Compare and book 4 Star hotels in South San Diego, California

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Save instantly and earn perks with One Key
  • Be picky

    Search almost a million properties worldwide

Check availability on South San Diego 4 Star Hotels

Our top choices for South San Diego 4-star hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3,537 reviews)
"Great place to stay for a quick getaway!"
United States
Wilson
The price is £207
includes taxes & fees
15 Apr - 16 Apr
Hard Rock Hotel San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2,871 reviews)
"Great stay and location "
United States
Ahmad
The price is £238
includes taxes & fees
7 May - 8 May
Manchester Grand Hyatt San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.8 out of 10, Excellent, (2,543 reviews)
"Great property with great food and lots to do. "
United States
GERALD
The price is £201
includes taxes & fees
10 May - 11 May
Paradise Point Resort & Spa

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1,613 reviews)
"Beautiful hotel, friendly staff, very clean, lots to do, RedMarlin was great for breakfast. "
United States
Hanna
The price is £184
includes taxes & fees
10 May - 11 May
Hyatt Regency Mission Bay Spa and Marina

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very good, (6,150 reviews)
"Clean room and great location "
United States
Evanthia
The price is £157
includes taxes & fees
3 May - 4 May
Wyndham San Diego Bayside

San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1,665 reviews)
"Always a great stay when at this hotel "
United States
Nancy
The price is £146
includes taxes & fees
10 May - 11 May
San Diego Marriott Gaslamp Quarter

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.2 out of 10, Wonderful, (1,579 reviews)
"Everything about that stay was perfect"
United States
Victoria
The price is £213
includes taxes & fees
16 Apr - 17 Apr
Lafayette Hotel & Club

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very good, (3,467 reviews)
"Nice hotel with great location "
United States
DIANA
The price is £163
includes taxes & fees
3 May - 4 May
Sheraton San Diego Resort

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,136 reviews)
"Really enjoyed our stay there 😍"
United States
MERCEDEH
The price is £249
includes taxes & fees
15 Apr - 16 Apr
Omni San Diego Hotel at the Ballpark

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.4 out of 10, Very good, (1,398 reviews)
"The restaurant on site was delicious "
United States
Blanca
The price is £188
includes taxes & fees
10 May - 11 May
San Diego Mission Bay Resort

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,092 reviews)
"good atmosphere, good staff, friendly staff, good food, pool is amazing, restaurants are affordable and excellent."
United States
Artsrun
The price is £241
includes taxes & fees
3 May - 4 May
Marriott Marquis San Diego Marina

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1,199 reviews)
"Excellent location & great views! "
United States
Isaias
The price is £184
includes taxes & fees
8 May - 9 May
The Westin San Diego Bayview

Hotel Indigo San Diego-Gaslamp Quarter by IHG

Hotel Indigo San Diego-Gaslamp Quarter by IHG
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1,005 reviews)
"Great places to stay. Clean friendly staff will stay there again."
United States
mindi
The price is £171
includes taxes & fees
10 May - 11 May
Hotel Indigo San Diego-Gaslamp Quarter by IHG

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2,976 reviews)
"Great place to stay. "
United States
Edward
The price is £155
includes taxes & fees
27 Apr - 28 Apr
Legacy Resort Hotel & Spa

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
Downtown San Diego
9.4 out of 10, Exceptional, (828 reviews)
"Great location"
United States
Ethan
The price is £145
includes taxes & fees
10 May - 11 May
Sentral Gaslamp Quarter

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very good, (1,608 reviews)
"Great property and great experience!"
United States
Andrew
The price is £134
includes taxes & fees
26 Apr - 27 Apr
DoubleTree by Hilton Hotel San Diego - Mission Valley

Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton
4.0 star property
Historic Downtown Coronado
8.6 out of 10, Excellent, (1,012 reviews)
"Had a lovely room and the staff was very friendly. A beautiful place to stay!!!"
United States
Jewell
The price is £454
includes taxes & fees
7 May - 8 May
Hotel del Coronado, Curio Collection by Hilton

Westgate Hotel

Westgate Hotel
4.5 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1,007 reviews)
"Beautiful place "
United States
jamie
The price is £129
includes taxes & fees
10 May - 11 May
Westgate Hotel

San Diego Marriott La Jolla

San Diego Marriott La Jolla
4.0 star property
University City
8.6 out of 10, Excellent, (2,350 reviews)
"Clean, super friendly staff , great food "
United States
nancy
The price is £170
includes taxes & fees
8 May - 9 May
San Diego Marriott La Jolla

San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1,005 reviews)
"Very nice place "
United States
William
The price is £123
includes taxes & fees
3 May - 4 May
San Diego Marriott Mission Valley
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in South San Diego.
Still don't see what you're looking for?
See all properties in South San Diego.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about South San Diego

Explore the family-friendly area of South San Diego—live music, theatres and sights from Sesame Place San Diego to North Island Credit Union Amphitheatre.

Photo by Karen Leone
Open Photo by Karen Leone

Top South San Diego Hotel Reviews

Find out more about South San Diego

Frequently asked questions

What are the best 4-star hotels in South San Diego?
Based on reviews by Expedia customers, Pier South Resort, Autograph Collection by Marriott is one of the most popular in South San Diego. Featuring lots of handy amenities and an outstanding guest experience, this 4-star hotel in Imperial Beach promises an unforgettable holiday.
How much does it cost to stay in a 4-star hotel in South San Diego?
Expedia can help you easily track down the perfect 4-star hotel for your stay in South San Diego. Use our filter tool to tailor your search by things like budget, conveniences and property star rating and get access to unbeatable deals in a few clicks.

  • Search for the lowest price from £232

What's the difference between 5-star and 4-star hotels in South San Diego?
If you choose to book a stay at a 4-star hotel in South San Diego, you'll usually find lots of conveniences to make sure you're relaxed, such as a gym, restaurant and pool. You can look forward to high-quality service and upmarket accommodation. Pick a 5-star hotel and you'll have access to a few extra bells and whistles — think around-the-clock concierge, on-site spas and indulgent turndown services. You're likely to get extra amenities and first-class services at a 5-star retreat, though both are superb options for luxury travellers.

Explore a world of travel with Expedia