Title: Hotels in Depew, NY - Best Depew Hotels from £51 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Depew](https://expedia.co.uk/Depew-Holiday-Rentals.d6338362.Travel-Guide-HolidayRentals)[Depew Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Depew.d6338362.Car-Hire-Guide)[Depew Holidays](https://expedia.co.uk/Depew.d6338362.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Depew, NY from £51 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Depew Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Depew%2C+New+York%2C+United+States+of+America®ionId=6338362&latLong=42.900423%2C-78.70494&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&lodging=APART_HOTEL) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Depew%2C+New+York%2C+United+States+of+America®ionId=6338362&latLong=42.900423%2C-78.70494&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&amenities=POOL) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Depew%2C+New+York%2C+United+States+of+America®ionId=6338362&latLong=42.900423%2C-78.70494&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&amenities=HOT_TUB) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Depew%2C+New+York%2C+United+States+of+America®ionId=6338362&latLong=42.900423%2C-78.70494&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&lodging=APARTMENT) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Depew%2C+New+York%2C+United+States+of+America®ionId=6338362&latLong=42.900423%2C-78.70494&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Depew%2C+New+York%2C+United+States+of+America®ionId=6338362&latLong=42.900423%2C-78.70494&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&amenities=PETS) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Depew%2C+New+York%2C+United+States+of+America®ionId=6338362&latLong=42.900423%2C-78.70494&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&lodging=CONDO) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Depew%2C+New+York%2C+United+States+of+America®ionId=6338362&latLong=42.900423%2C-78.70494&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&lodging=COTTAGE) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Depew%2C+New+York%2C+United+States+of+America®ionId=6338362&latLong=42.900423%2C-78.70494&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&amenities=WATER_PARK) ## Check prices for these dates Tonight [23 Dec - 24 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6338362&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [24 Dec - 25 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6338362&startDate=2025-12-24&endDate=2025-12-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6338362&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6338362&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Depew hotels ![Lobby lounge](https://images.trvl-media.com/lodging/21000000/20010000/20009600/20009524/607a1b17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/21000000/20010000/20009600/20009524/90e107fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/21000000/20010000/20009600/20009524/1606524c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/21000000/20010000/20009600/20009524/80b636a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Niagara Falls Blvd USA [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Comfort-Inn-Suites-Niagara-Falls-Blvd-USA.h20009524.Hotel-Information) La Salle 8.8/10 Excellent (1401) "Had a very nice stay! Would stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matt £64 includes taxes & fees 9 Jan - 10 Jan 2026 [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Comfort-Inn-Suites-Niagara-Falls-Blvd-USA.h20009524.Hotel-Information) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/ee46454f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/1edd14d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/328c49a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/980000/973800/973773/95428045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG [](https://www.expedia.co.uk/Buffalo-Hotels-Holiday-Inn-Express-Hotel-Suites-Buffalo-Airport.h973773.Hotel-Information) Buffalo 8.2/10 Very good (1005) Located just minutes from Buffalo Niagara International Airport, this hotel offers a refreshing indoor pool and fitness centre. Enjoy free breakfast and WiFi before exploring nearby Walden Galleria Mall or catching the free airport shuttle. --- "The staff were exceptional, the room was beautiful and clean, the location couldn’t be beat and it was in our price range!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jen £84 includes taxes & fees 6 Jan - 7 Jan 2026 [](https://www.expedia.co.uk/Buffalo-Hotels-Holiday-Inn-Express-Hotel-Suites-Buffalo-Airport.h973773.