Title: The Best Hotels in Matlacha Isles, Cape Coral - 2026 Updated Prices | Expedia.co.uk [Holiday Rentals in Cape Coral](https://expedia.co.uk/Cape-Coral-Holiday-Rentals.d6521.Travel-Guide-HolidayRentals)[Flights to Cape Coral](https://expedia.co.uk/Cheap-Flights-To-Cape-Coral.d6521.Travel-Guide-Flights)[Things to do in Cape Coral](https://expedia.co.uk/Things-To-Do-In-Cape-Coral.d6521.Travel-Guide-Activities)[Matlacha Isles Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Matlacha-Isles.d553248635976471942.Car-Hire-Guide)[Matlacha Isles Holidays](https://expedia.co.uk/Matlacha-Isles.d553248635976471942.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Matlacha Isles, Cape Coral - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [8 Jan - 9 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976471942&startDate=2026-01-08&endDate=2026-01-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [9 Jan - 10 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976471942&startDate=2026-01-09&endDate=2026-01-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976471942&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976471942&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Matlacha Isles hotels ![3 restaurants, breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/9bc89705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite with Two Doubles, Beachfront, Balcony | Individually decorated, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/2e8856cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/6ac4649e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio with Two Doubles, Beachfront, Balcony | Individually decorated, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/3202bde7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lani Kai Beachfront Resort [](https://www.expedia.co.uk/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) 14.4 mi from Matlacha Isles 9.0/10 Wonderful (1093) "Clean rooms lovely view of Beach and pool area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laurice-Larry £150 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/9c00e0a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/7fb404a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/b80b1ff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4520000/4513100/4513051/824d933b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Punta Gorda/Port Charlotte [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Baymont-By-Wyndham-Punta-GordaPort-Charlotte.h4513051.Hotel-Information) 18 mi from Matlacha Isles 8.4/10 Very good (1157) "Friendly staff, good breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom £74 includes taxes & fees 9 Jan - 10 Jan [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Baymont-By-Wyndham-Punta-GordaPort-Charlotte.h4513051.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/46330a76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/d3248701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/a840448a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/1fa522a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park [](https://www.expedia.co.uk/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) 17.4 mi from Matlacha Isles 8.0/10 Very good (1538) "Loved the stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Moosa Nazar £69 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/de6b5b90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/d96dd9cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/3ed2496c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/23000000/22500000/22492300/22492255/d3615161.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Punta Gorda by IHG [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Holiday-Inn-Express-And-Suites-Punta-Gorda.h22492255.Hotel-Information) 17.9 mi from Matlacha Isles 9.4/10 Exceptional (1000) "Clean room, good location, reasonable price." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £102 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Holiday-Inn-Express-And-Suites-Punta-Gorda.h22492255.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/3bf7e12d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Queen Suite Two Queen Beds | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/74c618a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, stovetop](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/01114515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/104000000/103190000/103186900/103186827/0afa75e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Fort Myers - Cape Coral [](https://www.expedia.co.uk/Fort-Myers-Hotels-Woodspring-Suites-Fort-Myers-Cape-Coral.h103186827.Hotel-Information) 11.3 mi from Matlacha Isles 7.2/10 Good (156) "The service at the front desk was exceptional, the new manager is doing an amazing job!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandro £73 includes taxes & fees 9 Jan - 10 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Woodspring-Suites-Fort-Myers-Cape-Coral.h103186827.Hotel-Information) ![Laptop workspace, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114950000/114942200/114942118/cf5bc44c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114950000/114942200/114942118/a228a358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114950000/114942200/114942118/53b2f3fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114950000/114942200/114942118/b6642010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### StudioRes Fort Myers Airport [](https://www.expedia.co.uk/Fort-Myers-Hotels-Studiores-Fort-Myers.h114942118.Hotel-Information) 18.4 mi from Matlacha Isles 9.2/10 Wonderful (24) "Loved stay here!!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melissa £84 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Studiores-Fort-Myers.h114942118.