Title: All Hotels by Independent in Central San Diego - 2026 Updated Prices | Expedia.co.uk [Central San Diego Travel Guide](https://expedia.co.uk/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.co.uk/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Holiday Rentals in Central San Diego](https://expedia.co.uk/Central-San-Diego-Holiday-Rentals.d6056570.Travel-Guide-HolidayRentals)[Flights to Central San Diego](https://expedia.co.uk/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.co.uk/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-San-Diego.d6056570.Car-Hire-Guide)[Central San Diego Holidays](https://expedia.co.uk/Central-San-Diego.d6056570.Holidays-City-Breaks) ![San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels by Independent in Central San Diego from £66 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [7 Jan - 8 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2026-01-07&endDate=2026-01-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [8 Jan - 9 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2026-01-08&endDate=2026-01-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Central San Diego Independent ![Lobby](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/43ef19cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed (High Floor) | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/3d7acad3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/981f9667.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/21efa256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Legacy Resort Hotel & Spa [](https://www.expedia.co.uk/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) Mission Valley 9.2/10 Wonderful (2962) "Enjoyed my stay. Clean rooms, nice staff, will come back again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Oscar £137 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ![3 bars/lounges, lobby lounge, cocktail bar, cocktail bar](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/ce2dc6d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, minibar, desk](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/8ea4f9d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 9:00 PM, pool cabanas (surcharge)](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/83e1bd28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/fd80224d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lafayette Hotel & Club [](https://www.expedia.co.uk/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) University Heights 9.4/10 Exceptional (1391) "Amazing hotel, great staff and awesome food!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) michael £194 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/b95fa76e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot springs](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/da997a05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/72bc0145.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Atwood Hotel San Diego - SeaWorld/Zoo [](https://www.expedia.co.uk/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) Mission Valley 8.0/10 Very good (1848) "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michelle [](https://www.expedia.co.uk/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/760b1829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/edf63eff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, Non Smoking | Individually decorated, individually furnished, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/24121852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### California Suites Hotel [](https://www.expedia.co.uk/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) Clairemont 7.6/10 Good (2264) "Love the staff and the comfortable beds" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenell [](https://www.expedia.co.uk/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/8cec183d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/363afe83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/8dc04e78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Handlery Hotel [](https://www.expedia.co.uk/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) Mission Valley 8.2/10 Very good (2275) "Room and staff were excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bryant [](https://www.expedia.co.uk/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/6f47bdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/4be20fdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/bda1d22b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/17000000/16280000/16273800/16273766/ed8e473b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pleasant Inn [](https://www.expedia.co.uk/San-Diego-Hotels-Pleasant-Inn.h16273766.Hotel-Information) Clairemont 8.4/10 Very good (1294) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gene £79 includes taxes & fees 14 Jan - 15 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Pleasant-Inn.h16273766.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15860000/15857700/15857616/7e57ebb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/16000000/15860000/15857700/15857616/30b8100f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/16000000/15860000/15857700/15857616/4b694da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/16000000/15860000/15857700/15857616/af7797b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### E-Z 8 Motel Old Town [](https://www.expedia.co.uk/San-Diego-Hotels-E-Z-8-Motel-Old-Town.h15857616.Hotel-Information) Old Town San Diego 6.4/10 (2069) "Clean rooms and great staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darren [](https://www.expedia.co.uk/San-Diego-Hotels-E-Z-8-Motel-Old-Town.h15857616.