Title: Hotels in Defiance, MO - Best Defiance Hotels from £53 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Defiance](https://expedia.co.uk/Defiance-Holiday-Rentals.d6353634.Travel-Guide-HolidayRentals)[Defiance Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Defiance.d6353634.Car-Hire-Guide)[Defiance Holidays](https://expedia.co.uk/Defiance.d6353634.Holidays-City-Breaks) ![A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Defiance Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&amenities=POOL) Apart hotel [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&lodging=APART_HOTEL) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&amenities=PETS) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&lodging=CABIN) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&lodging=APARTMENT) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&amenities=HOT_TUB) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&lodging=COTTAGE) Condo [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&lodging=CONDO) Waterpark [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&amenities=WATER_PARK) Chalet [](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-04-21&d1=2026-04-21&endDate=2026-04-23&d2=2026-04-23&lodging=CHALET) ## Check prices for these dates Tonight [7 Apr - 8 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6353634&startDate=2026-04-07&endDate=2026-04-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [8 Apr - 9 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6353634&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6353634&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Apr - 19 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6353634&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Defiance hotels ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/b53f4594.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/aadfb5be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/c9087452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking | Living area | LCD TV](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/49aae62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) Fenton 8.0/10 Very good (1,184 reviews) "Everything was great for overnight stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Regina £78 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/188fac9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/51c38da4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/ac863486.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/130000/124500/124484/97b3b5d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Warrenton [](https://www.expedia.co.uk/Warrenton-Hotels-Baymont-By-Wyndham-Warrenton.h124484.Hotel-Information) Warrenton 7.6/10 Good (1,000 reviews) "The room was clean. The parking was easy." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris £64 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Warrenton-Hotels-Baymont-By-Wyndham-Warrenton.h124484.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/40200/40102/5429427c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40200/40102/81efc7c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40200/40102/5ea02394.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/50000/40200/40102/be84c5ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham St. Louis/Fenton Route 66 [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Fenton.h40102.Hotel-Information) Fenton 7.8/10 Good (1,187 reviews) "Great location, comfy and clean rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nestor £73 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Pear-Tree-Inn-St-Louis-Fenton.h40102.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108930000/108922000/108921961/20625a7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108930000/108922000/108921961/fadbec1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108930000/108922000/108921961/8d754889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108930000/108922000/108921961/aa17bcae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WoodSpring Suites St Peters-OFallon [](https://www.expedia.co.uk/St-Louis-Hotels-Woodspring-Suites-St-Peters-Ofallon.h108921961.Hotel-Information) St. Peters 8.8/10 Excellent (73 reviews) "Nice hotel with good staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £80 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Woodspring-Suites-St-Peters-Ofallon.h108921961.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16210/55269a5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16210/34f8e499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, pillow-top beds, desk](https://images.trvl-media.com/lodging/1000000/20000/16300/16210/140ce6ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16300/16210/2adbd684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Foristell [](https://www.expedia.co.uk/Warrenton-Hotels-Quality-Inn.h16210.Hotel-Information) Foristell 8.2/10 Very good (961 reviews) "Comfy beds, but the trim, doors, and other finishings look pretty rough and in need of replacement. Simple enough breakfast and was just there for a night to sleep so it did the job." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura £75 includes taxes & fees 21 Apr - 22 Apr [](https://www.expedia.co.uk/Warrenton-Hotels-Quality-Inn.h16210.Hotel-Information) ![Property entrance](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Jetted bathtub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/801c113b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/9fbd251c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Jetted Tub | Jetted bathtub](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/66ab3de8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Wildwood Hotel [](https://www.expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) Wildwood 9.2/10 Wonderful (1,635 reviews) "Staff was wonderful, location is great for our needs, and it was a quiet stay-which we loved. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica £78 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/42200/42127/04c6573d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/42200/42127/0d3776cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42127/b1c04063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42127/aa8717f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Fenton [](https://www.expedia.co.uk/St-Louis-Hotels-Best-Western-Plus-Fenton.h42127.Hotel-Information) Fenton 9.2/10 Wonderful (252 reviews) "Easy parking, friendly staff, clean and comfy rooms. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jan £86 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Best-Western-Plus-Fenton.h42127.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/d446d190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/9950450a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/b52a585e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17400000/17395600/17395579/41a6853d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn St. Louis Wentzville [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-By-Hilton-Wentzville.h17395579.Hotel-Information) Wentzville 9.0/10 Wonderful (685 reviews) "Very pet friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara £103 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-By-Hilton-Wentzville.h17395579.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/68bc6d17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/cf4e5d0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/0c7d61f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/41500/41453/c689fe3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St. Louis St. Peters [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-St-Peters.h41453.Hotel-Information) St. Peters 9.4/10 Exceptional (1,009 reviews) "Great stay! Very clean and staff was very nice. Definitely will be staying there on my return visit to the area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roxanne £96 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-St-Peters.h41453.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/1d22ac52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Queen Accessible Roll In Shower, Non Smoking | Blackout curtains, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/7c7fdb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/15695a25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/30000/20200/20181/68b7c425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn St. Charles St. Peters [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information) St. Charles 8.0/10 Very good (1,006 reviews) "Everything was great as always at this location as i have stayed here many times" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory £99 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Hampton-Inn-St-LouisSt-Charles.h20181.Hotel-Information) ![Standard Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/470000/460100/460034/4f8a0b30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/470000/460100/460034/0603ac51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/1000000/470000/460100/460034/6bd71e4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/470000/460100/460034/b2add733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Warrenton [](https://www.expedia.co.uk/Warrenton-Hotels-Super-8-By-Wyndham-Warrenton.h460034.Hotel-Information) Warrenton 7.4/10 Good (639 reviews) "The parking was easy, the room was verry clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary £48 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Warrenton-Hotels-Super-8-By-Wyndham-Warrenton.h460034.Hotel-Information) ![Premium bedding, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/07f8c63c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/c98607b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/5cdbca92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/c413cfac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites O'Fallon MO - Technology Drive [](https://www.expedia.co.uk/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information) O'Fallon 9.0/10 Wonderful (1,000 reviews) "This was one of our best stays ever nice hot breakfast. Clean room nice staff will stay again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lavania £75 includes taxes & fees 15 Apr - 16 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/d38dcff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 9:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/ac681623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/50b5788d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/36000000/35850000/35848800/35848753/da587b35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Wentzville St Louis West by IHG [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-Suites-Wentzville-St-Louis-West.h35848753.Hotel-Information) Wentzville 9.4/10 Exceptional (890 reviews) "Great location, clean, modern, killer shower and good bed! I would definitely recommend!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £122 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-Suites-Wentzville-St-Louis-West.h35848753.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/6093d918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/159a98ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/b493e570.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking (2 Queen, 2 Person Sofa Bed) | In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/68f10652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites St Charles - St Louis [](https://www.expedia.co.uk/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information) St. Charles 8.4/10 Very good (1,004 reviews) "The breakfast was good. They had two different waffle choices every day. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Josephine £85 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/10100/10074/b34d85ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/10100/10074/d5af958a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/20000/10100/10074/58b9b7e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/10100/10074/109bb8e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Near Six Flags St. Louis [](https://www.expedia.co.uk/Pacific-Hotels-Quality-Inn-Near-Six-Flags-St-Louis.h10074.Hotel-Information) Pacific 8.4/10 Very good (369 reviews) "Breakfast menu is extremely limited. Breakfast does not have bread/ butter." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Arinjay £94 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/Pacific-Hotels-Quality-Inn-Near-Six-Flags-St-Louis.h10074.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/7000000/6580000/6575600/6575600/665da1a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6580000/6575600/6575600/9ef66b46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6580000/6575600/6575600/9b53533a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6575600/6575600/70696573.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites Wentzville [](https://www.expedia.co.uk/Wentzville-Hotels-Fairfield-Inn-Suites-Wentzville.h6575600.Hotel-Information) Wentzville 9.0/10 Wonderful (667 reviews) "Property was nice, easy check-in, nice breakfast, room was clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Doris £111 includes taxes & fees 14 Apr - 15 Apr [](https://www.expedia.co.uk/Wentzville-Hotels-Fairfield-Inn-Suites-Wentzville.h6575600.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/7000000/6720000/6717700/6717650/ec725621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6720000/6717700/6717650/653f0674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/7000000/6720000/6717700/6717650/bbfa014c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6720000/6717700/6717650/78731ffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cedar Creek [](https://www.expedia.co.uk/Washington-Hotels-Cedar-Creek.h6717650.Hotel-Information) New Haven 9.0/10 Wonderful (265 reviews) "Loved the views and the old west buildings " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shelly £117 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Washington-Hotels-Cedar-Creek.h6717650.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/3a1e3bea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/d4f404b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (with Sofabed) | Egyptian cotton sheets, premium bedding, pillow-top beds, desk](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/fecb1b2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free full breakfast ](https://images.trvl-media.com/lodging/2000000/1080000/1077200/1077183/70eb43b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Washington Hotel [](https://www.expedia.co.uk/Washington-Hotels-Best-Western-Plus-Washington-Hotel.h1077183.Hotel-Information) Washington 9.2/10 Wonderful (671 reviews) "Great stay and accommodations. The pool was very nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shane £111 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Washington-Hotels-Best-Western-Plus-Washington-Hotel.h1077183.