Title: TOP Luxury Hotels in Vatican, Rome for 2026 - Vatican Upscale Hotels | Expedia.co.uk [Vatican Travel Guide](https://expedia.co.uk/Rome-Vatican.dx6046253)[Holiday Rentals in Rome](https://expedia.co.uk/Rome-Holiday-Rentals.d179899.Travel-Guide-HolidayRentals)[Flights to Rome](https://expedia.co.uk/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.co.uk/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Vatican Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Vatican.d6046253.Car-Hire-Guide)[Vatican Holidays](https://expedia.co.uk/Vatican.d6046253.Holidays-City-Breaks) ![Rome, Vatican city; Shutterstock ID 364719503](https://images.trvl-media.com/place/6046253/267902cf-6b70-47a3-a839-10db3dc044c9.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Vatican, Rome - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Vatican Luxury Hotels Tonight [10 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6046253&startDate=2026-01-10&endDate=2026-01-11&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [11 Jan - 12 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6046253&startDate=2026-01-11&endDate=2026-01-12&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6046253&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) In two weeks [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6046253&startDate=2026-01-23&endDate=2026-01-25&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Vatican luxury hotels ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4470000/4464300/4464282/522f2437.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4470000/4464300/4464282/8d857537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Suite (Spa Access) | Egyptian cotton sheets, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/5000000/4470000/4464300/4464282/beba5662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/5000000/4470000/4464300/4464282/6ac7f70e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Agrippina Gran Meliá - The Leading Hotels of the World [](https://www.expedia.co.uk/Rome-Hotels-Villa-Agrippina-Gran-Melia-The-Leading-Hotels-Of-The-World.h4464282.Hotel-Information) Rome City Centre 9.2/10 Wonderful (937 reviews) "Beautiful hotel, very clean, staff so friendly and helpful Would definitely stay again!" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) debra jane £397 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Rome-Hotels-Villa-Agrippina-Gran-Melia-The-Leading-Hotels-Of-The-World.h4464282.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/77000000/76770000/76764600/76764503/609d2355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/77000000/76770000/76764600/76764503/a2ab338e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, River View | View from room](https://images.trvl-media.com/lodging/77000000/76770000/76764600/76764503/5ff5c76e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/77000000/76770000/76764600/76764503/92e7672f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The First Musica - Preferred Hotels & Resorts [](https://www.expedia.co.uk/Rome-Hotels-The-First-Musica.h76764503.Hotel-Information) Rome City Centre 9.6/10 Exceptional (105 reviews) "Hotel and Team was great... I'll go back definitively! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Juan £294 includes taxes & fees 29 Jan - 30 Jan [](https://www.expedia.co.uk/Rome-Hotels-The-First-Musica.h76764503.Hotel-Information) ![Signature Suite, 1 Bedroom | Hypo-allergenic bedding, free minibar items, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/530000/526300/526245/80c27ad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Suite, 1 Bedroom, City View | Living area | LCD TV](https://images.trvl-media.com/lodging/1000000/530000/526300/526245/6f63f4d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served, Italian cuisine](https://images.trvl-media.com/lodging/1000000/530000/526300/526245/dcd7d663.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Triple Room | Hypo-allergenic bedding, free minibar items, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/530000/526300/526245/0c5ed9e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Le Méridien Visconti Rome [](https://www.expedia.co.uk/Rome-Hotels-Le-Meridien-Visconti-Rome.h526245.Hotel-Information) Rome City Centre 8.8/10 Excellent (1,000 reviews) "Great hotel, convenient location." ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Edgar £195 includes taxes & fees 22 Jan - 23 Jan [](https://www.expedia.co.uk/Rome-Hotels-Le-Meridien-Visconti-Rome.h526245.Hotel-Information) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2260000/2256300/2256299/4bcdfad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2260000/2256300/2256299/76d8c6e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/3000000/2260000/2256300/2256299/4172d20c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2260000/2256300/2256299/w3840h2559x0y3-f602203e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### NH Collection Roma Giustiniano [](https://www.expedia.co.uk/Rome-Hotels-NH-Collection-Roma-Giustiniano.h2256299.Hotel-Information) Rome City Centre 8.8/10 Excellent (1,001 reviews) "Everything else and I had the best croissant for breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tet £161 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Rome-Hotels-NH-Collection-Roma-Giustiniano.h2256299.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/68000000/67360000/67355000/67354985/6a755918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/68000000/67360000/67355000/67354985/9f2abacf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/68000000/67360000/67355000/67354985/569c09ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/68000000/67360000/67355000/67354985/e03140d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Orazio Palace Hotel [](https://www.expedia.co.uk/Rome-Hotels-Orazio-Palace-Hotel.h67354985.Hotel-Information) Rome City Centre 9.4/10 Exceptional (233 reviews) "Breakfast is really good with various of options, staff are nice and welcoming " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Fan £149 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Rome-Hotels-Orazio-Palace-Hotel.h67354985.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/1000000/70000/63400/63399/db6d1bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/1000000/70000/63400/63399/bf5757f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/63400/63399/fcb5764d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (EUR 18.00 per person)](https://images.trvl-media.com/lodging/1000000/70000/63400/63399/460c48f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Dei Mellini [](https://www.expedia.co.uk/Rome-Hotels-Hotel-Dei-Mellini.h63399.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,002 reviews) "Great place to stay and close to everything " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Recoldemon £172 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Rome-Hotels-Hotel-Dei-Mellini.h63399.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/abfd2e6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/6432bb9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast buffet](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/c12cb945.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/60cb2e91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Isa [](https://www.expedia.co.uk/Rome-Hotels-Hotel-Isa.h856829.Hotel-Information) Rome City Centre 9.4/10 Exceptional (1,009 reviews) "Great stay at Hotel Isa over New Years. The location was convenient, staff was " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £146 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Rome-Hotels-Hotel-Isa.h856829.Hotel-Information) ![2 restaurants, pizza](https://images.trvl-media.com/lodging/65000000/64600000/64593200/64593148/bfde70a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/65000000/64600000/64593200/64593148/d55ab16f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna](https://images.trvl-media.com/lodging/65000000/64600000/64593200/64593148/f1c48906.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, pizza](https://images.trvl-media.com/lodging/65000000/64600000/64593200/64593148/4608bf7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mama Shelter Roma [](https://www.expedia.co.uk/Rome-Hotels-Mama-Shelter-Roma.h64593148.Hotel-Information) Vatican 9.0/10 Wonderful (911 reviews) "Great stay. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Joey £145 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Rome-Hotels-Mama-Shelter-Roma.h64593148.