Title: Hotels in Lignumvitae Key Botanical State Park, FL - Best Lignumvitae Key Botanical State Park Hotels from £69 - Fully Refundable Options - Expedia.co.uk [Lignumvitae Key Botanical State Park Travel Guide](https://expedia.co.uk/Lignumvitae-Key-Botanical-State-Park.dx553248621532652349)[Holiday Rentals in Lignumvitae Key Botanical State Park](https://expedia.co.uk/Lignumvitae-Key-Botanical-State-Park-Holiday-Rentals.d553248621532652349.Travel-Guide-HolidayRentals)[Flights to Lignumvitae Key Botanical State Park](https://expedia.co.uk/Cheap-Flights-To-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Travel-Guide-Flights)[Lignumvitae Key Botanical State Park Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Car-Hire-Guide)[Lignumvitae Key Botanical State Park Holidays](https://expedia.co.uk/Lignumvitae-Key-Botanical-State-Park.d553248621532652349.Holidays-City-Breaks) ![Florida Keys Brewing Co. showing signage](https://images.trvl-media.com/place/553248635997958830/30b22f53-286f-436b-ae7a-d035c9062e6c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Lignumvitae Key Botanical State Park, FL from £69 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Lignumvitae Key Botanical State Park Spa [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&lodging=APART_HOTEL) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&amenities=POOL) Resort [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&lodging=HOTEL_RESORT) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&lodging=APARTMENT) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&amenities=OCEAN_VIEW) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&amenities=HOT_TUB) House­boat [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&lodging=HOUSE_BOAT) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&amenities=PETS) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Lignumvitae+Key+Botanical+State+Park%2C+Florida%2C+United+States+of+America®ionId=553248621532652349&latLong=24.903077%2C-80.695302&adults=2&startDate=2025-12-13&d1=2025-12-13&endDate=2025-12-15&d2=2025-12-15&lodging=CONDO) ## Check prices for these dates Tonight [29 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532652349&startDate=2025-11-29&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [30 Nov - 1 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532652349&startDate=2025-11-30&endDate=2025-12-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532652349&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248621532652349&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 Lignumvitae Key Botanical State Park hotels and places to stay ![Private beach, white sand, sun-loungers, beach towels](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/689f4306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/fa9b6bdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Water view](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/8979e9b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/12d77a84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chesapeake Beach Resort Matecumbe 9.2/10 Wonderful (1590) "Great breakfast very well kept grounds" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £148 includes taxes & fees 16 Dec - 17 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Chesapeake-Beach-Resort.h4170.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4190000/4182600/4182524/667446d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4190000/4182600/4182524/b10fe59f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/5000000/4190000/4182600/4182524/ca67d5ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4190000/4182600/4182524/be3c8b08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coconut Cove Resort and Marina Islamorada 9.0/10 Wonderful (142) "Quiet and relaxing. Great place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Edward £104 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Coconut-Cove-Resort-And-Marina.h4182524.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/990500/990422/6ac4045c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, a heated pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/1000000/990500/990422/a571015b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Oceanfront Pool View King Room | Terrace/patio](https://images.trvl-media.com/lodging/1000000/1000000/990500/990422/a348bb16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/990500/990422/45deddf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pines & Palms Resort Matecumbe 9.2/10 Wonderful (1004) "Very nice place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan £160 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Pines-Palms-Resort.h990422.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/84b50729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![One Bedroom Oceanfront Suite King | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/2f598fe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/60b7c04d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Alligator Reef Oceanfront Accessible Room King Bed | View from room](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/1b5ced17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amara Cay Resort Matecumbe 8.8/10 Excellent (1269) "Great place and great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christian £171 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) ![Outdoor pool, free pool cabanas](https://images.trvl-media.com/lodging/31000000/30570000/30568100/30568049/25606792.