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/416a6a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/56c93a46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/046d0e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/f8b9cd17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Southwest St. Louis [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-Southwest-St-Louis.h976140.Hotel-Information) Valley Park 9.6/10 Exceptional (1,008 reviews) "Very clean place with great food and friendly staff. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Kara £105 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-Southwest-St-Louis.h976140.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/cb1b5cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/0c098574.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/76ca3207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hollywood Casino & Hotel St. Louis [](https://www.expedia.co.uk/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) Maryland Heights 8.4/10 Very good (2,195 reviews) "Great hotel for the hockey tournament... very nice staff... great location. The air quality was poor nearing the casino and awful inside... otherwise a great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alex £108 includes taxes & fees 8 Apr - 9 Apr [](https://www.expedia.co.uk/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-21&endDate=2026-04-22®ionId=6353634&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDefiance-Hotels.d6353634.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDefiance-Hotels.d6353634.Travel-Guide-Hotels) ## Stay near popular Defiance attractions ![](https://images.trvl-media.com/place/553248621532648567/f82f9409-75a2-47f3-a8fc-2d7c278cc07c.jpg) Photo by Pages of Travel ### Chandler Hill Vineyards This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532648567) ![Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri](https://images.trvl-media.com/place/6160337/5138d652-49fb-41de-8fd4-a7bb27471f3e.jpg) ### August A. Busch Memorial Conservation Area This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6160337) ### Historic Daniel Boone Home and Heritage Center 4.8/5 (4 reviews) Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532648566) ### Matson Hill Park Trailhead Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendour. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=641530089696399360) ### Sugar Creek Winery Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532648612) ### Yellow Farmhouse Winery This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532648568) ### Broemmelsiek Park This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621561876810) ### Hamburg Trail Trailhead This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=641529175733194752) ## Learn more about Defiance Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside. [See all hotels in Defiance](https://www.expedia.co.uk/Hotel-Search?startDate=2026-04-21&endDate=2026-04-22&adults=2®ionId=6353634) ![A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Defiance Hotel Reviews ![Hollywood Casino & Hotel St. Louis](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/76ca3207_y.jpg) ### Hollywood Casino & Hotel St. Louis 8/10 Good "Easy to find" [](https://expedia.co.uk/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information) ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/70b128db_y.jpg) ### Ameristar Casino Resort and Spa 8/10 Good "The room was great and clean. This was supposed to have a pool and spa but it wasn’t open or available " [](https://expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c_y.jpg) ### The Wildwood Hotel 10/10 Excellent "Nice hotel in a nice area! We had 3 adults in 3 separate rooms with 2 dogs along, and everything was great. We walked across the street one day to catch a movie at the theater. Another day, I walked to the Starbucks close by. One suggestion - they need to update the pictures of the hotel on the internet. It looks quite different from the pics." [](https://expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Drury Plaza Hotel St. Louis Creve Coeur](https://images.trvl-media.com/lodging/1000000/80000/74700/74657/b9326e72_y.jpg) ### Drury Plaza Hotel St. Louis Creve Coeur 10/10 Excellent "Wonderful! " [](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Creve-Coeur.h74657.Hotel-Information) ![Embassy Suites by Hilton St. Louis St. Charles](https://images.trvl-media.com/lodging/2000000/1140000/1131200/1131105/ac68aac2_y.jpg) ### Embassy Suites by Hilton St. Louis St. Charles 10/10 Excellent "Will stay here again