A tower with a spherical top, fireworks in the sky, and a cityscape with buildings and a tented area.

Cheap Flights from New Orleans (MSY) to Knoxville (TYS)

Popular airlines from Louis Armstrong New Orleans Intl. Airport (MSY) to Alcoa - Knoxville Airport (TYS)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 25% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Find the cheapest month to fly from New Orleans (MSY) to Knoxville (TYS)

September is typically the cheapest month to fly

From £145 - £282 per traveller.

Frequently asked questions

How much does a flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson) cost?
You can find one-way and return flights from MSY to TYS with Expedia. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see our cheapest fares first, and use the Price Tracking tool to receive alerts when MSY to TYS ticket fares go up or down.
What is the cheapest month to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
If you're looking for the cheapest time to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson), January is typically your best bet. You can expect average return fares to be around £259 during this month. January often sees lower prices because it falls after the busy holiday travel season, when demand for flights tends to decrease. Other budget-friendly months for this route include February and May.
Which airlines fly direct from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
Enter MSY to TYS and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
Frontier Airlines offers one of the cheapest connecting return flights from Louis Armstrong New Orleans Intl. (MSY) to McGhee Tyson (TYS) starting from around £200. American Airlines is one of the cheapest airlines offering nonstop return flights from Louis Armstrong New Orleans Intl. (MSY) to McGhee Tyson (TYS), with tickets starting from around £814 for flights that can be booked for departure within the next year. These prices are per adult, for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from New Orleans, LA (MSY) to Knoxville, TN (TYS)?
To find a cheap flight from New Orleans, LA (MSY) to Knoxville, TN (TYS), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from New Orleans, LA (MSY) to Knoxville, TN (TYS)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
The earliest flight from Louis Armstrong New Orleans Intl. (MSY) to McGhee Tyson (TYS) typically departs around 5:00 AM. This flight is operated by United and is a seasonal service, active in March and April. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
How long does it take to fly from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson)?
There are no nonstop flights from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson). This route covers a distance of around 872 kilometers. Flights with one stop typically take around 5 hours 18 minutes. If your journey involves two or more stops, you can expect the travel time to be longer, usually around 9 hours. Keep in mind that actual flight times can vary due to factors like routing, weather, and wind patterns.
Can you fly business or first class from New Orleans, LA (MSY) to Knoxville, TN (TYS)?
Select the "Business class" and "First class" filters when looking for New Orleans, LA (MSY) to Knoxville, TN (TYS) flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight with Expedia?
It's easy to earn miles on a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Knoxville, TN (TYS) from New Orleans, LA (MSY)?
If you're planning to travel to Knoxville from Louis Armstrong New Orleans Intl. (MSY), you can fly directly into McGhee Tyson Airport (TYS). Some flights may connect through major hubs like Dallas-Fort Worth Intl. (DFW), Miami Intl. (MIA), or Austin-Bergstrom Intl. (AUS) before reaching Knoxville. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson) at the last minute?
Typically, booking a last minute flight from New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight and hotel package?
Securing a New Orleans, LA (MSY-Louis Armstrong New Orleans Intl.) to Knoxville, TN (TYS-McGhee Tyson) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from New Orleans, LA (MSY) to Knoxville, TN (TYS)?
If you booked your New Orleans, LA (MSY) to Knoxville, TN (TYS) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Louis Armstrong New Orleans Intl.
Destination airport
McGhee Tyson
Distance
867 km

Book with confidence

Compare flights from New Orleans to Knoxville easily and book with confidence

For travelling on business or for pleasure, Expedia makes it easy to book your flights from New Orleans to Knoxville. Operating between them flights per day, airlines cover the route. And fly direct, getting you to McGhee Tyson in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Louis Armstrong New Orleans Intl. to McGhee Tyson.  

To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights. 

Grab a great deal on your flight from Louis Armstrong New Orleans Intl. (MSY) to McGhee Tyson (TYS)

The easiest way to view the best deals on flights from New Orleans to Knoxville today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Louis Armstrong New Orleans Intl. to McGhee Tyson start at just and range up to .  

To find an even better deal, try  

  • being flexible on your dates – midweek flights can be cheaper
  • looking for other airports near New Orleans and Knoxville
  • booking your flight during , the cheapest month on this route
  • varying your flight times – early morning and late at night are sometimes cheaper 

Why you should book your New Orleans to Knoxville flight with Expedia!

We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Louis Armstrong New Orleans Intl. to McGhee Tyson for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.  

Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.  

Compare flights from New Orleans to Knoxville easily and book with confidence

Explore a world of travel with Expedia

*Available to Expedia members.