Title: Hotels in La Mesilla, NM - Best La Mesilla Hotels from £59 - Fully Refundable Options - Expedia.co.uk

 

[Holiday Rentals in La Mesilla](https://expedia.co.uk/La-Mesilla-Holiday-Rentals.d553248635975872198.Travel-Guide-HolidayRentals)[La Mesilla Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Mesilla.d553248635975872198.Car-Hire-Guide)[La Mesilla Holidays](https://expedia.co.uk/La-Mesilla.d553248635975872198.Holidays-City-Breaks)

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# Find hotels in La Mesilla, NM from £59

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## Go beyond your typical stay in La Mesilla

Pool

[](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2025-12-10&d1=2025-12-10&endDate=2025-12-12&d2=2025-12-12&amenities=POOL)

Hot tub

[](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2025-12-10&d1=2025-12-10&endDate=2025-12-12&d2=2025-12-12&amenities=HOT_TUB)

Family friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2025-12-10&d1=2025-12-10&endDate=2025-12-12&d2=2025-12-12&travelerType=family_friendly)

Pet friendly

[](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2025-12-10&d1=2025-12-10&endDate=2025-12-12&d2=2025-12-12&amenities=PETS)

Cottage

[](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2025-12-10&d1=2025-12-10&endDate=2025-12-12&d2=2025-12-12&lodging=COTTAGE)

Condo

[](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America&regionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2025-12-10&d1=2025-12-10&endDate=2025-12-12&d2=2025-12-12&lodging=CONDO)

## Check prices for these dates

Tonight

[25 Nov - 26 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198&startDate=2025-11-25&endDate=2025-11-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[26 Nov - 27 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198&startDate=2025-11-26&endDate=2025-11-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Top 10 La Mesilla hotels and places to stay

![Free daily self-service breakfast ](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/7c97c173.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/4c8e5531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/4611a00b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/e5b066f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Wingate by Wyndham Los Alamos

Los Alamos

8.0/10

Very good

(566)

"Inexpensive decent lodging for one night. Los Alamos only has 2 hotels. We would stay there again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Donna

£78

includes taxes & fees

21 Dec - 22 Dec

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Comfort-Inn-Suites-Los-Alamos.h74653.Hotel-Information)

![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/65b278ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property – evening/night](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/1e1b9063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Mini-fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/c25e2986.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/cc65f258.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

Los Alamos

8.8/10

Excellent

(737)

"The room was spotless , all the employees are friendly and have great customer service. The breakfast is really good . "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Claudia

£95

includes taxes & fees

28 Nov - 29 Nov

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Holiday-Inn-Express-Hotel-Suites-Los-Alamos.h2976403.Hotel-Information)

![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/e0f972f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/3a9dbc27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/18384ff5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/ef74e67b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Rodeway Inn Española

Espanola

6.2/10

(465)

"Friendly staff, clean on the surface, appears to be in renovation stage, heat and air worked fine, lighted/fenced parking, filthy sheets, cigarette burned bed covers, no (soap, shampoo, conditioner, hair dryer), and breakfast was just coffee and oatmeal packets. This place is perfect as a homeless refuge or a 1 hour rental. Do yourself a favor and stay at one of the local casinos."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

M L

£59

includes taxes & fees

25 Dec - 26 Dec

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Rodeway-Inn.h16124.Hotel-Information)

![View from room](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/c2604840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/bd87a46b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/59a04f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/d37475b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Days Inn by Wyndham Espanola

Espanola

5.8/10

(586)

"Good place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sergio

£73

includes taxes & fees

19 Dec - 20 Dec

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Days-Inn-By-Wyndham-Espanola.h19678.Hotel-Information)

![Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/912a4f46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/39bddef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/ca9f58d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/6d04c5f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Glorieta

Santa Fe

8.0/10

Very good

(36)

"Loved the decor"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Marian

£119

includes taxes & fees

30 Nov - 1 Dec

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Hotel-Glorieta.h3139.Hotel-Information)

![Suite, 1 King Bed | View from room](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/c6ba74ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/866cf9af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/ebfa22d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/2bd32ee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Santa Fe Buffalo Thunder

Santa Fe

8.6/10

Excellent

(1017)

"Clean and friendly - nice place. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denise

£101

includes taxes & fees

10 Dec - 11 Dec

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Hilton-Santa-Fe-Buffalo-Thunder.h2058957.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/5368dc35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/2fdb3ecb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/c7bcc3f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite | 1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/8e5c8563.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ohkay Casino Resort Hotel