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/9d03cce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/d35175de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/77375700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Buffalo Airport [](https://www.expedia.co.uk/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) Buffalo 8.0/10 Very good (1906) Just 1.1 mi from Buffalo Airport with free 24-hour shuttle, this hotel offers hiking trails and kayaking options nearby. Enjoy free breakfast, WiFi, parking, and easy access to Walden Galleria Mall and University At Buffalo. --- "Room was very clean and front desk staff was super friendly. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Winsome £60 includes taxes & fees 15 Jan - 16 Jan 2026 [](https://www.expedia.co.uk/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) ![Lunch and dinner served, American cuisine](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/19bd0f50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/12050768.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed with Sofa bed | In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/52bfdeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/e6ba9cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Buffalo Airport Hotel [](https://www.expedia.co.uk/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) Buffalo 8.0/10 Very good (2799) Just 1 mile from the airport with 24-hour free shuttle, this quiet retreat features Sports 365 Bar & Grill serving American cuisine. Travellers love the helpful staff, free WiFi, parking, and proximity to dining options and Walden Galleria Mall. --- "Perfect for staying overnight !! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorena £56 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/41f0c04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/655c2793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/3a4ccacd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 9:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/3ddda5b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Buffalo - Amherst, NY [](https://www.expedia.co.uk/Buffalo-Hotels-Hampton-Inn-Buffalo-Amherst.h50706489.Hotel-Information) Buffalo 9.4/10 Exceptional (1993) Comfortable beds await at this friendly Buffalo hotel with indoor pool and 24-hour fitness centre. Located near Walden Galleria Mall and Northtown Centre, guests love the complimentary breakfast. Buffalo Niagara International Airport is just 20 minutes away. --- "Great room, staff, breakfast, and pool- would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Madison £89 includes taxes & fees 6 Jan - 7 Jan 2026 [](https://www.expedia.co.uk/Buffalo-Hotels-Hampton-Inn-Buffalo-Amherst.h50706489.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/6499bfe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/06f2a4f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/456d3072.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 2 Queen Beds, Non Smoking | Premium bedding, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/25000000/24730000/24723600/24723591/f96730ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Buffalo Amherst [](https://www.expedia.co.uk/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information) Buffalo 8.4/10 Very good (1970) Experience relaxing accommodation just minutes from University at Buffalo and Boulevard Place. This hotel offers an indoor pool, fitness centre, and complimentary breakfast, WiFi, and parking. Guests consistently praise the comfortable beds and attentive staff. --- "The hotel was great clean, accesable. quiet, close to UB" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bruce £67 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/Buffalo-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Buffalo-Amherst.h24723591.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/17000000/16350000/16348700/16348639/b9a48adb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16350000/16348700/16348639/159c1ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/17000000/16350000/16348700/16348639/6b76ab78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/17000000/16350000/16348700/16348639/4e0e9043.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Niagara Falls [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Microtel-Inn-Suites-By-Wyndham-Niagara-Falls.h16348639.Hotel-Information) Niagara Falls 8.2/10 Very good (1005) This hotel offers free breakfast, WiFi, and parking, with a 24-hour fitness centre for active travellers. Just a short drive from Niagara Falls State Park and Fashion Outlets, it's also near Clifton Hill and the casino. --- "The staff friendly and the room was very clean and comfortable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lin £61 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Microtel-Inn-Suites-By-Wyndham-Niagara-Falls.h16348639.