Title: TOP Business Hotels in Ortygia for 2025 | Expedia.co.uk [Ortygia Travel Guide](https://expedia.co.uk/Ortygia.dx6182482)[Hotels in Ortygia](https://expedia.co.uk/Ortygia-Hotels.d6182482.Travel-Guide-Hotels)[Holiday Rentals in Ortygia](https://expedia.co.uk/Ortygia-Holiday-Rentals.d6182482.Travel-Guide-HolidayRentals)[Flights to Ortygia](https://expedia.co.uk/Cheap-Flights-To-Ortygia.d6182482.Travel-Guide-Flights)[Things to do in Ortygia](https://expedia.co.uk/Things-To-Do-In-Ortygia.d6182482.Travel-Guide-Activities)[Ortygia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Ortygia.d6182482.Car-Hire-Guide)[Ortygia Holidays](https://expedia.co.uk/Ortygia.d6182482.Holidays-City-Breaks) ![Ortygia featuring street scenes and markets as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87652-Ortygia.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Ortygia ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Ortygia Business Hotels Tonight [20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2025-09-20&endDate=2025-09-21&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [21 Sept - 22 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2025-09-21&endDate=2025-09-22&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2025-09-26&endDate=2025-09-28&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Ortygia Business Hotels ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1760000/1759000/1758948/02859755.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1760000/1759000/1758948/57f02aa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Buffet](https://images.trvl-media.com/lodging/2000000/1760000/1759000/1758948/b2229263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1760000/1759000/1758948/b4fdcb22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alla Giudecca Ortigia 8.4/10 Very good (267) "The property is well located. However, the amenities are limited. Isabella, one of the employees, was very friendly and helpful. The rest of the staff, in my experience, were rude." [](https://www.expedia.co.uk/Syracuse-Hotels-Alla-Giudecca.h1758948.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/980000/974100/974007/5db9500b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/980000/974100/974007/f6f308be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/980000/974100/974007/e466bf8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner served; Italian cuisine, al fresco dining ](https://images.trvl-media.com/lodging/1000000/980000/974100/974007/3a48ad54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Artemide - VRetreats Ortigia 9.4/10 Exceptional (652) "Great hotel" £381 includes taxes & fees 3 Oct - 4 Oct [](https://www.expedia.co.uk/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information) ![Building design](https://images.trvl-media.com/lodging/1000000/980000/976400/976389/c9e03ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/980000/976400/976389/2e723fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/980000/976400/976389/cbf3a060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/980000/976400/976389/30aef09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Des Ètrangers - The Leading Hotels of the World Ortigia 9.6/10 Exceptional (68) "Location, staff were amazing" £565 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Des-Etrangers.h976389.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fcb5d184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fe8a6bf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/7f10ab55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/284340c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Domus Mariae Albergo Ortigia 9.2/10 Wonderful (312) "Great hospitality. Very clean and staff very helpful. Enjoyed our stay very much. " £156 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/3000000/2540000/2539800/2539747/452ccadd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2540000/2539800/2539747/d8e33263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2540000/2539800/2539747/2a5f3b77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2540000/2539800/2539747/dc5484a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Domus Mariae Benessere Ortigia 9.0/10 Wonderful (225) "The staff was very nice." £206 includes taxes & fees 27 Sept - 28 Sept [](https://www.expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Benessere.h2539747.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/206c3f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch served; international cuisine, al fresco dining ](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/cc080552.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food court](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/345642c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/68366634.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Ortigia Siracusa Ortigia 9.0/10 Wonderful (555) "Great stay!" £257 includes taxes & fees 7 Oct - 8 Oct [](https://www.expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/b9e3b8e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/27da8058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/2f13634a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/f325b30d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Gutkowski Ortigia 8.8/10 Excellent (126) "Excellent front desk staff. Very tasteful decorations. Get the balcony. Great breeze off the ocean. Loved the spacious room. Close to parking garage was great. " [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Gutkowski.h2535838.Hotel-Information) ![Spa](https://images.trvl-media.com/lodging/4000000/3050000/3045700/3045685/429c77fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![30-inch TV with digital