Title: TOP Adults Only Resorts & Hotels in Key West Historic District, FL for 2026 | Expedia.co.uk [Key West Historic District Travel Guide](https://expedia.co.uk/Key-West-Key-West-Historic-District.dx6281809)[Flights to Key West](https://expedia.co.uk/Cheap-Flights-To-Key-West.d1187.Travel-Guide-Flights)[Things to do in Key West](https://expedia.co.uk/Things-To-Do-In-Key-West.d1187.Travel-Guide-Activities)[Key West Historic District Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Key-West-Historic-District.d6281809.Car-Hire-Guide)[Key West Historic District Holidays](https://expedia.co.uk/Key-West-Historic-District.d6281809.Holidays-City-Breaks) ![Audubon House and Tropical Gardens featuring a house](https://images.trvl-media.com/place/6068599/e22dc889-0174-435e-9d9b-302d362fd045.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6068599/e22dc889-0174-435e-9d9b-302d362fd045.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Key West Historic District Adults Only Resorts & Hotels Tonight [23 Jan - 24 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6281809&startDate=2026-01-23&endDate=2026-01-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [24 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6281809&startDate=2026-01-24&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) This weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6281809&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [30 Jan - 1 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6281809&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Our top choices for Key West Historic District adults-only hotels ![Outdoor spa tub](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/77f11bb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/8af6b0ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Room | Courtyard view](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/0849ca06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![NYAH Private Balcony Room 6 Single Beds | Balcony view](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/a350e3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NYAH Key West - Adults Only [](https://www.expedia.co.uk/Key-West-Hotels-NYAH-Key-West-Adults-Only.h7500588.Hotel-Information) Key West Historic District 8.0/10 Very good (1,016 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Venkata Durga Phanindra Reddy [](https://www.expedia.co.uk/Key-West-Hotels-NYAH-Key-West-Adults-Only.h7500588.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/9ce49b35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/d8706fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/1fc21e10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Duval Duplex 2 bedrooms 25 ft Balcony (Adults Only) | Living area | 43-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/83acfbb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Duval House [](https://www.expedia.co.uk/Key-West-Hotels-Duval-House.h900423.Hotel-Information) Old Town Key West 9.4/10 Exceptional (1,005 reviews) "Great place! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £292 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Key-West-Hotels-Duval-House.h900423.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/58000000/57740000/57737100/57737072/011feea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/58000000/57740000/57737100/57737072/530c52f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/58000000/57740000/57737100/57737072/a706ca4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/58000000/57740000/57737100/57737072/99da8b8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### FLOR DE CANA \~ Adults Only, Queen Room w/Pool View at Azul Mansion! [](https://www.expedia.co.uk/Key-West-Hotels-FLOR-DE-CANA-Adults-Only.h57737072.Hotel-Information) Old Town Key West 9.8/10 Exceptional (147 reviews) "Great property, great location.. close to everything but quiet at night!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) brian s. £252 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Key-West-Hotels-FLOR-DE-CANA-Adults-Only.h57737072.Hotel-Information) ![Queen Deluxe ADA | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/3d7c7063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/cb58ce3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/37c4e4c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/810000/809100/809031/f9d7e75f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Almond Tree Inn Hotel - Adults Only [](https://www.expedia.co.uk/Key-West-Hotels-Almond-Tree-Inn.h809031.Hotel-Information) Old Town Key West 10/10 Exceptional (1,004 reviews) "Clean room , friendly staff , excellent location . Would stay again ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleen £335 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Key-West-Hotels-Almond-Tree-Inn.h809031.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/890000/889900/889862/d2b2f582.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/1000000/890000/889900/889862/12655222.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![American cuisine](https://images.trvl-media.com/lodging/1000000/890000/889900/889862/528c228e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools](https://images.trvl-media.com/lodging/1000000/890000/889900/889862/0c033c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marquesa Hotel [](https://www.expedia.co.uk/Key-West-Hotels-The-Marquesa-Hotel.h889862.Hotel-Information) Old Town Key West 9.8/10 Exceptional (1,001 reviews) "Perfect place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Paulette £405 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Key-West-Hotels-The-Marquesa-Hotel.h889862.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/adc3a7f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/8cdae276.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/cfae758a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun deck](https://images.trvl-media.com/lodging/1000000/810000/809100/809032/a23eab61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Orchid Key Inn - Adults Only [](https://www.expedia.co.uk/Key-West-Hotels-Orchid-Key-Inn.h809032.Hotel-Information) Old Town Key West 9.8/10 Exceptional (1,003 reviews) "Room was great along with the staff. The hotel is in a great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £332 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Key-West-Hotels-Orchid-Key-Inn.h809032.Hotel-Information) ![Porch](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/3e2c6b2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/c435c8cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/6eb12223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/e213aee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heron House - Adult Only [](https://www.expedia.co.uk/Key-West-Hotels-Heron-House-Adult-Only.h57730.Hotel-Information) Old Town Key West 9.0/10 Wonderful (1,146 reviews) "Loved our stay here! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brianna £290 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Key-West-Hotels-Heron-House-Adult-Only.h57730.Hotel-Information) ![Building design](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/a8250942.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/f1874592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/f4becc1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed (ADULT ONLY) | Individually decorated, individually furnished, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/ee1be58b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Southernmost Inn - Adults Only [](https://www.expedia.co.uk/Key-West-Hotels-The-Southernmost-Inn-Adults-Only.h4280752.Hotel-Information) Old Town Key West 8.2/10 Very good (1,255 reviews) "Great service very nice rooms will go again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £305 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Key-West-Hotels-The-Southernmost-Inn-Adults-Only.h4280752.Hotel-Information) ![A heated pool](https://images.trvl-media.com/lodging/84000000/83540000/83530100/83530033/199ed2a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach nearby](https://images.trvl-media.com/lodging/84000000/83540000/83530100/83530033/533d2978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/84000000/83540000/83530100/83530033/9ce2fe64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/84000000/83540000/83530100/83530033/ed21bff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### KEITT \~ Adult Only, 2nd Floor 1 Bedroom w/ Shared Pool, Scarlet Mango Inn! [](https://www.expedia.co.uk/Key-West-Hotels-KEITT-Adult-Only.h83530033.Hotel-Information) Old Town Key West 10/10 Exceptional (80 reviews) "This unit was in a fantastic location to downtown but far enough to be quiet and secluded. The pool was a great amenity on hot days and the room was clean and bed was comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Russ J. £289 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Key-West-Hotels-KEITT-Adult-Only.h83530033.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/10000000/9020000/9013900/9013816/3120319b_edited_07ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Room, 1 Queen Bed | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9020000/9013900/9013816/5c65acfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed | Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/10000000/9020000/9013900/9013816/1908c7f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed | Bathroom sink](https://images.trvl-media.com/lodging/10000000/9020000/9013900/9013816/634733ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### L'Habitation Guest House [](https://www.expedia.co.uk/Key-West-Hotels-LHabitation-Guest-House.h9013816.Hotel-Information) Key West Historic District 9.4/10 Exceptional (934 reviews) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott £262 includes taxes & fees 26 Jan - 27 Jan [](https://www.expedia.co.uk/Key-West-Hotels-LHabitation-Guest-House.h9013816.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-06&endDate=2026-02-07®ionId=6281809&adults=2&travelerType=adults_only&sort=RECOMMENDED&openPlayBack=true) ## Top Key West Historic District Hotel Reviews ![Southernmost Beach Resort and Guesthouses](https://images.trvl-media.com/lodging/1000000/870000/863400/863329/026f10af_y.jpg) ### Southernmost Beach Resort and Guesthouses 10/10 Excellent "Great place to stay" [](https://expedia.co.uk/Key-West-Hotels-Southernmost-Beach-Resort.h863329.Hotel-Information) ![Pier House Resort & Spa](https://images.trvl-media.com/lodging/1000000/20000/19400/19307/c9267f77_y.jpg) ### Pier House Resort & Spa 10/10 Excellent "Clean room, and amenities" [](https://expedia.co.uk/Key-West-Hotels-Pier-House-Resort-Spa.h19307.Hotel-Information) ![Heron House Court - Adult Only](https://images.trvl-media.com/lodging/1000000/910000/902100/902014/4d24feec_y.jpg) ### Heron House Court - Adult Only 10/10 Excellent "I would say the staff was excellent. The bed was the best and other than being beat up a little bit being an older building always wonderful" [](https://expedia.co.uk/Key-West-Hotels-Heron-House-Court-Adult-Only.h902014.Hotel-Information) ![Heron House - Adult Only](https://images.trvl-media.com/lodging/1000000/60000/57800/57730/04396af1_y.jpg) ### Heron House - Adult Only 10/10 Excellent "We loved everything about our stay. " [](https://expedia.co.uk/Key-West-Hotels-Heron-House-Adult-Only.h57730.Hotel-Information) ![NYAH Key West - Adults Only](https://images.trvl-media.com/lodging/8000000/7510000/7500600/7500588/77f11bb4_y.jpg) ### NYAH Key West - Adults Only 10/10 Excellent "Awesome" [](https://expedia.co.uk/Key-West-Hotels-NYAH-Key-West-Adults-Only.h7500588.Hotel-Information) ![Casa Marina Key West, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/12400/12346/be8c9450_y.jpg) ### Casa Marina Key West, Curio Collection by Hilton 10/10 Excellent "Friendly staff!" [](https://expedia.co.uk/Key-West-Hotels-Casa-Marina-Key-West.h12346.Hotel-Information) ![Duval House](https://images.trvl-media.com/lodging/1000000/910000/900500/900423/d8706fe9_y.jpg) ### Duval House 10/10 Excellent "Yes" [](https://expedia.co.uk/Key-West-Hotels-Duval-House.h900423.Hotel-Information) ![The Marker Key West Harbor Resort](https://images.trvl-media.com/lodging/10000000/9150000/9148400/9148379/15d13ee3_y.jpg) ### The Marker Key West Harbor Resort 10/10 Excellent "Very nice hotel and good location. The room was a nice size and clean. Pools and pool bar are nice. Live music at the pool was fun/cool. The food is very average." [](https://expedia.co.uk/Key-West-Hotels-The-Marker-Key-West-Harbor-Resort.h9148379.Hotel-Information) ![The Southernmost Inn - Adults Only](https://images.trvl-media.com/lodging/5000000/4290000/4280800/4280752/2b7e8bad_y.jpg) ### The Southernmost Inn - Adults Only 10/10 Excellent "all good here" [](https://expedia.co.uk/Key-West-Hotels-The-Southernmost-Inn-Adults-Only.h4280752.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [3 Star Hotels in Key West ](https://www.expedia.co.uk/3Star-Key-West-Hotels.s30-0-d1187.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Key West ](https://www.expedia.co.uk/4Star-Key-West-Hotels.s40-0-d1187.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Key West ](https://www.expedia.co.uk/5Star-Key-West-Hotels.s50-0-d1187.Travel-Guide-Filter-Hotels) - [Bahama Village Hotels ](https://www.expedia.co.uk/Bahama-Village-Key-West-Hotels.0-n553248621533115696-0.Travel-Guide-Filter-Hotels) - [Hotels near Clarence S. 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