A gazebo with columns, a large tree with hanging roots, and a building in the background.

Search Hotels in Santa Ana, Panama City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Santa Ana hotels

1. Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (105 reviews)
"Always an amazing stay"
United States
chris
The price is £76
includes taxes & fees
31 Aug - 1 Sept
Casco View Apartments

2. Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo
3.0 star property
Santa Ana
8.0 out of 10, Very good, (5 reviews)
"It is what you would expect for the $30/ night. Clean bed, and room, a/c worked well, limited water for showers at times, limited hot water. Great location for walking around close to Casco Viejo."
United States
William
The price is £30
includes taxes & fees
13 Sept - 14 Sept
Hotel Caracas - Casco Viejo

3. Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (73 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is £23
includes taxes & fees
27 Aug - 28 Aug
Hostal La Cigarra

4. ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.2 out of 10, (12 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is £19
includes taxes & fees
26 Sept - 27 Sept
ART CASCO The Hotel

5. Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (196 reviews)
"Good location. Walking distance to shops and public transport."
Canada
Danilo
The price is £66
includes taxes & fees
26 Sept - 27 Sept
Hotel República

6. Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is £20
includes taxes & fees
28 Aug - 29 Aug
Hotel Riazor

7. La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (18 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is £75
includes taxes & fees
27 Aug - 28 Aug
La Manzana Barrio Vivo by Wynwood

8. Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
Santa Ana
2.0 out of 10, (1 review)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is £93
includes taxes & fees
27 Aug - 28 Aug
Room-sofa Bed Stay Rooftop Pool & Gym, A

9. Hotel Casa Panamá

Hotel Casa Panamá
4.0 star property
San Felipe, 0.4 mi from Santa Ana
7.6 out of 10, Good, (745 reviews)
"Beautifully decorated. Great location! Staff very helpful."
United States
Mariana
The price is £49
includes taxes & fees
24 Sept - 25 Sept
Hotel Casa Panamá

10. Hotel Magnolia Boutique

Hotel Magnolia Boutique
2.0 star property
San Felipe, 0.4 mi from Santa Ana
8.8 out of 10, Excellent, (506 reviews)
"Super nice hotel, very clean and location is amazing"
United States
Boris
The price is £64
includes taxes & fees
27 Aug - 28 Aug
Hotel Magnolia Boutique

11. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.5 mi from Santa Ana
9.2 out of 10, Wonderful, (1,003 reviews)
"Love the breakfast and the rooms were amazing"
United States
querube
The price is £164
includes taxes & fees
25 Sept - 26 Sept
Central Hotel Panama Casco Viejo

12. Oasis Hotel

Oasis Hotel
3.0 star property
San Felipe, 0.4 mi from Santa Ana
8.6 out of 10, Excellent, (150 reviews)
"Great stay! Highly recommend"
United States
Gregg
The price is £47
includes taxes & fees
21 Sept - 22 Sept
Oasis Hotel

13. Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 0.4 mi from Santa Ana
8.8 out of 10, Excellent, (327 reviews)
"Great Location , helpful staff"
United States
David
The price is £73
includes taxes & fees
20 Sept - 21 Sept
Tantalo Hotel

14. American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.4 mi from Santa Ana
9.4 out of 10, Exceptional, (802 reviews)
"A lovely friendly hotel with excellent staff"
United Kingdom
Ann
The price is £198
includes taxes & fees
1 Sept - 2 Sept
American Trade Hotel

15. Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 0.4 mi from Santa Ana
9.4 out of 10, Exceptional, (444 reviews)
"Everything was excellent"
United States
ORLANDO RICARDO
The price is £117
includes taxes & fees
5 Sept - 6 Sept
Hotel San Felipe

16. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
San Felipe, 0.5 mi from Santa Ana
9.8 out of 10, Exceptional, (347 reviews)
"One of our favorite stays. Right in old town, walking distance to everything. Beautiful room, beautifal courtyard. Their on-site restaurants were also excellent."
United States
Reid
The price is £261
includes taxes & fees
17 Sept - 18 Sept
Hotel La Compañía Casco Antiguo

