Matlacha Isles Holidays from £1,104

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Your Matlacha Isles Holiday

Take the stress out of organising your next adventure by booking a Matlacha Isles holiday package. Take in the sounds and sights of this wonderful neighbourhood and enjoy what it has to offer. If you'd love to sightsee during your trip to Matlacha Isles, head straight for nearby attractions such as Royal Tee Golf Club. Expedia can help you turn your dream Matlacha Isles holiday into reality, no matter your travel plans or budget.

Price found within the past 48 hours. Click for updated prices.
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

Punta Rassa
£1,104
per person
1 Dec - 6 Dec
found 1 day ago
Return direct flight included
Manchester (MAN) to Fort Myers (RSW)
8.6/10 Excellent! (1,002 reviews)
LaPlaya Beach & Golf Resort - A Noble House Resort

LaPlaya Beach & Golf Resort - A Noble House Resort

Vanderbilt Beach
£6,071
per person
7 Jan - 14 Jan
found 16 hours ago
Return flight included
London (LON) to Fort Myers (RSW)
9/10 Wonderful! (1,003 reviews)
Very helpful staff, great Gulf side room. Undergoing some renovation so only one elevator working but didn’t create too much of a problem. Great location, nice people.

Reviewed on 25 Oct 2026

Marco Beach Ocean Suites

Marco Beach Ocean Suites

South End
£1,143
per person
1 Dec - 6 Dec
found 1 day ago
Return direct flight included
Manchester (MAN) to Fort Myers (RSW)
8.8/10 Excellent! (1,569 reviews)
The Perry Hotel Naples

The Perry Hotel Naples

£4,619
per person
7 Jan - 14 Jan
found 16 hours ago
Return flight included
London (LON) to Fort Myers (RSW)
9.6/10 Exceptional! (1,224 reviews)
Naples Beach Club, A Four Seasons Resort

Naples Beach Club, A Four Seasons Resort

Coquina Sands
£8,000
per person
7 Jan - 14 Jan
found 16 hours ago
Return flight included
London (LON) to Fort Myers (RSW)
9.6/10 Exceptional! (41 reviews)
The only downside was the pool was cold and wish they heated it since there was more of a coldfront here this week.

Reviewed on 21 Oct 2026

Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles
A pier extending into the water with two gazebos at the end, under a sunset sky.

Pelican

1 out of top 10 points of interest in this area

While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

A coastal residential area with a marina, dense greenery, and high-rise buildings in the background.

Caloosahatchee

3 out of top 10 points of interest in this area

If you're spending some time in Caloosahatchee, Dolphin Marina and Cape Coral Yacht Club Beach are top sights worth seeing.

A beach with a sunset, a colorful umbrella, and a surfboard.

Hancock

2 out of top 10 points of interest in this area

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.

A waterfront with colorful houses and a dock.

Yacht Club

While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.

A wooden pier extending into calm water with a clear sky and distant land.

Burnt Store

1 out of top 10 points of interest in this area

When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.

Top hotels in Matlacha Isles

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

17260 Harbour Pointe Dr Fort Myers FL
Fully refundableReserve now, pay when you stay
£199
9 Nov - 10 Nov
includes taxes & fees
Marriott Sanibel Harbour Resort & Spa
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

251 Crescent Street Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
£179
1 Nov - 2 Nov
includes taxes & fees
Margaritaville Beach Resort Fort Myers
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

1051 5th St Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
£112
27 Oct - 28 Oct
includes taxes & fees
8.6/10 Excellent! (1,838 reviews)
"Clean, big rooms. Walking distance to the beach, stores, restaurants, bars, ice cream! Walmart is 6-7 minutes down the road which is helpful with kids."

Reviewed on 26 Oct 2026

The Lighthouse Resort Inn & Suites
See all 14,842 properties in Matlacha Isles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Matlacha Isles travel package cost?
The cheapest Matlacha Isles package is £1,104, so the trip of your dreams can become a reality — without breaking the bank. Bundle flights, hotels, car rentals and more to customize a package that suits your travel style.
If I'm not able to travel, can I cancel my Matlacha Isles travel package?
We totally understand that life doesn't always go according to plan. If you've locked in a Matlacha Isles travel package and need to change or cancel it, we can help. We recommend checking out our Customer Service Portal first for information. But generally, if you've booked your package in the last 24 hours, you may be able to cancel and rebook at no cost. If it's been longer than 24 hours, your hotel, airline or car rental company may impose a charge.
How do I get a cheap travel package to Matlacha Isles?
Combine your hotels and flights, throw in extras such as activities, and save with a Matlacha Isles travel package. You won't just score superb discounts on your getaway — you'll have lots of choice within your reach too. When you book with Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels all over the world. Your next epic adventure begins right here, right now!
Does Expedia offer Book Now, Pay Later Matlacha Isles holidays?
Expedia has partnered with online lender Klarna to make booking your next trip easier on the purse strings. Paying in instalments means you can spread the costs of your next adventure, leaving you with more cash to play with while you're away. Klarna has several payment plans to choose from, so you're sure to find one that works with your budget. Take a look at these flexible payment options:
  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's convenient monthly instalment plans. If paying a little each month works for you, choose this option at checkout.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay off your holiday across multiple transactions.
  • Low deposit holidays: If paying a small percentage of your trip (rather than the full total upfront) makes it easier to hit that "book now" button, choose a low deposit holiday payment plan from Klarna.
Where should I stay in Matlacha Isles?
If you're eager to be in the heart of the action, stay somewhere near Sun Splash Water Park. Many travellers book a hotel around this major tourist attraction.
What are the top hotels in Matlacha Isles?
If it's your very first time in Matlacha Isles, reserve a room at Holiday Inn Express Cape Coral-Fort Myers Area, an IHG Hotel or The Westin Cape Coral Resort At Marina Village. Both offer comfy beds and are favourites among many travellers.
How far in advance should I book my Matlacha Isles holiday?
While prices change frequently, we generally suggest booking your seats as early as possible. Many international fares can be found on Expedia up to 12 months in advance. If circumstances have left you booking last minute, you might still be lucky. Low prices to Matlacha Isles occasionally appear just weeks before departure.
What does an Expedia Matlacha Isles travel package include?
That depends on what you're after. If you're travelling by yourself, you might decide to combine flights and hotels. Bringing the whole crew to Matlacha Isles? A travel package that includes hotels, flights and rental cars might be a better fit. Expedia gives you the flexibility to customize your travel package.
What should I know before booking a Matlacha Isles travel package?
You can save big by bundling your hotels, airfares and rental cars. Once you've created your package, you can add on sightseeing tours or experiences. Your next awesome adventure is only a couple of clicks away.
Can I choose my airline with a Matlacha Isles Expedia travel package?
Yes — that's the beauty of an Expedia package. You're the boss! We have access to more than 550 airline partners worldwide, so you have lots of choice when putting together your Matlacha Isles getaway.

Things to do

Sunset Cruise Fort Myers Beach

Sunset Cruise Fort Myers Beach

£36
per adult
100% of travellers recommend
Sunset Cruise Fort Myers Beach
Dolphin Wildlife Cruise Fort Myers Beach

Dolphin Wildlife Cruise Fort Myers Beach

£48
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
Fort Myers: Guided Standup Paddleboarding or Kayaking Tour

Fort Myers Dolphin & Manatee Kayak or Paddleboard Tour

£54
per adult
90% of travellers recommend
Fort Myers Dolphin & Manatee Kayak or Paddleboard Tour
See all activities in Cape Coral

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.