Title: The Best Hotels in Matlacha Isles, Cape Coral - 2025 Updated Prices | Expedia.co.uk [Holiday Rentals in Cape Coral](https://expedia.co.uk/Cape-Coral-Holiday-Rentals.d6521.Travel-Guide-HolidayRentals)[Flights to Cape Coral](https://expedia.co.uk/Cheap-Flights-To-Cape-Coral.d6521.Travel-Guide-Flights)[Things to do in Cape Coral](https://expedia.co.uk/Things-To-Do-In-Cape-Coral.d6521.Travel-Guide-Activities)[Matlacha Isles Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Matlacha-Isles.d553248635976471942.Car-Hire-Guide)[Matlacha Isles Holidays](https://expedia.co.uk/Matlacha-Isles.d553248635976471942.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels in Matlacha Isles, Cape Coral - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Matlacha Isles Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&lodging=APART_HOTEL) Resort [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&lodging=HOTEL_RESORT) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&lodging=APARTMENT) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&amenities=POOL) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&amenities=OCEAN_VIEW) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&amenities=HOT_TUB) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&travelerType=family_friendly) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&lodging=COTTAGE) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&lodging=CONDO) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&amenities=PETS) Villa [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&lodging=VILLA) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Matlacha+Isles%2C+Cape+Coral%2C+Florida%2C+United+States+of+America®ionId=553248635976471942&latLong=26.640328%2C-82.05037&adults=2&startDate=2025-12-04&d1=2025-12-04&endDate=2025-12-06&d2=2025-12-06&amenities=WATER_PARK) ## Check prices for these dates Tonight [20 Nov - 21 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976471942&startDate=2025-11-20&endDate=2025-11-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [21 Nov - 22 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976471942&startDate=2025-11-21&endDate=2025-11-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [21 Nov - 23 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976471942&startDate=2025-11-21&endDate=2025-11-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976471942&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Top Trending Hotels Near Matlacha Isles, Cape Coral ![On the beach, white sand, kayaking, motor boating](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/89736118.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/39279b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, 3 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/17d9d33f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Sanibel Harbour Resort & Spa 10.7 mi from Matlacha Isles 8.4/10 Very good (1008) "This was thr best place that we have ever stayed at. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew £189 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/0be36f55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/98f0aac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/693ea816.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/430000/421600/421546/a638e8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Allure Suites 10.5 mi from Matlacha Isles 7.6/10 Good (1006) "Was clean staff was very nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard J [](https://www.expedia.co.uk/Fort-Myers-Hotels-Allure-Suites.h421546.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/w2868h1920x12y0-118022ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking (Upgrade) | Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/3b030475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/d7c7e7e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109300000/109299300/109299203/54b129e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Fort Myers East I-75 15.4 mi from Matlacha Isles 9.6/10 Exceptional (331) "Friendly staff, great breakfast, clean room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shellie £79 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Comfort-Suites.h109299203.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/cebf36b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking, Microwave | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/55b8bfc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/42212932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/20000/17200/17131/d9380a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Fort Myers Inn & Suites 12.9 mi from Matlacha Isles 8.8/10 Excellent (1079) "Service was great, cleanliness was good ad well, really enjoyed breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina £62 includes taxes & fees 26 Nov - 27 Nov [](https://www.expedia.co.uk/Fort-Myers-Hotels-Best-Western-Fort-Myers-Inn-Suites.h17131.