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/10000/900/816/f798ced4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Double Beds (Smoke Free) | 1 bedroom, desk, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/900/816/d6d95409.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/900/816/56cc9184.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/10000/900/816/cbd00f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Buffalo - Niagara Airport [](https://www.expedia.co.uk/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) Bowmansville 7.2/10 Good (1003) Peaceful retreat just 15 minutes from University At Buffalo and Walden Galleria Mall. Free WiFi and parking make travel simple, while the 24-hour front desk ensures assistance anytime. Located near restaurants and shopping, with Buffalo Airport only 11 minutes away. --- "Loved every moment, clean, well affordable and the staff were amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joselyin £46 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Buffalo-Hotels-Red-Roof-Inn-Buffalo-Niagara-Airport.h816.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/139ee991.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/a196e14b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 6:30 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/b33f35a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/295249d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Near Walden Galleria Mall [](https://www.expedia.co.uk/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) Buffalo 8.0/10 Very good (1001) "Friendly staff, easy parking" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittany £64 includes taxes & fees 12 Jan - 13 Jan 2026 [](https://www.expedia.co.uk/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) ![Standard Room, 1 King Bed, Non Smoking (Ground Floor, Pets Allowed) | 1 bedroom, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/fc11b7d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/a26a08df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/0cf000f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2071/b47b27ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Darien Lakes [](https://www.expedia.co.uk/Corfu-Hotels-Econo-Lodge-Darien-Lakes.h2071.Hotel-Information) Corfu 7.8/10 Good (804) This business-friendly hotel offers free WiFi and parking, plus a fitness centre for active travellers. Enjoy nearby hiking trails and snowmobiling adventures, with Akron Falls Park in the vicinity. Clean rooms and helpful staff ensure a comfortable stay. --- "Staff was really friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stephen £56 includes taxes & fees 6 Jan - 7 Jan 2026 [](https://www.expedia.co.uk/Corfu-Hotels-Econo-Lodge-Darien-Lakes.h2071.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/15100/15046/ceafd14d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Blackout curtains, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/15100/15046/w5755h3840x5y0-539c4305.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/20000/15100/15046/8a313254.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15100/15046/3cd31e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Lockport [](https://www.expedia.co.uk/Lockport-Hotels-Lockport-Hotel.h15046.Hotel-Information) Lockport 7.4/10 Good (73) Discover tranquility at this quiet Lockport hotel offering free continental breakfast, WiFi, and parking. Work out in the fitness centre before exploring nearby attractions like Four Seasons Players and Big Bridge. Guests consistently praise the helpful staff and clean rooms. --- "Great stay, thanks!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Shirmilla £54 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/Lockport-Hotels-Lockport-Hotel.h15046.Hotel-Information) ![Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/50c6a12d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/3274a349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/ea0d463b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/2685a465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Grand Island - Niagara Falls by IHG [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) Grand Island 8.8/10 Excellent (1623) "Clean room, amazing staff, good amenities.. Really enjoyed our family stay there..!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Sriprakash £63 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/a429a676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/dbce5670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/ae2b2f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/126900/126836/6c12c2ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn Amherst - Buffalo North near University [](https://www.expedia.co.uk/Buffalo-Hotels-Sleep-Inn.h126836.Hotel-Information) Buffalo 8.8/10 Excellent (1134) Located minutes from University at Buffalo North Campus, this hotel offers a peaceful stay with indoor pool and relaxing hot tub. Guests love the free breakfast, WiFi, parking, and helpful staff. Buffalo Zoo and Walden Galleria Mall are a short drive away. --- "Nicely decorated for the holidays. Very friendly staff, great breakfast and clean comfy room." