Title: £232 Cheap Flights from Panama City to Santa Cruz (PTY to VVI) - Expedia.co.uk ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # £232 Cheap Flights from Panama City (PTY) to Santa Cruz (VVI) [View £232 flight on Sat, 25 Oct 2025](https://expedia.co.uk/Flights-Search?trip=oneway&leg1=from:PTY,to:VVI,departure:25/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:231.10&airProductToken=AQpkCjAIwawBEgI1ORjvxAEgwTMo36b7AjC4p_sCOFNAAFgBagVCQVNJQ3IIU0VPQjBCUjkKMAjBrAESAzE2NxjBMyC1RSiWrPsCMIuu-wI4U0ABWAFqBUJBU0lDcghTRU9CMEJSORIKCAIQARgCKgJBVhgBIgQIARABKAIoAygEMAE) - [Return](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Tocumen Intl. Airport (PTY) to Santa Cruz (VVI-Viru Viru Intl.) - ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:vvi,departure:07/11/2025TANYT&leg2=from:vvi,to:pty,departure:14/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.co.uk/Flights-Search?leg1=from:pty,to:vvi,departure:07/11/2025TANYT&leg2=from:vvi,to:pty,departure:14/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 25% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.co.uk/login) ## Cheap Flights from Panama City (PTY) to Santa Cruz (VVI) Prices were available within the past 7 days and start at £232 for one-way flights and £494 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Return ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Tue, 7 Jul - Mon, 13 Jul PTY Panama City VVI Santa Cruz £494 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:07/07/2026TANYT&leg2=from:VVI,to:PTY,departure:13/07/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:494.00&airProductToken=AQpkCjAIwawBEgI1NxjvxAEgwTMomeGRAzD34ZEDOFBAAFgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAzE2NxjBMyC1RSju65EDMN7tkQM4UEABWAFqBUJBU0lDcghQRU9CMEJSQgpmCjAIwawBEgMxNjYYtUUgwTMon5uSAzCUnZIDOFNAAFgBagVCQVNJQ3IIU0VPQjBCUjkKMgjBrAESBDgzODAYwTMg78QBKJuekgMwjp-SAzhTQAFYAWoFQkFTSUNyCFNFT0IwQlI5EgoIAhABGAIqAkFWGAEiBAgBEAEoAigDKAQwAQ) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Thu, 13 Nov - Sat, 10 Jan PTY Panama City VVI Santa Cruz £496 Return found 23 hours ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:13/11/2025TANYT&leg2=from:VVI,to:PTY,departure:10/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:495.40&airProductToken=AQpkCjAIwawBEgI1NxjvxAEgwTMomoD9AjD-gP0COFNAAFgBagVCQVNJQ3IIU0VPQjBCUjkKMAjBrAESAzE2NxjBMyC1RSj2gf0CMOuD_QI4U0ABWAFqBUJBU0lDcghTRU9CMEJSOQpkCjAIwawBEgMxNjYYtUUgwTMozIWCAzC3h4IDOFBAAFgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAjQwGMEzIO_EASiVj4IDMIiQggM4UEABWAFqBUJBU0lDcghQRU9CMEJSQhIKCAIQARgCKgJBVhgBIgQIARABKAIoAygEMAE) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, 12 Apr - Sun, 19 Apr PTY Panama City VVI Santa Cruz £498 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:12/04/2026TANYT&leg2=from:VVI,to:PTY,departure:19/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:497.60&airProductToken=AQozCjEIw5oBEgMyMjEY78QBILVFKMOZigMw8JuKAzhMQABYAWoFQkFTSUNyCExMQThNWTJTCjMKMQjDmgESAzEyNhi1RSDvxAEom96KAzC84IoDOEVAAFgBagVCQVNJQ3IIRUxBMk1ZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Thu, 9 Apr - Thu, 16 Apr PTY Panama City VVI Santa Cruz £514 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:09/04/2026TANYT&leg2=from:VVI,to:PTY,departure:16/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:513.70&airProductToken=AQozCjEIw5oBEgMxMjcY78QBILVFKLT1iQMw6veJAzhFQABYAWoFQkFTSUNyCEVMQTJNWTJTCjMKMQjDmgESAzEyNhi1RSDvxAEou7yKAzDcvooDOEVAAFgBagVCQVNJQ3IIRUxBMk1ZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Sun, 2 Nov - Sun, 9 Nov PTY Panama City VVI Santa Cruz £534 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:02/11/2025TANYT&leg2=from:VVI,to:PTY,departure:09/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:533.60&airProductToken=AQpkCjAIwawBEgI0MRjvxAEgwTMou_37AjCk_vsCOFBAAFgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAzE2NxjBMyC1RSiWhvwCMIuI_AI4UEABWAFqBUJBU0lDcghQRU9CMEJSQgpkCjAIwawBEgMxNjYYtUUgwTMojMz8AjD3zfwCOFBAAFgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAjU2GMEzIO_EASjL0PwCMLTR_AI4UEABWAFqBUJBU0lDcghQRU9CMEJSQhIKCAIQARgCKgJBVhgBIgQIARABKAIoAygEMAE) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Wed, 12 Nov - Tue, 6 Jan PTY Panama City VVI Santa Cruz £535 