Title: Depew Travel Guide: Best of Depew, Buffalo Travel 2026 | Expedia.co.uk [Hotels in Depew](https://expedia.co.uk/Depew-Hotels.d6338362.Travel-Guide-Hotels)[Holiday Rentals in Depew](https://expedia.co.uk/Depew-Holiday-Rentals.d6338362.Travel-Guide-HolidayRentals)[Depew Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Depew.d6338362.Car-Hire-Guide)[Depew Holidays](https://expedia.co.uk/Depew.d6338362.Holidays-City-Breaks) # Depew Travel Guide ## Tourist Guide ## Visit Depew Things to do ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=DX_SPRING_PROMO_6338362) - Top hotels in Depew - Top Holiday Rentals in Depew ![Buffalo Airport Hotel](https://images.trvl-media.com/lodging/1000000/30000/26100/26001/90223c0d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Buffalo Airport Hotel 4600 Genesee St Buffalo NY £62 17 Feb - 18 Feb includes taxes & fees Stay at this business-friendly hotel in Buffalo. Enjoy free Wi-Fi, free parking and a free airport shuttle. Our guests praise the restaurant and the helpful ... 7.8/10 Good! (2,870 reviews) Comfortable bed and good parking Reviewed on 11 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=17%2F02%2F2026&endDate=18%2F02%2F2026&selected=26001&PinnedHotelID=26001&HadPinnedHotel=true®ionId=6338362) ![Sleep Inn & Suites Buffalo Airport](https://images.trvl-media.com/lodging/1000000/90000/85100/85007/ae021a7d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sleep Inn & Suites Buffalo Airport 100 Holtz Dr Buffalo NY £57 8 Mar - 9 Mar includes taxes & fees Stay at this business-friendly hotel in Buffalo. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ... 7.8/10 Good! (1,986 reviews) Rooms were clean Reviewed on 8 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=85007&PinnedHotelID=85007&HadPinnedHotel=true®ionId=6338362) ![Garden Place Hotel](https://images.trvl-media.com/lodging/2000000/1070000/1060800/1060721/40afc3e4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Garden Place Hotel 6615 Transit Road Buffalo NY £60 9 Mar - 10 Mar includes taxes & fees Stay at this business-friendly hotel in Buffalo. Enjoy free parking, breakfast (surcharge) and a free airport shuttle. Our guests praise the helpful staff and ... 7.6/10 Good! (2,257 reviews) Friendly staff, clean rooms. Reviewed on 10 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F03%2F2026&endDate=10%2F03%2F2026&selected=1060721&PinnedHotelID=1060721&HadPinnedHotel=true®ionId=6338362) [See all 881 properties in Depew](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=15%2F02%2F2026&endDate=16%2F02%2F2026®ionId=6338362) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Cozy 3-bedroom house in charming Buffalo with WiFi, AC](https://images.trvl-media.com/lodging/108000000/107610000/107601000/107600912/19f14cda_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cozy 3-bedroom house in charming Buffalo with WiFi, AC Buffalo NY Stay at this apartment in Buffalo. Enjoy air conditioning. Popular attractions Walden Galleria Mall and KeyBank Center are located nearby. 8.4/10 Very Good! (15 reviews) Small but definitely perfect for a quick trip! Communication with owner was great and accommodating! Would book again! Reviewed on 25 Nov 2025 [](https://expedia.co.uk/Buffalo-Hotels-Cozy-3-Bedroom-House-In-Charming-Buffalo-With-WiFi.h107600912.Hotel-Information) ![Beautiful furnished 2 bdr great location Elmwood](https://images.trvl-media.com/lodging/77000000/76640000/76638000/76637970/w904h683x61y0-495f7e8f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Beautiful furnished 2 bdr great location Elmwood Buffalo NY Stay at this holiday home in Buffalo. Enjoy a garden, laundry facilities and cable/satellite TV service. Popular attractions KeyBank Center and Richardson Olmsted ... 9.4/10 Exceptional! (57 reviews) Great host. Very responsive. Place was clean and cozy Reviewed on 4 Feb 2026 [](https://expedia.co.uk/Buffalo-Hotels-Beautiful-Furnished-2-Bdr-Great-Location-Elmwood.h76637970.Hotel-Information) ![4 bedrooms & 3 bathrooms | Entire Home For Families 🏠](https://images.trvl-media.com/lodging/69000000/68460000/68459300/68459231/5e2e3cb2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 4 bedrooms & 3 bathrooms | Entire Home For Families 🏠 Buffalo NY Stay at this holiday home in Buffalo. Enjoy free Wi-Fi, an in-room coffee maker and air conditioning. Popular attractions Walden Galleria Mall and Glen Falls ... 