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/16c0566c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/039cd0a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/a4826c5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/800000/798500/798422/1fa522a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park 17.4 mi from Matlacha Isles 8.0/10 Very good (1484) "Clean, comfortable and quiet facility… I would stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £56 includes taxes & fees 26 Nov - 27 Nov [](https://www.expedia.co.uk/Fort-Myers-Hotels-Days-Inn-Suites-By-Wyndham-Fort-Myers-Near-JetBlue-Park.h798422.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/83cb6bb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/2c14a98f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/432e75cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2630000/2625800/2625745/e00a9bae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Fort Myers Sanibel 11.3 mi from Matlacha Isles 8.6/10 Excellent (1003) "Clean room, wonderful staff, and nice breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Danielle £81 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Residence-Inn-By-Marriott-Fort-Myers-Sanibel.h2625745.Hotel-Information) ![Laptop workspace, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114950000/114942200/114942118/cf5bc44c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-sized fridge, microwave, ice maker](https://images.trvl-media.com/lodging/115000000/114950000/114942200/114942118/6867ea2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114950000/114942200/114942118/53b2f3fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114950000/114942200/114942118/a228a358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### StudioRes Fort Myers Airport 18.4 mi from Matlacha Isles 8.4/10 Very good (8) "Clean room, staff, amenities, easy check in, easy access to gas stations, restaurants, and retail. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gina £76 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Studiores-Fort-Myers.h114942118.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/200000/199300/199215/426c3abd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/200000/199300/199215/153dc338.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports bar](https://images.trvl-media.com/lodging/1000000/200000/199300/199215/bc3089c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/200000/199300/199215/3c327749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Fort Myers Springs Resort 17.4 mi from Matlacha Isles 6.0/10 (1000) "It was a really clean hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina £54 includes taxes & fees 26 Nov - 27 Nov [](https://www.expedia.co.uk/Fort-Myers-Hotels-Days-Inn-By-Wyndham-Fort-Myers-Springs-Resort.h199215.Hotel-Information) ![Hypo-allergenic bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/1000000/30000/22200/22106/cd5e3916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22200/22106/93a4fef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, down duvets, individually decorated](https://images.trvl-media.com/lodging/1000000/30000/22200/22106/f2cb8ccd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/1000000/30000/22200/22106/e7cf9881.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Fort Myers North Hancock, 10.3 mi from Matlacha Isles 5.6/10 (296) "Friendly staff great location close to beaches for a reasonable price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £49 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Fort-Myers-Hotels-Econo-Lodge-North.h22106.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50500/50468/ce27f724.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/60000/50500/50468/a4ca1a35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/60000/50500/50468/54a3a4b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/60000/50500/50468/ffc7e96f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Fort Myers Waterfront Hancock, 10.3 mi from Matlacha Isles 7.4/10 Good (1005) "Great hospitality. Perfect view on the water. Great restaurant on site and IHOP next door. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol £86 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Fort-Myers-Hotels-Best-Western-Fort-Myers-Waterfront.h50468.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1790000/1781300/1781240/e95f6f02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/2000000/1790000/1781300/1781240/98925cbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/2000000/1790000/1781300/1781240/a047fbf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1790000/1781300/1781240/41858a2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Ft Myers I-75 by IHG 15.6 mi from Matlacha Isles 8.0/10 Very good (741) "The suite is equipped with everything you need." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabet £58 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Candlewood-Suites-Ft-Myers-I75.h1781240.