Title: All Hotels by Best Western in Upstate South Carolina - 2026 Updated Prices | Expedia.co.uk [Upstate South Carolina Travel Guide](https://expedia.co.uk/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Holiday Rentals in Upstate South Carolina](https://expedia.co.uk/Upstate-South-Carolina-Holiday-Rentals.d553248635975748552.Travel-Guide-HolidayRentals)[Flights to Upstate South Carolina](https://expedia.co.uk/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.co.uk/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Upstate South Carolina Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Upstate-South-Carolina.d553248635975748552.Car-Hire-Guide)[Upstate South Carolina Holidays](https://expedia.co.uk/Upstate-South-Carolina.d553248635975748552.Holidays-City-Breaks) ![It is only a 1 mile hike to this beauty. View a video about it here: https://www.hdcarolina.com/episode/riley-moore-falls #Waterfall](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts # Search Hotels by Best Western in Upstate South Carolina from £60 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [2 Dec - 3 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2025-12-02&endDate=2025-12-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Dec - 4 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2025-12-03&endDate=2025-12-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975748552&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Upstate South Carolina Best Western Hotels ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/10000/800/708/338fc74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, blackout curtains, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/10000/800/708/cd95f3b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/800/708/2fe691fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/10000/800/708/c6283d85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Greenville Airport Inn Greenville 7.6/10 Good (1010) "This was the best room we stayed on our whole trip had a great deal smoking room and it was the best breakfast buffet that we had fresh yogurt everything about this hotel was nice" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vanessa £60 includes taxes & fees 8 Dec - 9 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Best-Western-Greenville-Airport-Inn.h708.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/d223eeb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed, Non Smoking, Microwave (with Sofabed) | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/188dc421.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/65f927f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517600/517561/a9edd66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Seneca-Clemson Seneca 8.4/10 Very good (637) "The stay was amazing " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tabatha £74 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Anderson-Hotels-Best-Western-Seneca-Clemson.h517561.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/d02ac737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/b1fdad7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking (with Sofabed) | Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/6c096589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast ](https://images.trvl-media.com/lodging/1000000/20000/19800/19764/1b324965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Spartanburg Northwest Spartanburg 8.2/10 Very good (815) "The staff was great ! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JANA £71 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Spartanburg-Hotels-Best-Western-Spartanburg-Northwest.h19764.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/fd542db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/c83ed6f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/a7c81686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/105600/105540/0689cad5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Travelers Rest Greenville Travelers Rest 7.6/10 Good (1000) "I always have a great stay here. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neil £78 includes taxes & fees 31 Dec - 1 Jan 2026 [](https://www.expedia.co.uk/Travelers-Rest-Hotels-Best-Western-Travelers-Rest-Greenville.h105540.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=553248635975748552&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Best-Western.0-0-d553248635975748552--bBestWestern.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Hotels-Best-Western.0-0-d553248635975748552--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Upstate South Carolina Hotel Reviews ![La Quinta Inn & Suites by Wyndham Greenville Haywood](https://images.trvl-media.com/lodging/1000000/170000/165800/165759/89ed0b3d_y.jpg) ### La Quinta Inn & Suites by Wyndham Greenville Haywood 10/10 Excellent "The staff is so friendly and they are very accommodating. Eddie from the front desk is always kind. Good breakfast " [](https://expedia.co.uk/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Haywood.h165759.Hotel-Information) ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "The room was clean and check-in was easy breakfast. The next morning was wonderful." [](https://expedia.co.uk/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ![Best Western Plus Greenville I-385 Inn & Suites](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/20a0c66a_y.jpg) ### Best Western Plus Greenville I-385 Inn & Suites 10/10 Excellent "Smooth and perfect. Queen Suite is par excellence. Neat clean and all in place and more than what was expected. " [](https://expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Beautiful place, awesome staff!" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "Great stay. Enjoyed Greenville and the Embassy Suites" [](https://expedia.co.uk/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![DoubleTree by Hilton Greenville Woodruff Road](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/f59bfe6c_y.jpg) ### DoubleTree by Hilton Greenville Woodruff Road 10/10 Excellent "." [](https://expedia.co.uk/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent "They did a wonderful job everything was great!!!" [](https://expedia.co.uk/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Room was great. Joe at check in was more than helpful." [](https://expedia.co.uk/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6a375dd3_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "Loved the location, attention to design details in all spaces, complimentary cocktails and delicious lunch in hotel restaurant. Really used the swamp rabbit trail right outside…" [](https://expedia.co.uk/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - More ways to book - [Anglewood Hotels](https://www.expedia.co.uk/Anglewood-Hotels.d553248635975857985.Travel-Guide-Hotels) - [Caravan Parks in Duncan](https://www.expedia.co.uk/Duncan-Caravan-Parks.d6761-aaCaravanParks.Travel-Guide-Accommodation) - [Duncan Hotels](https://www.expedia.co.uk/Duncan-Hotels.d6761.Travel-Guide-Hotels) - [Marriott Hotels & Resorts in Elgin](https://www.expedia.co.uk/Elgin-Hotels-Marriott-Hotels-Resorts.0-0-d6051125--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [Enoree Hotels](https://www.expedia.co.uk/Enoree-Hotels.d3000353124.Travel-Guide-Hotels) - [Fingerville Hotels](https://www.expedia.co.uk/Fingerville-Hotels.d3000353129.Travel-Guide-Hotels) - [Fountain Inn Hotels](https://www.expedia.co.uk/Fountain-Inn-Hotels.d6348218.Travel-Guide-Hotels) - 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[Flights from Miami (MIA) to Spartanburg (SPA)](https://www.expedia.co.uk/lp/flights/mia/spa/miami-to-spartanburg) - [Flights from Jackson (MKL) to Spartanburg (SPA)](https://www.expedia.co.uk/lp/flights/mkl/spa/jackson-to-spartanburg) - [Flights from Chicago (ORD) to Spartanburg (SPA)](https://www.expedia.co.uk/lp/flights/ord/spa/chicago-to-spartanburg) - [Flights from Greenville (PGV) to Spartanburg (SPA)](https://www.expedia.co.uk/lp/flights/pgv/spa/greenville-to-spartanburg) - [Flights from Richmond (RIC) to Spartanburg (SPA)](https://www.expedia.co.uk/lp/flights/ric/spa/richmond-to-spartanburg) - [Flights from South Bend (SBN) to Spartanburg (SPA)](https://www.expedia.co.uk/lp/flights/sbn/spa/south-bend-to-spartanburg) - [Flights from Seattle (SEA) to Spartanburg (SPA)](https://www.expedia.co.uk/lp/flights/sea/spa/seattle-to-spartanburg) - [Flights from San Francisco (SFO) to Spartanburg (SPA)](https://www.expedia.co.uk/lp/flights/sfo/spa/san-francisco-to-spartanburg) - [Flights from Weyers Cave (SHD) to Spartanburg (SPA)](https://www.expedia.co.uk/lp/flights/shd/spa/weyers-cave-to-spartanburg) - 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