Search Hotels in Matlacha Isles, Cape Coral
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Matlacha Isles hotels
Lani Kai Beachfront Resort
Lani Kai Beachfront Resort14.4 mi from Matlacha Isles
9.0 out of 10, Wonderful, (1,423 reviews)
"Wonderful vacation spot for couples or family. "
Scott
The price is £148
includes taxes & fees
20 May - 21 May
MainStay Suites Fort Myers East I-75
MainStay Suites Fort Myers East I-7515.4 mi from Matlacha Isles
9.6 out of 10, Exceptional, (350 reviews)
"Great stay, clean rooms, clean common area. "
Oscar
The price is £89
includes taxes & fees
30 Apr - 1 May
The Bay Inn at Lani Kai
The Bay Inn at Lani Kai14.4 mi from Matlacha Isles
7.6 out of 10, Good, (391 reviews)
"Excellent. We just enjoy so much !!Rooms very clean and just across de beach !!"
Marie
The price is £104
includes taxes & fees
26 Apr - 27 Apr
Comfort Suites Fort Myers East I-75
Comfort Suites Fort Myers East I-7515.4 mi from Matlacha Isles
9.6 out of 10, Exceptional, (449 reviews)
"Loved my stay here, will be back soon and will book my room here. Breakfast options were nice and staff were very friendly!
"
Richard
The price is £78
includes taxes & fees
10 May - 11 May
Pointe Estero Beach Resort
Pointe Estero Beach Resort17.8 mi from Matlacha Isles
9.2 out of 10, Wonderful, (1,001 reviews)
"Love this place!!"
Teneille
The price is £351
includes taxes & fees
18 May - 19 May
Park Motel
Park MotelDiplomat, 10.7 mi from Matlacha Isles
9.2 out of 10, Wonderful, (46 reviews)
"Clean, quiet, very friendly and helpful staff, hot tub in room very relaxing."
Kristeen
The price is £73
includes taxes & fees
30 Apr - 1 May
StudioRes by Marriott Fort Myers Airport
StudioRes by Marriott Fort Myers Airport18.4 mi from Matlacha Isles
9.4 out of 10, Exceptional, (47 reviews)
"Loved stay here!!! "
Melissa
The price is £66
includes taxes & fees
30 Apr - 1 May
Sanibel Island Beach Resort
Sanibel Island Beach Resort14.1 mi from Matlacha Isles
9.2 out of 10, Wonderful, (1,812 reviews)
"Great restaurant and beach bar on premises. "
Bruce
The price is £192
includes taxes & fees
17 May - 18 May
Pink Shell Beach Resort and Marina
Pink Shell Beach Resort and Marina13.5 mi from Matlacha Isles
9.4 out of 10, Exceptional, (1,327 reviews)
"Great spot can’t wait to come back! "
DANE
The price is £281
includes taxes & fees
25 May - 26 May
Boca Grande Hotel
Boca Grande Hotel17.9 mi from Matlacha Isles
8.8 out of 10, Excellent, (626 reviews)
"The rooms were dated and the amenities limited, but the staff was wonderful and all of the beaches and restaurants of Boca Grande were nearby!"
John
The price is £129
includes taxes & fees
26 Apr - 27 Apr
MALU LANI Inn & Marina
MALU LANI Inn & Marina7.8 mi from Matlacha Isles
10.0 out of 10, Exceptional, (5 reviews)
"Beautiful property, peaceful, clean rental. Super responsive owner and all the things you need. Perfect location for boaters. Loved this stay and would definitely rent again! "
April
The price is £301
includes taxes & fees
30 Apr - 1 May
Holiday Inn Express & Suites Fort Myers Airport by IHG
Holiday Inn Express & Suites Fort Myers Airport by IHG18 mi from Matlacha Isles
9.6 out of 10, Exceptional, (1,000 reviews)
"Great place to stay a few nights "
Antonino
The price is £85
includes taxes & fees
29 Apr - 30 Apr
The Anchor Inn
The Anchor Inn13.5 mi from Matlacha Isles
10.0 out of 10, Exceptional, (26 reviews)
"The property was beautiful, everything was in perfect condition, would definitely go back!!"
Jennifer
The price is £224
includes taxes & fees
11 May - 12 May
Comfort Inn Fort Myers Northeast
Comfort Inn Fort Myers Northeast16 mi from Matlacha Isles
7.8 out of 10, Good, (719 reviews)
"Friendly staff!"
Tom
The price is £62
includes taxes & fees
11 May - 12 May
Latitude 26 Waterfront Resort & Marina
Latitude 26 Waterfront Resort & Marina12.6 mi from Matlacha Isles
8.6 out of 10, Excellent, (1,000 reviews)
"Place is quiet and right down the street from the beach"
Bryan
The price is £84
includes taxes & fees
27 Apr - 28 Apr
Americas Best Value Inn Ft. Myers
Americas Best Value Inn Ft. Myers12 mi from Matlacha Isles
7.6 out of 10, Good, (1,232 reviews)
"Great staff loved the quick breakfast!"
