What is Matlacha Isles like?

Travellers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighbourhood.

How many hotels will I be able to find in the Matlacha Isles area?

When you want to put your feet up after a day of exploring the sights in Cape Coral, you can choose from 17 Expedia hotels and other accommodation options in Matlacha Isles.

If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?

Yes, the majority of room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals in Matlacha Isles.

What are the top things to see and do in Matlacha Isles?

A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens and Cape Royal Golf Club. While you're out sightseeing in Cape Coral, make sure that you visit other sights such as Little Dead Key or Big Dead Key.

The Best Hotels in Matlacha Isles, Cape Coral - 2026 Updated Prices

An aerial view of a coastal town with a marina, surrounded by water and green land.

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Our top choices for Matlacha Isles hotels

1. Matlacha on Shoreview

0.9 mi from Matlacha Isles

Robby

includes taxes & fees

11 Sept - 12 Sept

2. Matlacha Tiny Village

1.6 mi from Matlacha Isles

Lori

includes taxes & fees

13 Sept - 14 Sept

3. Angler's Inn

1.6 mi from Matlacha Isles

Paul

includes taxes & fees

11 Sept - 12 Sept

4. Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Hancock, 7.2 mi from Matlacha Isles

Glamaris

includes taxes & fees

16 Sept - 17 Sept

5. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Caloosahatchee, 7.6 mi from Matlacha Isles

Taylor

includes taxes & fees

20 Sept - 21 Sept

6. Residence Inn by Marriott Fort Myers Sanibel

11.3 mi from Matlacha Isles

Laura

includes taxes & fees

13 Sept - 14 Sept

7. OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

Caloosahatchee, 7.7 mi from Matlacha Isles

Sarah

includes taxes & fees

21 Sept - 22 Sept

8. HomeTowne Studios by Red Roof Fort Myers

13.5 mi from Matlacha Isles

Mj

includes taxes & fees

14 Sept - 15 Sept

In-room safe, desk, laptop workspace, blackout curtains

9. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Downtown Cape Coral, 8.5 mi from Matlacha Isles

Tom

includes taxes & fees

4 Oct - 5 Oct

Desk, iron/ironing board, free WiFi, bed sheets

10. Best Western Fort Myers Waterfront

Hancock, 10.3 mi from Matlacha Isles

Danielle

includes taxes & fees

14 Sept - 15 Sept

Suite, 2 Bedrooms, Marina View | Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe

11. The Westin Cape Coral Resort At Marina Village

Pelican, 7.7 mi from Matlacha Isles

includes taxes & fees

28 Sept - 29 Sept

12. Allure Suites

10.5 mi from Matlacha Isles

Danny

includes taxes & fees

11 Sept - 12 Sept

13. Dolphin Key Resort

Caloosahatchee, 8.5 mi from Matlacha Isles

james

includes taxes & fees

5 Oct - 6 Oct

14. Hampton Inn Fort Myers Downtown

10.9 mi from Matlacha Isles

Craig

includes taxes & fees

17 Sept - 18 Sept

15. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

12.3 mi from Matlacha Isles

Jason

includes taxes & fees

16 Sept - 17 Sept

16. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

11.4 mi from Matlacha Isles

Sidney

includes taxes & fees

16 Sept - 17 Sept

1 King Bed Suite w/ Efficiency Non Smoking | Premium bedding, down duvets, desk, laptop workspace

17. Quality Inn Fort Myers Cape Coral

11.4 mi from Matlacha Isles

Christopher

includes taxes & fees

5 Oct - 6 Oct

Premium bedding, down duvets, desk, laptop workspace

18. Candlewood Suites Fort Myers Sanibel Gateway by IHG

12.9 mi from Matlacha Isles

John

includes taxes & fees

13 Sept - 14 Sept

19. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

12.4 mi from Matlacha Isles

Kenton Sean

includes taxes & fees

14 Sept - 15 Sept

20. Best Western Fort Myers Inn & Suites

12.9 mi from Matlacha Isles

William

includes taxes & fees

13 Sept - 14 Sept

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Where to stay in Matlacha Isles

Find the best Matlacha Isles areas for the activities you enjoy most.

A pier extending into the water with two gazebos at the end, under a sunset sky.

Pelican

While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

See properties

A coastal residential area with a marina, dense greenery, and high-rise buildings in the background.

Caloosahatchee

If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

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A coastal cityscape with a beach, marina, and dense urban area.

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.

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A sunset over a calm lake with a dock and palm trees.

Yacht Club

While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.

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A wooden pier extending into calm water with a clear sky and distant land.

Burnt Store

When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.

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Top Matlacha Isles Hotel Reviews

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

8/10 Good

"."

Sanibel Island Beach Resort

8/10 Good

"The room was amazing and very clean. They did give us the wrong room. Stated we were getting one of the last rooms. Then when we got there we were one of maybe 15 people there. The night we arrived the boy in the office wasn’t very helpful and had a bit of a chip on his shoulder. But we overheard he was fired the morning we left. Every other staff member was fabulous. They were so helpful and friendly. The lady at the pool bar is one in a million. We had no complaints. Would have liked to relax in a hot tub after walking the beach all day so I guess that’s a suggestion lol. Maybe spray the property for the biting gnats? All in all great stay, great location, great people as well."

Search Hotels in Matlacha Isles, Cape Coral

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Treat yourself

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Check prices for these dates

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Our top choices for Matlacha Isles hotels

1. Matlacha on Shoreview

2. Matlacha Tiny Village

3. Angler's Inn

4. Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

5. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

6. Residence Inn by Marriott Fort Myers Sanibel

7. OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

8. HomeTowne Studios by Red Roof Fort Myers

9. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

10. Best Western Fort Myers Waterfront

11. The Westin Cape Coral Resort At Marina Village

12. Allure Suites

13. Dolphin Key Resort

14. Hampton Inn Fort Myers Downtown

15. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

16. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

17. Quality Inn Fort Myers Cape Coral

18. Candlewood Suites Fort Myers Sanibel Gateway by IHG

19. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

20. Best Western Fort Myers Inn & Suites

Where to stay in Matlacha Isles

Pelican

Caloosahatchee

Hancock

Yacht Club

Burnt Store

Top Matlacha Isles Hotel Reviews

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

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