Are there any 5-star all-inclusive resorts in Syracuse?

Use our convenient filters to find a high-end escape in Syracuse where most of what you need is included. From there, narrow your results for resorts that have a 5-star rating and are deemed "All inclusive." The first thing on the to-do list at these stays? Relaxation and enjoyment.

What are the top 5-star spa hotels in Syracuse?

Enjoy a spa holiday at Minareto and let your worries melt away. Ortea Palace Hotel, Sicily, Autograph Collection and Grand Hotel Ortigia Siracusa are other 5-star accommodation in Syracuse where you can indulge in therapeutic and soothing benefits of wellness programmes and spa treatments.

Are there any 5-star holiday rentals in Syracuse?

Although there aren't any 5-star holiday rentals in Syracuse on our site, we have a range of retreats that promise a terrific getaway. Find one that matches your needs by searching our holiday rentals in Syracuse .

Are there any 5-star hotels in downtown Syracuse?

Book a room at Grand Hotel Ortigia Siracusa . This 5-star hotel is an excellent option if you want to immerse yourself in Syracuse's buzzing downtown scene.

The 10 Best 5 Star Hotels in Syracuse - 2026 Updated Prices

Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe

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Our top choices for Syracuse 5-star hotels

Grand Hotel Ortigia Siracusa

Ortigia

Yuqi

includes taxes & fees

28 May - 29 May

Ortea Palace Hotel, Sicily, Autograph Collection

Ortigia

Max

includes taxes & fees

4 Jun - 5 Jun

Caportigia Boutique Hotel

Santa Lucia

Borna

includes taxes & fees

28 May - 29 May

Sauna, hot tub, Turkish bath/hammam, body treatments, body scrubs

Dimora Caiammari Luxury Hotel & Spa

Syracuse

Jing

includes taxes & fees

20 Jun - 21 Jun

Seasonal outdoor pool, pool umbrellas, pool loungers

Grand Hotel Des Ètrangers - The Leading Hotels of the World

Ortigia

Dena

includes taxes & fees

2 Jun - 3 Jun

Minareto

Syracuse

Stanislau

includes taxes & fees

3 Jun - 4 Jun

Wellness & Spa Hotel Principe di Fitalia

Syracuse

Jeffrey

includes taxes & fees

9 Jun - 10 Jun

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Syracuse.

Algila' Ortigia Charme Hotel

Via Vittorio Veneto 93 Syracuse SR

£281

23 Jun - 24 Jun

includes taxes & fees

9.6/10 Exceptional! (959 reviews)

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Syracuse

Ancient Greek ruins in the Archaeological Park include the impressive Teatro Greco where summer performances still take place. Wander through Ortygia's narrow streets to discover the Duomo, built around a former Greek temple with columns still visible from inside.

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Top Syracuse Hotel Reviews

Grand Hotel Des Ètrangers - The Leading Hotels of the World

8/10 Good

"We were a bit disappointed with our stay at Grand Hotel des Étrangers. While the hotel has been beautifully renovated and is in very good condition, it felt more like a generic luxury hotel and lacked the Sicilian character we were hoping for. The breakfast room also felt somewhat “hotel-like,” although the breakfast itself was delicious. The staff were consistently friendly and helpful, and we especially loved the pool, which was heated to a very comfortable 28°C. The spa was also lovely, although it was frustrating that we were only told about the beautiful recovery room after our treatments were finished and we had already changed. The outdoor rooftop bar was lovely as well with comfy couches and a great view. There were a few downsides that made the stay feel overpriced for what we received. Parking at the hotel costs €50 per day, but we found the public Talete lot nearby for only €15. Our room was quite basic and very small, facing an alley where there was constant noise from dumpsters being emptied. For roughly $1,000 per night, we expected much more. Another issue was the loud music from the beach club on the ground floor, especially in the late afternoon and evening. We’re also not convinced it’s worth paying a premium for a sea-view upgrade, as the views over Siracusa are pleasant but not particularly spectacular. Overall, the hotel has some strong points, but for the price, we expected a more special and authentic experience."