- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Texas Medical Center luxury hotels

1. Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterTexas Medical Center
8.6 out of 10, Excellent, (2,255 reviews)
The price is £88
includes taxes & fees
29 Nov - 30 Nov

2. Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,021 reviews)
cleanliness Tranquil luxury near Houston's Museum District features a full-service spa, outdoor pool, and indulgent champagne service.
The price is £206
includes taxes & fees
13 Dec - 14 Dec

3. Sentral Forme Houston
Sentral Forme HoustonSouth Central Houston
9.2 out of 10, Wonderful, (102 reviews)
The price is £189
includes taxes & fees
13 Dec - 14 Dec

4. Rusk House Serviced Apartments
Rusk House Serviced ApartmentsDowntown Houston
9.4 out of 10, Exceptional, (569 reviews)
cleanliness Sophisticated city centre retreat with luxurious apartments and full kitchen amenities in Houston's heart.
The price is £128
includes taxes & fees
21 Nov - 22 Nov

5. Houston Grand Hotel - River Oaks
Houston Grand Hotel - River OaksThe Galleria
9.2 out of 10, Wonderful, (528 reviews)
cleanliness Immerse in indulgent relaxation at this 5-star Houston retreat with a full-service spa, outdoor pool, and attentive staff service.
The price is £150
includes taxes & fees
22 Nov - 23 Nov

6. Hotel Granduca Houston
Hotel Granduca HoustonThe Galleria
9.2 out of 10, Wonderful, (1,001 reviews)
cleanliness Tuscan elegance redefines Houston luxury with poolside cocktails, concierge service, and Remi restaurant dining.
The price is £204
includes taxes & fees
29 Nov - 30 Nov

7. The Westin Galleria Houston
The Westin Galleria HoustonThe Galleria
9.2 out of 10, Wonderful, (1,000 reviews)
The price is £201
includes taxes & fees
27 Nov - 28 Nov

8. The Laura Hotel, Houston Downtown, Autograph Collection
The Laura Hotel, Houston Downtown, Autograph CollectionDowntown Houston
9.2 out of 10, Wonderful, (1,288 reviews)
cleanliness Indulge in urban refinement at this Houston city centre hotel featuring a full-service spa, outdoor pool, and southern cuisine restaurant.
The price is £174
includes taxes & fees
22 Nov - 23 Nov

9. The Lancaster Hotel
The Lancaster HotelDowntown Houston
9.8 out of 10, Exceptional, (1,002 reviews)
cleanliness Luxurious city centre Houston retreat offers pillowtop beds, stocked minibars, and exceptional dining in the Theatre District.
The price is £213
includes taxes & fees
27 Nov - 28 Nov

10. JW Marriott Houston Downtown
JW Marriott Houston DowntownDowntown Houston
9.0 out of 10, Wonderful, (1,000 reviews)
cleanliness Indulge in spa treatments and upscale comfort at this city centre Houston luxury hotel where modern elegance meets five-star service.
The price is £223
includes taxes & fees
20 Nov - 21 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Texas Medical Center
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() InterContinental Houston by IHG | 9.4 Exceptional 1,009 reviews | View | ||||||
![]() Blossom Hotel Houston, Curio Collection by Hilton | 9.0 Wonderful 3,787 reviews | View | ||||||
![]() Houston Marriott Medical Center/Museum District | 9.0 Wonderful 1,000 reviews | View | ||||||
![]() The Westin Houston Medical Center/Museum District | 9.2 Wonderful 1,287 reviews | View | ||||||
![]() Hilton Houston Plaza/Medical Center | 8.6 Excellent 2,255 reviews | View |



































