Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
IMAG History & Science Center: Skip-the-Line Ticket
£15
per adult
Fort Myers Dolphin & Manatee Kayak or Paddleboard Tour
£53
per adult
90% of travellers recommend
Fort Myers Beach Dolphin & Sightseeing Tour Refreshments Included
£48
per adult
Everglades Day Safari from Fort Myers/Naples Area
£183
per adult
90% of travellers recommend
Top hotels in Matlacha Isles
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is £184 per night from 28 Sept to 29 Sept
£184
28 Sept - 29 Sept
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,001 reviews)
"Very nice clean and very helpful staff"
Reviewed on 11 Sept 2026
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is £163 per night from 14 Sept to 15 Sept
£163
14 Sept - 15 Sept
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is £122 per night from 14 Sept to 15 Sept
£122
14 Sept - 15 Sept
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
8.8/10 Excellent! (2,006 reviews)
"Great stay"
Reviewed on 12 Sept 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is £168 per night from 4 Oct to 5 Oct
£168
4 Oct - 5 Oct
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,286 reviews)
"Lackluster. Thanks for charging an extra $77 for a “resort fee” which didn’t amount to anything. I’m already paying $400 for the location. Then it’s $50 for a couple egg sandwiches and rhe the staff are clueless."
Reviewed on 12 Sept 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
The price is £83 per night from 4 Oct to 5 Oct
£83
4 Oct - 5 Oct
includes taxes & fees
Stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
Pink Shell Beach Resort and Marina
275 Estero Blvd Fort Myers Beach FL
The price is £214 per night from 29 Sept to 30 Sept
£214
29 Sept - 30 Sept
includes taxes & fees
Stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools and a full-service spa. Our guests praise the breakfast and the pool in ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
