Title: Holiday Rentals Defiance from £169: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk

[Hotels in Defiance](https://expedia.co.uk/Defiance-Hotels.d6353634.Travel-Guide-Hotels)[Defiance Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Defiance.d6353634.Car-Hire-Guide)[Defiance Holidays](https://expedia.co.uk/Defiance.d6353634.Holidays-City-Breaks)

![A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6353634&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6353634&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[8 May - 10 May](https://www.expedia.co.uk/Hotel-Search?regionId=6353634&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[5 Jun - 7 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=6353634&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Defiance holiday rentals

![Smart TV, books](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/016cf9b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/5742a366.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/45965e2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/83000000/82760000/82756500/82756479/f2f70f1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa de Saint Charles

[](https://www.expedia.co.uk/St-Louis-Hotels-Casa-De-Saint-Charles.h82756479.Hotel-Information)

Saint Charles

9.2/10

Wonderful

(17 reviews)

"We group of senior ladies thoroughly enjoyed our weekend at Casa de Saint Charles. The accommodations were perfect, inside and out. Our hosts were very accessible and made sure all our wants and needs were taken care of. What a wonderful home! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Rosalind W.

£242

includes taxes & fees

16 Feb - 17 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Casa-De-Saint-Charles.h82756479.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/104000000/103900000/103890100/103890008/8d0398a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/104000000/103900000/103890100/103890008/4c428d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/104000000/103900000/103890100/103890008/08562f32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/104000000/103900000/103890100/103890008/84e2410f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

[](https://www.expedia.co.uk/Augusta-Hotels-WELCOME-TO-THE-OWLS-NEST-2-BEDROOM-HOME-IN-AUGUSTA.h103890008.Hotel-Information)

Augusta

10/10

Exceptional

(30 reviews)

"Adorable place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amy F.

£205

includes taxes & fees

17 Feb - 18 Feb

[](https://www.expedia.co.uk/Augusta-Hotels-WELCOME-TO-THE-OWLS-NEST-2-BEDROOM-HOME-IN-AUGUSTA.h103890008.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/w905h683x60y0-7da69c98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/w507h683x260y0-03493f60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/f45a4107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/ca1dea43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TJ’s Country Getaway- Dog Friendly

[](https://www.expedia.co.uk/Union-Hotels-TJs-Country-Getaway.h71507563.Hotel-Information)

Union

10/10

Exceptional

(45 reviews)

"It had everything you need for a relaxing stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judith

£108

includes taxes & fees

17 Feb - 18 Feb

[](https://www.expedia.co.uk/Union-Hotels-TJs-Country-Getaway.h71507563.Hotel-Information)

![Smart TV, books](https://images.trvl-media.com/lodging/96000000/95370000/95367100/95367068/7c47509f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children’s area](https://images.trvl-media.com/lodging/96000000/95370000/95367100/95367068/6ffa92aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/96000000/95370000/95367100/95367068/2495d98c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/96000000/95370000/95367100/95367068/d9740cc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Robins Nest by Innsbrook Vacations!

[](https://www.expedia.co.uk/Wright-City-Hotels-The-Robins-Nest-By-Innsbrook-Vacations.h95367068.Hotel-Information)

Innsbrook

9.6/10

Exceptional

(5 reviews)

"Amazing place and property nearby, the overflow from lake is a must see . Just like a waterfall"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John S.

£385

includes taxes & fees

8 Mar - 9 Mar

[](https://www.expedia.co.uk/Wright-City-Hotels-The-Robins-Nest-By-Innsbrook-Vacations.h95367068.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/114000000/113700000/113690800/113690723/7f7794c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/114000000/113700000/113690800/113690723/29fe4dad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/114000000/113700000/113690800/113690723/8a1ec7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace](https://images.trvl-media.com/lodging/114000000/113700000/113690800/113690723/6b051d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tamm Loft | River view, Downtown WashMo, Dog-friendly

[](https://www.expedia.co.uk/Washington-Hotels-Tamm-Loft-River-View.h113690723.Hotel-Information)

Washington

10/10

Exceptional

(18 reviews)

"This is a beautiful place , well equipped kitchen . It was very clean too . It has located downtown and many restaurants in walking distance"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Johanna D.

