Title: TOP Boutique Hotels in Syracuse for 2025 | Expedia.co.uk [Syracuse Travel Guide](https://expedia.co.uk/Syracuse.dx4912)[Hotels in Syracuse](https://expedia.co.uk/Syracuse-Hotels.d4912.Travel-Guide-Hotels)[Holiday Rentals in Syracuse](https://expedia.co.uk/Syracuse-Holiday-Rentals.d4912.Travel-Guide-HolidayRentals)[Flights to Syracuse](https://expedia.co.uk/Cheap-Flights-To-Syracuse.d4912.Travel-Guide-Flights)[Things to do in Syracuse](https://expedia.co.uk/Things-To-Do-In-Syracuse.d4912.Travel-Guide-Activities)[Syracuse Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Syracuse.d4912.Car-Hire-Guide)[Syracuse Holidays](https://expedia.co.uk/Syracuse.d4912.Holidays-City-Breaks) ![Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe](https://images.trvl-media.com/place/4912/0fad57c8-f045-437c-be3c-817a684ac32e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in Syracuse - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Syracuse Boutique Hotels Tonight [29 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=4912&startDate=2025-11-29&endDate=2025-11-30&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [30 Nov - 1 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=4912&startDate=2025-11-30&endDate=2025-12-01&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=4912&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=4912&startDate=2025-12-12&endDate=2025-12-14&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Syracuse Boutique Hotels ![Classic Double Room, Partial Sea View | View from room](https://images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/f02c4712.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City view from property](https://images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/947b1b05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Double Room, Sea View | 1 bedroom, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/4e88f169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/8000000/7800000/7797300/7797247/4e4f954f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charme Hotel Henry's House Ortigia 9.6/10 Exceptional (322) "Great location. Very friendly and helpful staff. Nice breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alan £222 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Syracuse-Hotels-Charme-Hotel-Henrys-House.h7797247.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-13&endDate=2025-12-14®ionId=4912&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_BF_PROMO_4912) ## Top Syracuse Hotel Reviews ![Palazzo Artemide - VRetreats](https://images.trvl-media.com/lodging/1000000/980000/974100/974007/5db9500b_y.jpg) ### Palazzo Artemide - VRetreats 10/10 Excellent "Great service……………" [](https://expedia.co.uk/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information) ![Algila' Ortigia Charme Hotel](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/d402c8e9_y.jpg) ### Algila' Ortigia Charme Hotel 10/10 Excellent "Great location. Helpful staff. Nice breakfasts. " [](https://expedia.co.uk/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ## Frequently asked questions ### What's the best boutique-style hotel in Syracuse? > [Charme Hotel Henry's House](https://www.expedia.co.uk/Syracuse-Hotels-Charme-Hotel-Henrys-House.h7797247.Hotel-Information) is a favourite hotel with our travellers looking for stylish accommodation, and features 14 guestrooms, free breakfast and a rooftop terrace. ### What's there to see and do in Syracuse? > The ocean views, historic landmarks and archaeological sites are just some of the things to enjoy while you're in the area. Attractions and activities to experience around Syracuse include Temple of Apollo, Lungomare di Ortigia and Piazza del Duomo. Some other things you might want to enjoy include Teatro dei Pupi, Syracuse Municipal Theater and Papyrus Museum. ### What kind of weather should I plan for when I travel to Syracuse? > Understanding the weather in Syracuse is important when planning your trip. The hottest months are usually August and July, with an average temperature of 25°C, while the coldest months are February and January, with an average of 14°C. Average annual precipitation for Syracuse is 653 mm. ### What's the best way to get to my boutique hotel in Syracuse? > You have a few options for getting to Syracuse. The closest major airport is Catania (CTA-Fontanarossa), which is located 30.7 mi (49.5 km) from the heart of the city. 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