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/90000/83600/83532/70689d18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/90000/83600/83532/88f5065b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/90000/83600/83532/f686360f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/90000/83600/83532/af894127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Spring House Hotel Rome Vatican, Tapestry Collection Hilton [](https://www.expedia.co.uk/Rome-Hotels-The-Spring-House-Hotel-Rome-Vatican.h83532.Hotel-Information) Rome City Centre 9.2/10 Wonderful (1,003 reviews) "I had a wonderful stay at this hotel. The staff was very friendly and helpful, the room was clean and comfortable, the location it was perfect for visiting Vatican City Sistine Chapel and the Vatican Museum. I would definitely stay here again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) magda £124 includes taxes & fees 12 Jan - 13 Jan [](https://www.expedia.co.uk/Rome-Hotels-The-Spring-House-Hotel-Rome-Vatican.h83532.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/46000000/45410000/45407000/45406906/8b8f029a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/46000000/45410000/45407000/45406906/df28a843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/46000000/45410000/45407000/45406906/7de567ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Bathroom | Shower, hydromassage showerhead, free toiletries, hair dryer](https://images.trvl-media.com/lodging/46000000/45410000/45407000/45406906/f8db7c94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apollo Boutique Hotel [](https://www.expedia.co.uk/Rome-Hotels-Apollo-Boutique-Hotel.h45406906.Hotel-Information) Vatican 9.2/10 Wonderful (122 reviews) "Staff was excellent. Would recommend." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andres [](https://www.expedia.co.uk/Rome-Hotels-Apollo-Boutique-Hotel.h45406906.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-24&endDate=2026-01-25®ionId=6046253&adults=2&sort=LUXURY&star=40,50&openPlayBack=true) ## Find out more about Vatican ### Vaticanand its attractions for luxury travelers For luxury travellers seeking an exquisite stay in the Vatican neighbourhood, the allure of the iconic St. Peter's Basilica is undeniable. Just a short walk from your hotel, this stunning architectural masterpiece offers awe-inspiring views from its dome, where you can soak in the breathtaking panorama of the city. Another must-visit is the Vatican Museums, home to the magnificent Sistine Chapel; imagine exploring these hallowed halls early in the morning, before the crowds, perhaps with a private guided tour that delves into the rich history and artistry within. For a taste of local culture, the charming Borgo Pio street features quaint boutiques and gourmet restaurants, perfect for a leisurely stroll or a romantic dinner. Don't miss a visit to the tranquil Vatican Gardens, where you can enjoy a serene escape amidst meticulously landscaped grounds, available through exclusive guided tours. After a day of exploring, retreat to your opulent hotel, such as the luxurious Hotel de Russie, where you can unwind in a sumptuous spa or enjoy a cocktail on the terrace with views of the bustling piazza. Here, attentive service ensures a pampered experience, making your stay as memorable as the sights themselves. ### Find the best luxury hotels and resorts in Vatican For those seeking an opulent experience in the Vatican, these luxurious hotels combine exquisite amenities and prime locations to create unforgettable stays. [**Casa Mia Vaticano Guest House**](https://www.expedia.co.uk/Rome-Hotels-Casa-Mia-Vaticano.h13198352.Hotel-Information) - **Why it's great for a luxury retreat:** Casa Mia Vaticano Guest House is a luxurious retreat with an exceptional review rating of 9.8, perfect for travellers seeking comfort and sophistication. The hotel features premium bedding and Frette Italian sheets, elevating the sleeping experience to one of indulgence. With a dedicated concierge service, guests can expect personalized attention throughout their stay, making it a truly exclusive experience. - **Other amenities:** This guest house includes a kitchenette for added convenience, along with a balcony for guests to enjoy the stunning views. Daily housekeeping and free toiletries further enhance the comfort of each stay. The hotel also offers various parking options, including free nearby parking, and 24-hour airport shuttle services to accommodate travel needs. Additional amenities such as eco-friendly cups and onsite babysitting services cater to a well-rounded luxury experience. - **Neighborhood:** Vatican - **Nearby attractions:** St. Peter's Square - 1.6 km, St. Peter's Basilica - 1.5 km, Sistine Chapel - 1.7 km [**Leonardo Da Vinci Guest House**](https://www.expedia.co.uk/Rome-Hotels-Leonardo-Da-Vinci-Guest-House.h16328381.Hotel-Information) - **Why