Default HTG hotel image

Search Hotels in Mayo Clinic, Phoenix

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Mayo Clinic hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.4 out of 10, Very good, (1,086 reviews)
"Very nice accommodations"
United States
Michael
The price is £77
includes taxes & fees
18 Oct - 19 Oct
Sonesta Select Scottsdale at Mayo Clinic Campus
A cluster of modern, multi-story buildings with a river in the foreground.

2. Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
1.9 mi from Mayo Clinic
9.0 out of 10, Wonderful, (1,026 reviews)
"We loved our stay, beautiful location. Room was lovely, the hot tub view was gorgeous, and location was perfect for exploring and a quiet get away."
United States
Shelby
The price is £114
includes taxes & fees
25 Oct - 26 Oct
Inn at Eagle Mountain
A spacious living area with a kitchen, modern furniture, and a fireplace.

3. Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
3.0 star property
4.5 mi from Mayo Clinic
9.0 out of 10, Wonderful, (1,004 reviews)
"Great hotel to stay"
United States
Guadalupe
The price is £94
includes taxes & fees
18 Oct - 19 Oct
Fountain Park Hotel, BW Signature Collection
A hotel lobby with a reception desk, seating area, and a large wall mural.

4. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 5.6 mi from Mayo Clinic
8.8 out of 10, Excellent, (1,863 reviews)
"Clean rooms, good hot breakfast, location is good, close to many restaurants and good freeway access. But best of all is the very help front desk staff."
United States
Paul
The price is £73
includes taxes & fees
25 Oct - 26 Oct
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

5. Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
5.5 mi from Mayo Clinic
9.0 out of 10, Wonderful, (1,181 reviews)
"Easy check in, and check out."
United States
PATRICK
The price is £88
includes taxes & fees
28 Oct - 29 Oct
Aiden by Best Western Scottsdale North
A hotel room with two beds, a desk with a chair, a TV, and a lamp.

6. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
2.5 star property
6 mi from Mayo Clinic
9.2 out of 10, Wonderful, (2,055 reviews)
"would definitely stay here again"
United States
LAURA
The price is £94
includes taxes & fees
8 Nov - 9 Nov
Comfort Suites Scottsdale Talking Stick Entertainment District
A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

7. Hyatt House North Scottsdale

Hyatt House North Scottsdale
3.5 star property
8.8 mi from Mayo Clinic
9.6 out of 10, Exceptional, (1,006 reviews)
"We enjoyed our stay. Food, hospitality and the drive was great and convenient."
United States
Slyqavious
The price is £117
includes taxes & fees
25 Oct - 26 Oct
Hyatt House North Scottsdale
An outdoor patio with a fire pit, string lights, and outdoor furniture.

8. Hilton Vacation Club Scottsdale Links Resort

Hilton Vacation Club Scottsdale Links Resort
3.5 star property
7.1 mi from Mayo Clinic
9.2 out of 10, Wonderful, (1,137 reviews)
"Will stay there again in the future"
United States
Jacob
The price is £135
includes taxes & fees
22 Oct - 23 Oct
Hilton Vacation Club Scottsdale Links Resort
A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

9. Best Western Plus Scottsdale Thunderbird Suites

Best Western Plus Scottsdale Thunderbird Suites
3.0 star property
Thunderbird Industrial Airpark, 7.6 mi from Mayo Clinic
8.6 out of 10, Excellent, (1,000 reviews)
"Love the lounge with the bar and the breakfast was the best!!"
United States
Susan
The price is £104
includes taxes & fees
25 Oct - 26 Oct
Best Western Plus Scottsdale Thunderbird Suites
A lounge area with a curved seating arrangement, a staircase, and a view of an outdoor pool.

10. The McCormick Scottsdale

The McCormick Scottsdale
3.5 star property
8.1 mi from Mayo Clinic
8.4 out of 10, Very good, (1,326 reviews)
"Staff was very helpful and courteous"
United States
Marsha
The price is £132
includes taxes & fees
15 Oct - 16 Oct
The McCormick Scottsdale
An outdoor dining area with wicker furniture and candles, overlooking a well-maintained garden and buildings.

