Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
IMAG History & Science Center: Skip-the-Line Ticket
£15
per adult
Fort Myers Dolphin & Manatee Kayak or Paddleboard Tour
£53
per adult
90% of travellers recommend
Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included
£48
per adult
Everglades Day Safari from Fort Myers/Naples Area
£183
per adult
90% of travellers recommend
Top hotels in Matlacha Isles
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is £183 per night from 22 Sept to 23 Sept
£183
22 Sept - 23 Sept
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,000 reviews)
"We loved the location and our view. We were upgraded to a room on the 8th floor with pool and water view and the sunset was amazing!!! You can either go to sanibel, ft Myers, cape coral or our favorite Lovers Key state park!!!"
Reviewed on 9 Sept 2026
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is £168 per night from 14 Sept to 15 Sept
£168
14 Sept - 15 Sept
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is £128 per night from 23 Sept to 24 Sept
£128
23 Sept - 24 Sept
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
8.8/10 Excellent! (2,002 reviews)
"We had a nice trip but we came in on Labor Day, which was a little too busy full for our liking, the beds were not great and the A/C did not cool down enough ..but if you want more action and music playing all day this is your spot! And True Beachfront property"
Reviewed on 9 Sept 2026
Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
The price is £49 per night from 21 Sept to 22 Sept
£49
21 Sept - 22 Sept
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,165 reviews)
"The room was nice and clean."
Reviewed on 9 Sept 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is £168 per night from 4 Oct to 5 Oct
£168
4 Oct - 5 Oct
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,280 reviews)
"The room was amazing and very clean. They did give us the wrong room. Stated we were getting one of the last rooms. Then when we got there we were one of maybe 15 people there. The night we arrived the boy in the office wasn’t very helpful and had a bit of a chip on his shoulder. But we overheard ..."
Reviewed on 9 Sept 2026
Pink Shell Beach Resort and Marina
275 Estero Blvd Fort Myers Beach FL
The price is £218 per night from 30 Sept to 1 Oct
£218
30 Sept - 1 Oct
includes taxes & fees
Stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools and a full-service spa. Our guests praise the breakfast and the pool in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
