Title: All Hotels by Hyatt Hotels in Central San Diego - 2026 Updated Prices | Expedia.co.uk [Central San Diego Travel Guide](https://expedia.co.uk/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.co.uk/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Holiday Rentals in Central San Diego](https://expedia.co.uk/Central-San-Diego-Holiday-Rentals.d6056570.Travel-Guide-HolidayRentals)[Flights to Central San Diego](https://expedia.co.uk/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.co.uk/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-San-Diego.d6056570.Car-Hire-Guide)[Central San Diego Holidays](https://expedia.co.uk/Central-San-Diego.d6056570.Holidays-City-Breaks) ![San Diego, California cityscape at the Gaslamp Quarter.; Shutterstock ID 446681584](https://images.trvl-media.com/place/6056570/11e424d0-560b-422b-97ab-cce270c46858.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Hotels by Hyatt Hotels in Central San Diego - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [15 Dec - 16 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2025-12-15&endDate=2025-12-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [16 Dec - 17 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2025-12-16&endDate=2025-12-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6056570&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Hotels-Hyatt-Hotels.0-0-d6056570--bHyattHotels.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Hotels-Hyatt-Hotels.0-0-d6056570--bHyattHotels.Travel-Guide-Filter-Hotels) ## Top Central San Diego Hotel Reviews ![Sheraton Mission Valley San Diego Hotel](https://images.trvl-media.com/lodging/1000000/20000/11800/11725/f387ad25_y.jpg) ### Sheraton Mission Valley San Diego Hotel 10/10 Excellent "Room very clean , staff was excellent, room service total bonus , food was great and plentiful " [](https://expedia.co.uk/San-Diego-Hotels-Sheraton-Mission-Valley-San-Diego-Hotel.h11725.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Great service " [](https://expedia.co.uk/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Hyatt Regency La Jolla](https://images.trvl-media.com/lodging/1000000/30000/21900/21891/0a66ad12_y.jpg) ### Hyatt Regency La Jolla 10/10 Excellent "Check in was great, employees were so nice" [](https://expedia.co.uk/San-Diego-Hotels-Hyatt-Regency-La-Jolla.h21891.Hotel-Information) ![San Diego Marriott La Jolla](https://images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Spacious rooms, wrap around balcony overlooking the city, comforrtable beds and close to shopping and restaurants." [](https://expedia.co.uk/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![DoubleTree by Hilton Hotel San Diego - Mission Valley](https://images.trvl-media.com/lodging/1000000/10000/400/332/8e34f752_y.jpg) ### DoubleTree by Hilton Hotel San Diego - Mission Valley 10/10 Excellent "." [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-Hotel-San-Diego-Mission-Valley.h332.Hotel-Information) ![Handlery Hotel](https://images.trvl-media.com/lodging/1000000/10000/8400/8374/ab6ccd55_y.jpg) ### Handlery Hotel 10/10 Excellent "Excellent " [](https://expedia.co.uk/San-Diego-Hotels-Handlery-Hotel.h8374.Hotel-Information) ![Days Inn by Wyndham San Diego Hotel Circle](https://images.trvl-media.com/lodging/1000000/20000/19300/19220/3334d773_y.jpg) ### Days Inn by Wyndham San Diego Hotel Circle 10/10 Excellent "Small but clean" [](https://expedia.co.uk/San-Diego-Hotels-Days-Inn-By-Wyndham-San-Diego-Hotel-Circle.h19220.Hotel-Information) ![The Atwood Hotel San Diego - SeaWorld/Zoo](https://images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a_y.jpg) ### The Atwood Hotel San Diego - SeaWorld/Zoo 10/10 Excellent "The staff, especially Annette,, is always helpful and pleasant" [](https://expedia.co.uk/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![California Suites Hotel](https://images.trvl-media.com/lodging/1000000/50000/40600/40531/4d1b251a_y.jpg) ### California Suites Hotel 10/10 Excellent "I don't remember if I saw it in the add, but if its not there please include that there is no cooking pots or pans, I thought there where since it had a stove top. Other than that, great hotel " [](https://expedia.co.uk/San-Diego-Hotels-California-Suites-Hotel.h40531.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - More ways to book - [Accor Hotels in Beach Cities San Diego County ](https://www.expedia.co.uk/Beach-Cities-San-Diego-County-Hotels-Accor-Hotels.0-0-d800122--bAccorHotels.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Beach Cities San Diego County ](https://www.expedia.co.uk/Beach-Cities-San-Diego-County-Hotels-Hilton-Hotels.0-0-d800122--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Birdland Hotels ](https://www.expedia.co.uk/Birdland-San-Diego-Hotels.0-n553248635976479135-0.Travel-Guide-Filter-Hotels) - [Motel 6 Hotels in Carlton Hills ](https://www.expedia.co.uk/Carlton-Hills-Santee-Hotels-Motel-6.0-n177695-0--bMotel6.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Carmel Valley ](https://www.expedia.co.uk/Carmel-Valley-San-Diego-Hotels-Marriott-Hotels-Resorts.0-n553248633938969513-0--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - 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