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/2deb021c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/6f1c6d7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/a683180f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1750000/1746300/1746276/eec3b567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Fort Myers Airport [](https://www.expedia.co.uk/Fort-Myers-Hotels-Comfort-Inn-Suites-Airport.h1746276.Hotel-Information) 17.3 mi from Matlacha Isles 8.8/10 Excellent (1112) "Comfortable rooms and beds, good breakfast and easy access to baseball parks." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier £81 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Comfort-Inn-Suites-Airport.h1746276.Hotel-Information) ![Floating Coconut Cottage Houseboat | Terrace/patio](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/1830d2aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:30 AM to 9:30 PM, free pool cabanas, pool loungers](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/bf04ece4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Floating Coconut Cottage Houseboat | Living area | Smart TV, Hulu, streaming services](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/65803bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Floating Coconut Cottage Houseboat | Premium bedding, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/6000000/5110000/5107300/5107225/0badd225.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Resort & Marina [](https://www.expedia.co.uk/Fort-Myers-Hotels-Tip-Top-Isles-Waterfront-Resort-Marina.h5107225.Hotel-Information) 12.6 mi from Matlacha Isles 8.6/10 Excellent (913) "Staff was very helpful at check-in; room was clean. As a solo female traveler, I felt safe. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly [](https://www.expedia.co.uk/Fort-Myers-Hotels-Tip-Top-Isles-Waterfront-Resort-Marina.h5107225.Hotel-Information) ![Sun deck](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/2c59b397.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Kayaking](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/94b7632c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/8bc2b39a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, Kitchen, Pool View | Living area | TV](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/763b4722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Boutique Resort - Fort Myers Beach [](https://www.expedia.co.uk/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) 12.7 mi from Matlacha Isles 8.8/10 Excellent (1000) "Great Place to Stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JUDY £108 includes taxes & fees 10 Jan - 11 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/5f870412.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/7cc18ae8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/42212932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/f6f6cea7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Fort Myers Inn & Suites [](https://www.expedia.co.uk/Fort-Myers-Hotels-Best-Western-Fort-Myers-Inn-Suites.h17131.Hotel-Information) 12.9 mi from Matlacha Isles 8.8/10 Excellent (1128) "Clean room, old property and fresh, varied options for breakfast" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) supriya £74 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Best-Western-Fort-Myers-Inn-Suites.h17131.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/18000000/17240000/17238900/17238826/6e0e9983.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/18000000/17240000/17238900/17238826/60e66959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed | Down duvets, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/18000000/17240000/17238900/17238826/66852202.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/18000000/17240000/17238900/17238826/2e281d38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boca Grande Hotel [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Boca-Grande-Hotel.h17238826.Hotel-Information) 17.9 mi from Matlacha Isles 8.8/10 Excellent (587) "This place was awesome!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dharyl £121 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Boca-Grande-Hotel.h17238826.Hotel-Information) ![On the beach, sun-loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/f97bdde8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/aa9b23b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun-loungers, beach towels](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/6b3a0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanibel Island Beach Resort [](https://www.expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) 14.1 mi from Matlacha Isles 9.2/10 Wonderful (1520) "Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip £216 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/3f55519b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/29d24bb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/w5616h3741x0y0-fd66ddcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/0fdbdc99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Fort Myers/at The Forum [](https://www.expedia.co.uk/Fort-Myers-Hotels-Hyatt-Place-Fort-Myersat-The-Forum.h2847745.Hotel-Information) 15.4 mi from Matlacha Isles 8.2/10 Very good (1003) "Friendly staff, good breakfast good location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lily £94 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Hyatt-Place-Fort-Myersat-The-Forum.h2847745.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/a69cd385.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/bd66e5bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/9ecc1017.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible (Communications, Accessible Tub) | Hypo-allergenic bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/50000000/49160000/49152700/49152700/2f0290ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG [](https://www.expedia.co.uk/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) 12.4 mi from Matlacha Isles 9.4/10 Exceptional (1000) "Spotless rooms , great breakfast , courteous staff ! Had a great time !" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arijit £117 includes taxes & fees 10 Jan - 11 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Holiday-Inn-Express-Suites-Ft-Myers-Beach-Sanibel-Gateway.h49152700.