11. Sonesta Suites Scottsdale Gainey Ranch

Sonesta Suites Scottsdale Gainey Ranch
3.5 star property
7.7 mi from Mayo Clinic
9.0 out of 10, Wonderful, (1,077 reviews)
"We enjoyed the pool after a long drive."
United States
Cindy
The price is £150
includes taxes & fees
2 Nov - 3 Nov
Sonesta Suites Scottsdale Gainey Ranch
An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

12. Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
6.3 mi from Mayo Clinic
9.2 out of 10, Wonderful, (1,009 reviews)
"Wonderful resort!"
United States
jennifer
The price is £131
includes taxes & fees
18 Oct - 19 Oct
Wekopa Casino Resort
A hotel lobby with a geometric floor pattern, a chandelier, and a mountain view mural.

13. Embassy Suites by Hilton Scottsdale Resort

Embassy Suites by Hilton Scottsdale Resort
3.5 star property
9.3 mi from Mayo Clinic
8.6 out of 10, Excellent, (1,344 reviews)
"Wonderful stay"
United States
Kizito
The price is £142
includes taxes & fees
21 Oct - 22 Oct
Embassy Suites by Hilton Scottsdale Resort
A hotel room with a red sofa, a wooden dining table set for two, a television, and a patterned carpet.

14. Sonesta Simply Suites Phoenix Scottsdale

Sonesta Simply Suites Phoenix Scottsdale
2.5 star property
5.4 mi from Mayo Clinic
7.8 out of 10, Good, (1,003 reviews)
"Priced Fair. Cable TV gets boring. Microwave and utensils are nice"
United States
STEVEN
The price is £80
includes taxes & fees
8 Nov - 9 Nov
Sonesta Simply Suites Phoenix Scottsdale
A hotel lobby with a reception desk, seating area, and large windows.

15. The Azure Hotel

The Azure Hotel
2.5 star property
11.9 mi from Mayo Clinic
8.8 out of 10, Excellent, (2,004 reviews)
"Always a good stay at this property"
United States
Heather
The price is £62
includes taxes & fees
14 Oct - 15 Oct
The Azure Hotel
A modern hotel with a brick facade, large windows, and a covered entrance area.

16. Springhill Suites Phoenix Scottsdale Marriott

Springhill Suites Phoenix Scottsdale Marriott
2.0 star property
11.4 mi from Mayo Clinic
9.4 out of 10, Exceptional, (446 reviews)
"Helpful staff and great amenities."
United States
Marie
The price is £102
includes taxes & fees
25 Oct - 26 Oct
Springhill Suites Phoenix Scottsdale Marriott
A pool area with multiple swimming pools, lounge chairs, and potted plants.

17. Fairfield Inn & Suites by Marriott Tempe

Fairfield Inn & Suites by Marriott Tempe
3.0 star property
12.6 mi from Mayo Clinic
9.6 out of 10, Exceptional, (447 reviews)
"We will stay here again next time we come into town. Everything was clean and kept up. The breakfast was good too!"
United States
DeAnna
The price is £89
includes taxes & fees
8 Nov - 9 Nov
Fairfield Inn & Suites by Marriott Tempe
An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

18. Hyatt Place Scottsdale - North

Hyatt Place Scottsdale - North
3.0 star property
8.8 mi from Mayo Clinic
9.2 out of 10, Wonderful, (1,277 reviews)
"Clean rooms, friendly staff, good breakfast spread."
United States
Ted
The price is £113
includes taxes & fees
25 Oct - 26 Oct
Hyatt Place Scottsdale - North
A hotel reception area with a stone counter, a staircase, and a hallway leading to other rooms.

19. SureStay Plus by Best Western Mesa Superstition Springs

SureStay Plus by Best Western Mesa Superstition Springs
2.5 star property
14.5 mi from Mayo Clinic
8.2 out of 10, Very good, (1,860 reviews)
"Good for solo traveler"
United States
Joshua
The price is £57
includes taxes & fees
14 Oct - 15 Oct
SureStay Plus by Best Western Mesa Superstition Springs
An indoor water park with slides, a wave pool, and seating areas.

20. Great Wolf Lodge Arizona

Great Wolf Lodge Arizona
4.0 star property
6.4 mi from Mayo Clinic
8.8 out of 10, Excellent, (1,007 reviews)
"Loved everything about our stay!"
United States
Dejanira
The price is £141
includes taxes & fees
3 Nov - 4 Nov
Great Wolf Lodge Arizona
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas for the activities you enjoy most.
A cityscape with prominent buildings including a Chase bank and The Arizona Republic building.

