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Our top choices for Matlacha Isles hotels

Holiday Inn Express & Suites Fort Myers Airport by IHG
Holiday Inn Express & Suites Fort Myers Airport by IHG18 mi from Matlacha Isles
9.6 out of 10, Exceptional, (1,020 reviews)
The price is £157
includes taxes & fees
22 Mar - 23 Mar

Hampton Inn Fort Myers-Airport & I-75
Hampton Inn Fort Myers-Airport & I-7516.6 mi from Matlacha Isles
9.0 out of 10, Wonderful, (1,002 reviews)
The price is £98
includes taxes & fees
6 Apr - 7 Apr

Pink Shell Beach Resort and Marina
Pink Shell Beach Resort and Marina13.5 mi from Matlacha Isles
9.4 out of 10, Exceptional, (1,285 reviews)
The price is £535
includes taxes & fees
26 Mar - 27 Mar

Home2 Suites by Hilton Fort Myers Airport
Home2 Suites by Hilton Fort Myers Airport18.7 mi from Matlacha Isles
9.0 out of 10, Wonderful, (454 reviews)
The price is £122
includes taxes & fees
5 Apr - 6 Apr

Tween Waters Island Resort & Spa
Tween Waters Island Resort & Spa12.5 mi from Matlacha Isles
8.6 out of 10, Excellent, (1,006 reviews)
The price is £373
includes taxes & fees
4 Apr - 5 Apr

Lani Kai Beachfront Resort
Lani Kai Beachfront Resort14.4 mi from Matlacha Isles
9.0 out of 10, Wonderful, (1,293 reviews)
The price is £223
includes taxes & fees
5 Apr - 6 Apr

SpringHill Suites by Marriott Fort Myers Airport
SpringHill Suites by Marriott Fort Myers Airport16.8 mi from Matlacha Isles
8.6 out of 10, Excellent, (1,006 reviews)
The price is £107
includes taxes & fees
5 Apr - 6 Apr

Marriott Sanibel Harbour Resort & Spa
Marriott Sanibel Harbour Resort & Spa10.7 mi from Matlacha Isles
8.4 out of 10, Very good, (1,011 reviews)
The price is £316
includes taxes & fees
6 Apr - 7 Apr

Comfort Inn Fort Myers Northeast
Comfort Inn Fort Myers Northeast16 mi from Matlacha Isles
7.8 out of 10, Good, (696 reviews)
The price is £75
includes taxes & fees
5 Apr - 6 Apr

Sanibel Island Beach Resort
Sanibel Island Beach Resort14.1 mi from Matlacha Isles
9.2 out of 10, Wonderful, (1,665 reviews)
The price is £374
includes taxes & fees
5 Apr - 6 Apr

Holiday Inn Express & Suites Punta Gorda by IHG
Holiday Inn Express & Suites Punta Gorda by IHG17.9 mi from Matlacha Isles
9.4 out of 10, Exceptional, (1,006 reviews)
The price is £116
includes taxes & fees
5 Apr - 6 Apr

Sanibel Inn
Sanibel Inn13.9 mi from Matlacha Isles
9.0 out of 10, Wonderful, (1,013 reviews)
The price is £486
includes taxes & fees
6 Apr - 7 Apr

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park17.4 mi from Matlacha Isles
8.0 out of 10, Very good, (1,625 reviews)
The price is £82
includes taxes & fees
29 Mar - 30 Mar

Baymont by Wyndham Punta Gorda/Port Charlotte
Baymont by Wyndham Punta Gorda/Port Charlotte18 mi from Matlacha Isles
8.4 out of 10, Very good, (1,202 reviews)
The price is £92
includes taxes & fees
7 Apr - 8 Apr

DiamondHead Beach Resort
DiamondHead Beach Resort14.6 mi from Matlacha Isles
9.2 out of 10, Wonderful, (1,078 reviews)
The price is £375
includes taxes & fees
5 Apr - 6 Apr

MainStay Suites Fort Myers East I-75
MainStay Suites Fort Myers East I-7515.4 mi from Matlacha Isles
9.6 out of 10, Exceptional, (309 reviews)
The price is £138
includes taxes & fees
7 Apr - 8 Apr

Quality Inn Fort Myers Cape Coral
Quality Inn Fort Myers Cape Coral11.4 mi from Matlacha Isles
7.4 out of 10, Good, (238 reviews)
The price is £79
includes taxes & fees
5 Apr - 6 Apr

Sundial Beach Resort & Spa
Sundial Beach Resort & Spa14.4 mi from Matlacha Isles
8.6 out of 10, Excellent, (2,604 reviews)
The price is £440
includes taxes & fees
22 Mar - 23 Mar

Comfort Inn & Suites Fort Myers Airport
Comfort Inn & Suites Fort Myers Airport17.3 mi from Matlacha Isles
8.8 out of 10, Excellent, (1,147 reviews)
The price is £82
includes taxes & fees
5 Apr - 6 Apr

Hyatt Place Fort Myers/at The Forum
Hyatt Place Fort Myers/at The Forum15.4 mi from Matlacha Isles
8.2 out of 10, Very good, (1,011 reviews)
The price is £157
includes taxes & fees
29 Mar - 30 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.

Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Cape Coral Farmers Market are some notable places to visit nearby.

Hancock
While visiting Hancock, you might make a stop by sights like Lee Island and Four Mile Cove Ecological Preserve.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
Top Matlacha Isles Hotel Reviews

Baymont by Wyndham Fort Myers Central
4/10 Poor
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