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:12/11/2025TANYT&leg2=from:VVI,to:PTY,departure:06/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:534.70&airProductToken=AQpkCjAIwawBEgI1NxjvxAEgwTMo__T8AjDe9fwCOFBAAFgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAzE2NxjBMyC1RSjW9vwCMMv4_AI4UEABWAFqBUJBU0lDcghQRU9CMEJSQgpkCjAIwawBEgMxNjYYtUUgwTMozNiBAzC32oEDOFBAAFgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAjYwGMEzIO_EASiw3oEDMKPfgQM4UEABWAFqBUJBU0lDcghQRU9CMEJSQhIKCAIQARgCKgJBVhgBIgQIARABKAIoAygEMAE) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Thu, 9 Apr - Thu, 16 Apr PTY Panama City VVI Santa Cruz £537 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:09/04/2026TANYT&leg2=from:VVI,to:PTY,departure:16/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:536.10&airProductToken=AQpkCjAIwawBEgI1NxjvxAEgwTMo-feJAzDX-IkDOFBAAFgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAzE2NxjBMyC1RSjOgooDML6EigM4UEABWAFqBUJBU0lDcghQRU9CMEJSQgpkCjAIwawBEgMxNjYYtUUgwTMon72KAzCUv4oDOFBAAFgBagVCQVNJQ3IIUEVPQjBCUkIKMAjBrAESAjU2GMEzIO_EASi5xYoDMKLGigM4UEABWAFqBUJBU0lDcghQRU9CMEJSQhIKCAIQARgCKgJBVhgBIgQIARABKAIoAygEMAE) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, 2 Nov - Sun, 9 Nov PTY Panama City VVI Santa Cruz £576 Return found 3 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:02/11/2025TANYT&leg2=from:VVI,to:PTY,departure:09/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:575.20&airProductToken=AQozCjEIw5oBEgMyMjEY78QBILVFKKOG_AIwyIj8AjhPQABYAWoFQkFTSUNyCE9MQTdNWTJTCjMKMQjDmgESAzEyNhi1RSDvxAEo9cr8AjCczfwCOE9AAFgBagVCQVNJQ3IIT0xBN01ZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Tue, 7 Jul - Mon, 13 Jul PTY Panama City VVI Santa Cruz £614 Return found 1 day ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:07/07/2026TANYT&leg2=from:VVI,to:PTY,departure:13/07/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:613.90&airProductToken=AQpoCjIIwawBEgI1NxjvxAEgwTMomeGRAzD34ZEDOFBAAFgBagdDTEFTU0lDcghQRU9CMkJSQgoyCMGsARIDMTY3GMEzILVFKO7rkQMw3u2RAzhQQAFYAWoHQ0xBU1NJQ3IIUEVPQjJCUkIKagoyCMGsARIDMTY2GLVFIMEzKJ-bkgMwlJ2SAzhTQABYAWoHQ0xBU1NJQ3IIU0VPQjJCUjkKNAjBrAESBDgzODAYwTMg78QBKJuekgMwjp-SAzhTQAFYAWoHQ0xBU1NJQ3IIU0VPQjJCUjkSCggBEAEYASoCQVYYASIECAEQASgCKAMoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, 12 Apr - Sun, 19 Apr PTY Panama City VVI Santa Cruz £618 Return found 6 days ago [](https://expedia.co.uk/Flights-Search?trip=roundtrip&leg1=from:PTY,to:VVI,departure:12/04/2026TANYT&leg2=from:VVI,to:PTY,departure:19/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:617.50&airProductToken=AQo1CjMIw5oBEgMyMjEY78QBILVFKMOZigMw8JuKAzhMQABYAWoHQ0xBU1NJQ3IITExBOE1ZMU4KNQozCMOaARIDMTI2GLVFIO_EASib3ooDMLzgigM4RUAAWAFqB0NMQVNTSUNyCEVMQTJNWTFOEgoIARABGAEqAkNNGAEiBAgBEAEoAigDKAQwAQ) ## Frequently asked questions ### How much is a flight from Panama Airport to Viru Viru Intl. Airport (VVI)? > Within the past 7 days on Expedia, for flights departing within the next year, the lowest price available for a round-trip journey from PTY to Viru Viru was £494. Fares this cheap don't hang around, so book yours today. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Tocumen Intl. Airport (PTY) to VVI? > Every air carrier has its own terms and conditions. If you do decide to cancel, follow the easy instructions on our [Customer Service Portal](https://www.expedia.co.uk/service/?langid=1033). ### How do I find cheap flights from Tocumen Intl. Airport (PTY) to VVI that have flexible change policies? > Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for Panama Airport to VVI flights, you'll see a "no change fees" filter for you to select. ### How far is the flight from PTY to Viru Viru? > It's around 3,500 kilometres between Tocumen and Santa Cruz, so expect to be flying for a while. Keep yourself occupied with things like playing cards (if you're travelling with friends) or the latest bestseller. ### Which airlines fly direct from PTY to VVI? > If you want to fly directly from PTY to VVI, Copa Airlines (CM) is a great option. It operates 47 flights every month between Tocumen and Santa Cruz. ### Are Tocumen Intl. Airport (PTY) to Viru Viru Intl. Airport (VVI) flight tickets cheaper when they're purchased at the last minute? > It is possible to find an awesome last-minute deal from PTY to VVI, but it's also possible to miss out entirely! As many airlines release prices up to a year in advance, it's worth keeping an eye on fares early and being ready to pounce when you see a good bargain. Expedia compares air carrier prices and updates flight deals