Hotel prices in Santa Ana often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - [Hotels near Albrook Shopping Mall](https://www.expedia.co.uk/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Hotels near Amador Causeway](https://www.expedia.co.uk/Amador-Causeway-Hotels.0-l6286127-0.Travel-Guide-Filter-Hotels) - [Amador Hotels](https://www.expedia.co.uk/Amador-Panama-City-Hotels.0-n553248635933392377-0.Travel-Guide-Filter-Hotels) - [Hotels near Ancon Hill](https://www.expedia.co.uk/Ancon-Hill-Hotels.0-l6286129-0.Travel-Guide-Filter-Hotels) - [Balboa Hotels](https://www.expedia.co.uk/Balboa-Panama-City-Hotels.0-n6323179-0.Travel-Guide-Filter-Hotels) - [Barrio Chino Hotels](https://www.expedia.co.uk/Barrio-Chino-Panama-City-Hotels.0-n714749931894550528-0.Travel-Guide-Filter-Hotels) - [Bella Vista Hotels](https://www.expedia.co.uk/Bella-Vista-Panama-City-Hotels.0-n3000663485-0.Travel-Guide-Filter-Hotels) - [Calidonia Hotels](https://www.expedia.co.uk/Calidonia-Panama-City-Hotels.0-n3000663488-0.Travel-Guide-Filter-Hotels) - [Campo Alegre Hotels](https://www.expedia.co.uk/Campo-Alegre-Panama-City-Hotels.0-n553248635976397615-0.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Casco Viejo](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels-Boutique-Hotel.0-n6285189-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Casco Viejo](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels-Hilton-Hotels.0-n6285189-0--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Casco Viejo](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels-Historic-Hotel.0-n6285189-0-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Wedding Hotels in Casco Viejo](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels-Wedding-Hotel.0-n6285189-0-tWeddingHotel.Travel-Guide-Filter-Hotels) - [Casco Viejo Hotels](https://www.expedia.co.uk/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels) - [Causeway Islands Hotels](https://www.expedia.co.uk/Causeway-Islands-Hotels.d6336377.Travel-Guide-Hotels) - [Hotels near Cinta Costera](https://www.expedia.co.uk/Cinta-Costera-Hotels.0-l6245970-0.Travel-Guide-Filter-Hotels) - [Curundu Hotels](https://www.expedia.co.uk/Curundu-Panama-City-Hotels.0-n553248623199107736-0.Travel-Guide-Filter-Hotels) - [All-Inclusive Hotels in Panamá Province](https://www.expedia.co.uk/Destinations-In-Panama-Province-All-Inclusive-Hotel.0-0-d6246281-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Gay-Friendly Hotels in Panamá Province](https://www.expedia.co.uk/Destinations-In-Panama-Province-Gay-Friendly-Hotel.0-0-d6246281-tGayFriendlyHotel.Hotel-Filter-Destinations) - [Panamá Province Hotels](https://www.expedia.co.uk/Destinations-In-Panama-Province.d6246281.Hotel-Destinations) - [El Cangrejo Hotels](https://www.expedia.co.uk/El-Cangrejo-Panama-City-Hotels.0-n6285972-0.Travel-Guide-Filter-Hotels) - [El Chorrillo Hotels](https://www.expedia.co.uk/El-Chorrillo-Panama-City-Hotels.0-n553248623199107689-0.Travel-Guide-Filter-Hotels) - [Hotels near Estación Lotería](https://www.expedia.co.uk/Estacion-Loteria-Hotels.d553248635125946139.Travel-Guide-Hotels) - [Hotels near Fuerte Amador Resort & Marina](https://www.expedia.co.uk/Fuerte-Amador-Resort-Marina-Hotels.0-l553248621532964846-0.Travel-Guide-Filter-Hotels) - [Hotels near Isla Flamenco Shopping Center](https://www.expedia.co.uk/Isla-Flamenco-Shopping-Center-Hotels.0-l553248621532963847-0.Travel-Guide-Filter-Hotels) - [Marbella Hotels](https://www.expedia.co.uk/Marbella-Panama-City-Hotels.0-n3000663483-0.Travel-Guide-Filter-Hotels) - [Hotels near Marcos A. Gelabert Intl.](https://www.expedia.co.uk/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels) - [Hotels near Multicentro Panama](https://www.expedia.co.uk/Multicentro-Panama-Hotels.0-l6158230-0.Travel-Guide-Filter-Hotels) - [Obarrio Hotels](https://www.expedia.co.uk/Obarrio-Panama-City-Hotels.0-n3000663487-0.Travel-Guide-Filter-Hotels) - [Panama City Hotels](https://www.expedia.co.uk/Panama-City-Hotels.d2897.Travel-Guide-Hotels) - [Parque Lefevre Hotels](https://www.expedia.co.uk/Parque-Lefevre-Panama-City-Hotels.0-n553248623199116155-0.Travel-Guide-Filter-Hotels) - [Punta Pacifica Hotels](https://www.expedia.co.uk/Punta-Pacifica-Panama-City-Hotels.0-n3000663482-0.Travel-Guide-Filter-Hotels) - [Punta