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916874/d99aa2c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916874/w5749h3840x5y0-525deb5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916874/w5762h3835x5y5-9feeae4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916874/w5757h3835x0y5-6dc8e67a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Banyan Hotel Fort Myers, Tapestry Collection by Hilton 11.1 mi from Matlacha Isles 8.6/10 Excellent (832) "Staff was friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £125 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-The-Banyan-Hotel-Fort-Myers.h1916874.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/1000000/20000/14300/14287/d5700973.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/14300/14287/d101c196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard view](https://images.trvl-media.com/lodging/1000000/20000/14300/14287/f398452b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14300/14287/c7d9c596.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Travelodge by Wyndham Fort Myers North Hancock, 10.2 mi from Matlacha Isles 5.8/10 (1001) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Blaine £41 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Fort-Myers-Hotels-Travelodge-By-Wyndham-Fort-Myers-North.h14287.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/30000/22400/22386/d60a7543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22400/22386/a939713b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast and dinner](https://images.trvl-media.com/lodging/1000000/30000/22400/22386/68348101.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/22400/22386/a6afb300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Fort Myers Cape Coral 12.7 mi from Matlacha Isles 8.2/10 Very good (1003) "Was a terrific stay and they went out of their way to accommodate my injured dog even giving us a late checkout " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) laura £68 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Courtyard-By-Marriott-Fort-Myers-Cape-Coral.h22386.Hotel-Information) ![Deluxe Studio, 1 King Bed, Marina View | View from room](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/bde78c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, Kitchen, Pool View | Living area | TV](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/e75bb4c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/w1995h1500x652y0-ac9ecb97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bicycling](https://images.trvl-media.com/lodging/17000000/16660000/16651900/16651890/e693cbff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Latitude 26 Waterfront Boutique Resort - Fort Myers Beach 12.7 mi from Matlacha Isles 8.8/10 Excellent (1003) "Great Place to Stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JUDY [](https://www.expedia.co.uk/Fort-Myers-Hotels-Latitude-26-Waterfront-Boutique-Resort-Fort-Myers-Beach.h16651890.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1670000/1662000/1661939/c6ebb5bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast on weekdays ](https://images.trvl-media.com/lodging/2000000/1670000/1662000/1661939/254fe894.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1670000/1662000/1661939/cf31ca74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1670000/1662000/1661939/fe9fab00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Fort Myers - Colonial Blvd 13 mi from Matlacha Isles 9.4/10 Exceptional (1001) "Clean room, friendly staff, nice breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mercedes £96 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-Hampton-Inn-Suites-Fort-Myers-Colonial-Blvd.h1661939.Hotel-Information) ![Standard Room, 2 Queen Beds | Premium bedding, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/19000000/18120000/18111200/18111123/5232bbaf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Single Room, 1 King Bed | Premium bedding, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/19000000/18120000/18111200/18111123/4c7e1b1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/19000000/18120000/18111200/18111123/9c590979.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, River View | Premium bedding, desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/19000000/18120000/18111200/18111123/1723efbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riverview Inn Hancock, 10.4 mi from Matlacha Isles 7.6/10 Good (608) "A nice and quiet place to stay for the weekend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn £51 includes taxes & fees 26 Nov - 27 Nov [](https://www.expedia.co.uk/Fort-Myers-Hotels-Riverview-Inn.h18111123.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/3f55519b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/504bf71e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/0fdbdc99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2850000/2847800/2847745/90cc54bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Fort Myers/at The Forum 15.4 mi from Matlacha Isles 8.2/10 Very good (1008) "Goodlocation" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Michael £79 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Fort-Myers-Hotels-Hyatt-Place-Fort-Myersat-The-Forum.h2847745.