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/a702090f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking (Upgrade) | Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/3b030475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/54b129e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/f37d87d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Fort Myers East I-75 [](https://www.expedia.co.uk/Fort-Myers-Hotels-Comfort-Suites.h109299203.Hotel-Information) 15.4 mi from Matlacha Isles 9.6/10 Exceptional (370) "Friendly staff, great breakfast, clean room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shellie £86 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Comfort-Suites.h109299203.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/60000/50700/50640/c2f92274.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch LCD TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/60000/50700/50640/02c8f690.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/60000/50700/50640/105102fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![40-inch LCD TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/60000/50700/50640/da383170.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Knights Inn Punta Gorda [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Knights-Inn-Punta-Gorda.h50640.Hotel-Information) 17.7 mi from Matlacha Isles 7.2/10 Good (955) "Very clean and well organized. Staff was professional and well organized, as well." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra £71 includes taxes & fees 9 Jan - 10 Jan [](https://www.expedia.co.uk/Port-Charlotte-Charlotte-Harbor-Hotels-Knights-Inn-Punta-Gorda.h50640.Hotel-Information) ![2 outdoor pools](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/d9487eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast served, al fresco dining ](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/68929405.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Cottage, 1 Queen Bed, Canal View | Living area | 50-inch TV with cable channels](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/4926d47c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/35893057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lighthouse Resort Inn & Suites [](https://www.expedia.co.uk/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) 14.2 mi from Matlacha Isles 8.6/10 Excellent (1594) "Great resort fun bar beautiful pool walkable area variety of restaurants and clean beach" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erika £147 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![1 King Bed Suite w/ Efficiency Non Smoking | Premium bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/8f464d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/f46033d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 King Bed Suite w/ Efficiency Non Smoking | Premium bedding, down duvets, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/a487c18b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24300/24286/2c8820e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Fort Myers Cape Coral [](https://www.expedia.co.uk/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers.h24286.Hotel-Information) 11.4 mi from Matlacha Isles 7.6/10 Good (210) "Clean room and staff was excellent " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) SURINDER £83 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers.h24286.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/7dc3b2fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/37bd8ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/a5e914cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/16900/16889/1ba88bdb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Ft. Myers [](https://www.expedia.co.uk/Fort-Myers-Hotels-Americas-Best-Value-Inn-Ft-Myers.h16889.Hotel-Information) 12 mi from Matlacha Isles 7.6/10 Good (1140) "Loved it. The staff was great rooms were clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Austin £69 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Americas-Best-Value-Inn-Ft-Myers.h16889.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18700/18633/8562a92c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/18700/18633/a75555a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/18700/18633/777d18b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18700/18633/136d0e8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Suites Fort Myers I-75 [](https://www.expedia.co.uk/Fort-Myers-Hotels-Quality-Suites-Fort-Myers-I-75.h18633.Hotel-Information) 16.8 mi from Matlacha Isles 8.2/10 Very good (1001) "Staff was courteous, breakfast was ok, very low water pressure in the shower, room was overall ok." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JUNIOR £83 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/Fort-Myers-Hotels-Quality-Suites-Fort-Myers-I-75.h18633.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-22&endDate=2026-01-23®ionId=553248635976471942&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Matlacha Isles Find the best Matlacha Isles areas for the activities you enjoy most. - Pelican - Caloosahatchee - Yacht Club - Hancock - Mariner ![](https://mediaim.expedia.com/destination/9/350251ac0d9ccc7ca1cb30ed3f0f1512.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/6787174d3f020d364df18c0504ee6a50.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/0db9ea0d958f3eddc014a2724a550e04.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/f6aa46e3ec22aaa67f528102c099f4db.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/0383eed5f73bce5b51600c8b78edb8e2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976481346) ![Pelican map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:oacaDfs%7BsNq_C_z%40an%40al%40m%7B%40sH%7Bo%40dPrGsaGz%40%7DqClLse%40%7C%40se%40fdIbAdSjDhvAeAhg%40t%60B%7CX%7EmEvDdeCswCxcBa%7CAha%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=E70lew0W6sFXzCxHzRLVFKaS8Mg=) ### Pelican While visiting Pelican, you might make a stop by sights like Tarpon Point and Harbour View Gallery. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976481346) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496945-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496204-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496304-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496233-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496139-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635975748682) ![Caloosahatchee map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_l_aDbxisNce%40ImL%7DEg%60Ah%40uvGX%7D%40oaKhPcAlh%40%60nAnc%40dLxl%40qG%7Es%40b%5Bl%5EiGpl%40%60%5D%60PgJnPzZfJvc%40lj%40%7ETx%7E%40vFyBra%40sMlMiPd%60ApPlx%40oFjD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Cya_maxw6zlgfysES9DHBgO1unY=) ### Caloosahatchee If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748682) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976659287) ![Yacht Club map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wo%60aDlwisN%7DGeBsb%40s%5BwJe%5EwIeNzKeXJaI%60HqMH%7D_%40oS%40BuVjEEAwCtLNhCcKhHzDlPbEhOzGxKlC%7EG%7B%40hb%40xAWhKeL%7EViP%60w%40cAdo%40nKvXq%40hFgd%40f%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=9v6IXRj89bAFRtqo7x5Ob4JRxkI=) ### Yacht Club While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Cape Coral Farmers Market are some notable places to visit nearby. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976659287) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/495000/495865-south-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496727-north-fort-myers.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496600-north-fort-myers.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/26729640c04cf35e3216cbbc607fc1c6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/2774ef6de242fcb260ae5796be4d6871.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976420438) ![Hancock map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:oyraDxtmsN_qFusOp%40mwEi%40gBjy%40oaAvI%7EKm%40tPbe%40%60f%40fj%40uGYdI%7BPfH_BnOvJ%7CHxNmH%7ERe%40jBrDyWjUxHzu%40xNlGv%5D%7EBrIfHv_%40lx%40v%5BfLx%60%40bd%40xQhH%60FhIbn%40wGb%5Dm%40hCmGph%40cL%7CCvyF%60%40%7CsFgqA%3FaN%7EAax%40CcNj%40%7B_%40rHuYvK&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=iSHUTH5d48PG0kePXw5a0CSgbnA=) ### Hancock While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976420438) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976470523) ![Mariner map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:etqaDpkssN_oMcA%3FalFkd%40kmAhe%40%3FNgd%40viGlBxHzCfg%40%3Fr%5EgQ%7EeAx%7DClc%40n_BrG%60k%40%7D%40j%60A&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=4CJoAD0sRorEN_B-6JMiJBcI87w=) ### Mariner While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976470523) ## Top Matlacha Isles Hotel Reviews ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "Clean and comfortable room, excellent location to beach,restaurants, shells. Courteous staff" [](https://expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Privacy with own balcony, great breakfast every morning and friendly stuff. " [](https://expedia.co.uk/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![The Westin Cape Coral Resort At Marina Village](https://images.trvl-media.com/lodging/3000000/2730000/2721900/2721880/d961205e_y.jpg) ### The Westin Cape Coral Resort At Marina Village 10/10 Excellent "Outstanding!" [](https://expedia.co.uk/Fort-Myers-Hotels-The-Westin-Cape-Coral-Resort-At-Marina-Village.h2721880.Hotel-Information) ![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "It was our first time there. Would go back. " [](https://expedia.co.uk/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Baymont by Wyndham Fort Myers Central](https://images.trvl-media.com/lodging/1000000/30000/23400/23367/7ff8face_y.jpg) ### Baymont by Wyndham Fort Myers Central 10/10 Excellent "Yes" [](https://expedia.co.uk/Fort-Myers-Hotels-La-Quinta-Inn-By-Wyndham-Fort-Myers-Central.h23367.Hotel-Information) ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "Clean room, lots of kids activities. " [](https://expedia.co.uk/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Hyatt Place Fort Myers/at The Forum](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/3f55519b_y.jpg) ### Hyatt Place Fort Myers/at The Forum 10/10 Excellent "Yes very clean " [](https://expedia.co.uk/Fort-Myers-Hotels-Hyatt-Place-Fort-Myersat-The-Forum.h2847745.Hotel-Information) ![Hilton Garden Inn Ft Myers](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/d8bd559a_y.jpg) ### Hilton Garden Inn Ft Myers 10/10 Excellent "Was just a comfortable hotel conveniently located for the things we wanted to do when passing through Ft. Myers. Hotel was comfortably appointed… staff was friendly… and the food at the restaurant was surprisingly good. I really liked the breakfast buffet." [](https://expedia.co.uk/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) ![DiamondHead Beach Resort](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "Great room and facilities. Loved the location!!" [](https://expedia.co.uk/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Matlacha Isles hotel booking with Expedia? ### How much is the nightly rate at a Matlacha Isles hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in Florida Gulf Coast ](https://www.expedia.co.uk/5Star-Florida-Gulf-Coast-Hotels.s50-0-d553248635974622901.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Pine Island ](https://www.expedia.co.uk/5Star-Pine-Island-Hotels.s50-0-d553248635083900600.Travel-Guide-Filter-Hotels) - [Alden Pines Hotels ](https://www.expedia.co.uk/Alden-Pines-Hotels.d553248635976474573.Travel-Guide-Hotels) - [Bokeelia Hotels ](https://www.expedia.co.uk/Bokeelia-Hotels.d6177515.Travel-Guide-Hotels) - [Gay-Friendly Hotels in Burnt Store ](https://www.expedia.co.uk/Burnt-Store-Cape-Coral-Hotels-Gay-Friendly-Hotel.0-n553248635976481229-0-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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