Title: TOP Business Hotels in Ortygia for 2025 | Expedia.co.uk [Ortygia Travel Guide](https://expedia.co.uk/Ortygia.dx6182482)[Hotels in Ortygia](https://expedia.co.uk/Ortygia-Hotels.d6182482.Travel-Guide-Hotels)[Holiday Rentals in Ortygia](https://expedia.co.uk/Ortygia-Holiday-Rentals.d6182482.Travel-Guide-HolidayRentals)[Flights to Ortygia](https://expedia.co.uk/Cheap-Flights-To-Ortygia.d6182482.Travel-Guide-Flights)[Things to do in Ortygia](https://expedia.co.uk/Things-To-Do-In-Ortygia.d6182482.Travel-Guide-Activities)[Ortygia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Ortygia.d6182482.Car-Hire-Guide)[Ortygia Holidays](https://expedia.co.uk/Ortygia.d6182482.Holidays-City-Breaks) ![Ortygia featuring street scenes and markets as well as a small group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87652-Ortygia.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Ortygia - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Ortygia Business Hotels Tonight [4 Nov - 5 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [5 Nov - 6 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6182482&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Ortygia Business Hotels ![Front of property – evening/night](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d402c8e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free minibar, in-room safe, individually decorated, desk](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/ea1a8843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/dc8ba8c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/a8772cd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Algila' Ortigia Charme Hotel Ortigia 9.6/10 Exceptional (892) "The breakfast was delicious, the staff impeccable and the room delightful. All in all an excellent stay which I would wholeheartedly recommend. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Sarah [](https://www.expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![Panoramic Room | Water view](https://images.trvl-media.com/lodging/3000000/2530000/2527300/2527263/fe44f2b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/3000000/2530000/2527300/2527263/e8c92616.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Room | View from property](https://images.trvl-media.com/lodging/3000000/2530000/2527300/2527263/e143e0d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/3000000/2530000/2527300/2527263/eb6c6044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### L'Approdo delle Sirene Ortigia 9.0/10 Wonderful (278) "A very warm and hospitable stay! Great staff, spacious room and amazing location. Absolutely recommend staying here! " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Tatiana [](https://www.expedia.co.uk/Syracuse-Hotels-LApprodo-Delle-Sirene.h2527263.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/206c3f7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach nearby, black sand, beach shuttle, sun-loungers](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/1d01df07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch served; international cuisine, al fresco dining ](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/cc080552.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food court](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/345642c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Ortigia Siracusa Ortigia 9.0/10 Wonderful (564) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Liza £163 includes taxes & fees 20 Nov - 21 Nov [](https://www.expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) ![Junior Suite, Terrace | Terrace/patio](https://images.trvl-media.com/lodging/19000000/18330000/18327700/18327666/047f66fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 8 per person)](https://images.trvl-media.com/lodging/19000000/18330000/18327700/18327666/fa1565cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18330000/18327700/18327666/24e33a10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room | View from room](https://images.trvl-media.com/lodging/19000000/18330000/18327700/18327666/7037c168.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dimore delle Zagare Ortigia Ortigia 9.8/10 Exceptional (158) "Modern and clean. Friendly, sweet and attentive staff. Great location. Thoroughly enjoyed our stay here. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Steven [](https://www.expedia.co.uk/Syracuse-Hotels-Dimore-Delle-Zagare-Ortigia.h18327666.Hotel-Information) ![Free daily cooked-to-order breakfast ](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/235f3413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/6baaad51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down duvets, minibar, desk](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/a757828a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/917800/917761/cb884c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Posta Ortigia 8.4/10 Very good (449) "Hotel Posta is the perfect small hotel in a great location. If you have a car the public parking is steps away, walking around is a breeze. So many great restaurants. My room was perfect, roof top terrace, breakfast and a very friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacquelin £78 includes taxes & fees 19 Nov - 20 Nov [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Posta.h917761.