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/b06bf9be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/w3000h1997x0y3-c76bf6b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/8f32b7a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11200/11134/4ec8c9b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway 11.4 mi from Matlacha Isles 8.0/10 Very good (1004) "Great place to stay and breakfast was delicious " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Keishly £79 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Fort-Myers-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Ft-Myers-Sanibel-Gateway.h11134.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1560000/1551400/1551348/9b4d626a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1560000/1551400/1551348/1f7729f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/2000000/1560000/1551400/1551348/851990d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1560000/1551400/1551348/2a531aa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn and Suites Fort Myers I-75 16.8 mi from Matlacha Isles 6.6/10 (1005) "This place is the roach motel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ENRIQUE £57 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Fort-Myers-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Fort-Myers-Airport.h1551348.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-05&endDate=2025-12-06®ionId=553248635976471942&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Where to stay in Matlacha Isles Find the best Matlacha Isles areas for the activities you enjoy most. - Pelican - Caloosahatchee - Mariner - Hancock - Yacht Club ![](https://mediaim.expedia.com/destination/9/350251ac0d9ccc7ca1cb30ed3f0f1512.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/6787174d3f020d364df18c0504ee6a50.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/0db9ea0d958f3eddc014a2724a550e04.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/f6aa46e3ec22aaa67f528102c099f4db.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/9/0383eed5f73bce5b51600c8b78edb8e2.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976481346) ![Pelican map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:oacaDfs%7BsNq_C_z%40an%40al%40m%7B%40sH%7Bo%40dPrGsaGz%40%7DqClLse%40%7C%40se%40fdIbAdSjDhvAeAhg%40t%60B%7CX%7EmEvDdeCswCxcBa%7CAha%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=E70lew0W6sFXzCxHzRLVFKaS8Mg=) ### Pelican While visiting Pelican, you might make a stop by sights like Tarpon Point and Harbour View Gallery. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976481346) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496945-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496204-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496304-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496233-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496139-cape-coral.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635975748682) ![Caloosahatchee map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:_l_aDbxisNce%40ImL%7DEg%60Ah%40uvGX%7D%40oaKhPcAlh%40%60nAnc%40dLxl%40qG%7Es%40b%5Bl%5EiGpl%40%60%5D%60PgJnPzZfJvc%40lj%40%7ETx%7E%40vFyBra%40sMlMiPd%60ApPlx%40oFjD&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=Cya_maxw6zlgfysES9DHBgO1unY=) ### Caloosahatchee If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748682) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976470523) ![Mariner map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:etqaDpkssN_oMcA%3FalFkd%40kmAhe%40%3FNgd%40viGlBxHzCfg%40%3Fr%5EgQ%7EeAx%7DClc%40n_BrG%60k%40%7D%40j%60A&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=4CJoAD0sRorEN_B-6JMiJBcI87w=) ### Mariner While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976470523) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/495000/495865-south-florida.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496727-north-fort-myers.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/496000/496600-north-fort-myers.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/26729640c04cf35e3216cbbc607fc1c6.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) ![](https://mediaim.expedia.com/destination/1/2774ef6de242fcb260ae5796be4d6871.