it's great for a luxury retreat:** With an outstanding review rating of 9.8, Leonardo Da Vinci Guest House is a luxurious retreat that promises comfort and elegance. The guesthouse features premium bedding and Egyptian cotton sheets, ensuring a restful night’s sleep. Its sophisticated atmosphere and attentive service cater to every need, making it an ideal choice for travellers seeking a refined experience in the Vatican area. - **Other amenities:** Guests at this guesthouse can enjoy convenient onsite shopping and early check-in options for a straightforward arrival. The hotel also offers daily housekeeping, ensuring that every detail is meticulously attended to. With a variety of parking options available, including onsite, nearby, and street parking, guests can explore the city with ease. Additionally, the guesthouse provides airport transportation and shuttles for seamless travel to and from the airport. - **Neighborhood:** Vatican - **Nearby attractions:** St. Peter's Square - 1 km, St. Peter's Basilica - 0.9 km, Sistine Chapel - 1.1 km [**New Design St. Peter**](https://www.expedia.co.uk/Rome-Hotels-New-Design-St-Peter.h12625682.Hotel-Information) - **Why it's great for a luxury retreat:** New Design St. Peter boasts a remarkable review rating of 9.4, making it a luxurious choice for guests looking to immerse themselves in the elegance of the Vatican. This stylish hotel offers premium bedding and designer decor that create an inviting atmosphere for relaxation. The onsite shopping adds an exclusive touch, allowing guests to indulge without leaving the hotel. - **Other amenities:** This hotel features a private hot tub for ultimate relaxation, along with traditional hotel design elements that enhance its charm. Guests can take advantage of the 24-hour airport shuttle service, ensuring convenient access to and from the airport. Additional offerings include free toiletries, daily housekeeping, and flexible check-in and check-out options. The hotel also provides gardens and snack bar facilities to complement a pleasant stay in the heart of Rome. - **Neighborhood:** Vatican - **Nearby attractions:** St. Peter's Square - 1.1 km, Castel Sant'Angelo - 1.5 km, Sistine Chapel - 1.5 km [**Mama Shelter Roma**](https://www.expedia.co.uk/Rome-Hotels-Mama-Shelter-Roma.h64593148.Hotel-Information) - **Why it's great for a luxury retreat:** Mama Shelter Roma stands out as a luxurious haven for travelers, earning an impressive guest review rating of 9.0\. This chic hotel offers an array of high-end amenities, including a serene spa with full-service options, an indoor pool, and a rooftop terrace that invites relaxation with stunning views of the city. Guests can indulge in the hot tub and enjoy the meticulously designed garden spaces, providing a perfect retreat after a day of exploring the Vatican's treasures. - **Other amenities:** In addition to its luxurious offerings, Mama Shelter Roma features a well-equipped fitness centre, ensuring guests can maintain their workout routine. The hotel also boasts accessible facilities, daily housekeeping, and free toiletries to enhance the comfort of every stay. Guests have the convenience of electric car charging stations and complimentary rollaway beds for added flexibility. Additionally, the hotel provides gourmet dining options and a vibrant atmosphere, perfect for unwinding after a day of sightseeing. - **Neighborhood:** Vatican - **Nearby attractions:** St. Peter's Square - 2.4 km, Castel Sant'Angelo - 2.3 km, Sistine Chapel - 2.3 km [**Hotel Metropolis**](https://www.expedia.co.uk/Rome-Hotels-Hotel-Metropolis.h3604052.Hotel-Information) - **Why it's great for a luxury retreat:** Hotel Metropolis offers a luxurious stay with an excellent review rating of 8.2, making it a great option for travelers. This elegant hotel features premium bedding and suites designed for ultimate comfort. With a concierge service at hand, guests can easily access local attractions and exclusive experiences during their stay in the Vatican area. - **Other amenities:** The hotel includes a private hot tub, perfect for unwinding after a day of exploration. Guests can enjoy free toiletries and daily housekeeping for added convenience. The hotel also provides 24-hour airport shuttle services, ensuring seamless travel arrangements. Additional features include a separate living room in select suites, as well as onsite shopping to cater to guests’ luxury needs. A snack bar