when in the St. Louis area, nice staff and hotel. Enjoyed my stay." [](https://expedia.co.uk/St-Louis-Hotels-Embassy-Suites-St-Louis-St-Charles.h1131105.Hotel-Information) ![Drury Plaza Hotel St. Louis St. Charles](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/79d56802_y.jpg) ### Drury Plaza Hotel St. Louis St. Charles 8/10 Good "The bed was comfortable and the room was clean. The breakfast however was not great, I guess pretty standard hotel food, but not very tasty." [](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information) ![Drury Plaza Hotel St. Louis Chesterfield](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/69d580ec_y.jpg) ### Drury Plaza Hotel St. Louis Chesterfield 10/10 Excellent "Staff was very friendly and helpful. Property was well maintained and clean with plenty of amenities above regular hotel standard at an affordable price. " [](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) ![Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham](https://images.trvl-media.com/lodging/1000000/50000/42200/42122/b53f4594_y.jpg) ### Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham 10/10 Excellent "The room and hotel was clean. The staff was very helpful and friendly. Only complaint was that the pool was very cold! To be inside I wish it was a little warmer " [](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Fenton.h42122.Hotel-Information) ![La Quinta Inn & Suites by Wyndham St. Louis Westport](https://images.trvl-media.com/lodging/1000000/70000/62900/62842/2d27fd02_y.jpg) ### La Quinta Inn & Suites by Wyndham St. Louis Westport 6/10 Okay "Breakfast were really good, the room was clean and roomie. However, there was a lot of noise at night on the third floor. Kids were running around naked up there celebrating the 18 year-old party there was no supervision and running up and down the halls in the wee hours of the morning, smoking dope the whole hallways melt of marijuana and it was very offensive to me and my husband. " [](https://expedia.co.uk/St-Louis-Hotels-La-Quinta-Inn-Suites-By-Wyndham-St-Louis-Westport.h62842.Hotel-Information) ## More cheap stays in Defiance ![Relax Inn Saint Charles ](https://images.trvl-media.com/lodging/2000000/1010000/1000800/1000712/49b4298c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Relax Inn Saint Charles 3800 Harry S Truman Blvd St. Charles MO £53 25 Apr - 26 Apr includes taxes & fees 6.8/10 (1,001 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Relax-Inn-Saint-Charles.h1000712.Hotel-Information) ![Days Inn and Suites by Wyndham St. Louis/Westport Plaza](https://images.trvl-media.com/lodging/1000000/60000/55200/55161/40483d14_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn and Suites by Wyndham St. Louis/Westport Plaza 1970 Craig Rd Maryland Heights MO £60 12 Apr - 13 Apr includes taxes & fees 4.6/10 (1,002 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Days-Inn-And-Suites-By-Wyndham-St-LouisWestport-Plaza.h55161.Hotel-Information) ![Sleep Inn & Suites O'Fallon MO - Technology Drive](https://images.trvl-media.com/lodging/16000000/15590000/15583900/15583887/07f8c63c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sleep Inn & Suites O'Fallon MO - Technology Drive 1147 Technology Drive O'Fallon MO £75 15 Apr - 16 Apr includes taxes & fees 9/10 Wonderful! (1,006 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Sleep-Inn-Suites-OFallon-MO-Technology-Drive.h15583887.Hotel-Information) ![Comfort Suites St Charles - St Louis](https://images.trvl-media.com/lodging/1000000/670000/664500/664414/6093d918_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Comfort Suites St Charles - St Louis 1400 S 5th St St. Charles MO £77 3 May - 4 May includes taxes & fees 8.4/10 Very Good! (1,004 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Comfort-Suites-St-Charles-St-Louis.h664414.Hotel-Information) ![Best Western Plus St. Louis West-Westport](https://images.trvl-media.com/lodging/1000000/50000/41500/41448/00255b25_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Best Western Plus St. Louis West-Westport 12220 Dorsett Rd Maryland Heights MO £81 9 Apr - 10 Apr includes taxes & fees 8/10 Very Good! (1,060 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Best-Western-Plus-St-Louis-West-Westport.h41448.Hotel-Information) ![Country Inn & Suites by Radisson, St. Charles Historic District](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/001d26f2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Country Inn & Suites by Radisson, St. Charles Historic District 1190 S Main St St. Charles MO £117 3 May - 4 May includes taxes & fees 9.4/10 Exceptional! (1,006 reviews) [](https://expedia.co.uk/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information) ## Find out more about Defiance ### Top reasons to visit Defiance - **Scenic Outdoor Activities:** Defiance boasts beautiful hiking trails and recreational areas, perfect for nature lovers and adventurers