Defiance Holidays
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Your Defiance Holiday
Its lively atmosphere, progressive thinking and friendly locals are among the many reasons to book a holiday package to Defiance. Whatever brings you to this rural city, you're bound to have an awesome time. If your trip to Defiance includes a little sightseeing, visit major attractions such as Chandler Hill Vineyards, Historic Daniel Boone Home and Heritage Centre and Montelle Winery. Whoever you're taking time off with and whether your budget is big or small, your ultimate Defiance holiday is just a few clicks away with Expedia.
Defiance Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
Population | 160 |
Max Temp Winter | 4ºC |
Max Temp Summer | 32ºC |
Top Sights | Augusta Winery, Chandler Hill Vineyards and Montelle Winery |
Top hotels in Defiance
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
£107
2 Sept - 3 Sept
includes taxes & fees
8.6/10 Excellent! (2,245 reviews)
"There should have been more information provided upfront, including that the room wouldn't be cleaned and no new towels until the third day of a visit, and that there would be no bottled water provided in the rooms. The soap dispensers in the shower were difficult to use and appeared to be almost ..."
Reviewed on 22 Aug 2026
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive Fenton MO
Fully refundableReserve now, pay when you stay
£80
23 Aug - 24 Aug
includes taxes & fees
Ameristar Casino Resort and Spa
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
£139
7 Sept - 8 Sept
includes taxes & fees
8.6/10 Excellent! (1,041 reviews)
"Room was a great size for the money. Hotel was clean and quiet and easy to access from the garage. Great pool as well."
Reviewed on 20 Aug 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Defiance attractions
August A. Busch Memorial Conservation Area
8.6/10 (7 reviews)
This sprawling conservation area features over 30 lakes and historic WWII bunkers amid diverse habitats. Explore well-maintained trails while watching for migratory birds and wildlife in their natural environment.
Photo by Pages of Travel
Chandler Hill Vineyards
7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
Historic Daniel Boone Home and Heritage Center
9.6/10 (4 reviews)
Step into the limestone home where Daniel Boone's son Nathan crafted a frontier masterpiece with seven fireplaces. Explore the surrounding historic village for an authentic glimpse into 19th-century pioneer life.
Sugar Creek Winery
8.0/10 (1 review)
Sip award-winning Missouri wines at this hillside vineyard along the scenic Katy Trail. Relax on covered decks with your own picnic while enjoying live weekend music and panoramic countryside views.
Yellow Farmhouse Winery
This boutique winery in Defiance, Missouri was known for its distinctive unfiltered wines and relaxed atmosphere. Visitors could enjoy tastings with live music while picnicking on scenic grounds with vineyard views.
Matson Hill Park Trailhead
Wander through 475 acres of rugged forest terrain with challenging hiking paths and gravity-flow mountain bike trails. The historic 1830s Hays Home offers a glimpse into pioneer life amid the natural splendour.
Broemmelsiek Park
This 494-acre natural playground offers nine miles of trails through forests and around serene lakes. Attend a monthly stargazing event at the astronomy viewing area for a uniquely celestial park experience.
Hamburg Trail Trailhead
This moderate 6.9-mile loop winds through the scenic Weldon Spring Conservation Area, connecting to the Katy Trail State Park. Spot native wildlife while traversing diverse landscapes of shaded woodlands and open fields.
What to do in Defiance
St. Louis Ghost Tour: Sinister Sins & Shadows
£18
per adult
100% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
£19
per adult
84% of travellers recommend
St. Louis & Gateway Arch NP Self Guided Drive & Walk Audio Tour
£13
per traveller
Frequently asked questions
How much does a Defiance travel package cost?
Our Defiance travel packages, which start at just , are the perfect way to save big bucks. All you have to do is choose your preferred flights, hotels and rental cars to create your ideal itinerary.
If I'm not able to travel, can I cancel my Defiance travel package?
Your situation can change suddenly, so yes. You may be able to cancel or alter your Defiance travel package at no cost if you've booked in the last 24 hours. For bookings older than that, you can still cancel and rebook, but your car rental company, airline or hotel may charge additional fees. Need more information? Visit our Customer Service Portal. We're here to help make sure your getaway goes off without a hitch.
How do I get a cheap travel package to Defiance?
Secure flights that fit your busy schedule, add a hotel to your booking and watch the savings grow with a Defiance travel package. It's that easy! From hotels and flights to rental cars and tours, Expedia makes travelling cheap and easy. And with more than 550 airlines and 1,000,000 properties around the globe to choose from, you'll never be short of choice.
Does Expedia offer Book Now, Pay Later Defiance holidays?
We do. Expedia has teamed up with online lender Klarna to help you conveniently pay for your holiday in manageable instalments. Simply choose the payment plan best suited to your needs during checkout and take away the stress of budgeting for your trip. Don't forget to bundle your flights, hotel and car hire with Expedia to get the biggest bang for your travel buck. Check out our flexible payment options below:
- Pay monthly holidays: Klarna offers manageable monthly payment plans that suit all types of budgets, so you can lock in that well-earned holiday sooner.
- Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay for your trip over multiple transactions.
- Low deposit holidays: Clicking the "book now" button is much easier with this plan. Just put down a small deposit on your booking and then start working on your travel plans.
Where should I stay in Defiance?
A getaway to Defiance isn't complete without seeing Sugar Creek Winery, August A. Busch Memorial Conservation Area and Chandler Hill Vineyards. Spend your nights close to these tourist attractions and make sightseeing a breeze.
What are the top hotels in Defiance?
Embassy Suites St. Louis - St. Charles and Country Inn & Suites by Radisson, St. Charles, MO are two of the most popular properties in Defiance. Why not check out the amenities and facilities at each and then make a decision?
How far in advance should I book my Defiance holiday?
It's hard to pick the perfect time for airfares, but we normally say the earlier, the better. Most international journeys on Expedia become available up to 12 months in advance. If you're booking last minute, don't despair. Cheap prices occasionally appear within a few weeks of departure dates.
What does an Expedia Defiance travel package include?
Rental cars, flights and hotels — we have them well covered. With Expedia, you can create your Defiance package the way you want. All you have to do is figure out just what you need. Once you've made your booking, you can add on extras like activities and experiences. The more you bundle, the greater the savings!
What should I know before booking a Defiance travel package?
So many places to explore, so many things to see and do. With a package, you'll be able to tick more of them off your list. Bundle your hotels, rental cars and flights and see how much you save.
Can I choose my airline with a Defiance Expedia travel package?
Yes, you're in charge. We offer more than 550 partner airlines worldwide, so you can design your Defiance trip according to your needs and budget.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
