South Region Luxury Holidays

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Top flight + Luxury hotel deals in South Region

Price found within the past 48 hours. Click for updated prices.
Hotel Saint George

Hotel Saint George

Comandante Andresito
£475
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9/10 Wonderful! (1,004 reviews)
La temperatura del agua de la piscina estaba un poco fría, por lo que no vinos huéspedes bañarse, salvo algunos niños para los cuales evidentemente el agua no estaba fría

Reviewed on 28 Sept 2026

Gran Melia Iguazú

Gran Melia Iguazú

Save 100% on your flight
£1,375
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.4/10 Exceptional! (1,003 reviews)
There isn’t a better located hotel on the Argentinian side of Iguazu Falls than Gran Melia. It is the only one inside the National park/Falls, making our visits so convenient and views from the hotel, magical. The lobby, restaurants, outdoor spaces are modern and attractive. The area that is not on par with the general spaces and price are the bedrooms (or at least the jungle level twins and king rooms). The rooms are very dated and obviously well-used. The heating didn’t work in my room and after being told it’s part of a central system twice (except my friend a few doors down had heat), they brought me a space heater. There aren’t outlets for charging devices near the beds. The bathroom is obviously old, but did have good water pressure. The beds were comfortable enough. They advertise soundproofing, but I could hear everything next door. Overall, while we found our rooms well below a 5 star caliber (barely 4), especially for the cost, we’d still do it all over again because of the convenience to the falls. Not a diss, but a learning we experienced at most hotels and people we met in Argentina. There were very few people that we could easily communicate with in English. We are in a foreign country, and it is for us to adapt so we shouldn’t expect fluency, but were surprised based on travel to 60+ countries that Argentina was more difficult than most parts of Asia, Africa, Europe etc. I understand basic Spanish and apps are great so it was all fine, just unexpected.

Reviewed on 1 Oct 2026

Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

£775
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (1,001 reviews)
A super location in a superb environment. This hotel has seen better days and it could do with an upgrade, it feels a bit 90s, especially the spa, and the in-room facilities. Definitely a nice place, but if I was the owner, I would invest a bit more, so I could remain competitive. Too many excellent hotels in the area to choose from.

Reviewed on 27 Sept 2026

Iguazú Grand Hotel

Iguazú Grand Hotel

£715
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (682 reviews)
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5* Luxury holidays in South Region

Price found within the past 48 hours. Click for updated prices.
Iguazú Grand Hotel

Iguazú Grand Hotel

£715
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (682 reviews)
Gran Melia Iguazú

Gran Melia Iguazú

Save 100% on your flight
£1,375
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.4/10 Exceptional! (1,003 reviews)
There isn’t a better located hotel on the Argentinian side of Iguazu Falls than Gran Melia. It is the only one inside the National park/Falls, making our visits so convenient and views from the hotel, magical. The lobby, restaurants, outdoor spaces are modern and attractive. The area that is not on par with the general spaces and price are the bedrooms (or at least the jungle level twins and king rooms). The rooms are very dated and obviously well-used. The heating didn’t work in my room and after being told it’s part of a central system twice (except my friend a few doors down had heat), they brought me a space heater. There aren’t outlets for charging devices near the beds. The bathroom is obviously old, but did have good water pressure. The beds were comfortable enough. They advertise soundproofing, but I could hear everything next door. Overall, while we found our rooms well below a 5 star caliber (barely 4), especially for the cost, we’d still do it all over again because of the convenience to the falls. Not a diss, but a learning we experienced at most hotels and people we met in Argentina. There were very few people that we could easily communicate with in English. We are in a foreign country, and it is for us to adapt so we shouldn’t expect fluency, but were surprised based on travel to 60+ countries that Argentina was more difficult than most parts of Asia, Africa, Europe etc. I understand basic Spanish and apps are great so it was all fine, just unexpected.

Reviewed on 1 Oct 2026

Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

£775
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (1,001 reviews)
A super location in a superb environment. This hotel has seen better days and it could do with an upgrade, it feels a bit 90s, especially the spa, and the in-room facilities. Definitely a nice place, but if I was the owner, I would invest a bit more, so I could remain competitive. Too many excellent hotels in the area to choose from.

