Title: TOP Boutique Hotels in Greenville - Spartanburg, SC for 2026 | Expedia.co.uk [Greenville - Spartanburg Travel Guide](https://expedia.co.uk/Greenville-Spartanburg.dx6035267)[Hotels in Greenville - Spartanburg](https://expedia.co.uk/Greenville-Spartanburg-Hotels.d6035267.Travel-Guide-Hotels)[Holiday Rentals in Greenville - Spartanburg](https://expedia.co.uk/Greenville-Spartanburg-Holiday-Rentals.d6035267.Travel-Guide-HolidayRentals)[Flights to Greenville - Spartanburg](https://expedia.co.uk/Cheap-Flights-To-Greenville-Spartanburg.d6035267.Travel-Guide-Flights)[Things to do in Greenville - Spartanburg](https://expedia.co.uk/Things-To-Do-In-Greenville-Spartanburg.d6035267.Travel-Guide-Activities)[Greenville - Spartanburg Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Greenville-Spartanburg.d6035267.Car-Hire-Guide)[Greenville - Spartanburg Holidays](https://expedia.co.uk/Greenville-Spartanburg.d6035267.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/6035267/f9a1c090-d6c5-46f5-b727-1be5c766cfdb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina ![](https://images.trvl-media.com/place/6035267/f9a1c090-d6c5-46f5-b727-1be5c766cfdb.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greenville - Spartanburg Boutique Hotels Tonight [27 Mar - 28 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6035267&startDate=2026-03-27&endDate=2026-03-28&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [28 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6035267&startDate=2026-03-28&endDate=2026-03-29&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6035267&startDate=2026-03-27&endDate=2026-03-29&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6035267&startDate=2026-04-03&endDate=2026-04-05&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Greenville - Spartanburg boutique hotels ![Courtyard](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/96abb166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/53680281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/598f5b2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/10000000/9710000/9704700/9704647/b8d82b26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Domestique [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) Travelers Rest 9.8/10 Exceptional (33 reviews) "Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chuck £395 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Hotel-Domestique.h9704647.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-10&endDate=2026-04-11®ionId=6035267&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ## Top Greenville - Spartanburg Hotel Reviews ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3840h2556x0y3-09ad394d_y.jpg) ### Hyatt Place Greenville/Haywood 6/10 Okay "My only complaint was really the noise and not as clean as I would have expected it to be, air conditioning unit was not very powerful and made it very stuffy and no air circulation so it kind of smelled funky, but overall it was a good stay " [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [4 Star Hotels in Greenville ](https://www.expedia.co.uk/4Star-Greenville-Hotels.s40-0-d1388.Travel-Guide-Filter-Hotels) - 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