£248

includes taxes & fees

11 Feb - 12 Feb

[](https://www.expedia.co.uk/Washington-Hotels-Tamm-Loft-River-View.h113690723.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/1e8558f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/f3578af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/a7d9ee80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/5ed26783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Rustic Augusta Cabin by StayLage

[](https://www.expedia.co.uk/Augusta-Hotels-Rustic-Augusta-Cabin-By-StayLage.h110062605.Hotel-Information)

Augusta

9.2/10

Wonderful

(5 reviews)

"I booked this place wit spend some homely time with my kids and it was amazing, the place was clean they even dropped off some extra towels without us having to ask, it was truly amazing. Will definitely stay there again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

teresa s.

£231

includes taxes & fees

17 Feb - 18 Feb

[](https://www.expedia.co.uk/Augusta-Hotels-Rustic-Augusta-Cabin-By-StayLage.h110062605.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/5d45ed4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/7d7d40ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/0589f65d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/46f64c9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Adorable Augusta Cabin

[](https://www.expedia.co.uk/Augusta-Hotels-Adorable-Augusta-Cabin.h110062608.Hotel-Information)

Augusta

9.0/10

Wonderful

(10 reviews)

"Absolutely beautiful area. Cabin is so cozy"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Aaron

£156

includes taxes & fees

15 Feb - 16 Feb

[](https://www.expedia.co.uk/Augusta-Hotels-Adorable-Augusta-Cabin.h110062608.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102400000/102390100/102390052/88a8c36e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/103000000/102400000/102390100/102390052/45cfe29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, fireplace, books, computer monitors](https://images.trvl-media.com/lodging/103000000/102400000/102390100/102390052/19c9294d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, iron/ironing board, travel cot](https://images.trvl-media.com/lodging/103000000/102400000/102390100/102390052/215e17d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Hidden Gem - 2BR Basement Apartment on 7 Acres

[](https://www.expedia.co.uk/Moscow-Mills-Hotels-The-Hidden-Gem-2BR-Basement-Apartment-On-7-Acres.h102390052.Hotel-Information)

Moscow Mills

10/10

Exceptional

(12 reviews)

"Great place, nice neighborhood. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Julie L.

£203

includes taxes & fees

11 Feb - 12 Feb

[](https://www.expedia.co.uk/Moscow-Mills-Hotels-The-Hidden-Gem-2BR-Basement-Apartment-On-7-Acres.h102390052.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/115000000/114780000/114776200/114776148/46289692.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114780000/114776200/114776148/25e66eb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114780000/114776200/114776148/aa66c9c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/115000000/114780000/114776200/114776148/aaec6313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious Cottage on Main st- Near Downtown

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Unit-On-Main-St-Near-Downtown.h114776148.Hotel-Information)

St. Charles Historic District

10/10

Exceptional

(7 reviews)

"The house was perfect. Clean, organized and portrayed exactly as in the pictures. We loved our stay here. The host was punctual and attentive to all questions. We would definitely stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Theresa P.

£159

includes taxes & fees

12 Feb - 13 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Unit-On-Main-St-Near-Downtown.h114776148.Hotel-Information)

![TV](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203228/dc1bb429.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203228/0f42d269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203228/48d1cc06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, desk, WiFi](https://images.trvl-media.com/lodging/93000000/92210000/92203300/92203228/33267681.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 5th Street #1 · Historic 5th Street House - Fully Rehabbed # 1

[](https://www.expedia.co.uk/St-Louis-Hotels-5th-Street-1-Historic-5th-Street-House-Fully-Rehabbed-1.h92203228.Hotel-Information)

St. Charles Historic District

9.4/10

Exceptional

(13 reviews)

"House was beautiful. Very nice quiet stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Amy S.

£177

includes taxes & fees

12 Feb - 13 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-5th-Street-1-Historic-5th-Street-House-Fully-Rehabbed-1.h92203228.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/49000000/49000000/48998600/48998582/b0517ecf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/49000000/49000000/48998600/48998582/44f61ef0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children’s area](https://images.trvl-media.com/lodging/49000000/49000000/48998600/48998582/24ad6a14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/49000000/49000000/48998600/48998582/f143485f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aspen Sights by Innsbrook Vacations!

