Title: TOP Business Hotels in Ortygia for 2026 | Expedia.co.uk [Ortygia Travel Guide](https://expedia.co.uk/Ortygia.dx6182482)[Hotels in Ortygia](https://expedia.co.uk/Ortygia-Hotels.d6182482.Travel-Guide-Hotels)[Holiday Rentals in Ortygia](https://expedia.co.uk/Ortygia-Holiday-Rentals.d6182482.Travel-Guide-HolidayRentals)[Flights to Ortygia](https://expedia.co.uk/Cheap-Flights-To-Ortygia.d6182482.Travel-Guide-Flights)[Ortygia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Ortygia.d6182482.Car-Hire-Guide)[Ortygia Holidays](https://expedia.co.uk/Ortygia.d6182482.Holidays-City-Breaks) ![Ortygia featuring night scenes, a coastal town and heritage elements](https://images.trvl-media.com/place/6182482/72c39cd0-05b7-420f-b747-4c7f90143a9b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6182482/72c39cd0-05b7-420f-b747-4c7f90143a9b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Ortygia Business Hotels Tonight [10 Feb - 11 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2026-02-10&endDate=2026-02-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [11 Feb - 12 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Ortygia business-friendly hotels ![Front of property – evening/night](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/b9b70cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/cef34bb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/1067f2dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d4c370bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Algila' Ortigia Charme Hotel [](https://www.expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) Ortigia 9.6/10 Exceptional (922 reviews) "Nice room- great view. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) elizabeth £165 includes taxes & fees 12 Feb - 13 Feb [](https://www.expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![Daily buffet breakfast (EUR 8 per person)](https://images.trvl-media.com/lodging/19000000/18330000/18327700/18327666/fa1565cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18330000/18327700/18327666/24e33a10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Terrace | Terrace/patio](https://images.trvl-media.com/lodging/19000000/18330000/18327700/18327666/15744db5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite | Room amenity](https://images.trvl-media.com/lodging/19000000/18330000/18327700/18327666/9f4409d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dimore delle Zagare Ortigia [](https://www.expedia.co.uk/Syracuse-Hotels-Dimore-Delle-Zagare-Ortigia.h18327666.Hotel-Information) Ortigia 9.8/10 Exceptional (161 reviews) "Great location in the center of town. Staff was great and the rooms were very clean and comfortable. Would definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jayne £92 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Syracuse-Hotels-Dimore-Delle-Zagare-Ortigia.h18327666.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/3b8d7262.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine ](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/d211e44f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/d22de140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/3cd441f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ortea Palace Hotel, Sicily, Autograph Collection [](https://www.expedia.co.uk/Syracuse-Hotels-Ortea-Palace-Luxury-Hotel.h17825841.Hotel-Information) Ortigia 9.4/10 Exceptional (256 reviews) "The hotel itself is a beautiful building with an interesting heritage as the main post office. The location is excellent offering a great starting point for a walking tour of Ortigia. Great stay." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Craig £189 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Syracuse-Hotels-Ortea-Palace-Luxury-Hotel.h17825841.Hotel-Information) ![Balcony](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/121efcd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LCD TV](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fb513dce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fcb5d184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/20ffee31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Domus Mariae Albergo [](https://www.expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) Ortigia 9.2/10 Wonderful (346 reviews) "Lovely staff and unbeatable location! " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Grace Foggo £106 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/ac752df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach nearby, beach shuttle, sun-loungers, beach umbrellas](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/400d9c2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch served; international cuisine, al fresco dining ](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/cc080552.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/f86f7ffa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Ortigia Siracusa [](https://www.expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) Ortigia 9.0/10 Wonderful (576 reviews) "Every aspect of our stay was superb. The staff were friendly and helpfull. Our room was spotless, and the decor of the entire hotel was harmonious. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £163 includes taxes & fees 16 Feb - 17 Feb [](https://www.expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/de23622a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/cb884c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/6baaad51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Quadruple Room, Sea View | Hypo-allergenic bedding, down duvets, minibar, desk](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/0c4c08b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posta [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Posta.h917761.Hotel-Information) Ortigia 8.4/10 Very good (455 reviews) "The room was clean and the staff did a wonderful job preparing it each day while we were out and about. The staff was courteous and helpful, and I enjoyed the breakfast, too. I would definitely consider Hotel Posta again the next time I stay in Syracuse. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £71 includes taxes & fees 12 Feb - 13 Feb [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Posta.h917761.Hotel-Information) ![Deluxe Room | Hypo-allergenic bedding, down duvets, memory-foam beds, minibar](https://images.trvl-media.com/lodging/90000000/89730000/89720300/89720229/b6f5aa5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | Hypo-allergenic bedding, down duvets, memory-foam beds, minibar](https://images.trvl-media.com/lodging/90000000/89730000/89720300/89720229/da8fa3e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | Terrace/patio](https://images.trvl-media.com/lodging/90000000/89730000/89720300/89720229/11b63dd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/90000000/89730000/89720300/89720229/c56cd009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Joy's BnB Ortigia [](https://www.expedia.co.uk/Syracuse-Hotels-Xenia.h89720229.Hotel-Information) Ortigia 9.4/10 Exceptional (24 reviews) "Joy's BnB is very well located in one of the main streets of Ortigia, very clean room and the double windows isolate any street noise so you can rest very well, staff kind, and the breakfast included was good, not just coffee and bread." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raul [](https://www.expedia.co.uk/Syracuse-Hotels-Xenia.h89720229.Hotel-Information) ![Double Room, Sea View | View from room](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/8f7f490c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Sea View | Minibar, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/f3a78dc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/e7cd4c0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/2f13634a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Gutkowski [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Gutkowski.h2535838.Hotel-Information) Ortigia 8.8/10 Excellent (127 reviews) "Nice room with ocean view, helpful staff, the nearby market is very interesting " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sarah Shan £77 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Gutkowski.h2535838.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/34000000/33700000/33698500/33698430/3c868356.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, books, stereo](https://images.trvl-media.com/lodging/34000000/33700000/33698500/33698430/7110a9f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/34000000/33700000/33698500/33698430/d3c5f46f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/34000000/33700000/33698500/33698430/e4928326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cas'amuri is a detached house in the heart of Ortigia. [](https://www.expedia.co.uk/Syracuse-Hotels-House.h33698430.Hotel-Information) Ortigia 10/10 Exceptional (22 reviews) "Didn’t stay long enough to take full advantage of Stefania’s amazing apartment. Excellent location and super secret so quiet and relaxing. Great thoughtful amenities, she goes out of her way to make the place and your visit special. Would definitely stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michele S. £167 includes taxes & fees 5 Mar - 6 Mar [](https://www.expedia.co.uk/Syracuse-Hotels-House.h33698430.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8480000/8470400/8470355/98deac82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/9000000/8480000/8470400/8470355/49a91194.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food court](https://images.trvl-media.com/lodging/9000000/8480000/8470400/8470355/385dd357.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Delicatessen](https://images.trvl-media.com/lodging/9000000/8480000/8470400/8470355/d1966cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Parco delle Fontane [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Parco-Delle-Fontane.h8470355.Hotel-Information) Tiche 9.2/10 Wonderful (284 reviews) "Pool was excellent and the surrounding gardens superb " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ROBERT £70 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Parco-Delle-Fontane.h8470355.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25®ionId=6182482&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Ortygia Hotel Reviews ![Algila' Ortigia Charme Hotel](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d402c8e9_y.jpg) ### Algila' Ortigia Charme Hotel 10/10 Excellent "Nice stay. " [](https://expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![Hotel Posta](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/235f3413_y.jpg) ### Hotel Posta 10/10 Excellent "Variety of meats, cheeses, fresh fruits and veggies and breads/pastries-all delicious!" [](https://expedia.co.uk/Syracuse-Hotels-Hotel-Posta.h917761.Hotel-Information) ![Domus Mariae Albergo](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fcb5d184_y.jpg) ### Domus Mariae Albergo 10/10 Excellent "Beautiful Otigia! Most helpful staff!" [](https://expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) ![Ortea Palace Hotel, Sicily, Autograph Collection](https://images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/3b8d7262_y.jpg) ### Ortea Palace Hotel, Sicily, Autograph Collection 10/10 Excellent "Great hotel, great service. Well located, " [](https://expedia.co.uk/Syracuse-Hotels-Ortea-Palace-Luxury-Hotel.h17825841.Hotel-Information) ![Palazzo Artemide - VRetreats](https://images.trvl-media.com/lodging/1000000/980000/974100/974007/5db9500b_y.jpg) ### Palazzo Artemide - VRetreats 10/10 Excellent "Very clean, elegant and comfortable. Pleasant and helpful staff. " [](https://expedia.co.uk/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information) ![Grand Hotel Ortigia Siracusa](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/206c3f7f_y.jpg) ### Grand Hotel Ortigia Siracusa 10/10 Excellent "Stunning hotel and area on the waterfront in Ortigia. Strongly recommend everything except the restaurant. Food was marginal for the price with much better options close by" [](https://expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) ![Charme Hotel Henry's House](https://images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/f02c4712_y.jpg) ### Charme Hotel Henry's House 10/10 Excellent "Great location. Very friendly and helpful staff. Nice breakfast." [](https://expedia.co.uk/Syracuse-Hotels-Charme-Hotel-Henrys-House.h7797247.Hotel-Information) ![Grand Hotel Des Ètrangers - The Leading Hotels of the World](https://images.trvl-media.com/lodging/1000000/980000/976400/976389/c9e03ff2_y.jpg) ### Grand Hotel Des Ètrangers - The Leading Hotels of the World 10/10 Excellent "Great hotel and saff" [](https://expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Des-Etrangers.h976389.Hotel-Information) ![Alla Giudecca](https://images.trvl-media.com/lodging/2000000/1760000/1759000/1758948/02859755_y.jpg) ### Alla Giudecca 10/10 Excellent "We loved the history of the building, it was beautiful. Spacious rooms with outside sitting area. Walkable to all areas of interest in Ortigia and cafes and restaurants. Staff were helpful. 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