17. La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
San Felipe, 0.3 mi from Santa Ana
9.6 out of 10, Exceptional, (235 reviews)
"Very nice rooms and bathrooms. Great location in Casco Viejo"
Canada
Shrinand
The price is £162
includes taxes & fees
1 Sept - 2 Sept
La Concordia Boutique Hotel

18. Hotel Caribe

Hotel Caribe
3.0 star property
Calidonia, 0.7 mi from Santa Ana
7.6 out of 10, Good, (330 reviews)
"Hotel clean and staff is great the facilities need a little updating there is no good bilingual help closed to everything my stay was great"
United States
dave
The price is £34
includes taxes & fees
30 Aug - 31 Aug
Hotel Caribe

19. Canova

Canova
3.0 star property
Calidonia, 0.9 mi from Santa Ana
8.0 out of 10, Very good, (199 reviews)
"I loved the location as it was within walking distance to the metro and on two stops to get to albrook also titan was just around the corner and el costo and a lot of other store where within walking distance to the hotel"
United States
Gizelle
The price is £24
includes taxes & fees
27 Aug - 28 Aug
Canova

20. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 0.7 mi from Santa Ana
9.8 out of 10, Exceptional, (730 reviews)
"It was an amazing stay! The only place we would stay in Panama City."
United States
Josh
The price is £280
includes taxes & fees
20 Sept - 21 Sept
Sofitel Legend Casco Viejo, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.
Casco View Apartments
3.5 star property
9.0
Wonderful
105 reviews
View
Hotel Caracas - Casco Viejo
3.0 star property
8.0
Very good
5 reviews
View
A restaurant with a long counter, chairs, and tables. There are plants and lights decorating the space.
Hostal La Cigarra
2.0 star property
7.6
Good
73 reviews
View
A hotel entrance with a green facade and a metal fence.
ART CASCO The Hotel
2.0 star property
6.2
12 reviews
View
A hotel room with a large bed, a window with curtains, a city view, and a lamp.
Hotel República
2.0 star property
6.8
196 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most. Learn more about Santa Ana
Learn more about Santa Ana

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Cultural Explorations: Engage in walking tours to uncover Santa Ana's rich heritage, including the Santa Ana Church and local museums.
  • Vibrant Atmosphere: Experience the lively community, enhanced by friendly locals and a bustling city vibe.
  • Shopping Delights: Enjoy vibrant shopping areas that offer a variety of local goods and unique finds.
  • Family-Friendly Activities: Discover attractions suitable for families, ensuring a fun experience for all ages.
  • Diverse Accommodation: Choose from a range of delightful hotels and rentals, catering to every traveller's needs.

Find great hotels near Santa Ana

Discover a range of delightful accommodation options in Santa Ana, Panama City, designed to cater to all types of travellers. From pet-friendly hotels to charming apartments, you'll find the perfect base for your Panamanian adventure. Whether you're seeking a city-themed escape or a business-friendly environment, Santa Ana offers a variety of vacation rentals and hotels to ensure a memorable stay.

  • Central Hotel Panama Casco Viejo: Central Hotel Panama Casco Viejo is a charming 4-star hotel with a guest rating of 9.0, ideal for those seeking a romantic and city-themed getaway. Located 805m from Santa Ana, this hotel offers a blend of modern amenities and romantic experiences, including special packages for couples. Guests can indulge in a range of food and beverage services, such as Champagne Service and 24-hour Room Service, perfect for an intimate evening. The hotel also features a spa, steam room, and pool area, allowing travellers to unwind and rejuvenate together in a serene atmosphere.
  • American Trade Hotel: With a 4.5-star rating and a guest rating of 9.4, the American Trade Hotel is a family-friendly destination located 644m from Santa Ana. This hotel is perfect for adventurers, offering various activities like Segway and bicycle rentals, hiking, and more nearby. Families can take advantage of amenities tailored for children, including cribs and breakfast options. The hotel also provides romance packages, and guests can enjoy scenic views from the restaurant, alongside limited-hours room service and a lovely outdoor pool area for relaxation and enjoyment.
  • Sofitel Legend Casco Viejo, Panama City: Sofitel Legend Casco Viejo, Panama City is a luxurious 5-star hotel boasting an impressive guest rating of 9.8, situated 1.1km from Santa Ana. This upscale property is designed for discerning travellers seeking a lavish experience, offering a full spa and pool service, including massage treatments and aromatherapy. Guests will appreciate the elegant decor and top-notch facilities, including a Poolside Bar for refreshing drinks, creating an oasis of relaxation in the heart of the city.