[](https://www.expedia.co.uk/Wright-City-Hotels-Aspen-Sights-By-Innsbrook-Vacations.h48998582.Hotel-Information)

Innsbrook

9.6/10

Exceptional

(13 reviews)

"Lovely weekend- enjoyed checking out Innsbrook"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Denise L.

£164

includes taxes & fees

11 Feb - 12 Feb

[](https://www.expedia.co.uk/Wright-City-Hotels-Aspen-Sights-By-Innsbrook-Vacations.h48998582.Hotel-Information)

![2 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/110000000/109520000/109512000/109511946/189d7825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/110000000/109520000/109512000/109511946/cb34dd92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/110000000/109520000/109512000/109511946/b9af5850.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/110000000/109520000/109512000/109511946/796200a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious Townhome Retreat by StayLage

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Townhome-Retreat-By-StayLage.h109511946.Hotel-Information)

O Fallon

9.8/10

Exceptional

(10 reviews)

"Great quiet neighborhood close to everything!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jen D.

£282

includes taxes & fees

25 Feb - 26 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Townhome-Retreat-By-StayLage.h109511946.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/65000000/64400000/64396500/64396461/991db611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/65000000/64400000/64396500/64396461/5a0ca908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children’s area](https://images.trvl-media.com/lodging/65000000/64400000/64396500/64396461/01e60903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/65000000/64400000/64396500/64396461/65c699d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Ridge by Innsbrook Vacations!

[](https://www.expedia.co.uk/Wright-City-Hotels-The-Ridge-By-Innsbrook-Vacations.h64396461.Hotel-Information)

Innsbrook

9.6/10

Exceptional

(22 reviews)

"Adorable property in an amazing resort community. Beds were comfortable, house was stocked with everything we needed. Had an amazing time!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephanie S.

£453

includes taxes & fees

26 Feb - 27 Feb

[](https://www.expedia.co.uk/Wright-City-Hotels-The-Ridge-By-Innsbrook-Vacations.h64396461.Hotel-Information)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/eaf810ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/aa8990d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/d4e26647.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/95cd9c8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 4 Bedroom Wentzville Home by StayLage

[](https://www.expedia.co.uk/St-Louis-Hotels-4-Bedroom-Wentzville-Home-By-StayLage.h102252443.Hotel-Information)

Wentzville

9.8/10

Exceptional

(6 reviews)

"Amazing for attending the fireworks festivals nearby. Great shops walking distance for coffee and food"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tom K.

£364

includes taxes & fees

25 Feb - 26 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-4-Bedroom-Wentzville-Home-By-StayLage.h102252443.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/84000000/83700000/83696400/83696345/9bc90654.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/84000000/83700000/83696400/83696345/235a11cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![5 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/84000000/83700000/83696400/83696345/17d6737e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/84000000/83700000/83696400/83696345/25844b96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### VRBO Brick House of Washington

[](https://www.expedia.co.uk/Washington-Hotels-Brick-House-Of-Washington.h83696345.Hotel-Information)

Washington

10/10

Exceptional

(16 reviews)

"Beautiful, comfy, huge, amazing pool and very kind hosts. A great spot to get together with old friends and their kids of all ages."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Allison D.

£435

includes taxes & fees

12 Feb - 13 Feb

[](https://www.expedia.co.uk/Washington-Hotels-Brick-House-Of-Washington.h83696345.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/79000000/78630000/78630000/78629903/5b9a4723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV, books](https://images.trvl-media.com/lodging/79000000/78630000/78630000/78629903/62e7015d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/79000000/78630000/78630000/78629903/ecd9e83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, iron/ironing board, travel cot, WiFi](https://images.trvl-media.com/lodging/79000000/78630000/78630000/78629903/5c84f213.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful+Spacious+FencedYard🐕Grill+Patio+Walk2Park+27MileBikeTrail🚴‍♀️

[](https://www.expedia.co.uk/St-Louis-Hotels-HomeyOpenFloorPlan5TVsPatioBBQPitFencedYardBikeTrails.h78629903.Hotel-Information)

St. Peters

10/10

Exceptional

(23 reviews)

"Clean and close to everything you would want for a stay ."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Judy H.

