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Top Holiday Rentals in Defiance

Stunning 1890's Home - Sleeps 8!

10.0 out of 10, Exceptional, (63)
"There was plenty of room to sit with friends in the living room/kitchen. Everything was clean. It was a nice convenient spot to stay! "
The price is £301
includes taxes & fees
6 Jul - 7 Jul
Stunning 1890's Home - Sleeps 8!

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

2.0 star property
7.8 out of 10, Good, (18)
"The property was quiet and as expected. They were incredibly responsive and helpful with everything. "
The price is £103
includes taxes & fees
9 Jul - 10 Jul
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

The St. Charles Guest House, lovely historic home, fun for families and groups

10.0 out of 10, Exceptional, (128)
"Annual book weekend with family. The bed downstairs was so amazing for lounging and reading all weekend. We had an amazing time! "
The St. Charles Guest House, lovely historic home, fun for families and groups

Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway

9.6 out of 10, Exceptional, (42)
"Great house. Lots of room. Walkable to main st"
The price is £263
includes taxes & fees
8 Jul - 9 Jul
Historic*Unique*Downtown*Quiet*Bright*Cheerful*Getaway

Peaceful chalet - *new* private beach, WIFI, kayaks

10.0 out of 10, Exceptional, (64)
"Excellent stay!! We couldn’t be more happy with our weekend, would recommend to anyone!"
Peaceful chalet - *new* private beach, WIFI, kayaks

Tamm Loft | River view, Downtown WashMo, Dog-friendly

10.0 out of 10, Exceptional, (5)
The price is £257
includes taxes & fees
13 Jul - 14 Jul
Tamm Loft | River view, Downtown WashMo, Dog-friendly

1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

10.0 out of 10, Exceptional, (202)
"Beautiful cottage in the perfect location. "
1830's Luxury Brick Cottage, Cozy Fireplace, right off the Cobblestone Streets!

St. Charles 1860's Gem - Sleeps 6!

9.8 out of 10, Exceptional, (104)
"Great time and nice and quiet :) "
The price is £177
includes taxes & fees
7 Jul - 8 Jul
St. Charles 1860's Gem - Sleeps 6!

The Lofts of North Main Street

9.6 out of 10, Exceptional, (139)
"This is our 2nd time staying here for a girls weekend, and it is perfect."
The price is £181
includes taxes & fees
7 Jul - 8 Jul
The Lofts of North Main Street

☆BackYard BBQ Hidden Gem☆Perfect Location~Groups /Pets Welcome

9.0 out of 10, Wonderful, (52)
"Great stay with family! "
The price is £320
includes taxes & fees
7 Jul - 8 Jul
☆BackYard BBQ Hidden Gem☆Perfect Location~Groups /Pets Welcome

Residence on the Roundabout

9.6 out of 10, Exceptional, (129)
"We had a nice stay in this cute home. St. Charles is a wonderful place to visit! "
Residence on the Roundabout

Beautiful Villa Close to All St. Louis Attractions!

9.0 out of 10, Wonderful, (52)
"Warm and cozy setting."
The price is £216
includes taxes & fees
8 Jul - 9 Jul
Beautiful Villa Close to All St. Louis Attractions!

Prime Loft of Main Street

9.8 out of 10, Exceptional, (91)
"Fantastic place and location!"
The price is £181
includes taxes & fees
7 Jul - 8 Jul
Prime Loft of Main Street

Cozy Cottage, we're told it's heavenly!

10.0 out of 10, Exceptional, (194)
"My fiancé and I had the best time during our stay! This was our second time visiting and loved it. We enjoyed relaxing on the deck and walking around the property with our pups. "
Cozy Cottage, we're told it's heavenly!

Cowboy Cabin, come sit under the trees

10.0 out of 10, Exceptional, (195)
"Me and my husband loved our little 1 year anniversary getaway. The Cabin is very cozy and in a wonderful location. You can enjoy the remoteness of the woods surrounding you but are also close enough to Washington to get out to eat if you want. Both Cabin and Cottage were very clean and wonderfully comfortable! Would 10/10 reccomend!"
Cowboy Cabin, come sit under the trees

Private Cabin on 90 Acres!

10.0 out of 10, Exceptional, (4)
"We enjoyed our stay in this peaceful cabin, the atmosphere was great for a date nite and the hot tube was very relaxing. "
Private Cabin on 90 Acres!

Luxe Innsbrook Resort Home - Lakes/Golf/Trails

9.8 out of 10, Exceptional, (16)
"House was very large and accommodated our group of 10 very well. The house had everything we needed during our stay. Access to the community pool was also nice. We would return again."
Luxe Innsbrook Resort Home - Lakes/Golf/Trails

New Listing!! Huge Custom 4-bedroom Chalet in Innsbrook Resort - Pet Friendly!

New Listing!! Huge Custom 4-bedroom Chalet in Innsbrook Resort - Pet Friendly!

The Cozy Family Retreat

8.6 out of 10, Excellent, (14)
"Great location. Was able to see the fireworks from the back yard. Clean and very modern. Overall nice place to stay."
The price is £224
includes taxes & fees
15 Jul - 16 Jul
The Cozy Family Retreat

Innsbrook Falls Hideaway - Roomy lakefront Chalet w/ spacious deck & firepit

10.0 out of 10, Exceptional, (24)
"We thoroughly enjoyed our stay at Innsbrook Falls Hideaway. The chalet was very clean and spacious for the six of us. The setting was serene and having the kayaks to explore and fish were a nice addition. The ping pong table provided extra entertainment along with the many game options that were available. The snack basket that included treats for our dog was a nice touch."
Innsbrook Falls Hideaway - Roomy lakefront Chalet w/ spacious deck & firepit
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Can I find holiday rentals in Defiance?

Yes, there are holiday rentals close to the most popular sights in Defiance, or you can select a more secluded option if you're looking for a relaxing stay. Defiance is known for its wineries and parks.

What are some of the best holiday rentals that Defiance has to offer?

St. Charles 1860's Gem - Sleeps 6!: This holiday home rental outside of Defiance is located on a river, and has a garden, a selection of books and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop.

How many holiday rentals will I find in Defiance?

With 4 Expedia holiday rentals, you're guaranteed to find just the right place for your Defiance stay.

What’s there to see and do in Defiance?

August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. Other places in town to visit include Yellow Farmhouse Winery and Chandler Hill Vineyards.

What’s a holiday rental in Defiance like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Defiance. Holiday rentals feature amenities such as hot tubs, fire pits and patios so you'll have everything you want. If you're concerned about a sanitised environment, holiday rentals can offer a sense of security away from shared hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a traditional hotel, which makes a holiday rental an attractive option for families.