Paitilla Hotels](https://www.expedia.co.uk/Punta-Paitilla-Panama-City-Hotels.0-n6285983-0.Travel-Guide-Filter-Hotels) - [San Felipe Hotels](https://www.expedia.co.uk/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels) - [San Francisco Hotels](https://www.expedia.co.uk/San-Francisco-Panama-City-Hotels.0-n553248623199112076-0.Travel-Guide-Filter-Hotels) - [Hotels near Vía Argentina](https://www.expedia.co.uk/Via-Argentina-Hotels.d553248635998074175.Travel-Guide-Hotels) - [Flights to Marcos A. Gelabert Intl.](https://www.expedia.co.uk/Cheap-Flights-To-Marcos-A-Gelabert-Intl.d4407632.Travel-Guide-Flights) - [Flights from Marcos A. Gelabert Intl.](https://www.expedia.co.uk/lp/airports/pac/flights-from-marcos-a-gelabert-intl-airport) - [Hahn Air Technologies Bocas del Toro (BOC) to Panama City (PAC) flights](https://www.expedia.co.uk/lp/flight-routes/hahn-air-technologies-from-bocas-del-toro-intl-to-marcos-a-gelabert-intl/x1/boc/pac) - [Flights from Bilbao (BIO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bio/pac/bilbao-to-panama-city) - [Flights from Bocas del Toro (BOC) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/boc/pac/bocas-del-toro-to-panama-city) - [Flights from Baltimore (BWI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bwi/pac/baltimore-to-panama-city) - [Flights from Belize City (BZE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/bze/pac/belize-city-to-panama-city) - [Flights from Columbia (CAE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cae/pac/columbia-to-panama-city) - [Flights from Waco Kungo (CEO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ceo/pac/waco-kungo-to-panama-city) - [Flights from Changuinola (CHX) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/chx/pac/changuinola-to-panama-city) - [Flights from Chi Mei (CMJ) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/cmj/pac/chi-mei-to-panama-city) - [Flights from Cartagena (CTG) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ctg/pac/cartagena-to-panama-city) - [Flights from David (DAV) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/dav/pac/david-to-panama-city) - [Flights from Delhi (DEL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/del/pac/delhi-to-panama-city) - [Flights from Durban (DUR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/dur/pac/durban-to-panama-city) - [Flights from Dubai (DXB) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/dxb/pac/dubai-to-panama-city) - [Flights from La Fortuna (FON) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/fon/pac/la-fortuna-to-panama-city) - [Flights from Frankfurt (FRA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/fra/pac/frankfurt-to-panama-city) - [Flights from Ghimbi (GHD) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ghd/pac/ghimbi-to-panama-city) - [Flights from Glasgow (GLA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gla/pac/glasgow-to-panama-city) - [Flights from Guatemala City (GUA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gua/pac/guatemala-city-to-panama-city) - [Flights from Guayaquil (GYE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/gye/pac/guayaquil-to-panama-city) - [Flights from Hong Kong (HKG) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/hkg/pac/hong-kong-to-panama-city) - [Flights from Houston (HOU) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/hou/pac/houston-to-panama-city) - [Flights from Chigorodo (IGO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/igo/pac/chigorodo-to-panama-city) - [Flights from Istanbul (IST) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ist/pac/istanbul-to-panama-city) - [Flights from Jabalpur (JLR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/jlr/pac/jabalpur-to-panama-city) - [Flights from La Paz (LAP) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lap/pac/la-paz-to-panama-city) - [Flights from Las Vegas (LAS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/las/pac/las-vegas-to-panama-city) - [Flights from Los Angeles (LAX) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lax/pac/los-angeles-to-panama-city) - [Flights from London (LHR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lhr/pac/london-to-panama-city) - [Flights from Liberia (LIR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lir/pac/liberia-to-panama-city) - [Flights