Title: Hotels in La Mesilla, NM - Best La Mesilla Hotels from £50 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in La Mesilla](https://expedia.co.uk/La-Mesilla-Holiday-Rentals.d553248635975872198.Travel-Guide-HolidayRentals)[La Mesilla Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Mesilla.d553248635975872198.Car-Hire-Guide)[La Mesilla Holidays](https://expedia.co.uk/La-Mesilla.d553248635975872198.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in La Mesilla, NM from £50 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in La Mesilla Pool [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&amenities=PETS) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&lodging=COTTAGE) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesilla%2C+New+Mexico%2C+United+States+of+America®ionId=553248635975872198&latLong=35.948358%2C-106.070579&adults=2&startDate=2026-01-25&d1=2026-01-25&endDate=2026-01-27&d2=2026-01-27&lodging=CONDO) ## Check prices for these dates Tonight [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198&startDate=2026-01-11&endDate=2026-01-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [12 Jan - 13 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198&startDate=2026-01-12&endDate=2026-01-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975872198&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for La Mesilla hotels ![Indoor pool, seasonal outdoor pool, pool cabanas (surcharge)](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/8424680e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/866cf9af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/d6b51259.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/2bd32ee5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Santa Fe Buffalo Thunder [](https://www.expedia.co.uk/Santa-Fe-Hotels-Hilton-Santa-Fe-Buffalo-Thunder.h2058957.Hotel-Information) Santa Fe 8.8/10 Excellent (1,008 reviews) "room was clean & quiet, beautiful hotel, beautiful pool & huge hot tub " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Johnna £93 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Santa-Fe-Hotels-Hilton-Santa-Fe-Buffalo-Thunder.h2058957.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/5368dc35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/98987c70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/08aa50f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/5b9132ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ohkay Casino Resort Hotel [](https://www.expedia.co.uk/Santa-Fe-Hotels-Ohkay-Casino-Resort-Hotel.h458023.Hotel-Information) Ohkay Owingeh 8.0/10 Very good (791 reviews) "Room nice. Lots of pillows (love that). People very nice too" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) TERRI [](https://www.expedia.co.uk/Santa-Fe-Hotels-Ohkay-Casino-Resort-Hotel.h458023.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/4dd42a18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/112d7b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathroom sink](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/a406f7fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | View from room](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/26a45628.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cities Of Gold Casino [](https://www.expedia.co.uk/Santa-Fe-Hotels-Cities-Of-Gold-Casino.h120761.Hotel-Information) Santa Fe 8.0/10 Very good (1,069 reviews) "Clean room and a great location—close to the casino, which made our New Year’s Eve celebration super convenient. Would definitely stay again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erica £60 includes taxes & fees 10 Feb - 11 Feb [](https://www.expedia.co.uk/Santa-Fe-Hotels-Cities-Of-Gold-Casino.h120761.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/ca9f58d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/b8126edd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/11393c3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/e3129a4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Glorieta [](https://www.expedia.co.uk/Santa-Fe-Hotels-Hotel-Glorieta.h3139.Hotel-Information) Santa Fe 8.2/10 Very good (56 reviews) "Great quiet place to stay, beautiful setting and great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shirley £98 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Santa-Fe-Hotels-Hotel-Glorieta.h3139.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/6ea44016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/w797h532x3y3-17b34bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Kiva Room | Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/f8395467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/1f0603bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa Escondida Bed & Breakfast [](https://www.expedia.co.uk/Santa-Fe-Hotels-Casa-Escondida-Bed-Breakfast.h521375.Hotel-Information) Chimayo 9.4/10 Exceptional (262 reviews) "Beautiful historic property. Great staff and excellent breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie £99 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Santa-Fe-Hotels-Casa-Escondida-Bed-Breakfast.h521375.