£348 Cheap Flights from Chicago (ORD) to Panama City (PTY)

View £348 flight on Sun, 24 May 2026Opens in a new window

Popular airlines from Chicago O'Hare International Airport (ORD) to Tocumen Intl. Airport (PTY)

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Cheap Flights from Chicago (ORD) to Panama City (PTY)

Prices were available within the past 7 days and start at £348 for one-way flights and £545 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Thu, 14 May - Thu, 21 May
ORD
Chicago
PTY
Panama City
£545 Return, found 17 hours ago
£545
Return
found 17 hours ago
Select avianca flight, departing Thu, 14 May from Chicago to Panama City, returning Thu, 21 May, priced at £545 found 17 hours ago
avianca
Sat, 16 May - Thu, 4 Jun
ORD
Chicago
PTY
Panama City
£546 Return, found 1 day ago
£546
Return
found 1 day ago
Select avianca flight, departing Sat, 16 May from Chicago to Panama City, returning Thu, 4 Jun, priced at £546 found 1 day ago
avianca
Sat, 16 May - Thu, 4 Jun
ORD
Chicago
PTY
Panama City
£554 Return, found 1 day ago
£554
Return
found 1 day ago
Select avianca flight, departing Sat, 16 May from Chicago to Panama City, returning Thu, 4 Jun, priced at £554 found 1 day ago
avianca
Sat, 16 May - Thu, 4 Jun
ORD
Chicago
PTY
Panama City
£555 Return, found 1 day ago
£555
Return
found 1 day ago
Select avianca flight, departing Sat, 16 May from Chicago to Panama City, returning Thu, 4 Jun, priced at £555 found 1 day ago
avianca
Fri, 15 May - Fri, 22 May
ORD
Chicago
PTY
Panama City
£562 Return, found 17 hours ago
£562
Return
found 17 hours ago
Select avianca flight, departing Fri, 15 May from Chicago to Panama City, returning Fri, 22 May, priced at £562 found 17 hours ago
avianca
Sat, 16 May - Thu, 4 Jun
ORD
Chicago
PTY
Panama City
£563 Return, found 1 day ago
£563
Return
found 1 day ago
Select avianca flight, departing Sat, 16 May from Chicago to Panama City, returning Thu, 4 Jun, priced at £563 found 1 day ago
avianca
Sat, 16 May - Thu, 4 Jun
ORD
Chicago
PTY
Panama City
£586 Return, found 1 day ago
£586
Return
found 1 day ago
Select avianca flight, departing Sat, 16 May from Chicago to Panama City, returning Thu, 4 Jun, priced at £586 found 1 day ago
avianca
Sun, 17 May - Sun, 24 May
ORD
Chicago
PTY
Panama City
£594 Return, found 17 hours ago
£594
Return
found 17 hours ago
Select avianca flight, departing Sun, 17 May from Chicago to Panama City, returning Sun, 24 May, priced at £594 found 17 hours ago
Copa
Sat, 16 May - Thu, 4 Jun
ORD
Chicago
PTY
Panama City
£638 Return, found 1 day ago
£638
Return
found 1 day ago
Select Copa flight, departing Sat, 16 May from Chicago to Panama City, returning Thu, 4 Jun, priced at £638 found 1 day ago
Aeromexico
Mon, 13 Jul - Fri, 17 Jul
ORD
Chicago
PTY
Panama City
£1,106 Return, found 1 day ago
£1,106
Return
found 1 day ago
Select Aeromexico flight, departing Mon, 13 Jul from Chicago to Panama City, returning Fri, 17 Jul, priced at £1,106 found 1 day ago

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Tocumen Intl. PTY. Cheapest option available. Average driving time to city centre is 16 minutes. Flights from £545
PTY
Tocumen Intl.
Cheapest
Average driving time to city centre16 min
Flights from £545

Find the cheapest month to fly from Chicago (ORD) to Panama City (PTY)

May is typically the cheapest month to fly

From £255 - £525 per traveller.