£293

includes taxes & fees

23 Feb - 24 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-HomeyOpenFloorPlan5TVsPatioBBQPitFencedYardBikeTrails.h78629903.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/36000000/35360000/35356300/35356213/65013358.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children’s area](https://images.trvl-media.com/lodging/36000000/35360000/35356300/35356213/9299d4c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/36000000/35360000/35356300/35356213/3677b840.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/36000000/35360000/35356300/35356213/28ca12bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lake Aspen Hideaway by Innsbrook Vacations!

[](https://www.expedia.co.uk/Wright-City-Hotels-Lake-Aspen-Hideaway-By-Innsbrook-Vacations.h35356213.Hotel-Information)

Wright City

9.8/10

Exceptional

(21 reviews)

"Check-in was easy and property was clean. Great place to stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Casey A.

£164

includes taxes & fees

11 Feb - 12 Feb

[](https://www.expedia.co.uk/Wright-City-Hotels-Lake-Aspen-Hideaway-By-Innsbrook-Vacations.h35356213.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/120000000/119980000/119975900/119975875/6a214b4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/120000000/119980000/119975900/119975875/a1eeff33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Aerial view](https://images.trvl-media.com/lodging/120000000/119980000/119975900/119975875/80055f3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/120000000/119980000/119975900/119975875/daf57a27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Landing Apartments - Eureka

[](https://www.expedia.co.uk/St-Louis-Hotels-Landing-Apartments-Eureka.h119975875.Hotel-Information)

Eureka

[](https://www.expedia.co.uk/St-Louis-Hotels-Landing-Apartments-Eureka.h119975875.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/97000000/96490000/96484800/96484776/cd00dadd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96490000/96484800/96484776/0f8b26d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![4 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96490000/96484800/96484776/cc85ad9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/97000000/96490000/96484800/96484776/cf02dc30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Woodland Retreat with a Swim Spa

[](https://www.expedia.co.uk/Wright-City-Hotels-Sunflower-Valley-In-Innsbrook-Missouri-That-Sleeps-10-Comfortably-Fur-Babies-Ok.h96484776.Hotel-Information)

Innsbrook

9.6/10

Exceptional

(23 reviews)

"Plenty of room for the 6 of us "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Missy G.

£292

includes taxes & fees

11 Feb - 12 Feb

[](https://www.expedia.co.uk/Wright-City-Hotels-Sunflower-Valley-In-Innsbrook-Missouri-That-Sleeps-10-Comfortably-Fur-Babies-Ok.h96484776.Hotel-Information)

![Smart TV](https://images.trvl-media.com/lodging/115000000/114820000/114811400/114811361/3b4ea729.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/115000000/114820000/114811400/114811361/43dcbab3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/115000000/114820000/114811400/114811361/9428efb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/115000000/114820000/114811400/114811361/dcaa9c82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Cottage on Historic Main Street

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Duplex-On-Main-Street-Near-Historic-Main-Street.h114811361.Hotel-Information)

St. Charles Historic District

10/10

Exceptional

(11 reviews)

"Wonderful host and accomodations !"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Matthew K.

£156

includes taxes & fees

16 Feb - 17 Feb

[](https://www.expedia.co.uk/St-Louis-Hotels-Spacious-Duplex-On-Main-Street-Near-Historic-Main-Street.h114811361.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-24&endDate=2026-02-25&regionId=6353634&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find holiday rentals that suit your style

Private holiday homes

[](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=VACATION_HOME)

Aparthotels

[](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=APART_HOTEL)

Apartments

[](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=APARTMENT)

Cabins

[](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=CABIN)

Cottages

[](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=COTTAGE)

Condos

[](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=CONDO)

Villas

[](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=VILLA)

Chalets

[](https://www.expedia.co.uk/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America&regionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-05-11&d1=2026-05-11&endDate=2026-05-14&d2=2026-05-14&lodging=CHALET)

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## Top Defiance Hotel Reviews

