
Search Business Hotels in Florida Panhandle
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Florida Panhandle Business Hotels
Our top choices for Florida Panhandle business-friendly hotels

Holiday Inn Express Tallahassee - I-10 E by IHG
Holiday Inn Express Tallahassee - I-10 E by IHGMarket District
8.2 out of 10, Very good, (1,006 reviews)
The price is £78
includes taxes & fees
26 Apr - 27 Apr

9.2 out of 10, Wonderful, (1,347 reviews)
The price is £80
includes taxes & fees
23 Apr - 24 Apr
The price is £129
includes taxes & fees
26 Apr - 27 Apr

9.0 out of 10, Wonderful, (2,094 reviews)
The price is £60
includes taxes & fees
23 Apr - 24 Apr

9.0 out of 10, Wonderful, (1,000 reviews)
The price is £88
includes taxes & fees
26 Apr - 27 Apr

9.4 out of 10, Exceptional, (1,750 reviews)
The price is £126
includes taxes & fees
12 Apr - 13 Apr

9.8 out of 10, Exceptional, (1,628 reviews)
The price is £109
includes taxes & fees
26 Apr - 27 Apr

Sleep Inn & Suites Defuniak Springs - Crestview
Sleep Inn & Suites Defuniak Springs - CrestviewDe Funiak Springs
9.2 out of 10, Wonderful, (1,003 reviews)
The price is £69
includes taxes & fees
30 Apr - 1 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Florida Panhandle Hotel Reviews

The Henderson Beach Resort & Spa
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- 4 Star Hotels in Mexico Beach
- 5 Star Hotels in Mexico Beach
- Alford Hotels
- Altha Hotels
- Adults Only Resorts & in Apalachicola
- Beach Resorts & in Apalachicola
- Blountstown Hotels
- Bristol Hotels
- Callaway Hotels
- Chattahoochee Hotels
- Luxury Hotels in Dog Island
- Fountain Hotels
- Greensboro Hotels
- Gay-Friendly Hotels in Highland City
- Hosford Hotels
- Hotels with Laundry Service in Marianna
- Adults Only Resorts & in Mexico Beach
- Beach Resorts & in Mexico Beach
- Cheap Hotels in Mexico Beach
- Hotels with Parking in Mexico Beach
- Hotels with Hot Tubs in Mexico Beach
- Hotels with Pool in Mexico Beach
- Pet-Friendly Hotels in Mexico Beach
- Ski Hotels in Mexico Beach
- Wedding Hotels in Mexico Beach
- Mexico Beach Hotels
- Town Houses in Mexico Beach
- Resorts in North West Florida
- Aimbridge Hospitality Hotels in North West Florida
- Beach Resorts & in North West Florida
- Hilton Hotels in North West Florida
- La Quinta Inn & Suites Hotels in North West Florida
- North West Florida Hotels
- Motels in North West Florida
- Adults Only Resorts & in Panama City
- Beach Resorts & in Panama City
- Cheap Hotels in Panama City
- Gay-Friendly Hotels in Panama City
- Hotels with Early Check-in in Panama City
- Hotels with Balcony in Panama City
- Hotels with Indoor Pools in Panama City
- Beach Resorts & in Port St. Joe
- Wyndham Hotels in Port St. Joe
- Port St. Joe Hotels
- Quincy Hotels
- Beach Resorts & in Shell Island
- Cheap Hotels in Shell Island
- Cheap Hotels in Shell Island
- Family-Friendly Hotels in Shell Island
- Hotels with a Bar in Shell Island
- Pet-Friendly Hotels in Shell Island
- Wedding Hotels in Shell Island
- Sopchoppy Hotels
- Springfield Hotels
- Sumatra Hotels
- Hotels near Three Rivers State Park
- Hotels near Torreya State Park
- Waterside Village Hotels
- Wewahitchka Hotels
- Youngstown Hotels
- Ace Australia Rental Cars in Mexico Beach
- Centauro Rental Cars in Mexico Beach
- Click & Rent Rental Cars in Mexico Beach
- Enterprise Rental Cars in Bristol
- Europcar Rental Cars in Mexico Beach
- Firefly Rental Cars in Mexico Beach
- Greenmotion Rental Cars in Wewahitchka
- Guerin Rental Cars in Mexico Beach
- Luxury Car Hire in North West Florida
- Midsize Car Hire in North West Florida
- Mini Car Hire in Mexico Beach
- Minivan Car Hire in Mexico Beach
- Nü Car Rentals Rental Cars in Mexico Beach
- Ok Mobility Rental Cars in North West Florida
- Offer Car Hire Rental Cars in North West Florida








