Reviewed on 27 Sept 2026

Don't see what you're looking for?
See all available trips from Buenos Aires to South Region
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4 Night Luxury holidays in South Region

Price found within the past 48 hours. Click for updated prices.
Hotel Saint George

Hotel Saint George

Comandante Andresito
£475
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9/10 Wonderful! (1,004 reviews)
La temperatura del agua de la piscina estaba un poco fría, por lo que no vinos huéspedes bañarse, salvo algunos niños para los cuales evidentemente el agua no estaba fría

Reviewed on 28 Sept 2026

Gran Melia Iguazú

Gran Melia Iguazú

Save 100% on your flight
£1,375
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.4/10 Exceptional! (1,003 reviews)
There isn’t a better located hotel on the Argentinian side of Iguazu Falls than Gran Melia. It is the only one inside the National park/Falls, making our visits so convenient and views from the hotel, magical. The lobby, restaurants, outdoor spaces are modern and attractive. The area that is not on par with the general spaces and price are the bedrooms (or at least the jungle level twins and king rooms). The rooms are very dated and obviously well-used. The heating didn’t work in my room and after being told it’s part of a central system twice (except my friend a few doors down had heat), they brought me a space heater. There aren’t outlets for charging devices near the beds. The bathroom is obviously old, but did have good water pressure. The beds were comfortable enough. They advertise soundproofing, but I could hear everything next door. Overall, while we found our rooms well below a 5 star caliber (barely 4), especially for the cost, we’d still do it all over again because of the convenience to the falls. Not a diss, but a learning we experienced at most hotels and people we met in Argentina. There were very few people that we could easily communicate with in English. We are in a foreign country, and it is for us to adapt so we shouldn’t expect fluency, but were surprised based on travel to 60+ countries that Argentina was more difficult than most parts of Asia, Africa, Europe etc. I understand basic Spanish and apps are great so it was all fine, just unexpected.

Reviewed on 1 Oct 2026

Loi Suites Iguazú Hotel

Loi Suites Iguazú Hotel

£775
per person
7 Nov - 11 Nov
found 1 hour ago
Return flight included
Buenos Aires (BUE) to Iguazu (IGR)
9.2/10 Wonderful! (1,001 reviews)
A super location in a superb environment. This hotel has seen better days and it could do with an upgrade, it feels a bit 90s, especially the spa, and the in-room facilities. Definitely a nice place, but if I was the owner, I would invest a bit more, so I could remain competitive. Too many excellent hotels in the area to choose from.

Reviewed on 27 Sept 2026

Don't see what you're looking for?
See all available trips from Buenos Aires to South Region
View all trips

All you need to know about luxury holidays in South Region

What can I expect from a luxury South Region holiday?

Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes.

How can I find all-inclusive luxury holidays in South Region?

Tick the all-inclusive and 5-star filters to find the crème de la crème of South Region holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end.

Can I book a cheap luxury holiday to South Region?

A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to South Region starting at £475. Prices and availability are subject to change. Additional terms may apply.

Are there luxury spa holidays in South Region?

For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal South Region spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh.

What should I look for when booking a luxury family holiday in South Region?

Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore.

Can I book luxury last-minute holidays to South Region?

You can wangle a top-notch luxury holiday in South Region for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better!

Can I book a luxury holiday in South Region with free cancellation and/or flexible dates?

If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions.

Why should I book my luxury travel to South Region with Expedia?

Nobody does luxury quite like Expedia. With so many gorgeous properties in South Region to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book.

Top Luxury South Region Hotels

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR
Stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff and the property condition ...
10/10 Exceptional! (1,000 reviews)
"If you're visiting the Brazilian side of Iguaçu, the ONLY reason not to stay here is price, as it is beyond many peoples' budgets. Otherwise, it's perfect: a gorgeous hotel in an unbeatable location directly across from the falls. We could see the falls from our room! Also, you are allowed to stay ..."

Reviewed on 1 Oct 2026

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Iguazú Grand Hotel

Iguazú Grand Hotel

Route 12 Km 1640 Puerto Iguazú Misiones
Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...
Iguazú Grand Hotel
Gran Melia Iguazú

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones
Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...
9.4/10 Exceptional! (1,001 reviews)
"There isn’t a better located hotel on the Argentinian side of Iguazu Falls than Gran Melia. It is the only one inside the National park/Falls, making our visits so convenient and views from the hotel, magical. The lobby, restaurants, outdoor spaces are modern and attractive. The area that is not ..."

Reviewed on 1 Oct 2026

Gran Melia Iguazú
See all 12,675 properties in South Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.