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/31000000/30570000/30568100/30568049/0fad4f99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/31000000/30570000/30568100/30568049/711b38d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/31000000/30570000/30568100/30568049/92298919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sunset Inn Matecumbe 9.4/10 Exceptional (1006) "Great place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heather £99 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Sunset-Inn.h30568049.Hotel-Information) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2480000/2477600/2477508/eda54a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2480000/2477600/2477508/a11bb47b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2480000/2477600/2477508/a375b426.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, Multiple Beds (Casa de Coco) | Dining room](https://images.trvl-media.com/lodging/3000000/2480000/2477600/2477508/9c557f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Siesta Resort & Villas Matecumbe 8.8/10 Excellent (1002) "Excellent stay with great amenities." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria £158 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-La-Siesta-Resort-Marina.h2477508.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3280000/3274400/3274374/9ae0ece9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach/ocean view](https://images.trvl-media.com/lodging/4000000/3280000/3274400/3274374/449b99c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3280000/3274400/3274374/7c261d0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/4000000/3280000/3274400/3274374/9e08c794.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fisher Inn Resort & Marina Islamorada 8.2/10 Very good (1017) "Great experience, highly recommend staying at the Fisher Inn." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eduardo £96 includes taxes & fees 18 Dec - 19 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Fisher-Inn-Resort-Marina.h3274374.Hotel-Information) ![Private beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/981feca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/e32d7e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/79d31a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cheeca Lodge & Spa Matecumbe 9.2/10 Wonderful (1278) "It was absolutely beautiful and the staff was always super nice!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £220 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/6f2246e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/4b49fc53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room | Private kitchen | Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/4077334d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Waterfront Standard King Bed | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/e7a0378c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lime Tree Bay Resort Long Key 9.2/10 Wonderful (1113) "Excellent stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joshua £130 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Long-Key-Hotels-Lime-Tree-Bay-Resort.h882254.Hotel-Information) ![Dock](https://images.trvl-media.com/lodging/1000000/20000/12200/12200/9afce9bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun-loungers, beach towels, kayaking](https://images.trvl-media.com/lodging/1000000/20000/12200/12200/8952c233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/12200/12200/00476fee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/12200/12200/8f06ee9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hadley Resort and Marina Matecumbe 7.8/10 Good (1009) "Azaya at the front desk was GREAT!! Boat launch on property free for guests. Perfect location comfy rooms! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeff £110 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Hadley-House-Islamorada.h12200.Hotel-Information) ![Beach nearby, white sand, sun-loungers, beach umbrellas](https://images.trvl-media.com/lodging/1000000/910000/900500/900424/46d4fa27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/900500/900424/c40dc838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jungles Suite | Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/1000000/910000/900500/900424/w762h679x132y4-fc33a6d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/910000/900500/900424/w1009h683x7y0-80f60840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Morada Matecumbe 9.4/10 Exceptional (411) "Really great stay, super romantic " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alexander £356 includes taxes & fees 10 Dec - 11 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Casa-Morada.h900424.Hotel-Information) ![Oceanfront King Suite w/ Kitchen & Private Balcony | Beach/ocean view](https://images.trvl-media.com/lodging/5000000/4290000/4287400/4287368/7fd0f78d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Oceanfront King Suite w/ Kitchen & Private Balcony | Terrace/patio](https://images.trvl-media.com/lodging/5000000/4290000/4287400/4287368/42d378ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Oceanfront King Suite w/ Kitchen & Private Balcony | Water view](https://images.trvl-media.com/lodging/5000000/4290000/4287400/4287368/3997e962.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4290000/4287400/4287368/29680b52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drop Anchor Islamorada 8.8/10 Excellent (1004) "Beautiful property and the staff was amazing." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £98 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Drop-Anchor.h4287368.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/5adae4af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Islander Suite Ocean View Two Bedroom | Private kitchen | Coffee/tea maker](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/20ed25e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/b513b652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/6ec44483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Islander Resort Matecumbe 9.2/10 Wonderful (1020) "The room and amenities were great and it was quiet.. just what we needed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra £218 includes taxes & fees 4 Dec - 5 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Islander-Resort.h475438.Hotel-Information) ![5 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/b1845555.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/306bb501.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/3d68eb94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/af9b3995.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hawks Cay Resort Marathon 8.0/10 Very good (1009) "Enjoyed a few days with the kids gere" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica £305 includes taxes & fees 10 Dec - 11 Dec [](https://www.expedia.co.uk/Marathon-Hotels-Hawks-Cay-Resort.h6068.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/37000000/36890000/36881900/36881801/e7fc7008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/37000000/36890000/36881900/36881801/4d5bbaec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Oceanfront | Hypo-allergenic bedding, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/37000000/36890000/36881900/36881801/a43035bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach bar](https://images.trvl-media.com/lodging/37000000/36890000/36881900/36881801/ef4dc63f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grassy Flats Resort & Beach Club Marathon 9.4/10 Exceptional (344) "Great staff, check in, site tour and dinner in the restaurant." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £175 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Marathon-Hotels-Grassy-Flats-Resort-Beach-Club.h36881801.Hotel-Information) ![Private beach, sun-loungers, beach towels, scuba diving](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/d10a018b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, a heated pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/8de2bfdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/cb9f9f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/c5948ba3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort Islamorada 9.0/10 Wonderful (112) "Beautiful place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan £223 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Three-Waters-Resort-And-Marina.h11864.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/57000000/56960000/56952700/56952622/b0a43673.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dock](https://images.trvl-media.com/lodging/57000000/56960000/56952700/56952622/b27f4d1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56960000/56952700/56952622/b1bfc483.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/57000000/56960000/56952700/56952622/67c8f76f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ragged Edge Resort & Marina Islamorada 9.4/10 Exceptional (204) "Clean room, beautiful pool and quiet!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert [](https://www.expedia.co.uk/Islamorada-Hotels-Ragged-Edge-Resort-Marina.h56952622.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/96b58c48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Bedroom, Kitchen, Pool View | Living area | TV](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/5e728c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cottage | Living area | TV](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/7a0bffa6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Cottage | 1 bedroom, free WiFi](https://images.trvl-media.com/lodging/12000000/11950000/11945900/11945889/b8fa0acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Breezy Palms Resort Matecumbe 8.8/10 Excellent (576) "Best hotel for the price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) luzdari £121 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Breezy-Palms-Resort.h11945889.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Kitchenette, Oceanfront | Terrace/patio](https://images.trvl-media.com/lodging/13000000/12660000/12653500/12653483/0cb6bab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, 2 Queen Beds, Refrigerator & Microwave | In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/13000000/12660000/12653500/12653483/b1df7837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/13000000/12660000/12653500/12653483/2b7458ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, 2 Queen Beds, Refrigerator & Microwave | In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/13000000/12660000/12653500/12653483/d3f952a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sands of Islamorada Matecumbe 8.8/10 Excellent (390) "The hotel was reasonably priced and while a little dated, the rooms were large and clean. The staff was SUPER nice. All in all, a great place to stay a couple nights in the keys at a reasonable price. Would definitely recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda £166 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Sands-Of-Islamorada.h12653483.Hotel-Information) ![Classic Room, Patio, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/111000000/110690000/110683500/110683445/224c2448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room, Patio, Garden View | Free WiFi](https://images.trvl-media.com/lodging/111000000/110690000/110683500/110683445/5d3fac38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Classic Room, Patio, Garden View | Free WiFi](https://images.trvl-media.com/lodging/111000000/110690000/110683500/110683445/5f27ae80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/111000000/110690000/110683500/110683445/01400ad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ocean View Inn & Pub Islamorada 9.4/10 Exceptional (9) "Awesome place to stay, restaurant and bar attached, outside bar and dining area overlooking the bay. Pool also very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rick £134 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-The-Ocean-View-Inn-Pub.h110683445.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-13&endDate=2025-12-14®ionId=553248621532652349&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=HTG_BF_PROMO_553248621532652349) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLignumvitae-Key-Botanical-State-Park-Hotels.d553248621532652349.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLignumvitae-Key-Botanical-State-Park-Hotels.d553248621532652349.Travel-Guide-Hotels) ## Learn more about Lignumvitae Key Botanical State Park Discover the seaside area of Lignumvitae Key Botanical State Park—beaches, fresh seafood and top sights like Everglades National Park. [See all hotels in Lignumvitae Key Botanical State Park](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-13&endDate=2025-12-14&adults=2®ionId=553248621532652349) ![Florida Keys Brewing Co. showing signage](https://images.trvl-media.com/place/553248635997958830/30b22f53-286f-436b-ae7a-d035c9062e6c.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Lignumvitae Key Botanical State Park Hotel Reviews ![Ocean Pointe Suites at Key Largo](https://images.trvl-media.com/lodging/1000000/10000/5600/5502/c6c81bd5_y.jpg) ### Ocean Pointe Suites at Key Largo 10/10 Excellent "The room was great for my whole family. All the staff were so nice and the restaurant and bar had great food. They even cooked up the fish we caught. It was some of the best food and service we have had in a long time. " [](https://expedia.co.uk/Tavernier-Hotels-Ocean-Pointe-Suites-At-Key-Largo.h5502.Hotel-Information) ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723_y.jpg) ### Cheeca Lodge & Spa 10/10 Excellent "We stayed in the newest section of the Cheeca Lodge. It is so incredibly nice! We had other family staying in the lagoon area. We enjoyed all the activities on the property as well. My nephew especially loved the par3 golf course. I really loved the staff at Cheeca Lodge too. Shelia, Amber and David were our poolside attendants, and Jessica at the front desk was very helpful. " [](https://expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Drift Hotel](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209518/f3e504e7_y.jpg) ### Drift Hotel 10/10 Excellent "we had a good time here, fabulous place" [](https://expedia.co.uk/Key-Largo-Hotels-Drift-Hotel.h13209518.Hotel-Information) ![Hadley Resort and Marina](https://images.trvl-media.com/lodging/1000000/20000/12200/12200/9afce9bd_y.jpg) ### Hadley Resort and Marina 10/10 Excellent "Everything was excellent " [](https://expedia.co.uk/Islamorada-Hotels-Hadley-House-Islamorada.h12200.Hotel-Information) ![Lime Tree Bay Resort](https://images.trvl-media.com/lodging/1000000/890000/882300/882254/6f2246e8_y.jpg) ### Lime Tree Bay Resort 10/10 Excellent "The room was well appointed and super clean. We loved the little beach. " [](https://expedia.co.uk/Long-Key-Hotels-Lime-Tree-Bay-Resort.h882254.Hotel-Information) ![Islander Resort](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/5adae4af_y.jpg) ### Islander Resort 10/10 Excellent "Everything was delightful!" [](https://expedia.co.uk/Islamorada-Hotels-Islander-Resort.h475438.Hotel-Information) ![Creekside Inn](https://images.trvl-media.com/lodging/2000000/1580000/1576800/1576773/5e43c05b_y.jpg) ### Creekside Inn 10/10 Excellent "Clean room, lovely location, accessible to nearby restaurants" [](https://expedia.co.uk/Tavernier-Hotels-Creekside-Inn-Islamorada.h1576773.Hotel-Information) ![Marina Del Mar Resort and Marina](https://images.trvl-media.com/lodging/1000000/10000/5200/5114/d42f8885_y.jpg) ### Marina Del Mar Resort and Marina 10/10 Excellent "Staff is so responsive and accommodating-thank you!" [](https://expedia.co.uk/Key-Largo-Hotels-Marina-Del-Mar-Resort-And-Marina.h5114.Hotel-Information) ![Chesapeake Beach Resort](https://images.trvl-media.com/lodging/1000000/10000/4200/4170/689f4306_y.jpg) ### Chesapeake Beach Resort 10/10 Excellent "Excellent hotel" [](https://expedia.co.uk/Islamorada-Hotels-Chesapeake-Beach-Resort.h4170.Hotel-Information) ## More cheap stays in Lignumvitae Key Botanical State Park ![Marina Del Mar Resort and Marina](https://images.trvl-media.com/lodging/1000000/10000/5200/5114/d42f8885_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Marina Del Mar Resort and Marina 527 Caribbean Drive Key Largo FL £97 14 Dec - 15 Dec includes taxes & fees 8.4/10 Very Good! (1,637 