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/16000000/15850000/15849600/15849536/671ff014.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gift shop](https://images.trvl-media.com/lodging/16000000/15850000/15849600/15849536/f01379a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Spa](https://images.trvl-media.com/lodging/16000000/15850000/15849600/15849536/6615bf0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15850000/15849600/15849536/09c2a34d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riverleaf Inn Mission Valley [](https://www.expedia.co.uk/San-Diego-Hotels-Riverleaf-Inn-Mission-Valley.h15849536.Hotel-Information) Mission Valley 6.4/10 (1031) "The hotel got flooded " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andy £66 includes taxes & fees 21 Jan - 22 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Riverleaf-Inn-Mission-Valley.h15849536.Hotel-Information) ![Deluxe 2 Queen with sofa sleeper | Bathroom | Combined shower/bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/b65c620d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking, Refrigerator & Microwave | In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/f6db1f6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/def5a1aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/550000/548000/547983/c47d4d2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Old Town Western Inn & Suites [](https://www.expedia.co.uk/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information) Old Town San Diego 7.6/10 Good (1009) "Clean, good staff, quiet, good location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raul [](https://www.expedia.co.uk/San-Diego-Hotels-Old-Town-Western-Inn-Suites.h547983.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/e8d02919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/b278e0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/06030fb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uptown Inn by Vantaggio - Limited Service Apart-Hotel [](https://www.expedia.co.uk/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) Hillcrest 8.4/10 Very good (271) "Overall good place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isaac £84 includes taxes & fees 13 Jan - 14 Jan [](https://www.expedia.co.uk/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-21&endDate=2026-01-22®ionId=6056570&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Hotels-Independent.0-0-d6056570--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Hotels-Independent.0-0-d6056570--bIndependent.Travel-Guide-Filter-Hotels) ## Top Central San Diego Hotel Reviews ![Hilton San Diego Mission Valley](https://images.trvl-media.com/lodging/1000000/20000/16100/16019/w5586h3835x5y5-2b129a15_y.jpg) ### Hilton San Diego Mission Valley 10/10 Excellent "The room was nice, clean, and quiet. " [](https://expedia.co.uk/San-Diego-Hotels-Hilton-San-Diego-Mission-Valley.h16019.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Breakfast is good " [](https://expedia.co.uk/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "Customer Service at front desk. I was able to check in early." [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Lafayette Hotel & Club](https://images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "The hotel is beautiful! And the diner has excellent food for very reasonable prices. The cocktails were good too! " [](https://expedia.co.uk/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![DoubleTree by Hilton San Diego - Hotel Circle](https://images.trvl-media.com/lodging/1000000/30000/25600/25536/983f923b_y.jpg) ### DoubleTree by Hilton San Diego - Hotel Circle 10/10 Excellent "Cookies at check in. Text messages asking about housekeeping" [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Hotel-Circle.h25536.Hotel-Information) ![The Atwood Hotel San Diego - SeaWorld/Zoo](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a_y.jpg) ### The Atwood Hotel San Diego - SeaWorld/Zoo 10/10 Excellent "Love staying here the crust restaurant is delicious. Rooms are comfortable and plenty of parking." [](https://expedia.co.uk/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Best hotel staff and stay " [](https://expedia.co.uk/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![Best Western Seven Seas](https://images.trvl-media.com/lodging/1000000/10000/1800/1734/w3837h2556x3y3-8b148daf_y.jpg) ### Best Western Seven Seas 10/10 Excellent "Breakfast was good and the staff was friendly and excellent. " [](https://expedia.co.uk/San-Diego-Hotels-Best-Western-Seven-Seas.h1734.Hotel-Information) ![Legacy Resort Hotel & Spa](https://images.trvl-media.com/lodging/42000000/41510000/41504800/41504735/0bbd67f4_y.jpg) ### Legacy Resort Hotel & Spa 10/10 Excellent "Full dining room service was amazing and rooms were always kept clean" [](https://expedia.co.uk/San-Diego-Hotels-Legacy-Resort-Hotel-Spa.h41504735.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - More ways to book - [Accor Hotels in Beach Cities San Diego County ](https://www.expedia.co.uk/Beach-Cities-San-Diego-County-Hotels-Accor-Hotels.0-0-d800122--bAccorHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Beach Cities San Diego County ](https://www.expedia.co.uk/Beach-Cities-San-Diego-County-Hotels-Hilton-Hotels.0-0-d800122--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Birdland Hotels ](https://www.expedia.co.uk/Birdland-San-Diego-Hotels.0-n553248635976479135-0.Travel-Guide-Filter-Hotels) - 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