Emil Peter Busko
The price is £46
includes taxes & fees
30 Apr - 1 May
Flamingo Inn
Flamingo Inn17.4 mi from Matlacha Isles
7.8 out of 10, Good, (1,003 reviews)
"Place was clean and close to beach . Host was very nice "
Kitra
The price is £142
includes taxes & fees
17 May - 18 May
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach12.7 mi from Matlacha Isles
8.8 out of 10, Excellent, (1,003 reviews)
"Amazing place to stay! "
Kristen
The price is £85
includes taxes & fees
27 Apr - 28 Apr
Extended Stay America Premier Suites - Fort Myers - Airport
Extended Stay America Premier Suites - Fort Myers - Airport14.7 mi from Matlacha Isles
8.8 out of 10, Excellent, (951 reviews)
"Great stay"
Cliff
The price is £53
includes taxes & fees
26 Apr - 27 Apr
Matlacha Tiny Village
Matlacha Tiny Village1.6 mi from Matlacha Isles
8.8 out of 10, Excellent, (286 reviews)
"Super cute place!! Super clean and comfortable."
Francesca
The price is £206
includes taxes & fees
26 Apr - 27 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
Top Matlacha Isles Hotel Reviews
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- 5 Star Hotels in Florida Gulf Coast
- 5 Star Hotels in Pine Island
- Alden Pines Hotels
- Bokeelia Hotels
- Gay-Friendly Hotels in Burnt Store
- Burnt Store Hotels
- Burnt Store Marina Hotels
- Burnt Store Marina Hotels
- Caloosahatchee Hotels
- Resorts in Cape Coral
- Adults Only Resorts & in Cape Coral
- Beach Resorts & in Cape Coral
- Cheap Hotels in Cape Coral
- Golf Hotels in Cape Coral
- Hotels with Parking in Cape Coral
- Hotels with Pool in Cape Coral
- Hotels with smoking rooms in Cape Coral
- Luxury Hotels in Cape Coral
- Shopping Hotels in Cape Coral
- Cape Coral Hotels
- Holiday Homes in Cape Coral
- Villas in Cape Coral
- Cape Harbour Hotels
- Lee County Hotels
- Diplomat Hotels
- Hotels near Dolphin Marina
- Edison Park Historic District Hotels
- Flamingo Bay Hotels
- Serviced Apartments in Florida Gulf Coast
- Apartments in Florida Gulf Coast
- Caravan Parks in Florida Gulf Coast
- Chalets in Florida Gulf Coast
- Resorts in Florida Gulf Coast
- Beach Resorts & in Florida Gulf Coast
- Cheap Hotels in Florida Gulf Coast
- Highgate Independent Hotels in Florida Gulf Coast
- La Quinta Inn & Suites Hotels in Florida Gulf Coast
- Luxury Hotels in Florida Gulf Coast
- Pet-Friendly Hotels in Florida Gulf Coast
- Florida Gulf Coast Hotels
- Inns in Florida Gulf Coast
- Lodges in Florida Gulf Coast
- Motels in Florida Gulf Coast
- Villas in Florida Gulf Coast
- Fort Myers Hotels
- Hancock Hotels
- Iona Hotels
- Lochmoor Waterway Estates Hotels
- Manatee Bay Hotels
- Matlacha Hotels
- Matlacha Isles-Matlacha Shores Hotels
- North Captiva Hotels
- North Fort Myers Hotels
- Pelican Hotels
- Serviced Apartments in Pine Island
- Cabin Rentals in Pine Island
- Caravan Parks in Pine Island
- Pine Island Center Hotels
- Chalets in Pine Island
- Sports Hotels in Pine Island
- Beach Resorts & in Pine Island
- Hotels with Air Conditioning in Pine Island
- Hotels with Pool in Pine Island
- Pine Island Hotels
- Houseboats in Pine Island
- Motels in Pine Island
- Safety Harbor Club Hotels
- Saint James City Hotels
- Shell Point Hotels
- Gay-Friendly Hotels in Trafalgar
- Truckland Hotels
- Avis Rental Cars in Florida Gulf Coast
- Budget Rental Cars in Florida Gulf Coast
- Car hire Cape Coral
- First Car Rental Rental Cars in Florida Gulf Coast
- Midsize Car Hire in Pine Island
- Ok Mobility Rental Cars in Florida Gulf Coast
- Rent A Wreck Rental Cars in Cape Coral
- Right Cars Rental Cars in Pine Island
- Sixt Rental Cars in Florida Gulf Coast
- Sports Car Car Hire in Pine Island