Where to stay near Santa Ana

Santa Ana, a vibrant neighbourhood in Panama City, offers a delightful mix of family-friendly attractions and bustling business vibes. Visitors can immerse themselves in the lively atmosphere, where friendly locals enhance the Panamanian experience. Just a stone's throw away, explore nearby regions that showcase the best of Panamá Province, from relaxing parks to luxury dining. Whether you're seeking adventure or relaxation, Santa Ana is the perfect gateway to discover the charm of Panama.

  • Panama City: As the bustling capital of Panama, Panama City offers a vibrant mix of modern skyscrapers and historical landmarks. Situated around Santa Ana, it serves as a gateway to a wealth of experiences. The city sees a steady influx of visitors year-round, particularly peaking in January, July, and September. Tourists flock to Panama City for family outings, corporate events, and urban exploration. You can indulge in shopping at various centres and enjoy the local beaches and parks that add to the city's charm. Don't miss the chance to wander its lively streets, teeming with culture and local flair.
  • Casco Viejo: Just 644m from Santa Ana, Casco Viejo is a historic neighbourhood that enchants visitors with its colonial architecture and vibrant atmosphere. Popular year-round, especially in January and during the March to April period, this area attracts families, business travellers, and culture enthusiasts alike. The cobblestone streets are lined with boutique shops, chic resorts, and delightful cafes. With its proximity to parks and the beach, Casco Viejo offers a perfect blend of leisure and exploration. Make sure to visit its iconic plazas and experience the rich history that permeates every corner.
  • San Felipe: Similarly located only 644m from Santa Ana, San Felipe is known for its striking historical significance and vibrant community. This neighbourhood experiences a steady flow of tourists, particularly from December to February. It caters to families and business-focused travellers, providing access to shopping areas and resorts. With scenic parks and beautiful streets nearby, San Felipe offers a unique charm that complements its lively atmosphere. Strolling through its streets, you'll find local vendors and cultural gems that reflect the essence of Panama.

Things to do in Santa Ana

Santa Ana in Panama City offers a delightful blend of activities suitable for families and business travellers alike. Visitors can enjoy walking tours to explore the local culture, visit the vibrant shopping areas, or relax at nearby resorts. Highlights include guided tours of Santa Ana and Panama City, making it easy to immerse yourself in the region's rich heritage and bustling atmosphere.

Shopping

Discover Santa Ana's vibrant shopping scene at Albrook Mall, one of the largest in Central America, featuring a wide array of shops, restaurants, and entertainment options. For a more local experience, visit the Mercado de Santa Ana, where you can find unique souvenirs and traditional crafts.

Recreation

Experience tranquility at the Santa Ana Wellness Centre, where you can indulge in rejuvenating spa treatments and yoga sessions. Explore nearby Parque Natural Metropolitano for nature walks and birdwatching, offering a perfect blend of relaxation and outdoor adventure in a serene environment.

Adventure

Explore the vibrant Santa Ana neighbourhood, where colourful street art adorns the walls and local markets offer a taste of Panamanian culture. Venture to the nearby Ancon Hill for stunning panoramic views and exhilarating hiking trails amidst lush tropical flora and fauna.

Nightlife

In Santa Ana, Panama City, the vibrant nightlife pulsates with energy. Venues like Casco Viejo and La Tana offer lively bars and dance spots, while El Cangrejo is famous for its bustling atmosphere and diverse entertainment options. Enjoy local rhythms and flavours in this captivating district.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Ana

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Santa Ana are September to November, where the prices are slightly lower. This is in comparison to March and December to January, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Santa Ana is Tuesday. The most expensive day to stay around Santa Ana is Saturday.
  • Find cheap hotels on Expedia: Utilise Expedia’s search tool to refine your preferences, including your budget, desired location, and preferred type of accommodation. To uncover the most affordable prices and offers, arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can enjoy savings by combining your hotel stay in Santa Ana with your flights and activities through an Expedia package deal.