from London (LON) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/lon/pac/london-to-panama-city) - [Flights from Medellín (MDE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mde/pac/medellin-to-panama-city) - [Flights from Mamfe (MMF) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/mmf/pac/mamfe-to-panama-city) - [Flights from Nice (NCE) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/nce/pac/nice-to-panama-city) - [Flights from Newcastle (NCL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ncl/pac/newcastle-to-panama-city) - [Flights from Para Chinar (PAJ) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/paj/pac/para-chinar-to-panama-city) - [Flights from Pointe-a-Pitre (PTP) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/ptp/pac/pointe-a-pitre-to-panama-city) - [Flights from Panama City (PTY) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/pty/pac/panama-city-to-panama-city) - [Flights from San Salvador (SAL) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sal/pac/san-salvador-to-panama-city) - [Flights from San Antonio (SAT) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sat/pac/san-antonio-to-panama-city) - [Flights from Santo Domingo (SDQ) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sdq/pac/santo-domingo-to-panama-city) - [Flights from San José (SJO) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sjo/pac/san-jose-to-panama-city) - [Flights from San Juan (SJU) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sju/pac/san-juan-to-panama-city) - [Flights from Springfield (SPI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/spi/pac/springfield-to-panama-city) - [Flights from Santiago (STI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/sti/pac/santiago-to-panama-city) - [Flights from Syracuse (SYR) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/syr/pac/syracuse-to-panama-city) - [Flights from Trinidad (TAD) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tad/pac/trinidad-to-panama-city) - [Flights from Tapachula (TAP) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tap/pac/tapachula-to-panama-city) - [Flights from Tampa (TPA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tpa/pac/tampa-to-panama-city) - [Flights from Tulcan (TUA) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/tua/pac/tulcan-to-panama-city) - [Flights from Uberlandia (UDI) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/udi/pac/uberlandia-to-panama-city) - [Flights from Fort Walton Beach (VPS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/vps/pac/fort-walton-beach-to-panama-city) - [Flights from Owen Sound (YOS) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/yos/pac/owen-sound-to-panama-city) - [Flights from Zürich (ZRH) to Panama City (PAC)](https://www.expedia.co.uk/lp/flights/zrh/pac/zurich-to-panama-city) - [Albrook Shopping Mall](https://www.expedia.co.uk/Albrook-Shopping-Mall-Panama-City.d6159851.Attraction) - [Calidonia Holidays](https://www.expedia.co.uk/Calidonia.d3000663488.Holidays-City-Breaks) - [Cinta Costera](https://www.expedia.co.uk/Cinta-Costera-Calidonia.d6245970.Attraction) - [Metropolitan Cathedral of Panama](https://www.expedia.co.uk/Metropolitan-Cathedral-Of-Panama-Casco-Viejo.d6078477.Attraction) - [Palacio Bolivar](https://www.expedia.co.uk/Palacio-Bolivar-Casco-Viejo.d553248621562725897.Attraction) - [Visit Calidonia](https://www.expedia.co.uk/Panama-City-Calidonia.dx3000663488) - [Visit Curundu](https://www.expedia.co.uk/Panama-City-Curundu.dx553248623199107736) - [Visit El Chorrillo](https://www.expedia.co.uk/Panama-City-El-Chorrillo.dx553248623199107689) - Explore a world of travel with Expedia ### Hotels in top Panama City neighborhoods - [Hotels in Casco Viejo](https://expedia.co.uk/Casco-Viejo-Panama-City-Hotels.0-n6285189-0.Travel-Guide-Filter-Hotels) - [Hotels in Bella Vista](https://expedia.co.uk/Bella-Vista-Panama-City-Hotels.0-n3000663485-0.Travel-Guide-Filter-Hotels) - [Hotels in El Cangrejo](https://expedia.co.uk/El-Cangrejo-Panama-City-Hotels.0-n6285972-0.Travel-Guide-Filter-Hotels) - [Hotels in San Francisco](https://expedia.co.uk/San-Francisco-Panama-City-Hotels.0-n553248623199112076-0.Travel-Guide-Filter-Hotels) - [Hotels in Punta