reviews) [](https://expedia.co.uk/Key-Largo-Hotels-Marina-Del-Mar-Resort-And-Marina.h5114.Hotel-Information) ![Creekside Inn](https://images.trvl-media.com/lodging/2000000/1580000/1576800/1576773/5e43c05b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Creekside Inn 90611 Old Highway Tavernier FL £106 9 Dec - 10 Dec includes taxes & fees 7.8/10 Good! (1,009 reviews) [](https://expedia.co.uk/Tavernier-Hotels-Creekside-Inn-Islamorada.h1576773.Hotel-Information) ![Rock Reef Resort](https://images.trvl-media.com/lodging/58000000/57190000/57185500/57185414/6ddda999_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Rock Reef Resort 97850 Overseas Hwy Key Largo FL £69 1 Dec - 2 Dec includes taxes & fees 9.2/10 Wonderful! (1,071 reviews) [](https://expedia.co.uk/Key-Largo-Hotels-Rock-Reef-Resort.h57185414.Hotel-Information) ![Drift Hotel](https://images.trvl-media.com/lodging/14000000/13210000/13209600/13209518/f3e504e7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Drift Hotel 95320 Overseas Hwy Key Largo FL £85 30 Nov - 1 Dec includes taxes & fees 8.8/10 Excellent! (1,007 reviews) [](https://expedia.co.uk/Key-Largo-Hotels-Drift-Hotel.h13209518.Hotel-Information) ![The Pelican Key Largo Cottages](https://images.trvl-media.com/lodging/7000000/6840000/6839400/6839376/f35b06df_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Pelican Key Largo Cottages 99340 Overseas Highway Key Largo FL £73 30 Nov - 1 Dec includes taxes & fees 8.8/10 Excellent! (1,012 reviews) [](https://expedia.co.uk/Key-Largo-Hotels-The-Pelican-Key-Largo-Cottages.h6839376.Hotel-Information) ![La Jolla Resort](https://images.trvl-media.com/lodging/17000000/16580000/16574700/16574668/74e26d92_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### La Jolla Resort 82216 Overseas Highway Islamorada FL £86 18 Dec - 19 Dec includes taxes & fees 9/10 Wonderful! (1,003 reviews) [](https://expedia.co.uk/Islamorada-Hotels-La-Jolla-Resort.h16574668.Hotel-Information) ## Hotels in Lignumvitae Key Botanical State Park with star rating ![5 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/25600/25559/c6e0103a_z.jpg) 5 Star Hotels 3 properties [](https://expedia.co.uk/5Star-Lignumvitae-Key-Botanical-State-Park-Hotels.s50-0-d553248621532652349.Travel-Guide-Filter-Hotels) ![4 Star Hotels](https://images.trvl-media.com/lodging/1000000/30000/23700/23677/6ae928dd_z.jpg) 4 Star Hotels 9 properties [](https://expedia.co.uk/4Star-Lignumvitae-Key-Botanical-State-Park-Hotels.s40-0-d553248621532652349.Travel-Guide-Filter-Hotels) ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 78 properties [](https://expedia.co.uk/3Star-Lignumvitae-Key-Botanical-State-Park-Hotels.s30-0-d553248621532652349.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 157 properties [](https://expedia.co.uk/2Star-Lignumvitae-Key-Botanical-State-Park-Hotels.s20-0-d553248621532652349.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? > Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Lignumvitae Key Botanical State Park hotel for you. ### How can I save on a Lignumvitae Key Botanical State Park hotel booking with Expedia? > With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Lignumvitae Key Botanical State Park hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings. ### How much is the nightly rate at a Lignumvitae Key Botanical State Park hotel? > Prices for hotels in Lignumvitae Key Botanical State Park often vary, but you can find a great deal from £69 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate. ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [4 Star Hotels in Islamorada](https://www.expedia.co.uk/4Star-Islamorada-Hotels.s40-0-d10768.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Islamorada](https://www.expedia.co.uk/5Star-Islamorada-Hotels.s50-0-d10768.Travel-Guide-Filter-Hotels) - [Hotels near Bud n' Mary's Dive Center](https://www.expedia.co.uk/Bud-N-Marys-Dive-Center-Hotels.0-l6069243-0.Travel-Guide-Filter-Hotels) - [Conch Key Hotels](https://www.expedia.co.uk/Conch-Key-Hotels.d3000396828.Travel-Guide-Hotels) - [Cross Key Waterways Hotels](https://www.expedia.co.uk/Cross-Key-Waterways-Key-Largo-Hotels.0-n553248635976480816-0.Travel-Guide-Filter-Hotels) - [Duck Key Hotels](https://www.expedia.co.uk/Duck-Key-Hotels.d184267.Travel-Guide-Hotels) - [Flamingo Hotels](https://www.expedia.co.uk/Flamingo-Hotels.d553248635074842070.Travel-Guide-Hotels) - 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[Record Rent A Car Rental Cars in Lower Matecumbe Key](https://www.expedia.co.uk/Record-Rent-A-Car-Car-Rentals-In-Lower-Matecumbe-Key.d553248635975749077-c30.Car-Rental-Guide-Suppliers) - [U-Save Rental Cars in Lower Matecumbe Key](https://www.expedia.co.uk/U-Save-Car-Rentals-In-Lower-Matecumbe-Key.d553248635975749077-c34.Car-Rental-Guide-Suppliers) - [Islamorada Holiday Rentals](https://www.expedia.co.uk/Islamorada-Holiday-Rentals.d10768.Travel-Guide-HolidayRentals) - [Things to do in Islamorada](https://www.expedia.co.uk/Things-To-Do-In-Islamorada.d10768.Travel-Guide-Activities) - [Things to do in Plantation Key](https://www.expedia.co.uk/Things-To-Do-In-Plantation-Key.d553248635083898347.Travel-Guide-Activities) - [Things to do in Windley Key](https://www.expedia.co.uk/Things-To-Do-In-Windley-Key.d553248635976197663.Travel-Guide-Activities) - [Book Hotels in Lignumvitae Key Botanical State Park on Expedia.com](https://www.expedia.com/Lignumvitae-Key-Botanical-State-Park-Hotels.d553248621532652349.Travel-Guide-Hotels) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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