alike. - **Charming Downtown:** Enjoy a leisurely stroll through downtown Defiance, where friendly locals and unique shops create a delightful atmosphere. - **Rich Historical Sites:** Explore historical attractions like Fort Defiance, offering insights into the region's past. - **Romantic Getaways:** Ideal for couples, Defiance provides a picturesque setting for a romantic escape. - **Diverse Accommodation Options:** From cosy motels to welcoming hotels, Defiance caters to all types of travellers. ### Find great hotels near Defiance Discover a range of charming accommodations in Defiance, Missouri, perfect for every type of visitor. From pet-friendly motels to business-oriented hotels, Defiance offers a welcoming atmosphere for all, including LGBTQIA travellers. Whether you're seeking a cosy suite or looking to compare hotels for the best fit, you're sure to find the ideal lodging for your vacation needs. - **[Sonesta ES Suites St. Louis - Chesterfield: ](https://www.expedia.co.uk/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information)** Emphasising a pet-friendly atmosphere, Sonesta ES Suites St. Louis - Chesterfield is a welcoming retreat for travellers seeking comfort alongside their furry companions. Located 7.5km from Defiance, this 3-star hotel offers an array of amenities designed for a relaxing stay, including spacious suites equipped with kitchenettes, ideal for extended vacations. The property’s pet-friendly policy ensures that your pets are accommodated, with thoughtful features such as food and water bowls provided. This hotel is perfect for those looking for a laid-back experience with their pets in tow. - **[The Wildwood Hotel: ](https://www.expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information)** A charming blend of business and leisure, The Wildwood Hotel is situated 5.6km from Defiance and boasts a 3.5-star rating. This hotel caters to both business travellers and those seeking an adventurous ski getaway. With convenient access to ski lifts and shuttles, along with comprehensive business amenities such as a 24-hour business centre and multiple meeting rooms, it ensures a productive stay. The pet-friendly policy complements the inviting atmosphere, making it an excellent choice for guests who wish to bring their pets along for the adventure. - **[Hyatt Place St. Louis/Chesterfield: ](https://www.expedia.co.uk/St-Louis-Hotels-Hyatt-Place-St-LouisChesterfield.h6583788.Hotel-Information)** This 3-star hotel, located 7.5km from Defiance, is designed for families, business travellers, and pet owners alike. Hyatt Place St. Louis/Chesterfield features spacious rooms and a variety of amenities, including a business centre and meeting rooms for corporate needs. Families will appreciate the child-friendly services offered. The hotel's pet policy allows for dogs, ensuring that your four-legged friends can join in your travels, making it a versatile option for all types of visitors. ### Where to stay in and around Defiance Defiance, Missouri, offers a delightful blend of outdoor adventures and romantic getaways, perfect for tourists seeking a charming escape. Explore the rich historical vibes of the city and its surrounding areas, including the family-friendly atmosphere of nearby towns. Don’t miss a stroll through downtown Defiance, where friendly locals and unique shops enhance your experience. Whether you’re after leisure or adventure, Defiance promises a memorable holiday for every traveller. - **[Chesterfield: ](https://www.expedia.co.uk/Chesterfield-Hotels.d9530.Travel-Guide-Hotels)** A vibrant city located 7.5km from Defiance, Chesterfield offers a delightful blend of family-friendly entertainment and urban charm. With visitor numbers peaking in April and during the summer months, this city is perfect for a lively getaway. Attractions like the arcade adventure zone, theatre, and amusement park ensure that there’s never a dull moment. Don’t miss the local theme park and stadium, which serve as key landmarks, making Chesterfield an ideal spot for those seeking a fun-filled experience. - **[Saint Albans: ](https://www.expedia.co.uk/Saint-Albans-Hotels.d3000445473.Travel-Guide-Hotels)** Just 2.5km from Defiance, Saint Albans is a picturesque city that caters to outdoor enthusiasts and families alike. Known for its adventure experiences, the city sees a peak in visitor numbers from April, July, and September. You can explore various attractions, including an arcade adventure zone, amusement park, and shopping centre. With the stunning lake and convention centre nearby, Saint Albans promises an exciting blend of leisure and exploration, making it perfect for a day trip or a weekend retreat. - **[Hamburg: ](https://www.expedia.co.uk/Hamburg-Hotels.d553248635975869538.Travel-Guide-Hotels)** Nestled within the vicinity of Defiance, the charming village of Hamburg is an inviting destination for families and outdoor adventure seekers. Although smaller