![Courtyard by Marriott St Louis Creve Coeur](https://images.trvl-media.com/lodging/1000000/20000/11100/11052/96f17f89_y.jpg)

### Courtyard by Marriott St Louis Creve Coeur

10/10 Excellent

"Yes everyone was great"

[](https://expedia.co.uk/St-Louis-Hotels-Courtyard-By-Marriott-St-Louis-Creve-Coeur.h11052.Hotel-Information)

![Hollywood Casino & Hotel St. Louis](https://images.trvl-media.com/lodging/1000000/90000/82600/82568/7188325f_y.jpg)

### Hollywood Casino & Hotel St. Louis

10/10 Excellent

"Everything was very, very nice. The casino smoke was unfortunate, but was not noticable in the room, of course."

[](https://expedia.co.uk/St-Louis-Hotels-Hollywood-Casino-Hotel-St-Louis.h82568.Hotel-Information)

![Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/ad47a940_y.jpg)

### Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

10/10 Excellent

"Comfortable room "

[](https://expedia.co.uk/St-Louis-Hotels-Homewood-Suites-By-Hilton-St-Louis-Riverport-Airport-West.h1658956.Hotel-Information)

![Crowne Plaza St. Louis Airport by IHG](https://images.trvl-media.com/lodging/1000000/10000/3100/3010/45ba14e8_y.jpg)

### Crowne Plaza St. Louis Airport by IHG

10/10 Excellent

"Great place to stay "

[](https://expedia.co.uk/St-Louis-Hotels-Crowne-Plaza-St-Louis-Airport.h3010.Hotel-Information)

![Drury Plaza Hotel St. Louis Creve Coeur](https://images.trvl-media.com/lodging/1000000/80000/74700/74657/3c4503ce_y.jpg)

### Drury Plaza Hotel St. Louis Creve Coeur

10/10 Excellent

"Everything was very good. The staff, the cleanliness of the room, and the food prepared for the guests. Thank you"

[](https://expedia.co.uk/St-Louis-Hotels-Drury-Inn-Suites-St-Louis-Creve-Coeur.h74657.Hotel-Information)

![Drury Plaza Hotel St. Louis St. Charles](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/7efb516b_y.jpg)

### Drury Plaza Hotel St. Louis St. Charles

10/10 Excellent

"Location "

[](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information)

![Country Inn & Suites by Radisson, St. Charles Historic District](https://images.trvl-media.com/lodging/2000000/1340000/1330400/1330309/529fe0ff_y.jpg)

### Country Inn & Suites by Radisson, St. Charles Historic District

10/10 Excellent

"From check in my time at Country Inn was wonderful! The people are so very kind and helpful, the building is spotless, location is perfect and I had everything I needed. I recommend the Country Inn & Suites!"

[](https://expedia.co.uk/St-Louis-Hotels-Country-Inn-Suites-By-Radisson.h1330309.Hotel-Information)

![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/c42cf5fe_y.jpg)

### Ameristar Casino Resort and Spa

10/10 Excellent

"The room was great. I enjoyed my stay. "

[](https://expedia.co.uk/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information)

![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/800a6847_y.jpg)

### The Wildwood Hotel

10/10 Excellent

"Clean room and easy parking. "

[](https://expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information)

## Find out more about Defiance

**Everything you need to know about** **Defiance** **holiday rentals**

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Defiance holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Defiance holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

**Defiance holiday rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Defiance. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Defiance holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Defiance holiday rentals we have selected for you start as low as £169 per night. Entering your travel dates in the search wizard you might find even better deals!

**How to find incredible deals on Defiance rentals**

At Expedia, we put the best Defiance holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Defiance rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Defiance holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Defiance. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

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- [Isle of Wight Holiday Rentals ](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations)
- [Scarborough Holiday Rentals ](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals)
- [Edinburgh Holiday Rentals ](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals)
- [Bath Holiday Rentals ](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals)
- [Bournemouth Holiday Rentals ](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals)
- [England Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations)
- [Scotland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations)
- [Cornwall Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations)
- [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations)
- [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations)

## Frequently asked questions

### Can I find holiday rentals in Defiance?

### What are some of the best holiday rentals that Defiance has to offer?

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