Title: TOP Boutique Hotels in Syracuse for 2025 | Expedia.co.uk [Syracuse Travel Guide](https://expedia.co.uk/Syracuse.dx4912)[Hotels in Syracuse](https://expedia.co.uk/Syracuse-Hotels.d4912.Travel-Guide-Hotels)[Holiday Rentals in Syracuse](https://expedia.co.uk/Syracuse-Holiday-Rentals.d4912.Travel-Guide-HolidayRentals)[Flights to Syracuse](https://expedia.co.uk/Cheap-Flights-To-Syracuse.d4912.Travel-Guide-Flights)[Things to do in Syracuse](https://expedia.co.uk/Things-To-Do-In-Syracuse.d4912.Travel-Guide-Activities)[Syracuse Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Syracuse.d4912.Car-Hire-Guide)[Syracuse Holidays](https://expedia.co.uk/Syracuse.d4912.Holidays-City-Breaks) ![Syracuse which includes street scenes as well as an individual female](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/87000/87499-Syracuse.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in Syracuse ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Syracuse Boutique Hotels Tonight [14 Oct - 15 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=4912&startDate=2025-10-14&endDate=2025-10-15&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [15 Oct - 16 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=4912&startDate=2025-10-15&endDate=2025-10-16&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=4912&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=4912&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Syracuse Boutique Hotels ![Classic Double Room, Partial Sea View | View from room](https://images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/f02c4712.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/4e4f954f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Double Room, Sea View | 1 bedroom, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/4e88f169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/947b1b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charme Hotel Henry's House Ortigia 9.6/10 Exceptional (316) "Wonderful place to stay!" £227 includes taxes & fees 12 Nov - 13 Nov [](https://www.expedia.co.uk/Syracuse-Hotels-Charme-Hotel-Henrys-House.h7797247.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-27&endDate=2025-10-28®ionId=4912&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Syracuse Hotel Reviews ![Algila' Ortigia Charme Hotel](//images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d402c8e9_y.jpg) ### Algila' Ortigia Charme Hotel 10/10 Excellent "We really enjoyed this property. The buildings are ancient, but completely renovated and clean. Bathrooms are new, beds are comfortable with good linens. Breakfasts are excellent with many choices. " [](https://expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![Charme Hotel Henry's House](//images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/f02c4712_y.jpg) ### Charme Hotel Henry's House 10/10 Excellent "Beautiful property. Perfect location. Outstanding service. Comfortable bed. " [](https://expedia.co.uk/Syracuse-Hotels-Charme-Hotel-Henrys-House.h7797247.Hotel-Information) ## Frequently asked questions ### What's the best boutique-style hotel in Syracuse? > [Charme Hotel Henry's House](https://www.expedia.co.uk/Syracuse-Hotels-Charme-Hotel-Henrys-House.h7797247.Hotel-Information) is a favourite hotel with our travellers looking for stylish accommodation, and features 14 guestrooms, free breakfast and a rooftop terrace. ### What's there to see and do in Syracuse? > The ocean views, historic landmarks and archaeological sites are just some of the things to enjoy while you're in the area. Attractions and activities to experience around Syracuse include Temple of Apollo, Lungomare di Ortigia and Piazza del Duomo. Some other things you might want to enjoy include Teatro dei Pupi, Arkimedeion Museum and Syracuse Municipal Theater. ### What kind of weather should I plan for when I travel to Syracuse? > Understanding the weather in Syracuse is important when planning your trip. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for Syracuse is 653 mm. ### What's the best way to get to my boutique hotel in Syracuse? > You have a few options for getting to Syracuse. The closest major airport is Catania (CTA-Fontanarossa), which is located 30.7 mi (49.5 km) from the heart of the city. 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