in scale, Hamburg attracts visitors mainly during the summer months of June to August. Here, you can enjoy activities at the local arcade adventure zone, while the urban park and scenic water features provide a tranquil backdrop for relaxation and exploration. Hamburg’s welcoming atmosphere makes it an excellent stop for those wanting to experience a quieter side of the region. ### Things to do in and around Defiance Defiance, Missouri, is an ideal destination for outdoor enthusiasts and couples seeking a romantic getaway. Visitors can enjoy a variety of activities, including access to recreational areas and scenic hiking trails, perfect for exploring the natural beauty of the region. Whether you're looking to relax or embark on an adventure, Defiance offers a delightful mix of entertainment and tranquillity for a memorable vacation. **Shopping** For a delightful shopping experience in Defiance, visit St. Louis Premium Outlets, only 4.3km away, offering a variety of family-friendly shops. If you're up for a drive, the [Westfield Chesterfield Mall](https://www.expedia.co.uk/Westfield-Chesterfield-Mall-Hotels.0-l6190516-0.Travel-Guide-Filter-Hotels) and Wentzville Flea Market are both within 8.1km, providing diverse shopping options and vibrant atmospheres. **Recreation** Explore Broemmelsiek Park for a serene retreat, where you can enjoy leisurely walks and connect with nature. For sport enthusiasts, Missouri Bluffs Golf Course offers a fantastic outdoor golfing experience, while The Factory provides lively entertainment with music concerts, perfect for unwinding after a day of activities. **Adventure** Hidden Valley Ski Resort offers thrilling skiing experiences, located 5.6km from Defiance, perfect for snow sports enthusiasts. For nature lovers, Matson Hill Park Trailhead provides stunning outdoor trails right in Defiance, while Hurricane Harbor, situated 6.2km away, promises a fun-filled day at the water park for families. **Nightlife** For a lively evening in Defiance, consider visiting Chesterfield Sports Fusion, an exciting arcadeAdventureZone only 5.6km away, perfect for families. Alternatively, the St. Louis Carousel, 8.1km away, offers delightful amusement rides, while the New Jewish Theatre, 12.4km distant, presents a charming cultural experience. ### Booking tips and Expedia advantages for Defiance For a budget-friendly visit to Defiance, consider travelling between December and February when accommodation prices are lower. Mondays are the most economical days to book your stay, while Saturdays tend to be pricier. Use Expedia’s search tool to filter by budget and eco-friendly options, and sort by price to uncover the best deals. Combining your hotel, flights, and activities into a package can also lead to significant savings. Look for local free activities to enhance your experience without straining your wallet. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Defiance are December to February, where the prices are slightly lower. This is in comparison to May to July, where prices are slightly higher. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Defiance is Monday. The most expensive day to stay in Defiance is Saturday. - **Find cheap hotels on Expedia:** Utilise Expedia’s search tool to refine your preferences, such as your budget, preferred location, and type of accommodation. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels currently available. To find the most affordable prices and special offers, simply sort the price filter from lowest to highest. - **Consider bundling your trip:** You might find it more economical to combine your hotel reservation in Defiance with your flights and activities by opting for an Expedia package. ### Find the best attractions near Defiance Defiance, Missouri, is an excellent destination for an outdoor, romantic getaway, offering a blend of entertainment and scenic beauty. Visitors can explore local attractions such as Fort Defiance and enjoy the nearby state and urban parks. With activities ranging from family-friendly adventures to urban experiences, Defiance caters to all types of travellers seeking a memorable holiday in a picturesque setting. - **[Route 66 State Park: ](https://www.expedia.co.uk/Route-66-State-Park-Hotels.0-l6292976-0.Travel-Guide-Filter-Hotels)** Explore the nostalgia of America’s Mother Road at Route 66 State Park, where you can enjoy scenic trails, picnicking, and the chance to connect with nature. The park showcases beautiful landscapes and offers a glimpse into the historic significance of this iconic route. - **Six Flags St. Louis:** Perfect for families, Six Flags St. Louis boasts thrilling rides, entertaining shows, and a variety of attractions. Enjoy a day filled with adventure as you experience roller coasters and family-friendly rides in a vibrant outdoor setting. - **Purina Farms:** At Purina Farms, immerse yourself in the charm of rural life. This scenic farm offers