Title: Cheap Flights from San Francisco to Knoxville (SFO to TYS) - Expedia.co.uk ![Skyline of downtown Knoxville, Tennessee, USA](https://images.trvl-media.com/place/602977/e5dfacc8-29fe-4ae7-93f0-6aa1cd8e604b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/602977/e5dfacc8-29fe-4ae7-93f0-6aa1cd8e604b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Cheap Flights from San Francisco (SFO) to Knoxville (TYS) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from San Francisco International Airport (SFO) to Alcoa - Knoxville Airport (TYS) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:tys,departure:30/10/2025TANYT&leg2=from:tys,to:sfo,departure:06/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:tys,departure:30/10/2025TANYT&leg2=from:tys,to:sfo,departure:06/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:tys,departure:30/10/2025TANYT&leg2=from:tys,to:sfo,departure:06/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![Frontier Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg) Frontier Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:tys,departure:30/10/2025TANYT&leg2=from:tys,to:sfo,departure:06/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:tys,departure:30/10/2025TANYT&leg2=from:tys,to:sfo,departure:06/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) - ![Alaska Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg) Alaska Airlines [](https://www.expedia.co.uk/Flights-Search?leg1=from:sfo,to:tys,departure:30/10/2025TANYT&leg2=from:tys,to:sfo,departure:06/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Find the cheapest month to fly from San Francisco (SFO) to Knoxville (TYS) ### January is typically the cheapest month to fly From £117 - £400 per traveller. ## Frequently asked questions ### How much is a flight from SFO to McGhee Tyson Airport (TYS)? > Within the past 7 days on Expedia, for flights departing within the next year, the lowest price quoted for a round-trip journey from San Francisco Airport to McGhee Tyson Airport (TYS) was . Fares this good don't wait forever, so make sure you book yours today. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from San Francisco Intl. Airport (SFO) to Knoxville Airport? > Most flights can be cancelled online, but whether or not you incur a fee differs between airlines. If you do need to cancel your trip, follow the instructions in the [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033). ### How do I find cheap flights from SFO to Knoxville Airport that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for SFO to TYS flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from SFO to McGhee Tyson Airport (TYS)? > The flight distance from San Francisco to Alcoa is 3,400 kilometres. Bring a drink, a few snacks and a laptop filled with movies. Keep yourself entertained and the time will fly by. ### Which airlines fly direct from San Francisco Intl. Airport (SFO) to Knoxville Airport? > You won't find any airlines flying directly between San Francisco Airport and TYS, so be prepared to make at least one stop on your journey. A layover can be a good way to break up a trip! ### Are San Francisco Intl. Airport (SFO) to TYS flight tickets cheaper when they're purchased at the last minute? > Booking your trip from San Francisco Intl. Airport (SFO) to Knoxville Airport at the last minute could be your ticket to a great deal. However, it might cost you a whole lot more! If you'd prefer not to take the risk, book well ahead of your departure date. In fact, Expedia has some of the biggest bargains as far ahead as 12 months in advance. If your preferred carrier hasn't released tickets yet, check back regularly as deals are updated on Expedia all the time. ## Travel information | Origin airport | San Francisco Intl. | | --- | --- | | Destination airport | McGhee Tyson | | Distance | 3385 km | | Average flight time | 7 hours 1 min | ## Book with confidence ### Compare flights from San Francisco to Knoxville easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from San Francisco to Knoxville. Operating between them flights per day, airlines cover the route. And fly direct, getting you to McGhee Tyson in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from San Francisco Intl. to McGhee Tyson.   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from San Francisco Intl. (SFO) to McGhee Tyson (TYS) The easiest way to view the best deals on flights from San Francisco to Knoxville today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from San Francisco Intl. to McGhee Tyson start at just and range up to .   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near San Francisco and Knoxville - booking your flight during , the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your San Francisco to Knoxville flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from San Francisco Intl. to McGhee Tyson for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [4 Star Hotels in West Knoxville](https://www.expedia.co.uk/4Star-West-Knoxville-Hotels.s40-0-d6059852.Travel-Guide-Filter-Hotels) - [Hotels with Indoor Pools in Alcoa](https://www.expedia.co.uk/Alcoa-Hotels-Hotels-With-Indoor-Pools.0-0-d5985-tHotelswithIndoorPools.Travel-Guide-Filter-Hotels) - [Alcoa Hotels](https://www.expedia.co.uk/Alcoa-Hotels.d5985.Travel-Guide-Hotels) - [Clover Hill Hotels](https://www.expedia.co.uk/Clover-Hill-Hotels.d177642.Travel-Guide-Hotels) - [Concord Hotels](https://www.expedia.co.uk/Concord-Hotels.d177828.Travel-Guide-Hotels) - [Louisville Hotels](https://www.expedia.co.uk/Louisville-Hotels.d6139365.Travel-Guide-Hotels) - [Caravan Parks in Maryville](https://www.expedia.co.uk/Maryville-Caravan-Parks.d8649-aaCaravanParks.Travel-Guide-Accommodation) - 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