9.6/10 Exceptional! (53 reviews) It was very clean, and easy to enter the property. Adequate space for the 7 of us to stay and towels were provided for showering as well as anything we could have needed to cook if we chose to. Host was very easy to communicate with. Reviewed on 29 Dec 2025 [](https://expedia.co.uk/Buffalo-Hotels-4-Bedrooms-3-Bathrooms-Entire-Home-For-Families.h68459231.Hotel-Information) [See all properties in Depew](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6338362&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Depew hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6338362&startDate=2026-02-14&endDate=2026-02-15)[14 Feb - 15 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6338362&startDate=2026-02-14&endDate=2026-02-15) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6338362&startDate=2026-02-15&endDate=2026-02-16)[15 Feb - 16 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6338362&startDate=2026-02-15&endDate=2026-02-16) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6338362&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026)[20 Feb - 22 Feb](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6338362&startDate=20%2F02%2F2026&endDate=22%2F02%2F2026) ### Popular places to visit ![A beautiful sunset today at ub! At least there is one perk to being stuck on campus for 12 hours! 🌅🌅🌅 #ub #universityatbuffalo #buffalo #sunset #baridpoint #oozefestpits #springsemester #academicspine #campuslife ](https://images.trvl-media.com/place/6276889/6f4929dc-5220-42a3-b540-54ed4dcc34d4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### University At Buffalo - North Campus Take a campus tour or just explore the area of University At Buffalo - North Campus during your trip to Amherst. Experience the area's great live music and acclaimed theatre scene. [](https://expedia.co.uk/University-At-Buffalo-North-Campus-Buffalo.d6175369.Attraction) ![NFL Salute to Service Buffalo Bills Ralph Wilson Stadium](https://images.trvl-media.com/place/6047844/967ffd8d-0ce5-4803-b2a8-0405cc2eb554.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Highmark Stadium Catch an event at Highmark Stadium during your trip to Orchard Park. Experience the area's great live music and entertainment choices. [](https://expedia.co.uk/Highmark-Stadium-Buffalo.d6058007.Attraction) ![Downtown Buffalo NY](https://images.trvl-media.com/place/6064435/ddc94cc9-ad1a-4fc7-b3a1-f2ba87b4fb62.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### KeyBank Center Catch an event at KeyBank Center during your trip to Buffalo. Experience the area's entertainment choices and acclaimed theatre scene. [](https://expedia.co.uk/KeyBank-Center-Buffalo.d6064435.Attraction) ![More food than I can eat.](https://images.trvl-media.com/place/7197/922e9321-3e29-44f2-bf8c-86af1e799246.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Walden Galleria Mall You can browse for the perfect souvenirs at Walden Galleria Mall during your visit to Cheektowaga. Experience the area's entertainment choices and great live music. [](https://expedia.co.uk/Walden-Galleria-Mall-Buffalo.d6129205.Attraction) ![Buffalo Zoo](https://images.trvl-media.com/place/6064383/9113c450-b475-40c1-9f7d-3a98c9f83927.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Buffalo Zoo See more than 1,200 animals at this small zoo in Buffalo’s Delaware Park. Explore the rainforest building or see the big cats of the African plains. [](https://expedia.co.uk/Buffalo-Zoo-North-Buffalo.d6064383.Attraction) ![Buffalo, USA-20 July, 2019: Burchfield Penney art center, an arts and educational institution part of Buffalo State College](https://images.trvl-media.com/place/6175436/e70a5c43-7604-442a-bc1e-c6a71f3818ad.