Ohkay Owingeh

8.0/10

Very good

(784)

"Clean rooms and excellent service "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Patrick

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Ohkay-Casino-Resort-Hotel.h458023.Hotel-Information)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/97badd85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Executive Room, 1 King Bed, Non Smoking (Multi-level) | Living area | 55-inch flat-screen TV with cable channels, TV, DVD player](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/cbf589c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from room](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/d8ae1d9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/e09560b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Homewood Suites by Hilton Santa Fe-North

Santa Fe

9.2/10

Wonderful

(1002)

"Good breakfast, clean, staff friendly "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

KIMTHU

£97

includes taxes & fees

16 Dec - 17 Dec

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Homewood-Suites-By-Hilton-Santa-Fe-North.h1184592.Hotel-Information)

![1 bedroom, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/4901e7b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/b013eb88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/8c161554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/989192ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn & Suites Los Alamos White Rock

Los Alamos

9.0/10

Wonderful

(673)

"Nice place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Laura

£95

includes taxes & fees

5 Dec - 6 Dec

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Hampton-Inn-Suites-Los-Alamos-White-Rock.h908632.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/4dd42a18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bathroom sink](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/a406f7fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/a14f1c54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room, 1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/26a45628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cities Of Gold Casino

Santa Fe

8.0/10

Very good

(1061)

"Clean Room and Quiet … "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Owen

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Cities-Of-Gold-Casino.h120761.Hotel-Information)

![Spa](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/96f30ddd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/317dd2ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/3fabc09c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/13be8ab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Espanola, NM

Espanola

6.4/10

(516)

"One of the cleanest motels I’ve been in a long time. The water was hot. It was good and they provided coffee. I will definitely stay here again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Sally

£77

includes taxes & fees

27 Nov - 28 Nov

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Motel-6-Espanola.h459557.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/dc73db0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Bunkhouse) | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/807aba16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/93204597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/4b0bf4d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Bishop's Lodge, Auberge Collection

Tesuque

9.4/10

Exceptional

(88)

"Great location, Resort, amenities, excellent service and great restaurant chef!!!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

James R

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Bishops-Lodge.h40737.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/eb9982cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/7f6e9855.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Couples treatment room(s), body treatments, hot stone massages](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/459f0ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 2 Queen Beds, Non Smoking | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/753685a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Seasons Resort Rancho Encantado Santa Fe

Santa Fe

9.4/10

Exceptional

(265)

"Food options were good, but limited. The scenery was breathtaking as well as the nearby Santa Fe and the tours we took to the Indian reservation and Los Alamos"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

ILAN

£535

includes taxes & fees

9 Dec - 10 Dec

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Four-Seasons-Resort-Rancho-Encantado-Santa-Fe.h40731.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/a0789287.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/0621a341.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually decorated, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/47f356a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/4d99e8b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Inn at the Delta

Espanola

9.4/10

Exceptional

(1002)

"The room was very clean with plenty of space. Nice and quiet area. Really enjoyed our 3 night stay."

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Taco

[](https://www.expedia.co.uk/Santa-Fe-Hotels-The-Inn-At-The-Delta.h1581298.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/a25f16f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/w797h532x3y3-17b34bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![The Casita | 1 bedroom, premium bedding, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/217a360e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/71fb0337.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Escondida Bed & Breakfast

Chimayo

9.4/10

Exceptional

(262)

"Beautiful historic property. Great staff and excellent breakfast. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Julie

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Casa-Escondida-Bed-Breakfast.h521375.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top La Mesilla Hotel Reviews

![Hilton Santa Fe Buffalo Thunder](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/c6ba74ab_y.jpg)

### Hilton Santa Fe Buffalo Thunder

10/10 Excellent

"Great stay"

[](https://expedia.co.uk/Santa-Fe-Hotels-Hilton-Santa-Fe-Buffalo-Thunder.h2058957.Hotel-Information)

![Cities Of Gold Casino](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/4dd42a18_y.jpg)

### Cities Of Gold Casino

10/10 Excellent

"Clean Room and Quiet … "

[](https://expedia.co.uk/Santa-Fe-Hotels-Cities-Of-Gold-Casino.h120761.Hotel-Information)

![Bishop's Lodge, Auberge Collection](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/dc73db0b_y.jpg)

### Bishop's Lodge, Auberge Collection

10/10 Excellent

"Great location, Resort, amenities, excellent service and great restaurant chef!!!!!"

