Title: Samos Prefecture Luxury Holidays 2026 | Expedia.co.uk ![](https://images.trvl-media.com/place/3216/93fc981d-adf5-4f8c-9d0c-fe06476028ce.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Samos Prefecture Luxury Holidays ## Book a Luxury Hotel + Flight or Car together to unlock savings Photo by Erica Previtali - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top flight + Luxury hotel deals in Samos Prefecture Price found within the past 48 hours. Click for updated prices. ![Arion Hotel](https://images.trvl-media.com/lodging/3000000/2810000/2806500/2806447/cf9b035b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Arion Hotel £499 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 9.2/10 Wonderful! (72 reviews) Great location. Breathtaking views. Lovely helpful friendly staff. Compliment with Covid safety regulations. Would defenitly visit again. Reviewed on 24 Aug 2020 ![Doryssa Seaside Resort](https://images.trvl-media.com/lodging/1000000/590000/583300/583244/9e8b6e3a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Doryssa Seaside Resort £584 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 8.6/10 Excellent! (153 reviews) nice and relaxing hotel very close to Pythagoreio center. Reviewed on 8 Jun 2025 ![Casa Cook Samos](https://images.trvl-media.com/lodging/73000000/72990000/72988800/72988785/b89cb141_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Cook Samos £736 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 9.6/10 Exceptional! (95 reviews) Clean and modernly decorated rooms with all the facilities Reviewed on 31 Oct 2025 ![Doryssa Theorem Hotel](https://images.trvl-media.com/lodging/91000000/90870000/90861800/90861756/fb6ac4e4_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Doryssa Theorem Hotel £530 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 9.6/10 Exceptional! (81 reviews) Absolutely wonderful hotel - wish we could have stayed longer. Perfect location, beautiful room, breakfast was delicious and staff very helpful. Highly recommend. Reviewed on 8 Oct 2025 ![Hydrele Beach Hotel](https://images.trvl-media.com/lodging/49000000/48920000/48911600/48911595/fbe46700_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hydrele Beach Hotel £526 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 8.6/10 Excellent! (40 reviews) Nice facilities. Very helpful and pleasant staff. Reviewed on 11 Sept 2025 Don't see what you're looking for? See all available trips from London to Samos Prefecture [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2026-04-10/2026-04-17/?FromAirport=LON&Destination=SMI&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 5\* Luxury holidays in Samos Prefecture Price found within the past 48 hours. Click for updated prices. ![Proteas Blu Resort - Adults Only](https://images.trvl-media.com/lodging/4000000/3580000/3579900/3579852/04fcce4a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Proteas Blu Resort - Adults Only £577 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 9.4/10 Exceptional! (86 reviews) Love this hotel! The beach is fantastic and the views are incredible. Definitely would book again. Reviewed on 2 Sept 2025 ![Doryssa Seaside Resort](https://images.trvl-media.com/lodging/1000000/590000/583300/583244/9e8b6e3a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Doryssa Seaside Resort £584 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 8.6/10 Excellent! (153 reviews) nice and relaxing hotel very close to Pythagoreio center. Reviewed on 8 Jun 2025 ![Casa Cook Samos](https://images.trvl-media.com/lodging/73000000/72990000/72988800/72988785/b89cb141_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Cook Samos £736 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 9.6/10 Exceptional! (95 reviews) Clean and modernly decorated rooms with all the facilities Reviewed on 31 Oct 2025 Don't see what you're looking for? See all available trips from London to Samos Prefecture [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2026-04-10/2026-04-17/?FromAirport=LON&Destination=SMI&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 4 Night Luxury holidays in Samos Prefecture Price found within the past 48 hours. Click for updated prices. ![So Nice Hotel](https://images.trvl-media.com/lodging/11000000/10570000/10568800/10568768/474d31f1_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### So Nice Hotel £426 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 9.4/10 Exceptional! (29 reviews) The hotel rooms are very nice size. I had an efficiency kitchen in there that was fully equipped. Room service was fantastic. Reviewed on 27 Aug 2024 ![Doryssa Seaside Resort](https://images.trvl-media.com/lodging/1000000/590000/583300/583244/9e8b6e3a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Doryssa Seaside Resort £584 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 8.6/10 Excellent! (153 reviews) nice and relaxing hotel very close to Pythagoreio center. Reviewed on 8 Jun 2025 ![Ino Hotel & Suites](https://images.trvl-media.com/lodging/1000000/890000/881600/881511/a5f3656f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Ino Hotel & Suites £550 per person 21 May - 24 May found 1 day ago Return direct flight included London (LON) to Samos (SMI) 8.6/10 Excellent! (114 reviews) Friendly staff and great view! Reviewed on 28 Aug 2025 Don't see what you're looking for? See all available trips from London to Samos Prefecture [View all trips](https://expedia.co.uk/go/package/search/FlightHotel/2026-04-10/2026-04-17/?FromAirport=LON&Destination=SMI&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## All you need to know about luxury holidays in Samos Prefecture #### What can I expect from a luxury Samos Prefecture holiday? Luxury on holiday is all about relaxing and feeling good. Whether you choose a sumptuous spa, Michelin-starred restaurant or super-king bed is your call. Use our amenities filters to find the things that tick all your boxes. #### How can I find all-inclusive luxury holidays in Samos Prefecture? Tick the all-inclusive and 5-star filters to find the crème de la crème of Samos Prefecture holidays. With everything included in the package price, you can drink and dine to your heart’s content, without worrying about that bill at the end. #### Can I book a cheap luxury holiday to Samos Prefecture? A luxury holiday doesn’t have to break the bank. Travel out of peak season, choose a hotel or resort a little way out or go for a last-minute getaway and you’ll find some cracking deals. Sort by price to find luxury holidays to Samos Prefecture starting at £426\. Prices and availability are subject to change. Additional terms may apply. #### Are there luxury spa holidays in Samos Prefecture? For sunset massages on the shoreline and view-filled saunas, use our spa filter to find your ideal Samos Prefecture spa hotel. Book a whole weekend soaking away your stresses, or hop into the spa after the beach, some golf or a local advent-ahhhh. #### What should I look for when booking a luxury family holiday in Samos Prefecture? Luxury isn’t just for adults. Those little touches designed for little people make a family holiday genuinely stress free … which is the greatest luxury of all. Look for spacious suites, pools toddlers can splash in, and breakfast buffets with waffles, pancakes and Nutella galore. #### Can I book luxury last-minute holidays to Samos Prefecture? You can wangle a top-notch luxury holiday in Samos Prefecture for a fraction of the normal price by booking last minute. Just enter your dates and see what’s available – if you’re flexible ... even better! #### Can I book a luxury holiday in Samos Prefecture with free cancellation and/or flexible dates? If you’re splashing out on a luxury holiday, make sure your money is safe by booking with free cancellation. Just use the fully refundable filter and make sure you read all the terms and conditions. #### Why should I book my luxury travel to Samos Prefecture with Expedia? Nobody does luxury quite like Expedia. With so many gorgeous properties in Samos Prefecture to choose from, as well as access to first-class flight deals and hire cars with horsepower, there’s no better place to book. ## More holidays you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holiday packages](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### Top Luxury Holiday Destinations > - 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Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app