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fcb5d184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, Balcony, Ocean View | Select Comfort beds, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/49c0552c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/284340c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fe8a6bf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Domus Mariae Albergo Ortigia 9.2/10 Wonderful (330) "Great location, but very average accommodation. The bed was comfortable, but there were no real amenities like coffee or water available in the rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) clint £127 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) ![Family Twin Room | Hypo-allergenic bedding, down duvets, memory-foam beds, minibar](https://images.trvl-media.com/lodging/90000000/89730000/89720300/89720229/c316beda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89730000/89720300/89720229/7757fd29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room | Hypo-allergenic bedding, down duvets, memory-foam beds, minibar](https://images.trvl-media.com/lodging/90000000/89730000/89720300/89720229/da8fa3e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/90000000/89730000/89720300/89720229/937fd42a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Joy's BnB Ortigia Ortigia 9.4/10 Exceptional (22) "Great hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angie Samantha [](https://www.expedia.co.uk/Syracuse-Hotels-Xenia.h89720229.Hotel-Information) ![Building design](https://images.trvl-media.com/lodging/1000000/980000/976400/976389/c9e03ff2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/980000/976400/976389/cbf3a060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/980000/976400/976389/30aef09f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/980000/976400/976389/3abb85fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Hotel Des Ètrangers - The Leading Hotels of the World Ortigia 9.6/10 Exceptional (73) "Great hotel in a fantastic location. Staff very helpful.Beautiful pool with great views. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane £419 includes taxes & fees 6 Nov - 7 Nov [](https://www.expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Des-Etrangers.h976389.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/b9e3b8e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/27da8058.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/f325b30d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2540000/2535900/2535838/2f13634a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Gutkowski Ortigia 8.8/10 Excellent (127) "Nice room with ocean view, helpful staff, the nearby market is very interesting " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sarah Shan £79 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Syracuse-Hotels-Hotel-Gutkowski.h2535838.Hotel-Information) ![Jetted bathtub](https://images.trvl-media.com/lodging/118000000/117890000/117886400/117886322/6882006d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/118000000/117890000/117886400/117886322/eb122c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, Bay View | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/118000000/117890000/117886400/117886322/59e9961a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/118000000/117890000/117886400/117886322/0bec1b6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Dimora di San Nicola Ortigia 10/10 Exceptional (1) £367 includes taxes & fees 7 Nov - 8 Nov [](https://www.expedia.co.uk/Syracuse-Hotels-La-Dimora-Di-San-Nicola.h117886322.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19®ionId=6182482&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Ortygia Hotel Reviews ![Grand Hotel Ortigia Siracusa](//images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/206c3f7f_y.jpg) ### Grand Hotel Ortigia Siracusa 10/10 Excellent "breakfast was good" [](https://expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) ![Domus Mariae Albergo](//images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/fcb5d184_y.jpg) ### Domus Mariae Albergo 10/10 Excellent "Lovely staff. Great view. Good location." [](https://expedia.co.uk/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) ![Algila' Ortigia Charme Hotel](//images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d402c8e9_y.jpg) ### Algila' Ortigia Charme Hotel 10/10 Excellent "A beautiful hotel, across from the sea. Can walk thru the beautiful streets of Ortigia. Highly recommend." [](https://expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![Palazzo Artemide - VRetreats](//images.trvl-media.com/lodging/1000000/980000/974100/974007/5db9500b_y.jpg) ### Palazzo Artemide - VRetreats 10/10 Excellent "Very courteous staff. Excellent location close to everything. Room was modern and clean. Highly recommend." [](https://expedia.co.uk/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information) ![Grand Hotel Des Ètrangers - The Leading Hotels of the World](//images.trvl-media.com/lodging/1000000/980000/976400/976389/c9e03ff2_y.jpg) ### Grand Hotel Des Ètrangers - The Leading Hotels of the World 10/10 Excellent "Great hotel and saff" [](https://expedia.co.uk/Syracuse-Hotels-Grand-Hotel-Des-Etrangers.h976389.Hotel-Information) ![Charme Hotel Henry's House](//images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/f02c4712_y.jpg) ### Charme Hotel Henry's House 10/10 Excellent "Excellent all around .. a gem " [](https://expedia.co.uk/Syracuse-Hotels-Charme-Hotel-Henrys-House.h7797247.Hotel-Information) ![Ortea Palace Hotel, Sicily, Autograph Collection](//images.trvl-media.com/lodging/18000000/17830000/17825900/17825841/3b8d7262_y.jpg) ### Ortea Palace Hotel, Sicily, Autograph Collection 10/10 Excellent "Everything is excellent, except the shower which is very small and uncomfortable which makes it impossible to enjoy the bath." [](https://expedia.co.uk/Syracuse-Hotels-Ortea-Palace-Luxury-Hotel.h17825841.Hotel-Information) ![Alla Giudecca](//images.trvl-media.com/lodging/2000000/1760000/1759000/1758948/02859755_y.jpg) ### Alla Giudecca 10/10 Excellent "We loved the history of the building, it was beautiful. Spacious rooms with outside sitting area. Walkable to all areas of interest in Ortigia and cafes and restaurants. Staff were helpful. " [](https://expedia.co.uk/Syracuse-Hotels-Alla-Giudecca.h1758948.Hotel-Information) ![Hotel Posta](//images.trvl-media.com/lodging/1000000/920000/917800/917761/235f3413_y.jpg) ### Hotel Posta 10/10 Excellent "Great location, easy walking to most everywhere. Great hotel that feels like Sicily! Staff extremely helpful. Breakfast more than adequate. 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