Downtown Phoenix

Cheer on the Phoenix Suns at an NBA game or walk around the city’s historic precinct as you explore the state capital.

A fountain with three horses, surrounded by red flowers and storefronts.

Old Town

Gourmet restaurants interesting history and top sights from Scottsdale Waterfront to Western Spirit: Scottsdale's Museum of the West – discover Old Town, a destination also famous for its shopping.

A hiker on a rocky trail with mountains in the background.

Rio Verde Foothills

If you're looking for some top things to see and do in Rio Verde Foothills and surrounding area, you can visit Golf Club Scottsdale and Tom's Thumb Trail.

A rocky hill with palm trees and a body of water.

Camelback East

You might take some time to check out the abundant dining options in Camelback East. Spend some time visiting top spots like Biltmore Fashion Park, and catch the metro at 44th Street - Washington Station or 50th Street Station to see more of the area.

A mountainous landscape with a city in the valley below.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

Top Mayo Clinic Hotel Reviews

DoubleTree Resort by Hilton Paradise Valley - Scottsdale

DoubleTree Resort by Hilton Paradise Valley - Scottsdale

10/10 Excellent
"Nice"
Dr. Tiffany 1-night trip
Posted 3 hours ago
DoubleTree Resort by Hilton Paradise Valley - Scottsdale

Frequently asked questions

What are the best hotels in Mayo Clinic that travellers recommend?
For a highly recommended hotel in Mayo Clinic, consider the Sonesta Select Scottsdale at Mayo Clinic Campus.

This 3-star hotel has an 8.2 rating and is praised by guests for its comfortable, clean rooms and friendly, helpful staff. Its location is perfect, being just 0.3 km from Mayo Clinic Scottsdale. Guests also appreciate the easy parking and comfortable beds. The hotel offers an outdoor pool, a hot tub, and premium bedding for a restful stay.
What are the best family hotels in Mayo Clinic?
For families visiting Mayo Clinic, the Sonesta Select Scottsdale at Mayo Clinic Campus is a highly recommended option.

This 3-star hotel, with an 8.2 rating, is praised by guests for its comfortable and clean rooms, as well as its friendly and helpful staff. Families will appreciate the availability of free cribs, rollaway extra beds, and sofa beds, ensuring everyone has a comfortable stay. Connecting rooms are also an option for larger families. For those who enjoy outdoor activities, mountain biking is available at a nearby location. Guests also highlight the great and beautiful location, along with easy parking, making it a convenient choice for families.
What are the top pet-friendly hotels in Mayo Clinic?
For top pet-friendly accommodation in Mayo Clinic, the Sonesta Select Scottsdale at Mayo Clinic Campus is an excellent choice.

This 3-star hotel, with an 8.2 rating, warmly welcomes both dogs and cats, making it a great spot for travellers with furry companions. Guests frequently highlight the comfortable and clean rooms, as well as the friendly and helpful staff. The location is described as great and beautiful, offering a pleasant stay for both you and your pets. The hotel also provides food and water bowls, ensuring your pets have everything they need. Additionally, guests appreciate the easy parking, adding to the convenience of your visit.
What are the best budget hotels in Mayo Clinic?
For a budget-friendly hotel near Mayo Clinic, the Sonesta Select Scottsdale at Mayo Clinic Campus is an excellent option.

This 3-star hotel has an 8.2 rating and offers comfortable, clean rooms with free internet and complimentary toiletries. Guests frequently praise the friendly, helpful staff and the perfect, beautiful location, as well as the easy parking and comfortable beds.
What are the most romantic hotels in Mayo Clinic for couples?
For couples seeking a romantic getaway in Mayo Clinic, the Sonesta Select Scottsdale at Mayo Clinic Campus is a highly-rated option.

This 3-star hotel, with an 8.2 rating, is often praised by guests for its comfortable and clean rooms, as well as its friendly and helpful staff. Its beautiful location and easy parking contribute to a relaxing stay. The hotel also features a hot tub, great for unwinding together, and offers free internet and WiFi.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mayo Clinic.
How much is the nightly rate at a Mayo Clinic hotel?
Hotel prices in Mayo Clinic often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

Explore a world of travel with Expedia