channels](https://images.trvl-media.com/lodging/4000000/3050000/3045700/3045685/997b5fe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/4000000/3050000/3045700/3045685/cbbd6afe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3050000/3045700/3045685/5246221b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Livingston Siracusa Ortigia 9.0/10 Wonderful (257) "Beautiful view of the ocean. But the room was very small." [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Livingston-Siracusa.h3045685.Hotel-Information) ![Free daily cooked-to-order breakfast ](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/235f3413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/6baaad51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/100407e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/cb884c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posta Ortigia 8.4/10 Very good (437) "Small affordable hotel with a small sea view. Only one small garage parking space. " £111 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Posta.h917761.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/3b8d7262.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine ](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/d211e44f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/7ca88e14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Sea View | 1 bedroom, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/w3995h2667x0y0-8f06942a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ortea Palace Hotel, Sicily, Autograph Collection Ortigia 9.4/10 Exceptional (240) "Great location and very friendly staff" £426 includes taxes & fees 10 Oct - 11 Oct [](https://www.expedia.co.uk/Syracuse-Hotels-Ortea-Palace-Luxury-Hotel.h17825841.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-04&endDate=2025-10-05®ionId=6182482&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Ortygia Hotel Reviews ![Grand Hotel Des Ètrangers - The Leading Hotels of the World](//images.trvl-media.com/lodging/1000000/980000/976400/976389/c9e03ff2_y.jpg) ### Grand Hotel Des Ètrangers - The Leading Hotels of the World 10/10 Excellent "Great hotel in a fantastic location. Staff very helpful.Beautiful pool with great views. " [](https://expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Des-Etrangers.h976389.Hotel-Information) ![Ortea Palace Hotel, Sicily, Autograph Collection](//images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/3b8d7262_y.jpg) ### Ortea Palace Hotel, Sicily, Autograph Collection 10/10 Excellent "We thoroughly enjoyed our stay. The staff went above and beyond - wonderful people who truly cared about the guest experience. Historic building and truly lovely to explore. " [](https://expedia.co.uk/Syracuse-Hotels-Ortea-Palace-Luxury-Hotel.h17825841.Hotel-Information) ![Charme Hotel Henry's House](//images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/f02c4712_y.jpg) ### Charme Hotel Henry's House 10/10 Excellent "Wonderful service and beautiful location. Would come back again to this dreamy place " [](https://expedia.co.uk/Syracuse-Hotels-Charme-Hotel-Henrys-House.h7797247.Hotel-Information) ![Algila' Ortigia Charme Hotel](//images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d402c8e9_y.jpg) ### Algila' Ortigia Charme Hotel 10/10 Excellent "Highly recommended! Helpful friendly staff and a beautiful hotel building. The breakfast was excellent too. This would be my top choice hotel for a stay in ortigia" [](https://expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![Domus Mariae Albergo](//images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fcb5d184_y.jpg) ### Domus Mariae Albergo 10/10 Excellent "Great hotel, perfect location. Swimming spot right outside in ocean with safety rocks to keep large sea life out. Lovely views. Friendly staff, comfortable beds and nice price. Don't miss this gem. " [](https://expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) ![Hotel Posta](//images.trvl-media.com/lodging/1000000/920000/917800/917761/235f3413_y.jpg) ### Hotel Posta 10/10 Excellent "This hotel is in a PERFECT location for exploring Ortigia and Siracusa, easy access to plenty of affordable parking, the staff is super friendly and welcoming (Grazie William for becoming our son’s new favorite person!), the room was clean and spacious enough for the 4 of us, and the rooftop happy hour and breakfast were UNFORGETTABLE! Wish we would’ve stayed here for more of our Sicily trip!" [](https://expedia.co.uk/Syracuse-Hotels-Hotel-Posta.h917761.Hotel-Information) ![Palazzo Artemide - VRetreats](//images.trvl-media.com/lodging/1000000/980000/974100/974007/5db9500b_y.jpg) ### Palazzo Artemide - VRetreats 10/10 Excellent "Very comfortable and very helpful." [](https://expedia.co.uk/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information) ![Domus Mariae Benessere](//images.trvl-media.com/lodging/3000000/2540000/2539800/2539747/452ccadd_y.jpg) ### Domus Mariae Benessere 10/10 Excellent "My husband & I stayed 2 nights in mid-May 2025. We loved this historic and fascinating B&B within a current convent (yes, we saw the nuns!). Comfortable 2nd floor room that opened onto a quiet, shared, shaded terrace. There’s also a ln upper terrace with seattle & sea views. The staff were very friendly and helpful. Note: wifi was very unreliable. We parked our rental car at the Talete garage about 10 minutes walk, for €15 per 24 hrs. Overall, this was a great location for us in Ortigia." [](https://expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Benessere.h2539747.Hotel-Information) ![Grand Hotel Ortigia Siracusa](//images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/206c3f7f_y.jpg) ### Grand Hotel Ortigia Siracusa 10/10 Excellent "Beautiful hotel right on the waterfront with parking (paid) just in front. Excellent service and breakfasts. Room elegant with high ceilings but would benefit from air conditioning for the summer months. Easy walking to seafront and around Ortigia. 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