Find the best attractions near Santa Ana

Santa Ana in Panama City is perfect for family, business, and city-themed holidays. Visitors can explore a variety of attractions, including the Santa Ana Church and San Miguel, as well as enjoy the scenic hills and local history at nearby museums. With a blend of culture and outdoor experiences, Santa Ana offers something for everyone, making it an ideal destination for those seeking to immerse themselves in the rich heritage of Panama.

  • Ancon Hill: Situated 966m from Santa Ana, Ancon Hill offers breathtaking panoramic views of Panama City and the surrounding rainforest. This serene outdoor space is perfect for hiking enthusiasts and nature lovers, providing a tranquil escape from the bustling city.
  • Metropolitan Cathedral of Panama: Located 805m from Santa Ana, this impressive cathedral showcases a stunning blend of architectural styles, reflecting Panama's rich cultural heritage. Visitors can admire its intricate designs and participate in local religious practices.
  • Interoceanic Canal Museum: Just 805m from Santa Ana, this museum delves into the fascinating history of the Panama Canal. Exhibits highlight the canal's construction and its significance, making it an essential stop for culture enthusiasts.

Best time to go to Santa Ana

The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnySlightly HighSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnyAverageSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageAverage
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighSlightly High

The nearest major airports for your trip to Santa Ana

Visiting Santa Ana is convenient with three major airports nearby. Panama City (PTY-Tocumen Intl.) is located 20.9km away, with luxurious hotels such as The Santa Maria, JW Marriott Panama, and Hilton Panama offering various transport services including airport shuttles. The closer Panama City (PAC-Marcos A. Gelabert Intl.) is only 3.2km away, featuring hotels like W Panama and Sofitel Legend Casco Viejo, providing 24-hour shuttle services. Balboa (BLB-Panama Pacifico Intl.) is just 6.4km from Santa Ana, with options like Waldorf Astoria Panama and Bristol Panama, both offering comprehensive transport solutions. Each airport ensures easy access to the vibrant city and its attractions.

Frequently asked questions

What are the best hotels in Santa Ana that travellers recommend?
For a popular hotel in Santa Ana, consider Hostal La Cigarra.

Hostal La Cigarra, with a rating of 7.6, is particularly noted by guests for its convenient location and comfortable rooms. This property features a traditional design and is situated within a historical district, close to a shopping district. It is also very convenient for visiting local attractions, being only 0.6 km from the Museum of History Panama and the Mola Museum. Other nearby points of interest include Cinta Costera, 1.6 km away, and Avenida Balboa, 3.6 km away.
What are the top pet-friendly hotels in Santa Ana?
For a top pet-friendly hotel in Santa Ana, you should consider Hostal La Cigarra.

Hostal La Cigarra, with a 7.6 rating, is a pet-friendly accommodation that permits pets and charges a cleaning amount for them. It is located in a historical district, making it convenient for exploring sites like the Museum of History Panama and the Mola Museum, both just 0.6 km away. Guests have frequently commented on its convenient location and comfortable rooms.
What are the best budget hotels in Santa Ana?
For budget-friendly accommodation in Santa Ana, you might consider Hostal La Cigarra, Hotel República, or ART CASCO The Hotel.

Hostal La Cigarra, with a rating of 7.6, provides free WiFi and is located in a historical district, close to the Amador Theater and the Museum of History Panama. Guests often comment on its convenient location and comfortable rooms.

Hotel República offers free WiFi and a lovely terrace, including a rooftop terrace, for guests to enjoy. It is also situated within a historical district.

ART CASCO The Hotelprovides free WiFi and is conveniently located near museums and a historical district. It also offers nearby offsite parking with a discount.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Ana.
How much is the nightly rate at a Santa Ana hotel?
Hotel prices in Santa Ana often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia