Title: TOP Luxury Hotels in Greenville - Spartanburg, SC for 2026 - Greenville - Spartanburg Upscale Hotels | Expedia.co.uk [Greenville - Spartanburg Travel Guide](https://expedia.co.uk/Greenville-Spartanburg.dx6035267)[Hotels in Greenville - Spartanburg](https://expedia.co.uk/Greenville-Spartanburg-Hotels.d6035267.Travel-Guide-Hotels)[Holiday Rentals in Greenville - Spartanburg](https://expedia.co.uk/Greenville-Spartanburg-Holiday-Rentals.d6035267.Travel-Guide-HolidayRentals)[Flights to Greenville - Spartanburg](https://expedia.co.uk/Cheap-Flights-To-Greenville-Spartanburg.d6035267.Travel-Guide-Flights)[Things to do in Greenville - Spartanburg](https://expedia.co.uk/Things-To-Do-In-Greenville-Spartanburg.d6035267.Travel-Guide-Activities)[Greenville - Spartanburg Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Greenville-Spartanburg.d6035267.Car-Hire-Guide)[Greenville - Spartanburg Holidays](https://expedia.co.uk/Greenville-Spartanburg.d6035267.Holidays-City-Breaks) ![Greenville - Spartanburg featuring landscape views, religious aspects and views](https://images.trvl-media.com/place/6035267/f9a1c090-d6c5-46f5-b727-1be5c766cfdb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina ![](https://images.trvl-media.com/place/6035267/f9a1c090-d6c5-46f5-b727-1be5c766cfdb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greenville - Spartanburg Luxury Hotels Tonight [12 Mar - 13 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6035267&startDate=2026-03-12&endDate=2026-03-13&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [13 Mar - 14 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6035267&startDate=2026-03-13&endDate=2026-03-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6035267&startDate=2026-03-13&endDate=2026-03-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [20 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6035267&startDate=2026-03-20&endDate=2026-03-22&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Greenville - Spartanburg luxury hotels ![Exterior](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/a7016c90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/w3997h2667x0y0-c3100c19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grand Bohemian Lodge Greenville, Autograph Collection [](https://www.expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) Greenville Downtown 9.6/10 Exceptional (461 reviews) "The room was very clean, the food amazing, and the staff was efficient and friendly.Will definitely be back." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharlene £243 includes taxes & fees 17 Mar - 18 Mar [](https://www.expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/a0f70343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/93cc35df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/e5bdee00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/85a8d167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Poinsett Greenville [](https://www.expedia.co.uk/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (1,002 reviews) "Great hotel Great location Great room Friendly and courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £155 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/91df3d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/32050804.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), body treatments, body wraps, body scrubs](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/4bf90c6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89690000/89689300/89689223/d2844575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Hartness [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) Greenville 9.8/10 Exceptional (672 reviews) "The hotel was clean staff was amazing room was outstanding." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Clifford £143 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Greenville-Hotels-Hotel-Hartness.h89689223.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/5d8afb5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/11616a20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/6a340cc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/17500/17483/158027e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Greenville Marriott [](https://www.expedia.co.uk/Greenville-Hotels-Greenville-Marriott.h17483.Hotel-Information) Greenville 8.6/10 Excellent (630 reviews) "Stay here often. Always great service. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrea £97 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Greenville-Hotels-Greenville-Marriott.h17483.Hotel-Information) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/5e1376bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![One Bedroom (Self Check-in with Virtual Front Desk) | Laptop workspace, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/21618793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Living area | 55-inch flat-screen TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/fb93f07a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Two Bedroom (Self Check-in with Virtual Front Desk) | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38600000/38593300/38593248/3786343d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mint House Greenville Downtown by Kasa [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) Greenville Downtown 9.2/10 Wonderful (797 reviews) "Spotless wonderful stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tanganica £77 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Greenville-Spartanburg-Hotels-Mint-House-Downtown-Greenville.h38593248.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/96abb166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/1f0407e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/b8d82b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) Travelers Rest 9.8/10 Exceptional (31 reviews) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck £344 includes taxes & fees 19 Mar - 20 Mar [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) ![Trailside Wedge Cottage | Terrace/patio](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/346fcb37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vista Wedge Cottage | Private kitchen | Full-sized fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/9304eefe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Trailside Wedge Cottage | Living area | Smart TV](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/f19cdb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/89000000/88370000/88362000/88361952/87440d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Station by Compo Hotels [](https://www.expedia.co.uk/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) Travelers Rest 10/10 Exceptional (17 reviews) "great place perfect for more privacy vs. a standard hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £229 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Travelers-Rest-Hotels-The-Station-By-Compo-Hotels.h88361952.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/5b31fd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (769 reviews) "Awesome hotel and very convenient for visiting Clemson." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina £289 includes taxes & fees 14 Mar - 15 Mar [](https://www.expedia.co.uk/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/8963c3c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/a5d6b89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.co.uk/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (572 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan [](https://www.expedia.co.uk/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-26&endDate=2026-03-27®ionId=6035267&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6035267) ## Top Greenville - Spartanburg Hotel Reviews ![Comfort Inn Greenville - Haywood Mall](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/840ecd1b_y.jpg) ### Comfort Inn Greenville - Haywood Mall 4/10 Poor "Air conditioning didn’t work Front Desk was rude both morning & night Toilet was running all night & doesn’t flush properly (229) " [](https://expedia.co.uk/Greenville-Hotels-Comfort-Inn-Greenville-Haywood-Mall.h24994.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/f09ffe86_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Like the suite for families. Also like the full breakfast availability. Overall, great value. " [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/605b3e5f_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 6/10 Okay "We arrived at 7:30 pm and our room was not ready until after 8:15pm.We were sent to a room that had not been cleaned. Then, we had to wait 30 mins for the staff to clean our new room. It was a disappointing situation." [](https://expedia.co.uk/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/2e6ff142_y.jpg) ### Hyatt Regency Greenville 8/10 Good "Great location, very nice staff." [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Didn’t get to enjoy the pool." [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Staff was super friendly and accessible. Room was very clean. Breakfast and evening repast was enough to fill you up and was very appetizing. We did not have to spend any money on food outside the hotel so this hotel offers a big bang for your buck. I will be staying at Drury Inn in the future. " [](https://expedia.co.uk/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/8017eeff_y.jpg) ### Hilton Greenville 8/10 Good "Good staff. Older property but maintained reasonably well. Ok location. " [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3840h2556x0y3-09ad394d_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Great staff and very clean. 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