[](https://expedia.co.uk/Santa-Fe-Hotels-Bishops-Lodge.h40737.Hotel-Information)

![Hotel Glorieta](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/912a4f46_y.jpg)

### Hotel Glorieta

10/10 Excellent

"Everything was great. "

[](https://expedia.co.uk/Santa-Fe-Hotels-Hotel-Glorieta.h3139.Hotel-Information)

![Four Seasons Resort Rancho Encantado Santa Fe](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/eb9982cf_y.jpg)

### Four Seasons Resort Rancho Encantado Santa Fe

10/10 Excellent

"just lovely all around"

[](https://expedia.co.uk/Santa-Fe-Hotels-Four-Seasons-Resort-Rancho-Encantado-Santa-Fe.h40731.Hotel-Information)

![Wingate by Wyndham Los Alamos](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/e5b066f8_y.jpg)

### Wingate by Wyndham Los Alamos

10/10 Excellent

"Very clean and well maintained. Comfortable bed too. Breakfast was tasty with green chiles for the eggs!"

[](https://expedia.co.uk/Santa-Fe-Hotels-Comfort-Inn-Suites-Los-Alamos.h74653.Hotel-Information)

![Sunset Mountain Ranch- Serene retreat in Sangre de Cristo foothills](https://images.trvl-media.com/lodging/116000000/115080000/115079500/115079481/a95257de_y.jpg)

### Sunset Mountain Ranch- Serene retreat in Sangre de Cristo foothills

10/10 Excellent

"Beautiful house and surroundings, lovely view, and hiking trails right by the oroperty"

[](https://expedia.co.uk/Santa-Fe-Hotels-Sunset-Mountain-Ranch-Serene-Retreat-In-Sangre-De-Cristo-Foothills.h115079481.Hotel-Information)

![Casa Escondida Bed & Breakfast](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/a25f16f6_y.jpg)

### Casa Escondida Bed & Breakfast

10/10 Excellent

"This was our first Bed & Breakfast and let me tell you it did not disappoint. We cannot say enough great things about our experience. The staff was kind and had great suggestions on what to do while in town. The food was excellent, the property was quaint and full of character. We cannot wait to come back and visit. "

[](https://expedia.co.uk/Santa-Fe-Hotels-Casa-Escondida-Bed-Breakfast.h521375.Hotel-Information)

![Motel 6 Espanola, NM](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/96f30ddd_y.jpg)

### Motel 6 Espanola, NM

10/10 Excellent

"One of the better hotels I have stayed in."

[](https://expedia.co.uk/Santa-Fe-Hotels-Motel-6-Espanola.h459557.Hotel-Information)

## More cheap stays in La Mesilla

![Wingate by Wyndham Los Alamos](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/e5b066f8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Wingate by Wyndham Los Alamos

2455 Trinity Dr Los Alamos NM

£78

21 Dec - 22 Dec

includes taxes & fees

8/10 Very Good! (565 reviews)

[](https://expedia.co.uk/Santa-Fe-Hotels-Comfort-Inn-Suites-Los-Alamos.h74653.Hotel-Information)

![Holiday Inn Express & Suites Los Alamos Entrada Park by IHG](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/65b278ef_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

60 Entrada Dr Los Alamos NM

£95

28 Nov - 29 Nov

includes taxes & fees

8.8/10 Excellent! (733 reviews)

[](https://expedia.co.uk/Santa-Fe-Hotels-Holiday-Inn-Express-Hotel-Suites-Los-Alamos.h2976403.Hotel-Information)

![Ohkay Casino Resort Hotel](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/5368dc35_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Ohkay Casino Resort Hotel

Highway 68 Ohkay Owingeh NM

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=10%2F12%2F2025&endDate=11%2F12%2F2025&selected=458023&PinnedHotelID=458023&HadPinnedHotel=true&regionId=553248635975872198)

7.8/10 Good! (784 reviews)

[](https://expedia.co.uk/Santa-Fe-Hotels-Ohkay-Casino-Resort-Hotel.h458023.Hotel-Information)

![Hampton Inn & Suites Los Alamos White Rock](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/4901e7b8_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hampton Inn & Suites Los Alamos White Rock

