Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
Dolphin and Manatee Adventure Tour of Fort Myers
£54
per adult
88% of travellers recommend
Sunset Cruise Fort Myers Beach
£36
per adult
100% of travellers recommend
Marco Island: 10,000 Islands Shelling Boat Tour
£75
per adult
100% of travellers recommend
Top hotels in Matlacha Isles
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is £176 per night from 31 Aug to 1 Sept
£176
31 Aug - 1 Sept
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,371 reviews)
"My daughter forgot her retainer in the hotel room when we left and the hotel was great the shipped right to her they was so helpful in a stressful situation"
Reviewed on 31 Jul 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
Fully refundable
The price is £135 per night from 18 Aug to 19 Aug
£135
18 Aug - 19 Aug
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
8.8/10 Excellent! (1,839 reviews)
"The hotel is amazing the restaurants were excellent the staff was very friendly and helpful and the beach was amazing"
Reviewed on 1 Aug 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is £191 per night from 31 Aug to 1 Sept
£191
31 Aug - 1 Sept
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,003 reviews)
"Proximity to everything. Property grounds and amenities"
Reviewed on 31 Jul 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
The price is £84 per night from 23 Aug to 24 Aug
£84
23 Aug - 24 Aug
includes taxes & fees
Stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,592 reviews)
"Dog friendly and a conveniant location. Free breakfast."
Reviewed on 30 Jul 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is £169 per night from 16 Aug to 17 Aug
£169
16 Aug - 17 Aug
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,161 reviews)
"We had a wonderful stay Our room was spacious, well maintained and clean. The air-conditioning worked perfectly. It kept the room cool and comfortable throughout our stay. The staff from the time you checked in, to the restaurant, to the bar was friendly, attentive and provided excellent service. ..."
Reviewed on 30 Jul 2026
Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
The price is £43 per night from 1 Sept to 2 Sept
£43
1 Sept - 2 Sept
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,140 reviews)
"This was our second stay and we will book again in August. also several ministers will book at this place since we have an upcoming event. They gave us the same room at our request."
Reviewed on 31 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Lovegrove Gallery & Gardens, some noteworthy sights in the nearby area.