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen £80 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/Buffalo-Hotels-Sleep-Inn.h126836.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13700/13658/0fdb4d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/20000/13700/13658/1993873a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/20000/13700/13658/19e703a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/13700/13658/57a518f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Buffalo-Airport / Galleria Mall [](https://www.expedia.co.uk/Buffalo-Hotels-Hampton-Inn-Buffalo-Airport-Galleria-Mall.h13658.Hotel-Information) Buffalo 8.6/10 Excellent (1006) Enjoy seamless travel with the complimentary airport shuttle at this Buffalo hotel. Just minutes from Walden Galleria Mall and offering an indoor pool, 24-hour fitness centre, and free breakfast. Guests consistently praise the helpful staff and convenient shopping access. --- "Clean room, friendly staff and great location. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Lisa £90 includes taxes & fees 23 Jan - 24 Jan 2026 [](https://www.expedia.co.uk/Buffalo-Hotels-Hampton-Inn-Buffalo-Airport-Galleria-Mall.h13658.Hotel-Information) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/19000000/18760000/18754400/18754328/04527bd2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/19000000/18760000/18754400/18754328/065e090b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-parking](https://images.trvl-media.com/lodging/19000000/18760000/18754400/18754328/1e669dd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/19000000/18760000/18754400/18754328/e3ae66a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Buffalo-Hamburg [](https://www.expedia.co.uk/Buffalo-Hotels-Hampton-Inn-Buffalo-Hamburg.h18754328.Hotel-Information) Hamburg 9.0/10 Wonderful (1002) Just 10 minutes from Lake Erie and Highmark Stadium, this Hamburg hotel offers a refreshing indoor pool and 24-hour fitness centre. Guests rave about the helpful staff and spotless rooms. Enjoy free breakfast, WiFi, and parking during your stay. --- "Room was very clean and staff friendly" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peter £84 includes taxes & fees 20 Jan - 21 Jan 2026 [](https://www.expedia.co.uk/Buffalo-Hotels-Hampton-Inn-Buffalo-Hamburg.h18754328.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/86fc2ca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/38c1df33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/3f2fe391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/27600/27531/f7f089be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn by Wyndham Buffalo Airport [](https://www.expedia.co.uk/Buffalo-Hotels-La-Quinta-Inn-By-Wyndham-Buffalo-Airport.h27531.Hotel-Information) Buffalo 8.0/10 Very good (1362) Just 2.6 mi from Buffalo Airport with 24-hour free shuttle service. This hotel offers convenient access to Walden Galleria Mall and University At Buffalo - North Campus. Guests love the quiet atmosphere, helpful staff, free breakfast, WiFi and parking. --- "Always clean and friendly!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Stacy £64 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Buffalo-Hotels-La-Quinta-Inn-By-Wyndham-Buffalo-Airport.h27531.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5700/5678/f3251c17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5700/5678/d4ff3d29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/10000/5700/5678/4156f137.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/10000/5700/5678/11c89874.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Buffalo Airport [](https://www.expedia.co.uk/Buffalo-Hotels-Comfort-Inn-Suites.h5678.Hotel-Information) Buffalo 8.2/10 Very good (1270) Experience quiet comfort steps away from Buffalo Niagara Airport with 24-hour shuttle service. The indoor pool offers relaxation after exploring nearby Walden Galleria Mall. Free breakfast, WiFi, and parking add value to this ideally situated hotel. --- "Very nice stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James £83 includes taxes & fees 19 Jan - 20 Jan 2026 [](https://www.expedia.co.uk/Buffalo-Hotels-Comfort-Inn-Suites.h5678.