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/7e65bc33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV, fireplace](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/6861e853.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/e9bf53df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1590000/1581300/1581298/af39f9b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Inn at the Delta [](https://www.expedia.co.uk/Santa-Fe-Hotels-The-Inn-At-The-Delta.h1581298.Hotel-Information) Espanola 9.4/10 Exceptional (1,001 reviews) "Lovely place with a lot of New Mexico charm." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barbara [](https://www.expedia.co.uk/Santa-Fe-Hotels-The-Inn-At-The-Delta.h1581298.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/31eee379.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), body treatments, hot stone massages](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/459f0ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, garden views ](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/76b8c646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/06dccf6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Resort Rancho Encantado Santa Fe [](https://www.expedia.co.uk/Santa-Fe-Hotels-Four-Seasons-Resort-Rancho-Encantado-Santa-Fe.h40731.Hotel-Information) Santa Fe 9.4/10 Exceptional (268 reviews) "Great service and property " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharmin £457 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Santa-Fe-Hotels-Four-Seasons-Resort-Rancho-Encantado-Santa-Fe.h40731.Hotel-Information) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/f6c9158f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/91599156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/6bcfea96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/d7a686fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Espanola, NM [](https://www.expedia.co.uk/Santa-Fe-Hotels-Motel-6-Espanola.h459557.Hotel-Information) Espanola 6.4/10 (518 reviews) "Very surprised ,a lot better than my hotel in Silverton at 1/4 the cost. And many points to the maid service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) james £84 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Santa-Fe-Hotels-Motel-6-Espanola.h459557.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/4b0bf4d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite (Kiva) | View from room](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/fa4f6dac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/dc73db0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/ebb137d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bishop's Lodge, Auberge Collection [](https://www.expedia.co.uk/Santa-Fe-Hotels-Bishops-Lodge.h40737.Hotel-Information) Tesuque 9.4/10 Exceptional (96 reviews) "Everyone was so kind and attentive and the rooms and grounds were so beautiful and clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Liza [](https://www.expedia.co.uk/Santa-Fe-Hotels-Bishops-Lodge.h40737.Hotel-Information) ![Suite, 1 Queen Bed with Sofa bed, Hearing Accessible, Non Smoking (Mobility, Roll-In Shower) | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/d168a9eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/e5b066f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/4c8e5531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking | Premium bedding, down duvets, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/617bbbd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham Los Alamos [](https://www.expedia.co.uk/Santa-Fe-Hotels-Comfort-Inn-Suites-Los-Alamos.h74653.Hotel-Information) Los Alamos 8.0/10 Very good (581 reviews) "Solid hotel with very friendly and supportive staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Markus £96 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Santa-Fe-Hotels-Comfort-Inn-Suites-Los-Alamos.h74653.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/188d3975.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/c2e38f7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/b013eb88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/8c161554.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Los Alamos White Rock [](https://www.expedia.co.uk/Santa-Fe-Hotels-Hampton-Inn-Suites-Los-Alamos-White-Rock.h908632.Hotel-Information) Los Alamos 9.0/10 Wonderful (682 reviews) "Very friendly staff, nice room, convenient breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenna £95 includes taxes & fees 17 Jan - 18 Jan [](https://www.expedia.co.uk/Santa-Fe-Hotels-Hampton-Inn-Suites-Los-Alamos-White-Rock.h908632.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/ff6e8279.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/2aaff96a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-parking](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/9536bd31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/16200/16124/3a9dbc27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Española [](https://www.expedia.co.uk/Santa-Fe-Hotels-Rodeway-Inn.h16124.Hotel-Information) Espanola 6.2/10 (468 reviews) "Friendly staff, clean on the surface, appears to be in renovation stage, heat and air worked fine, lighted/fenced parking, filthy sheets, cigarette burned bed covers, no (soap, shampoo, conditioner, hair dryer), and breakfast was just coffee and oatmeal packets. This place is perfect as a homeless refuge or a 1 hour rental. Do yourself a favor and stay at one of the local casinos." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) M L £50 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Santa-Fe-Hotels-Rodeway-Inn.h16124.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/1e1b9063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/08467533.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/4c9d463d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/65b278ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Los Alamos Entrada Park by IHG [](https://www.expedia.co.uk/Santa-Fe-Hotels-Holiday-Inn-Express-Hotel-Suites-Los-Alamos.h2976403.Hotel-Information) Los Alamos 8.8/10 Excellent (750 reviews) "Good for overnight stay. Staff was very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittany Nichole £110 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Santa-Fe-Hotels-Holiday-Inn-Express-Hotel-Suites-Los-Alamos.h2976403.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/866ea737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free wired Internet](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/ad784a28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/fa5fca8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking (Multi-level) | Desk, blackout curtains, iron/ironing board, free wired Internet](https://images.trvl-media.com/lodging/2000000/1190000/1184600/1184592/8cabce0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Santa Fe-North [](https://www.expedia.co.uk/Santa-Fe-Hotels-Homewood-Suites-By-Hilton-Santa-Fe-North.h1184592.Hotel-Information) Santa Fe 9.2/10 Wonderful (1,002 reviews) "Overall stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ajit £102 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Santa-Fe-Hotels-Homewood-Suites-By-Hilton-Santa-Fe-North.h1184592.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/c2604840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/ecbc45c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/90618c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/59a04f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Espanola [](https://www.expedia.co.uk/Santa-Fe-Hotels-Days-Inn-By-Wyndham-Espanola.h19678.Hotel-Information) Espanola 5.8/10 (587 reviews) "Good place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sergio £78 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Santa-Fe-Hotels-Days-Inn-By-Wyndham-Espanola.h19678.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-25&endDate=2026-01-26®ionId=553248635975872198&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesilla-Hotels.d553248635975872198.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesilla-Hotels.d553248635975872198.Travel-Guide-Hotels) ## Top La Mesilla Hotel Reviews ![Hotel Glorieta](https://images.trvl-media.com/lodging/1000000/10000/3200/3139/912a4f46_y.jpg) ### Hotel Glorieta 10/10 Excellent "Great place! Room and staff were wonderful." [](https://expedia.co.uk/Santa-Fe-Hotels-Hotel-Glorieta.h3139.Hotel-Information) ![Hilton Santa Fe Buffalo Thunder](https://images.trvl-media.com/lodging/3000000/2060000/2059000/2058957/c6ba74ab_y.jpg) ### Hilton Santa Fe Buffalo Thunder 10/10 Excellent "room was clean & quiet, beautiful hotel, beautiful pool & huge hot tub " [](https://expedia.co.uk/Santa-Fe-Hotels-Hilton-Santa-Fe-Buffalo-Thunder.h2058957.Hotel-Information) ![Four Seasons Resort Rancho Encantado Santa Fe](https://images.trvl-media.com/lodging/1000000/50000/40800/40731/eb9982cf_y.jpg) ### Four Seasons Resort Rancho Encantado Santa Fe 10/10 Excellent "Great service and property " [](https://expedia.co.uk/Santa-Fe-Hotels-Four-Seasons-Resort-Rancho-Encantado-Santa-Fe.h40731.Hotel-Information) ![Cities Of Gold Casino](https://images.trvl-media.com/lodging/1000000/130000/120800/120761/4dd42a18_y.jpg) ### Cities Of Gold Casino 10/10 Excellent "Clean rooms, good staff" [](https://expedia.co.uk/Santa-Fe-Hotels-Cities-Of-Gold-Casino.h120761.Hotel-Information) ![Wingate by Wyndham Los Alamos](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/e5b066f8_y.jpg) ### Wingate by Wyndham Los Alamos 10/10 Excellent "Well stocked and clean." [](https://expedia.co.uk/Santa-Fe-Hotels-Comfort-Inn-Suites-Los-Alamos.h74653.Hotel-Information) ![Bishop's Lodge, Auberge Collection](https://images.trvl-media.com/lodging/1000000/50000/40800/40737/dc73db0b_y.jpg) ### Bishop's