and romantic ambiance enhance the overall experience, making it a cherished choice for luxury travellers. - **Neighborhood:** Vatican - **Nearby attractions:** Castel Sant'Angelo - 1.2 km, Via del Corso - 1.5 km, Foro Italico - 1.9 km ## Top Vatican Hotel Reviews ![Starhotels Michelangelo](https://images.trvl-media.com/lodging/1000000/180000/176600/176543/6273dda6_y.jpg) ### Starhotels Michelangelo 10/10 Excellent "The rooms were beutiful. And all of the staff were great . I would definitely stay they again." [](https://expedia.co.uk/Rome-Hotels-Starhotels-Michelangelo.h176543.Hotel-Information) ![Trianon Borgo Pio](https://images.trvl-media.com/lodging/2000000/1450000/1443400/1443366/c122b911_y.jpg) ### Trianon Borgo Pio 10/10 Excellent "Nice place" [](https://expedia.co.uk/Rome-Hotels-Trianon-Borgo-Pio.h1443366.Hotel-Information) ![Hotel Isa](https://images.trvl-media.com/lodging/1000000/860000/856900/856829/abfd2e6c_y.jpg) ### Hotel Isa 10/10 Excellent "Hotel Isa is a wonderful hotel with spacious rooms in the Prati section of Rome- near the Vatican Amir Block or so off the Tiber - within walking distance of many major sites close to Metro and had a great staff breakfast was great the only issues you should be aware of is at the elevator goes up to the fifth floor and the rooftop restaurant for breakfast and bar is on the sixth where you have to walk up one flight to get to but outside of that it’s a great hotel" [](https://expedia.co.uk/Rome-Hotels-Hotel-Isa.h856829.Hotel-Information) ![Grand Hotel Olympic](https://images.trvl-media.com/lodging/1000000/80000/72900/72827/a302c22a_y.jpg) ### Grand Hotel Olympic 10/10 Excellent "Good place near Vatican. Room was good. Great breakfast." [](https://expedia.co.uk/Rome-Hotels-Grand-Hotel-Olympic.h72827.Hotel-Information) ![Hotel Dei Mellini](https://images.trvl-media.com/lodging/1000000/70000/63400/63399/db6d1bc9_y.jpg) ### Hotel Dei Mellini 10/10 Excellent "Cute Hotel, Great staff. Great location. Will definitely stay here again when visiting Rome" [](https://expedia.co.uk/Rome-Hotels-Hotel-Dei-Mellini.h63399.Hotel-Information) ![San Pietro Boutique Rooms](https://images.trvl-media.com/lodging/9000000/8380000/8378800/8378737/74470e4b_y.jpg) ### San Pietro Boutique Rooms 10/10 Excellent "Perfect location in Rome. The staff prepared everything for our arrival after their regular checkin time and we had no issues at all. They were extremely friendly and helpful. Our room was to the street, but very quiet and we enjoyed every second of our stay. " [](https://expedia.co.uk/Rome-Hotels-San-Pietro-Boutique-Rooms.h8378737.Hotel-Information) ![Hotel Adriatic](https://images.trvl-media.com/lodging/2000000/1620000/1615700/1615698/c74343a3_y.jpg) ### Hotel Adriatic 10/10 Excellent "Clean room and very friendly staff! Views from the room balcony and hotel terrace are wonderful! " [](https://expedia.co.uk/Rome-Hotels-Hotel-Adriatic.h1615698.Hotel-Information) ![Hotel Diplomatic](https://images.trvl-media.com/lodging/1000000/10000/6700/6603/bb6a8be2_y.jpg) ### Hotel Diplomatic 10/10 Excellent "This hotel is in quite the perfect location! We loved how convenient it was, and made our trip so much better. The room was cute and clean. We loved the staff, specially Gianluca. He was so friendly, kind and informative. We had such a great experience, thank you so much!! " [](https://expedia.co.uk/Rome-Hotels-Hotel-Diplomatic.h6603.Hotel-Information) ## Frequently asked questions ### Are you searching for a great accommodation for your luxury getaway to Vatican? ### What's the best luxury hotel in Vatican? ### What's there to see and do in Vatican? ### How can I get around Vatican? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Other - More ways to book - [4 Star Hotels in Prati ](https://www.expedia.co.uk/4Star-Prati-Rome-Hotels.s40-n6004847-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Rome City Centre ](https://www.expedia.co.uk/4Star-Rome-City-Centre-Rome-Hotels.s40-n553248633938945217-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Rome City Centre ](https://www.expedia.co.uk/5Star-Rome-City-Centre-Rome-Hotels.s50-n553248633938945217-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Rome ](https://www.expedia.co.uk/5Star-Rome-Hotels.s50-0-d179899.Travel-Guide-Filter-Hotels) - [Hotels near Bambino Gesu Hospital ](https://www.expedia.co.uk/Bambino-Gesu-Hospital-Hotels.0-l6159738-0.Travel-Guide-Filter-Hotels) - 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