124 State Hwy 4 Los Alamos NM

£95

5 Dec - 6 Dec

includes taxes & fees

9/10 Wonderful! (672 reviews)

[](https://expedia.co.uk/Santa-Fe-Hotels-Hampton-Inn-Suites-Los-Alamos-White-Rock.h908632.Hotel-Information)

![Motel 6 Espanola, NM](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/96f30ddd_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Motel 6 Espanola, NM

811 S Riverside Drive Espanola NM

£77

27 Nov - 28 Nov

includes taxes & fees

6.4/10 (516 reviews)

[](https://expedia.co.uk/Santa-Fe-Hotels-Motel-6-Espanola.h459557.Hotel-Information)

![Days Inn by Wyndham Espanola](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/c2604840_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Days Inn by Wyndham Espanola

807 S Riverside Dr Espanola NM

£73

19 Dec - 20 Dec

includes taxes & fees

5.6/10 (585 reviews)

[](https://expedia.co.uk/Santa-Fe-Hotels-Days-Inn-By-Wyndham-Espanola.h19678.Hotel-Information)

## Frequently asked questions

### What's the best place for a stay in La Mesilla?

> Located 7.4 mi (11.9 km) from the heart of La Mesilla, [Hilton Santa Fe Buffalo Thunder](https://www.expedia.co.uk/Santa-Fe-Hotels-Hilton-Santa-Fe-Buffalo-Thunder.h2058957.Hotel-Information) is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are [Cities Of Gold Casino](https://www.expedia.co.uk/Santa-Fe-Hotels-Cities-Of-Gold-Casino.h120761.Hotel-Information) and [Hotel Glorieta](https://www.expedia.co.uk/Santa-Fe-Hotels-Hotel-Glorieta.h3139.Hotel-Information). See all available [top hotels](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198), or [vacation rentals in La Mesilla](https://www.expedia.co.uk/La-Mesilla-Holiday-Rentals.d553248635975872198.Travel-Guide-HolidayRentals).

### What are some of the best holiday rentals that La Mesilla has to offer?

> [Dorthia Garden Retreat & Views | Stunning 360 View](https://www.expedia.co.uk/Santa-Fe-Hotels-Dorthia-Garden-Retreat-Views-Stunning-360-View.h67628732.Hotel-Information): This holiday home rental outside of La Mesilla is located near skiing, and has a fireplace, a balcony and a BBQ to put you at ease in your new surroundings. It has 5 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all [vacation rentals in La Mesilla](https://www.expedia.co.uk/La-Mesilla-Holiday-Rentals.d553248635975872198.Travel-Guide-HolidayRentals).

### If I need to cancel my hotel reservation in La Mesilla, will I receive a refund?

> Yes! The majority of hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by [fully refundable](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198&paymentType=FREE_CANCELLATION) to find flexible hotel deals in La Mesilla.

### What is staying in La Mesilla like?

> Visitors will definitely enjoy all that La Mesilla has to offer. There are 359 hotels and other accommodation options in the surrounding area. Find out more about [La Mesilla](https://www.expedia.co.uk/La-Mesilla.dx553248635975872198).

### What should I see while I'm in La Mesilla?

> Places to visit in the wider area include [Cities of Gold Casino](https://www.expedia.co.uk/Cities-Of-Gold-Casino-Santa-Fe.d553248621532645938.Attraction), [Towa Golf Resort](https://www.expedia.co.uk/Towa-Golf-Resort-Santa-Fe.d553248621532645937.Attraction) and [Buffalo Thunder Resort and Casino](https://www.expedia.co.uk/Buffalo-Thunder-Resort-And-Casino-Santa-Fe.d818566223132356608.Attraction). You'll also find [Santuario de Chimayo](https://www.expedia.co.uk/Santuario-De-Chimayo-Chimayo.d6093681.Attraction) and [Lowlows Lowrider Art Place](https://www.expedia.co.uk/Lowlows-Lowrider-Art-Place-Chimayo.d6328184.Attraction) in the area. Take a look at what more there is to see and do in Expedia's [La Mesilla guide](https://www.expedia.co.uk/La-Mesilla.dx553248635975872198).

### What's the weather like in La Mesilla?

> The hottest months are usually July and June, with an average temperature of 21°C, while the coldest months are January and December, with an average of 0°C. The snowiest months in La Mesilla are March, January, December and February, with each month seeing an average of 22 cm of snowfall.

## Explore a world of travel with Expedia

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