Lodge, Auberge Collection 10/10 Excellent "Room was spotless, staff were exceptional, the chef was beyond great. Only mi or issue was some of the lighting on some of the paths around the property. " [](https://expedia.co.uk/Santa-Fe-Hotels-Bishops-Lodge.h40737.Hotel-Information) ![Vista La Sierra | Pet Friendly, Mountain View!](https://images.trvl-media.com/lodging/68000000/67630000/67628500/67628492/9945b31a_y.jpg) ### Vista La Sierra | Pet Friendly, Mountain View! 10/10 Excellent "Loved the view! Bed was very comfortable and the home was warm and cozy." [](https://expedia.co.uk/Santa-Fe-Hotels-Vista-La-Sierra-Pet-Friendly.h67628492.Hotel-Information) ![Casa Escondida Bed & Breakfast](https://images.trvl-media.com/lodging/1000000/530000/521400/521375/a25f16f6_y.jpg) ### Casa Escondida Bed & Breakfast 10/10 Excellent "This was our first Bed & Breakfast and let me tell you it did not disappoint. We cannot say enough great things about our experience. The staff was kind and had great suggestions on what to do while in town. The food was excellent, the property was quaint and full of character. We cannot wait to come back and visit. " [](https://expedia.co.uk/Santa-Fe-Hotels-Casa-Escondida-Bed-Breakfast.h521375.Hotel-Information) ![Motel 6 Espanola, NM](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/96f30ddd_y.jpg) ### Motel 6 Espanola, NM 10/10 Excellent "One of the better hotels I have stayed in." [](https://expedia.co.uk/Santa-Fe-Hotels-Motel-6-Espanola.h459557.Hotel-Information) ## More cheap stays in La Mesilla ![Days Inn by Wyndham Espanola](https://images.trvl-media.com/lodging/1000000/20000/19700/19678/c2604840_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Espanola 807 S Riverside Dr Espanola NM £78 8 Feb - 9 Feb includes taxes & fees 5.6/10 (586 reviews) [](https://expedia.co.uk/Santa-Fe-Hotels-Days-Inn-By-Wyndham-Espanola.h19678.Hotel-Information) ![Motel 6 Espanola, NM](https://images.trvl-media.com/lodging/1000000/460000/459600/459557/96f30ddd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 Espanola, NM 811 S Riverside Drive Espanola NM £84 12 Jan - 13 Jan includes taxes & fees 6.4/10 (518 reviews) [](https://expedia.co.uk/Santa-Fe-Hotels-Motel-6-Espanola.h459557.Hotel-Information) ![Hampton Inn & Suites Los Alamos White Rock](https://images.trvl-media.com/lodging/1000000/910000/908700/908632/4901e7b8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn & Suites Los Alamos White Rock 124 State Hwy 4 Los Alamos NM £95 17 Jan - 18 Jan includes taxes & fees 9/10 Wonderful! (682 reviews) [](https://expedia.co.uk/Santa-Fe-Hotels-Hampton-Inn-Suites-Los-Alamos-White-Rock.h908632.Hotel-Information) ![Wingate by Wyndham Los Alamos](https://images.trvl-media.com/lodging/1000000/80000/74700/74653/e5b066f8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Wingate by Wyndham Los Alamos 2455 Trinity Dr Los Alamos NM £96 1 Feb - 2 Feb includes taxes & fees 8/10 Very Good! (578 reviews) [](https://expedia.co.uk/Santa-Fe-Hotels-Comfort-Inn-Suites-Los-Alamos.h74653.Hotel-Information) ![Holiday Inn Express & Suites Los Alamos Entrada Park by IHG](https://images.trvl-media.com/lodging/3000000/2980000/2976500/2976403/65b278ef_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Los Alamos Entrada Park by IHG 60 Entrada Dr Los Alamos NM £110 1 Feb - 2 Feb includes taxes & fees 8.8/10 Excellent! (747 reviews) [](https://expedia.co.uk/Santa-Fe-Hotels-Holiday-Inn-Express-Hotel-Suites-Los-Alamos.h2976403.Hotel-Information) ![Ohkay Casino Resort Hotel](https://images.trvl-media.com/lodging/1000000/460000/458100/458023/5368dc35_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Ohkay Casino Resort Hotel Highway 68 Ohkay Owingeh NM [Get rates](https://expedia.co.uk/Hotel-Search?startDate=25%2F01%2F2026&endDate=26%2F01%2F2026&selected=458023&PinnedHotelID=458023&HadPinnedHotel=true®ionId=553248635975872198) 7.8/10 Good! (791 reviews) [](https://expedia.co.uk/Santa-Fe-Hotels-Ohkay-Casino-Resort-Hotel.h458023.Hotel-Information) ## Frequently asked questions ### What's the best place for a stay in La Mesilla? ### What are some of the best holiday rentals that La Mesilla has to offer? ### If I need to cancel my hotel reservation in La Mesilla, will I receive a refund? ### What is staying in La Mesilla like? ### What should I see while I'm in La Mesilla? ### What's the weather like in La Mesilla? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Alcalde Hotels ](https://www.expedia.co.uk/Alcalde-Hotels.d3000421609.Travel-Guide-Hotels) - [Chimayo Hotels ](https://www.expedia.co.uk/Chimayo-Hotels.d89282.Travel-Guide-Hotels) - [Cordova Hotels ](https://www.expedia.co.uk/Cordova-Hotels.d553248635975847996.Travel-Guide-Hotels) - [Cuyamungue Hotels ](https://www.expedia.co.uk/Cuyamungue-Hotels.d6294902.Travel-Guide-Hotels) - [Los Alamos County Hotels ](https://www.expedia.co.uk/Destinations-In-Los-Alamos-County.d553248635976434081.Hotel-Destinations) - 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