Paitilla](https://expedia.co.uk/Punta-Paitilla-Panama-City-Hotels.0-n6285983-0.Travel-Guide-Filter-Hotels) - [Hotels in Calidonia](https://expedia.co.uk/Calidonia-Panama-City-Hotels.0-n3000663488-0.Travel-Guide-Filter-Hotels) - [Hotels in San Felipe](https://expedia.co.uk/San-Felipe-Panama-City-Hotels.0-n829297728598073344-0.Travel-Guide-Filter-Hotels) - [Hotels in Costa del Este](https://expedia.co.uk/Costa-Del-Este-Panama-City-Hotels.0-n3000663480-0.Travel-Guide-Filter-Hotels) - [Hotels in Marbella](https://expedia.co.uk/Marbella-Panama-City-Hotels.0-n3000663483-0.Travel-Guide-Filter-Hotels) - [Hotels in Punta Pacifica](https://expedia.co.uk/Punta-Pacifica-Panama-City-Hotels.0-n3000663482-0.Travel-Guide-Filter-Hotels) - [Hotels in Amador](https://expedia.co.uk/Amador-Panama-City-Hotels.0-n553248635933392377-0.Travel-Guide-Filter-Hotels) - [Hotels in Campo Alegre](https://expedia.co.uk/Campo-Alegre-Panama-City-Hotels.0-n553248635976397615-0.Travel-Guide-Filter-Hotels) - [Hotels in Obarrio](https://expedia.co.uk/Obarrio-Panama-City-Hotels.0-n3000663487-0.Travel-Guide-Filter-Hotels) - [Hotels in Santa Ana](https://expedia.co.uk/Santa-Ana-Panama-City-Hotels.0-n553248623199107606-0.Travel-Guide-Filter-Hotels) - [Hotels in Balboa](https://expedia.co.uk/Balboa-Panama-City-Hotels.0-n6323179-0.Travel-Guide-Filter-Hotels) - [Hotels in El Chorrillo](https://expedia.co.uk/El-Chorrillo-Panama-City-Hotels.0-n553248623199107689-0.Travel-Guide-Filter-Hotels) - [Hotels in Juan Diaz](https://expedia.co.uk/Juan-Diaz-Panama-City-Hotels.0-n553248623199113945-0.Travel-Guide-Filter-Hotels) - [Hotels in Parque Lefevre](https://expedia.co.uk/Parque-Lefevre-Panama-City-Hotels.0-n553248623199116155-0.Travel-Guide-Filter-Hotels) - [Hotels in Curundu](https://expedia.co.uk/Curundu-Panama-City-Hotels.0-n553248623199107736-0.Travel-Guide-Filter-Hotels) - [Hotels in Don Bosco](https://expedia.co.uk/Don-Bosco-Panama-City-Hotels.0-n829297665731731456-0.Travel-Guide-Filter-Hotels) ### Hotels near popular Panama City Attractions - [Hotels near Albrook Shopping Mall](https://expedia.co.uk/Albrook-Shopping-Mall-Hotels.0-l6159851-0.Travel-Guide-Filter-Hotels) - [Hotels near Cinta Costera](https://expedia.co.uk/Cinta-Costera-Hotels.0-l6245970-0.Travel-Guide-Filter-Hotels) - [Hotels near Amador Causeway](https://expedia.co.uk/Amador-Causeway-Hotels.0-l6286127-0.Travel-Guide-Filter-Hotels) - [Hotels near Fuerte Amador Resort & Marina](https://expedia.co.uk/Fuerte-Amador-Resort-Marina-Hotels.0-l553248621532964846-0.Travel-Guide-Filter-Hotels) - [Hotels near Gamboa Rainforest Resort](https://expedia.co.uk/Gamboa-Rainforest-Resort-Hotels.0-l6078513-0.Travel-Guide-Filter-Hotels) ### More accommodation types in Santa Ana - [Serviced Apartments in Panama City](https://expedia.co.uk/Panama-City-Apart-Hotels.d2897-aaApartHotels.Travel-Guide-Accommodation) - [Hostels in Panama City](https://expedia.co.uk/Panama-City-Hostels.d2897-aaHostels.Travel-Guide-Accommodation) - [Lodges in Panama City](https://expedia.co.uk/Panama-City-Lodges.d2897-aaLodges.Travel-Guide-Accommodation) ### Hotels Close to Nearby Airports - [Hotels near Tocumen Intl. Airport](https://expedia.co.uk/Tocumen-Intl-Airport-Hotels.0-aPTY-0.Travel-Guide-Filter-Hotels) - [Hotels near Marcos A. Gelabert Intl. Airport](https://expedia.co.uk/Marcos-A-Gelabert-Intl-Airport-Hotels.0-aPAC-0.Travel-Guide-Filter-Hotels) - [Hotels near Panama Pacifico Intl. Airport](https://expedia.co.uk/Panama-Pacifico-Intl-Airport-Hotels.0-aBLB-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Studio Coliving](https://expedia.co.uk/Panama-City-Hotels-Studio-Coliving.h75284683.Hotel-Information) - [Central Hotel Panama Casco Viejo](https://expedia.co.uk/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) - [JW Marriott Panama](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) - [Decapolis Hotel Panama City](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) - [Waldorf Astoria Panama](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) - [Marriott Panama Hotel](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) - [Novotel Panama City](https://expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) - [Las Americas Golden Tower Panama](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) - 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