interactive experiences with animals, including dog shows and educational exhibits, making it a delightful stop for visitors of all ages. ### Best time to go to Defiance The best time to visit Defiance is dependant on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are moderately high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly cloudy with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 31.6°F (-0.2°C) | Light Rain | Mostly Cloudy | Moderately Low | Slightly Low | | February | 34.7°F (1.5°C) | Light Rain | Mostly Sunny | Average | Average | | March | 46.4°F (8.0°C) | Light Rain | Mostly Sunny | Average | Average | | April | 55.9°F (13.3°C) | Light Rain | Mostly Sunny | Moderately High | Average | | May | 66.2°F (19.0°C) | Light Rain | Mostly Sunny | Average | Slightly High | | June | 75.9°F (24.4°C) | Light Rain | Mostly Sunny | Average | Slightly High | | July | 79.0°F (26.1°C) | Light Rain | Mostly Sunny | Moderately High | Slightly High | | August | 77.2°F (25.1°C) | Light Rain | Mostly Sunny | Average | Average | | September | 70.9°F (21.6°C) | Light Rain | Mostly Sunny | Moderately High | Average | | October | 58.5°F (14.7°C) | Light Rain | Mostly Sunny | Average | Average | | November | 46.2°F (7.9°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly Low | | December | 37.6°F (3.1°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly Low | ### The nearest major airports for your trip to Defiance Defiance, Missouri, can be easily accessed via two major airports. St. Louis Lambert International Airport ([STL](https://www.expedia.co.uk/Lambert-St-Louis-Intl-Airport-Hotels.0-aSTL-0.Travel-Guide-Filter-Hotels)) is situated 14.3km away and offers nearby luxury accommodations such as [The Ritz-Carlton](https://www.expedia.co.uk/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information) and [Ameristar Casino Resort and Spa](https://www.expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information), both approximately 4.3km from the airport. Another option is Spirit of St. Louis Airport (SUS), located 4.3km from Defiance, with convenient hotel options like the [DoubleTree by Hilton Hotel St. Louis - Chesterfield](https://www.expedia.co.uk/St-Louis-Hotels-DoubleTree-By-Hilton-Hotel-St-Louis-Chesterfield.h3258.Hotel-Information), just 2.5km away, and [The Wildwood Hotel](https://www.expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information), 3.7km from the airport. Both airports provide accessible transport links to these hotels, ensuring a comfortable stay for visitors. ## Frequently asked questions ### What is the best area to stay in Defiance? > This area is the heart of Defiance, offering a collection of local businesses, dining options, and access to the Katy Trail. It's a small, walkable village with a relaxed pace, surrounded by scenic vineyards and rolling hills. The historic Defiance Roadhouse is a popular landmark here. > > > For couples looking for a romantic getaway, the village centre is ideal. You'll find boutique accommodation options, often with a focus on local wines and cuisine. It's great for enjoying leisurely meals, exploring the nearby wineries, and taking peaceful walks along the Katy Trail. > > > Solo travellers seeking a peaceful retreat and outdoor activities will also find the village centre appealing. ### When is the best time to go to Defiance? > Spring offers mild temperatures, making it ideal for outdoor activities like cycling and hiking along the Katy Trail. The vineyards begin to bud, and the countryside is lush and green. This period is particularly good for couples who enjoy scenic walks and wine tasting without the summer crowds. > > > Autumn brings cooler, crisp air and the stunning transformation of the leaves, creating a picturesque backdrop for exploring the region. Many local wineries also host harvest festivals during this time. For those who appreciate outdoor beauty and a relaxed pace, this season provides an excellent experience. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Defiance hotel booking with Expedia? ### How much is the nightly rate at a Defiance hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [5 Star Hotels in Chesterfield ](https://www.expedia.co.uk/5Star-Chesterfield-Hotels.s50-0-d9530.Travel-Guide-Filter-Hotels) - [Augusta Hotels ](https://www.expedia.co.uk/Augusta-Hotels.d6250878.Travel-Guide-Hotels) - [Ballwin Hotels ](https://www.expedia.co.uk/Ballwin-Hotels.d6354554.Travel-Guide-Hotels) - [Hotels near CarShield Field ](https://www.expedia.co.uk/CarShield-Field-Hotels.0-l681801061030821888-0.Travel-Guide-Filter-Hotels) - [Serviced Apartments in Chesterfield ](https://www.expedia.co.uk/Chesterfield-Apart-Hotels.d9530-aaApartHotels.Travel-Guide-Accommodation) - [Cheap Hotels in Chesterfield ](https://www.expedia.co.uk/Chesterfield-Hotels-Budget-Hotels.0-0-d9530-tBudgetHotels.Travel-Guide-Filter-Hotels) - 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