frequently, so you can feel confident knowing you're always getting the latest offers. ## Travel information | Origin airport | Tocumen Intl. | | --- | --- | | Destination airport | Viru Viru Intl. | | Airlines serving | Copa, avianca | | Return price | £494 | | Distance | 3445 km | | Average flight time | 5 hours 56 mins | ## Book with confidence ### Compare flights from Panama City to Santa Cruz easily and book with confidence For travelling on business or for pleasure, Expedia makes it easy to book your flights from Panama City to Santa Cruz. Operating between them flights per day, 20 airlines cover the route. And fly direct, getting you to Viru Viru Intl. in just hours. If you have a preferred carrier, use our advanced search tool to find the right flight from Tocumen Intl. to Viru Viru Intl..   To make things even better, in the advanced search, you can also choose to fly economy, premium economy, business or first class, select your maximum number of stops, and pick your preferred departure and arrival time. You can also opt for refundable and direct flights.  Grab a great deal on your flight from Tocumen Intl. (PTY) to Viru Viru Intl. (VVI) The easiest way to view the best deals on flights from Panama City to Santa Cruz today is to enter your travel dates and hit search. From here, you can sort your results by price to see the cheapest flights first. Right now, return flights from Tocumen Intl. to Viru Viru Intl. start at just £494 and range up to £618.   To find an even better deal, try   - being flexible on your dates – midweek flights can be cheaper - looking for other airports near Panama City and Santa Cruz - booking your flight during July, the cheapest month on this route - varying your flight times – early morning and late at night are sometimes cheaper  Why you should book your Panama City to Santa Cruz flight with Expedia! We cater for all flight types, cabin classes and airlines. So whether you’re booking flights from Tocumen Intl. to Viru Viru Intl. for a budget break or a business trip with a bit of pleasure thrown in, we make it easy to secure the seat that’s right for you.   Thanks to our supersized inventory that offers great choice all in one place, you know you’ll get a great deal with Expedia. Especially if you bundle your flight together with your hotel, you will unlock amazing savings. For added peace of mind, you can choose flexible bookings or filter to find refundable options, so you won’t pay a fee to change your flight.   ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Holiday Homes - [5 Star Hotels in Colinas del Urubo](https://www.expedia.co.uk/5Star-Colinas-Del-Urubo-Hotels.s50-0-d6349680.Travel-Guide-Filter-Hotels) - [Colinas del Urubo Hotels](https://www.expedia.co.uk/Colinas-Del-Urubo-Hotels.d6349680.Travel-Guide-Hotels) - [Santa Cruz Hotels](https://www.expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Hotel-Destinations) - [La Belgica Hotels](https://www.expedia.co.uk/La-Belgica-Hotels.d6350205.Travel-Guide-Hotels) - [Apartments in Santa Cruz](https://www.expedia.co.uk/Santa-Cruz-Apartments.d6053940-aaApartments.Travel-Guide-Accommodation) - [Adults Only Resorts & in Santa Cruz](https://www.expedia.co.uk/Santa-Cruz-Hotels-Adults-Only-Resorts.0-0-d6053940-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Santa Cruz](https://www.expedia.co.uk/Santa-Cruz-Hotels-Beach-Hotels.0-0-d6053940-tBeachHotels.Travel-Guide-Filter-Hotels) - 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[Flights to Santa Cruz](https://www.expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights) - [Flights to Santa Cruz](https://www.expedia.co.uk/Destinations-In-Santa-Cruz.d6297178.Flight-Destinations) - [Flights from Wanigela (AGL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/agl/srz/wanigela-to-santa-cruz) - [Flights from Antalaha (ANM) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/anm/srz/antalaha-to-santa-cruz) - [Flights from Artigas (ATI) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/ati/srz/artigas-to-santa-cruz) - [Flights from Altamira (ATM) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/atm/srz/altamira-to-santa-cruz) - [Flights from Alexandria (AXN) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/axn/srz/alexandria-to-santa-cruz) - [Flights from Hartford (BDL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/bdl/srz/hartford-to-santa-cruz) - [Flights