Title: Historic Daniel Boone Home and Heritage Center in Defiance | Expedia.co.uk [Historic Daniel Boone Home and Heritage Center Hotels](https://expedia.co.uk/Historic-Daniel-Boone-Home-And-Heritage-Center-Hotels.0-l553248621532648566-0.Travel-Guide-Filter-Hotels)[Flights to Defiance](https://expedia.co.uk/Cheap-Flights-To-Defiance.d6353634.Travel-Guide-Flights)[Historic Daniel Boone Home and Heritage Center Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Historic-Daniel-Boone-Home-And-Heritage-Center.d553248621532648566.Car-Hire-Guide)[Defiance Holidays](https://expedia.co.uk/Defiance.d6353634.Holidays-City-Breaks) # Historic Daniel Boone Home and Heritage Center ## Visit Historic Daniel Boone Home and Heritage Center Activities [Defiance travel guide](https://expedia.co.uk/Defiance.dx6353634) --- --- ### Popular places to visit ![Chandler Hill Vineyards](https://images.trvl-media.com/place/553248621532648567/f82f9409-75a2-47f3-a8fc-2d7c278cc07c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Chandler Hill Vineyards You can enjoy a tasting or tour at Chandler Hill Vineyards during your travels to Defiance. While in this romantic area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Chandler-Hill-Vineyards-Defiance.d553248621532648567.Attraction) ![Wetlands landscape with a bird blind and cloudy sky reflected in a lake at the August A. Busch Memorial Conservation Area in St. Charles County Missouri](https://images.trvl-media.com/place/6160337/5138d652-49fb-41de-8fd4-a7bb27471f3e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### August A. Busch Memorial Conservation Area Explore the great outdoors at August A. Busch Memorial Conservation Area, a lovely green space in Defiance. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/August-A-Busch-Memorial-Conservation-Area-St-Louis.d6160337.Attraction) ![9-11 memorial in New York ](https://images.trvl-media.com/place/6268196/1e2df18b-5a0c-4e2a-9bc0-6956a83c47d9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 9-11 Memorial Learn about the local history of O'Fallon when you spend time at 9-11 Memorial. While in this family-friendly area, you can savour the top-notch restaurants. [](https://expedia.co.uk/9-11-Memorial-St-Louis.d6268196.Attraction) #### Matson Hill Park Trailhead You can take time to visit Matson Hill Park Trailhead during your travels to Defiance. While you're in the area, wander around the parks. [](https://expedia.co.uk/Matson-Hill-Park-Trailhead-Defiance.d641530089696399360.Attraction) #### Yellow Farmhouse Winery You can enjoy a tasting or tour at Yellow Farmhouse Winery during your travels to Defiance. While in this romantic area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Yellow-Farmhouse-Winery-Defiance.d553248621532648568.Attraction) #### Sugar Creek Winery You can enjoy a tasting or tour at Sugar Creek Winery during your travels to Defiance. While in this romantic area, you can savour the top-notch restaurants. [](https://expedia.co.uk/Sugar-Creek-Winery-Defiance.d553248621532648612.Attraction) --- ## Top Hotel Deals ## Check availability on hotels close to Historic Daniel Boone Home and Heritage Center [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532648566&startDate=2026-03-31&endDate=2026-04-01)[31 Mar - 1 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532648566&startDate=2026-03-31&endDate=2026-04-01) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532648566&startDate=2026-04-01&endDate=2026-03-02)[1 Apr - 2 Apr](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532648566&startDate=2026-04-01&endDate=2026-03-02) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.Package&adults=2&openPlayBack=true®ionId=553248621532648566&startDate=03%2F04%2F2026&endDate=05%2F04%2F2026)[3 Apr - 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O'Fallon by IHG 1175 Technology Dr O'Fallon MO [](https://expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-St-Louis-West-OFallon.h1206489.Hotel-Information) ![Staybridge Suites O'Fallon Chesterfield by IHG](https://images.trvl-media.com/lodging/2000000/1290000/1287800/1287747/71e54d85_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Staybridge Suites O'Fallon Chesterfield by IHG 1155 Technology Drive O'Fallon MO [](https://expedia.co.uk/St-Louis-Hotels-Staybridge-Suites-OFallon-Chesterfield.h1287747.Hotel-Information) ![The Wildwood Hotel](https://images.trvl-media.com/lodging/2000000/1770000/1768200/1768149/035dee6c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Wildwood Hotel 2801 Fountain Pl Wildwood MO [](https://expedia.co.uk/St-Louis-Hotels-The-Wildwood-Hotel.h1768149.Hotel-Information) ![Holiday Inn Express & Suites St. Louis - Chesterfield by IHG](https://images.trvl-media.com/lodging/24000000/23060000/23052900/23052829/5099c288_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express & Suites St. Louis - Chesterfield by IHG 11 Arnage Boulevard Chesterfield MO [](https://expedia.co.uk/St-Louis-Hotels-Holiday-Inn-Express-Suites-St-Louis-Chesterfield.h23052829.Hotel-Information) ![Drury Plaza Hotel St. Louis Chesterfield](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/69d580ec_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel St. Louis Chesterfield 355 Chesterfield Ctr Chesterfield MO [](https://expedia.co.uk/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) ![WoodSpring Suites St Peters-OFallon](https://images.trvl-media.com/lodging/109000000/108930000/108922000/108921961/20625a7b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### WoodSpring Suites St Peters-OFallon 7850 Veterans Memorial Parkway St. Peters MO [](https://expedia.co.uk/St-Louis-Hotels-Woodspring-Suites-St-Peters-Ofallon.h108921961.Hotel-Information) ![Hilton Garden Inn Chesterfield](https://images.trvl-media.com/lodging/1000000/300000/297100/297075/40ccff19_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Garden Inn Chesterfield 16631 Chesterfield Grove Ct Chesterfield MO [](https://expedia.co.uk/St-Louis-Hotels-Hilton-Garden-Inn-Chesterfield.h297075.Hotel-Information) ![Hyatt Place St. Louis/Chesterfield](https://images.trvl-media.com/lodging/7000000/6590000/6583800/6583788/8b8909bb_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt Place St. Louis/Chesterfield 333 Chesterfield Center East Chesterfield MO [](https://expedia.co.uk/St-Louis-Hotels-Hyatt-Place-St-LouisChesterfield.h6583788.Hotel-Information) [See all 1,267 properties in Historic Daniel Boone Home and Heritage Center](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=553248621532648566) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. 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