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/1a5b867a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/14d1fc73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/10c75c72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/6000000/5320000/5313700/5313625/93ad4fec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Buffalo South I-90, NY [](https://www.expedia.co.uk/Buffalo-Hotels-Country-Inn-Suites-By-Radisson.h5313625.Hotel-Information) Buffalo 8.2/10 Very good (1292) Situated near Lake Erie, this hotel offers a convenient location with free breakfast, WiFi, and parking. After morning laps in the indoor pool, explore nearby KeyBank Centre or unwind on the terrace. Rooms include refrigerators and microwaves for added comfort. --- "The breakfast was very good for a free hotel breakfast. And the staff was very pleasant. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rhonda £94 includes taxes & fees 12 Jan - 13 Jan 2026 [](https://www.expedia.co.uk/Buffalo-Hotels-Country-Inn-Suites-By-Radisson.h5313625.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/46db5598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/73648063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/1726aaa7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/5200/5183/c135a4a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Summit Inn [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) Niagara Falls 8.6/10 Excellent (1408) "Great breakfast and Very big property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) manoj £68 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Best-Western-Summit-Inn.h5183.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/023ac782.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/1e4370be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking | Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/3d3d0925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/900000/890400/890385/74968bc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge At The Falls North [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Econo-Lodge-At-The-Falls-North.h890385.Hotel-Information) La Salle 7.8/10 Good (1125) Located just a short drive from Niagara Falls State Park, this hotel offers a refreshing outdoor pool and free daily breakfast. Enjoy convenient amenities like WiFi and self parking at no extra cost, plus easy access to Clifton Hill and Fallsview Casino. --- "Staff were very friendly,helpful," ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) john £49 includes taxes & fees 12 Jan - 13 Jan 2026 [](https://www.expedia.co.uk/Niagara-Falls-Hotels-Econo-Lodge-At-The-Falls-North.h890385.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-06&endDate=2026-01-07®ionId=6338362&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Hotels.d6338362.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDepew-Hotels.d6338362.Travel-Guide-Hotels) ## Top Depew Hotel Reviews ![Hyatt Regency Buffalo / Hotel and Conference Center](https://images.trvl-media.com/lodging/1000000/30000/23200/23101/00561234_y.jpg) ### Hyatt Regency Buffalo / Hotel and Conference Center 10/10 Excellent "Clean, amazing staff. Very comfortable. Will visit again. " [](https://expedia.co.uk/Buffalo-Hotels-Hyatt-Regency-Buffalo-Hotel-And-Conference-Center.h23101.Hotel-Information) ![M Hotel Buffalo](https://images.trvl-media.com/lodging/1000000/20000/11300/11231/2c4d5593_y.jpg) ### M Hotel Buffalo 10/10 Excellent "Was a good room and decent stay" [](https://expedia.co.uk/Buffalo-Hotels-Millennium-Buffalo.h11231.Hotel-Information) ![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/90223c0d_y.jpg) ### Buffalo Airport Hotel 10/10 Excellent "Clean room and desk staff was great " [](https://expedia.co.uk/Buffalo-Hotels-Buffalo-Airport-Hotel.h26001.Hotel-Information) ![Hampton Inn Buffalo - Amherst, NY](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/63fc013f_y.jpg) ### Hampton Inn Buffalo - Amherst, NY 10/10 Excellent "Clean, friendly staff, great value." [](https://expedia.co.uk/Buffalo-Hotels-Hampton-Inn-Buffalo-Amherst.h50706489.Hotel-Information) ![Motel 6 Amherst, NY - Buffalo](https://images.trvl-media.com/lodging/1000000/50000/42200/42198/df50dbea_y.jpg) ### Motel 6 Amherst, NY - Buffalo 10/10 Excellent "clean room check in clerk very pleasant " [](https://expedia.co.uk/Buffalo-Hotels-Motel-6-Amherst.h42198.Hotel-Information) ![Hilton Garden Inn Buffalo Airport](https://images.trvl-media.com/lodging/2000000/1350000/1348600/1348597/47d81773_y.jpg) ### Hilton Garden Inn Buffalo Airport 10/10 Excellent "Room was very clean and staff at check in was friendly." [](https://expedia.co.uk/Buffalo-Hotels-Hilton-Garden-Inn-Buffalo-Airport.h1348597.Hotel-Information) ![Garden Place Hotel](https://images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg) ### Garden Place Hotel 10/10 Excellent "Good staff" [](https://expedia.co.uk/Buffalo-Hotels-Garden-Place-Hotel.h1060721.Hotel-Information) ![The Richardson Hotel](https://images.trvl-media.com/lodging/19000000/18140000/18136300/18136290/16863301_y.jpg) ### The Richardson Hotel 10/10 Excellent "Stay at this property every year. Staff