Frequently asked questions

How much is a flight from ORD to Tocumen Intl. Airport (PTY)?
Pack your bags, because round-trip journeys from O'Hare Intl. Airport (ORD) to Panama Airport start from £545. That's based on fares advertised within the last 7 days on Expedia for flights departing within the next year. Prices can go up quickly, so book today to get the best deal. Prices and availability are subject to change. Additional terms apply.
Do I need to pay a cancellation fee if I cancel my flight from ORD to Panama Airport?
This varies from airline to airline, as each has its own terms and conditions. Head to the Customer Service Portal, where you'll find easy instructions on how to cancel online.
How do I find cheap flights from ORD to PTY that have flexible change policies?
Many airlines offer the option to reschedule your flight without a change fee. All you pay is the difference between the original flight and the new flight. When you're searching for O'Hare Airport to Panama Airport flights, you'll see a "no change fees" filter for you to select.
How far is the flight from O'Hare Airport to PTY?
Around 3,800 kilometres separates Chicago and Tocumen, so pack something to keep you occupied for a few hours. That gripping novel you haven't had time to start will be perfect.
Which airlines fly direct from O'Hare Airport to Panama Airport?
A favourite with many frequent flyers, Copa Airlines (CM) operates 30 flights every month from ORD to PTY. Pick the one that fits with your travel plans and book your ticket today.
Are ORD to Panama Airport flight tickets cheaper when they're purchased at the last minute?
Flight tickets from O'Hare Intl. Airport (ORD) to Tocumen Intl. Airport (PTY) are available up to a year before departure on Expedia. And although you may occasionally nab great last-minute deal, it's never a sure thing. Also, booking your flights in advance means you'll have more options — and you can avoid landing the dreaded middle seat! We frequently update our fares to bring you the biggest bargains, so check back often for all the latest specials.

Frequently asked questions

Which airlines fly direct from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
Enter ORD to PTY and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
To find a cheap flight from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
The best airline to fly with from Chicago, IL (ORD-O'Hare Intl.) (ORD) to Panama City (PTY-Tocumen Intl.) (PTY) will differ from traveller to traveller. If you like to fly early, CM offers early morning flights. If price is the most important factor, CM typically offers the lowest fares. UA offers the most daily flights from Chicago, IL (ORD-O'Hare Intl.) (ORD) to Panama City (PTY-Tocumen Intl.) (PTY), which is brilliant if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
When flying from Chicago O'Hare International (ORD) to Panama City Tocumen International (PTY), you'll find approximately 2 nonstop flights per day. For even more choice, look at flights that include layovers, as there are around 112 connecting flights daily. Some common connection points include El Dorado International (BOG), George Bush Intercontinental (IAH), and Pearson International (YYZ).
What is the earliest flight from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
The earliest flight from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.) typically departs at approximately 12:00 AM local time, operated by American Airlines. This is a seasonal service active in December. An early departure like this can help maximise your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
You'll typically find the most flights from Chicago O'Hare International Airport (ORD) to Panama City Tocumen International Airport (PTY) on a Thursday, with around 50 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include United Airlines, American Airlines, and Delta Air Lines. Flight schedules are consistent throughout the week.
What are the most popular departure times for flights from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
The most popular departure times for flights from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.) are in the early morning, from 6am to 9am. About 41% of passengers prefer this time. Many major carriers, including Copa Airlines, United Airlines and American Airlines, offer flights during this window. This timing works well because you can start your journey bright and early, arriving in Panama City with plenty of time to settle in.
How long does it take to fly from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
Flying nonstop from ORD to PTY takes around 5 hours 20 minutes, with the route covering approximately 2,332 miles. Flights with a layover typically take 3 hours 30 minutes longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
Select the "Business class" and "First class" filters when looking for ORD to PTY flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.) flight with Expedia?
It's easy to earn miles on a Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Panama City from O'Hare Intl. (ORD)?
From O'Hare Intl. (ORD), you can fly into Northwest Florida Beaches Intl. (ECP) and Tocumen Intl. (PTY) in Panama City. Some flights may connect through major hubs like Detroit Metropolitan Wayne County (DTW), Indianapolis Intl. (IND), Nashville Intl. (BNA) before reaching Panama City. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.) at the last minute?
Typically, booking a last minute flight from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.) flight and hotel package?
Securing a Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.)?
If you booked your Chicago, IL (ORD-O'Hare Intl.) to Panama City (PTY-Tocumen Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
O'Hare Intl.
Destination airport
Tocumen Intl.
Airlines serving
Aeromexico, Copa, avianca
Return price
£545
Distance
3731 km
Average flight time
5 hours 26 mins

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