Key Largo Luxury Holidays

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Top flight + Luxury hotel deals in Key Largo

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Playa Largo Resort & Spa, Autograph Collection
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4 Night Luxury holidays in Key Largo

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Bayside Inn Key Largo
Amoray Dive Resort
Gilbert's Resort
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All you need to know about luxury holidays in Key Largo

What can I expect from a luxury Key Largo holiday?

Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.

How can I find all-inclusive luxury holidays in Key Largo?

Tick the all-inclusive and 5-star filters to find the crème de la crème of Key Largo holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.

Can I book a cheap luxury holiday to Key Largo?

A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to Key Largo starting at £1,110. Prices and availability are subject to change. Additional terms may apply.

Are there luxury spa holidays in Key Largo?

For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal Key Largo spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.

What should I look for when booking a luxury family holiday in Key Largo?

Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.

Can I book luxury last-minute holidays to Key Largo?

You can wangle a top-notch luxury holiday in Key Largo for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!

Can I book a luxury holiday in Key Largo with free cancellation and/or flexible dates?

If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.

Why should I book my luxury travel to Key Largo with Expedia?

Nobody does luxury quite like Expedia. With so many gorgeous properties in Key Largo to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.

Top Luxury Key Largo Hotels

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

4.5 out of 5
97450 Overseas Highway Key Largo FL
  • 14 min drive from John Pennekamp Coral Reef State Park
Stay at this luxury resort in Key Largo. Enjoy free Wi-Fi, a full-service spa and 3 restaurants. Our guests praise the helpful staff and the clean rooms in their ...
8.8/10 Excellent! (1,001 reviews)
Pool had tree debris every day. Could have been cleaner. Staff was very friendly and responsive. Suggest you look at expenses that are not disclosed when booking with Expedia. Resort fees added up quickly that were charged after check in. Room was not what we reserved on Expedia site.

Reviewed on 9 Mar 2026

Playa Largo Resort & Spa, Autograph Collection
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

2 out of 5
99340 Overseas Highway Key Largo FL
  • 9 min drive from John Pennekamp Coral Reef State Park
Stay at this beach hotel in Key Largo. Enjoy free Wi-Fi, free parking and a private beach. Our guests praise the helpful staff and the clean rooms in their reviews. ...
9/10 Wonderful! (1,015 reviews)
Our original room did not have an ocean view. When we got there we decided we would like to upgrade. They were very helpful and we ended up with the most perfect room for our stay! Old Florida feel with all the modern convenience. Staff were wonderful!

Reviewed on 10 Mar 2026

The Pelican Key Largo Cottages
Bayside Inn Key Largo

Bayside Inn Key Largo

3 out of 5
99490 Overseas Hwy Key Largo FL
  • 9 min drive from John Pennekamp Coral Reef State Park
Stay at this beach hotel in Key Largo. Enjoy free Wi-Fi, a private beach and a 24-hour fitness centre. Our guests praise the pool and the helpful staff in their ...
8.6/10 Excellent! (1,680 reviews)
Sheets and pillowcases felt dirty. Washcloths were ripped. Hotel Ran low on coffee and towels. Room wasn’t cleaned after request was made.

Reviewed on 11 Mar 2026

Bayside Inn Key Largo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.