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Buffalo State College Enjoy the student vibe when you visit Buffalo State College during your trip to Buffalo. Experience the area's entertainment choices and great live music. [](https://expedia.co.uk/Buffalo-State-College-Buffalo.d6175436.Attraction) ### Things to do ![TR is waiting to greet you!](https://mediaim.expedia.com/localexpert/672820/ce030e1b-f8b5-41d2-a399-b3942bfe2fd7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Theodore Roosevelt Inaugural National Historic Site Admission and Guided Tour £9 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/theodore-roosevelt-inaugural-national-historic-site-admission-and-guided-tour.a672820.activity-details) ![Niagara Falls Self-Guided Driving Audio Tour from Toronto](https://mediaim.expedia.com/localexpert/49289256/11eb9a03-8a54-418e-b42b-71b7c5463267.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Niagara Falls Self-Guided Driving Audio Tour from Toronto £12 per traveller [](https://expedia.co.uk/things-to-do/niagara-falls-self-guided-driving-audio-tour-from-toronto.a49289256.activity-details) ![Sunset Tour of Niagara Falls State Park with Firework Spectacular](https://mediaim.expedia.com/localexpert/48908284/0112a913-1d13-4a3a-ac13-4d4f4e73e3b3.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Sunset Tour of Niagara Falls State Park with Falls Illumination £21 per adult [](https://expedia.co.uk/things-to-do/sunset-tour-of-niagara-falls-state-park-with-falls-illumination.a48908284.activity-details) ![Niagara Falls USA: Full-Day Scenic Tour from Buffalo!](https://mediaim.expedia.com/localexpert/51257462/837189b6-b6bd-4923-918a-580219b6392b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Niagara Falls USA: Full-Day Scenic Tour from Buffalo! £110 per adult [](https://expedia.co.uk/things-to-do/niagara-falls-usa-full-day-scenic-tour-from-buffalo.a51257462.activity-details) ![Niagara Falls USA Tour with Maid of the Mist Boat Ride](https://mediaim.expedia.com/localexpert/49088693/37ef8e60-9d3a-48b4-be73-e15c11eaa636.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Niagara Falls USA Tour with Maid of the Mist Boat Ride £94 per adult [](https://expedia.co.uk/things-to-do/niagara-falls-usa-tour-with-maid-of-the-mist-boat-ride.a49088693.activity-details) ![Niagara Falls 1 Day Tour from NYC with Optional Maid of Mist Boat](https://mediaim.expedia.com/localexpert/50475022/c59d6176-d3d0-4f47-a376-c65a4f5f9a24.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Niagara Falls 1 Day Tour with Optional Maid of Mist Boat Ride from NYC £148 per adult [](https://expedia.co.uk/things-to-do/niagara-falls-1-day-tour-with-optional-maid-of-mist-boat-ride-from-nyc.a50475022.activity-details) [See all activities in Depew](https://expedia.co.uk/Things-To-Do-In-Depew.d6338362.Travel-Guide-Activities) ## Cities near Depew ![Buffalo showing central business district and a city](https://images.trvl-media.com/place/602674/2e814fbb-a528-4756-b39e-0a601a261b1d.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Buffalo ![#riverside #rivers #riverwalk #riverview #nature](https://images.trvl-media.com/place/7197/71fe938d-8fc9-4a1d-8f4f-c04943ec4751.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Cheektowaga ![Outdoor view of Amish horse and carriage travels on a road in Lancaster County](https://images.trvl-media.com/place/6135833/7e53dd77-9f5c-4cb7-ab5e-3d36de156ae6.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Lancaster - Cities near Depew - Places of interest [Buffalo](https://expedia.co.uk/Buffalo.dx602674)[Cheektowaga](https://expedia.co.uk/Cheektowaga.dx7197)[Lancaster](https://expedia.co.uk/Lancaster.dx6135833) - [University At Buffalo - North Campus ](https://expedia.co.uk/University-At-Buffalo-North-Campus-Buffalo.d6175369.Attraction) - [Highmark Stadium ](https://expedia.co.uk/Highmark-Stadium-Buffalo.d6058007.Attraction) - [Walden Galleria Mall ](https://expedia.co.uk/Walden-Galleria-Mall-Buffalo.d6129205.Attraction) - [Buffalo City Hall ](https://expedia.co.uk/Buffalo-City-Hall-Downtown-Buffalo.d6064381.Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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