from Bereina (BEA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/bea/srz/bereina-to-santa-cruz) - [Flights from Beirut (BEY) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/bey/srz/beirut-to-santa-cruz) - [Flights from Belfast (BHD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/bhd/srz/belfast-to-santa-cruz) - [Flights from Bournemouth (BOH) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/boh/srz/bournemouth-to-santa-cruz) - [Flights from Boston (BOS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/bos/srz/boston-to-santa-cruz) - [Flights from Brussels (BRU) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/bru/srz/brussels-to-santa-cruz) - [Flights from Bata (BSG) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/bsg/srz/bata-to-santa-cruz) - [Flights from Buenos Aires (BUE) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/bue/srz/buenos-aires-to-santa-cruz) - [Flights from Bonito (BYO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/byo/srz/bonito-to-santa-cruz) - [Flights from Cagliari (CAG) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/cag/srz/cagliari-to-santa-cruz) - [Flights from Camiri (CAM) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/cam/srz/camiri-to-santa-cruz) - [Flights from Guangzhou (CAN) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/can/srz/guangzhou-to-santa-cruz) - [Flights from Cochabamba (CBB) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/cbb/srz/cochabamba-to-santa-cruz) - [Flights from Paris (CDG) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/cdg/srz/paris-to-santa-cruz) - [Flights from Central (CEM) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/cem/srz/central-to-santa-cruz) - [Flights from Cobija (CIJ) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/cij/srz/cobija-to-santa-cruz) - [Flights from Charlotte (CLT) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/clt/srz/charlotte-to-santa-cruz) - [Flights from Ciudad Del Carmen (CME) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/cme/srz/ciudad-del-carmen-to-santa-cruz) - [Flights from Copiapo (CPO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/cpo/srz/copiapo-to-santa-cruz) - [Flights from Dhahran (DHA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/dha/srz/dhahran-to-santa-cruz) - [Flights from The Dalles (DLS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/dls/srz/the-dalles-to-santa-cruz) - [Flights from Derby (DRB) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/drb/srz/derby-to-santa-cruz) - [Flights from Dublin (DUB) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/dub/srz/dublin-to-santa-cruz) - [Flights from Dubai (DXB) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/dxb/srz/dubai-to-santa-cruz) - [Flights from Flores (FRS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/frs/srz/flores-to-santa-cruz) - [Flights from Gaya (GAY) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/gay/srz/gaya-to-santa-cruz) - [Flights from Rio de Janeiro (GIG) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/gig/srz/rio-de-janeiro-to-santa-cruz) - [Flights from Isla Baltra (GPS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/gps/srz/isla-baltra-to-santa-cruz) - [Flights from Gatokae (GTA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/gta/srz/gatokae-to-santa-cruz) - [Flights from Freetown (HGS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/hgs/srz/freetown-to-santa-cruz) - [Flights from Frankfurt (HHN) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/hhn/srz/frankfurt-to-santa-cruz) - [Flights from Khajuraho (HJR) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/hjr/srz/khajuraho-to-santa-cruz) - [Flights from Takaka (KTF) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/ktf/srz/takaka-to-santa-cruz) - [Flights from Las Vegas (LAS) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/las/srz/las-vegas-to-santa-cruz) - [Flights from London (LHR) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/lhr/srz/london-to-santa-cruz) - [Flights from Ljubljana (LJU) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/lju/srz/ljubljana-to-santa-cruz) - [Flights from Madrid (MAD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/mad/srz/madrid-to-santa-cruz) - [Flights from Orlando (MCO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/mco/srz/orlando-to-santa-cruz) - [Flights from Managua (MGA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/mga/srz/managua-to-santa-cruz) - [Flights from Nuremberg (NUE) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/nue/srz/nuremberg-to-santa-cruz) - [Flights from Oakland (ODM) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/odm/srz/oakland-to-santa-cruz) - [Flights from Orlando (ORL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/orl/srz/orlando-to-santa-cruz) - [Flights from Panama City (PAC) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/pac/srz/panama-city-to-santa-cruz) - [Flights from Punta Islita (PBP) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/pbp/srz/punta-islita-to-santa-cruz) - [Flights from Potosi (POI) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/poi/srz/potosi-to-santa-cruz) - [Flights from Panama City (PTY) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/pty/srz/panama-city-to-santa-cruz) - [Flights from Puerto Vallarta (PVR) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/pvr/srz/puerto-vallarta-to-santa-cruz) - [Flights from Dallas (RBD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/rbd/srz/dallas-to-santa-cruz) - [Flights from Resende (REZ) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/rez/srz/resende-to-santa-cruz) - [Flights from Riberalta (RIB) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/rib/srz/riberalta-to-santa-cruz) - [Flights from San Diego (SAN) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/san/srz/san-diego-to-santa-cruz) - [Flights from Santa Ana del Yacuma (SBL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sbl/srz/santa-ana-del-yacuma-to-santa-cruz) - [Flights from Stockton (SCK) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sck/srz/stockton-to-santa-cruz) - [Flights from Santiago (SCL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/scl/srz/santiago-to-santa-cruz) - [Flights from San Francisco (SFO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sfo/srz/san-francisco-to-santa-cruz) - [Flights from Springfield (SGF) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sgf/srz/springfield-to-santa-cruz) - [Flights from San Juan (SJU) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sju/srz/san-juan-to-santa-cruz) - [Flights from Salt Lake City (SLC) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/slc/srz/salt-lake-city-to-santa-cruz) - [Flights from Santa Maria (SMX) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/smx/srz/santa-maria-to-santa-cruz) - [Flights from Alcantarí Intl. Airport (SRE) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/sre/srz/sucre-to-santa-cruz) - [Flights from Sydney (SYD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/syd/srz/sydney-to-santa-cruz) - [Flights from Trinidad (TDD) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tdd/srz/trinidad-to-santa-cruz) - [Flights from Tarija (TJA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tja/srz/tarija-to-santa-cruz) - [Flights from Tsushima (TSJ) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tsj/srz/tsushima-to-santa-cruz) - [Flights from Lake Tahoe (TVL) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/tvl/srz/lake-tahoe-to-santa-cruz) - [Flights from Ulaangom (ULO) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/ulo/srz/ulaangom-to-santa-cruz) - [Flights from Upolu Point (UPP) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/upp/srz/upolu-point-to-santa-cruz) - [Flights from Veracruz (VER) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/ver/srz/veracruz-to-santa-cruz) - [Flights from Van Nuys (VNY) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/vny/srz/van-nuys-to-santa-cruz) - [Flights from Mayo (YMA) to Santa Cruz (SRZ)](https://www.expedia.co.uk/lp/flights/yma/srz/mayo-to-santa-cruz) - [Visit Colinas del Urubo](https://www.expedia.co.uk/Colinas-Del-Urubo.dx6349680) - [Ethno-Folkloric Museum](https://www.expedia.co.uk/Ethno-Folkloric-Museum-Santa-Cruz.d6098834.Attraction) - [Visit La Belgica](https://www.expedia.co.uk/La-Belgica.dx6350205) - [Santa Cruz Holidays](https://www.expedia.co.uk/Santa-Cruz.d6053940.Holidays-City-Breaks) - [Visit Santa Cruz](https://www.expedia.co.uk/Santa-Cruz.dx6053940) - [Warnes Holidays](https://www.expedia.co.uk/Warnes.d6352296.Holidays-City-Breaks) - [Warnes Holiday Rentals](https://www.expedia.co.uk/Warnes-Holiday-Rentals.d6352296.Travel-Guide-HolidayRentals) \*Available to Expedia members.