was excellent and the property is unique. Highly recommend. " [](https://expedia.co.uk/Buffalo-Hotels-Hotel-Henry-Urban-Resort.h18136290.Hotel-Information) ![Hilton Garden Inn Buffalo Downtown](https://images.trvl-media.com/lodging/9000000/8750000/8745500/8745457/7db896c2_y.jpg) ### Hilton Garden Inn Buffalo Downtown 10/10 Excellent "Clean, spacious room!" [](https://expedia.co.uk/Buffalo-Hotels-Hilton-Garden-Inn-Buffalo-Downtown.h8745457.Hotel-Information) ## More cheap stays in Depew ![CenterWay Hotel Tonawanda](https://images.trvl-media.com/lodging/1000000/80000/76400/76371/66013c67_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### CenterWay Hotel Tonawanda 225 Crestmount Avenue Tonawanda NY £51 29 Dec - 30 Dec includes taxes & fees 7.8/10 Good! (1,001 reviews) [](https://expedia.co.uk/Buffalo-Hotels-CenterWay-Hotel-Tonawanda.h76371.Hotel-Information) ![Sleep Inn & Suites Buffalo Airport](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleep Inn & Suites Buffalo Airport 100 Holtz Dr Buffalo NY £60 15 Jan - 16 Jan 2026 includes taxes & fees 7.8/10 Good! (1,894 reviews) [](https://expedia.co.uk/Buffalo-Hotels-Sleep-Inn-Suites-Buffalo-Airport.h85007.Hotel-Information) ![Holiday Inn Express Grand Island - Niagara Falls by IHG](https://images.trvl-media.com/lodging/19000000/18570000/18567300/18567279/50c6a12d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Grand Island - Niagara Falls by IHG 2761 Long Road Grand Island NY £63 4 Jan - 5 Jan 2026 includes taxes & fees 8.8/10 Excellent! (1,610 reviews) [](https://expedia.co.uk/Niagara-Falls-Hotels-Holiday-Inn-Express-Grand-Island-Niagara-Falls.h18567279.Hotel-Information) ![Quality Inn Near Walden Galleria Mall](https://images.trvl-media.com/lodging/1000000/560000/558600/558591/5207dfe7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn Near Walden Galleria Mall 475 Dingens St Buffalo NY £64 12 Jan - 13 Jan 2026 includes taxes & fees 8/10 Very Good! (1,001 reviews) [](https://expedia.co.uk/Buffalo-Hotels-Quality-Inn-Near-Walden-Galleria-Mall.h558591.Hotel-Information) ![Hampton Inn Buffalo - Amherst, NY](https://images.trvl-media.com/lodging/51000000/50710000/50706500/50706489/63fc013f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn Buffalo - Amherst, NY 1601 Amherst Manor Drive Buffalo NY £89 6 Jan - 7 Jan 2026 includes taxes & fees 9.2/10 Wonderful! (1,992 reviews) [](https://expedia.co.uk/Buffalo-Hotels-Hampton-Inn-Buffalo-Amherst.h50706489.Hotel-Information) ![Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG](https://images.trvl-media.com/lodging/1000000/10000/6300/6258/73c0de62_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG 601 Main St Buffalo NY £102 30 Dec - 31 Dec includes taxes & fees 8.6/10 Excellent! (1,003 reviews) [](https://expedia.co.uk/Buffalo-Hotels-Holiday-Inn-Express-Suites-Buffalo-Downtown-Medical-CTR.h6258.Hotel-Information) ## Frequently asked questions ### When is the best time to go to Depew? > As the peak season runs from February to April, you'll find that Depew becomes a vibrant hub of activity, particularly in the lead-up to spring. This is a fantastic time to engage in sightseeing, with local parks and gardens coming to life. Families and couples alike can enjoy leisurely walks while soaking in the fresh air and natural beauty. > > > April is especially appealing for those who appreciate outdoor dining and community events. Many local eateries begin to open their terraces, allowing you to savour delicious local cuisine while basking in the mild weather. Additionally, this month often features various festivals that celebrate the arrival of spring, providing an excellent opportunity to connect with the local culture. > > > If you're looking for a more budget-friendly option, visiting in December can also be rewarding. It's cooler, the festive atmosphere and holiday lights create a unique charm, superb for those who enjoy seasonal celebrations. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Depew hotel booking with Expedia? ### How much is the nightly rate at a Depew hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - More ways to book - [Allentown Hotels ](https://www.expedia.co.uk/Allentown-Buffalo-Hotels.0-n6338353-0.Travel-Guide-Filter-Hotels) - [Amherst Hotels ](https://www.expedia.co.uk/Amherst-Hotels.d9323.Travel-Guide-Hotels) - [Bowmansville Hotels ](https://www.expedia.co.uk/Bowmansville-Hotels.d7978.Travel-Guide-Hotels) - [Hotels near Buffalo-Exchange Street Station ](https://www.expedia.co.uk/Buffalo-Exchange-Street-Station-Hotels.d6172052.Travel-Guide-Hotels) - [Buffalo Hotels ](https://www.expedia.co.uk/Buffalo-Hotels.d602674.Travel-Guide-Hotels) - [Hotels near Buffalo Niagara Intl. ](https://www.expedia.co.uk/Buffalo-Niagara-Intl-Airport-Hotels.0-aBUF-0.Travel-Guide-Filter-Hotels) - 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