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976420438) ![Hancock map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:oyraDxtmsN_qFusOp%40mwEi%40gBjy%40oaAvI%7EKm%40tPbe%40%60f%40fj%40uGYdI%7BPfH_BnOvJ%7CHxNmH%7ERe%40jBrDyWjUxHzu%40xNlGv%5D%7EBrIfHv_%40lx%40v%5BfLx%60%40bd%40xQhH%60FhIbn%40wGb%5Dm%40hCmGph%40cL%7CCvyF%60%40%7CsFgqA%3FaN%7EAax%40CcNj%40%7B_%40rHuYvK&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=iSHUTH5d48PG0kePXw5a0CSgbnA=) ### Hancock While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976420438) [](https://www.expedia.co.uk/Hotel-Search?pwaOverlay=map®ionId=553248635976659287) ![Yacht Club map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:wo%60aDlwisN%7DGeBsb%40s%5BwJe%5EwIeNzKeXJaI%60HqMH%7D_%40oS%40BuVjEEAwCtLNhCcKhHzDlPbEhOzGxKlC%7EG%7B%40hb%40xAWhKeL%7EViP%60w%40cAdo%40nKvXq%40hFgd%40f%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=9v6IXRj89bAFRtqo7x5Ob4JRxkI=) ### Yacht Club While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby. [See properties](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976659287) ## Top Matlacha Isles Hotel Reviews ![Lani Kai Beachfront Resort](https://images.trvl-media.com/lodging/1000000/440000/438800/438796/b5b17142_y.jpg) ### Lani Kai Beachfront Resort 10/10 Excellent "Overall an excellent stay. Minor issue with the parking lot attendant. They recommended to only turn the A/C down to 72. That is quite warm for me to sleep in. Now the good- The view is amazing. Right on the ocean/beach. So many excellent places to eat nearby. We rented a car but we walked everywhere. Staff were courteous and helpful. Great music played from 9-9. Not to loud. It was exactly what we were looking for, hope to return soon." [](https://expedia.co.uk/Fort-Myers-Hotels-Lani-Kai-Beachfront-Resort.h438796.Hotel-Information) ![Pink Shell Beach Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/15700/15603/5f038ed2_y.jpg) ### Pink Shell Beach Resort and Marina 10/10 Excellent "Great resort. Free breakfast is outstanding. Room was clean and spacious. Free bikes and beach chairs. I would highly recommend. " [](https://expedia.co.uk/Fort-Myers-Hotels-Pink-Shell-Beach-Resort-And-Marina.h15603.Hotel-Information) ![Holiday Inn Express Cape Coral-Fort Myers Area by IHG](https://images.trvl-media.com/lodging/1000000/30000/26900/26860/ab39b98c_y.jpg) ### Holiday Inn Express Cape Coral-Fort Myers Area by IHG 10/10 Excellent "Room was very clean, the staff were outstanding " [](https://expedia.co.uk/Fort-Myers-Hotels-Holiday-Inn-Express-Cape-Coral-Fort-Myers-Area.h26860.Hotel-Information) ![DiamondHead Beach Resort](https://images.trvl-media.com/lodging/1000000/210000/200700/200632/814c4388_y.jpg) ### DiamondHead Beach Resort 10/10 Excellent "Very clean, super nice staff and the room was more than we expected." [](https://expedia.co.uk/Fort-Myers-Hotels-DiamondHead-Beach-Resort.h200632.Hotel-Information) ![Sanibel Island Beach Resort](https://images.trvl-media.com/lodging/18000000/17300000/17298900/17298818/w2247h1500x326y0-2ea06bb5_y.jpg) ### Sanibel Island Beach Resort 10/10 Excellent "The room was very clean, great updated bathroom comfortable beds. Great restaurant onsite, beautiful beach. " [](https://expedia.co.uk/Fort-Myers-Hotels-Sanibel-Island-Beach-Resort.h17298818.Hotel-Information) ![Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral](https://images.trvl-media.com/lodging/1000000/130000/129300/129295/81b75b6a_y.jpg) ### Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral 10/10 Excellent "The hotel was affordable, clean, safe, and had everything I needed for my 2 night stay. Continental breakfast was a nice touch, as well as the ice water and cookies in the front lobby. The staff was also polite and friendly. Will stay again! " [](https://expedia.co.uk/Fort-Myers-Hotels-Fairfield-Inn-Suites-By-Marriott-Ft-MyersCape-Coral.h129295.Hotel-Information) ![The Lighthouse Resort Inn & Suites](https://images.trvl-media.com/lodging/1000000/810000/800800/800715/w2800h1779x0y3-dbc2bfa3_y.jpg) ### The Lighthouse Resort Inn & Suites 10/10 Excellent "Room was clean but in the older section. Looking forward to a remodel or allowing pets into the new part. Love staying at the Lighthouse and visit regularly " [](https://expedia.co.uk/Fort-Myers-Hotels-The-Lighthouse-Resort-Inn-Suites.h800715.Hotel-Information) ![Marriott Sanibel Harbour Resort & Spa](https://images.trvl-media.com/lodging/1000000/10000/3100/3079/ac9a3a07_y.jpg) ### Marriott Sanibel Harbour Resort & Spa 10/10 Excellent "Staff was very friendly. Nelson went out of the way to help me" [](https://expedia.co.uk/Fort-Myers-Hotels-Marriott-Sanibel-Harbour-Resort-Spa.h3079.Hotel-Information) ![Hilton Garden Inn Ft Myers](https://images.trvl-media.com/lodging/1000000/850000/848800/848740/d8bd559a_y.jpg) ### Hilton Garden Inn Ft Myers 10/10 Excellent "Clean room, great front desk staff, good breakfast offerings. We would definately stay there again!" [](https://expedia.co.uk/Fort-Myers-Hotels-Hilton-Garden-Inn-Ft-Myers.h848740.Hotel-Information) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Matlacha Isles. ### How can I save on a Matlacha Isles hotel booking with Expedia? > With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Matlacha Isles hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings. ### How much is the nightly rate at a Matlacha Isles hotel? > Hotel prices in Matlacha Isles often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. 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